1,721,053 research outputs found
Glycosylated liposomes: a potential tool for the detection and treatment of bacterial infections
No full textBacterial infections pose a huge concern for human health in terms of increased morbidity, mortality and healthcare costs. Two main issues contribute to render the treatment of some infectious diseases a difficult task: anti-microbial resistance (AMR) and the development of microbial biofilms.The aim of the work described in this thesis is the development of liposomes that, properly functionalized and loaded, could have a potential application in the diagnosis of bacterial infections and in the relative therapy. The chosen strategy to achieve the selective recognition of bacteria by liposomes is based on the decoration of vesicles surface with saccharide moieties that might ascribe to them specificity toward lectins and carbohydrate-receptors located on microbial cells. For what concerns the diagnosis, a further functionalization of the lipid bilayer capable of generating a specific optical response upon the interaction with pathogens is required; to achieve this goal, the chromo-responsive polydiacetylene (PDA) liposomes containing the π-conjugate “ene-yne” backbone were selected as suitable vesicular platform
Evolution of larval development in marine gastropods
Full text linkIn this thesis I have investigated several aspects of the evolution of larval development in Caenogastropoda, the largest extant radiation of gastropod molluscs, probably also the largest radiation of extant marine invertebrates. Within marine invertebrates, the gastropods provide unique tools to perform studies on the evolution of larval development: important aspects of larval development are reflected in the morphology of their embryonic/larval shell, the protoconch, which is very often retained at the apex of the adult shell, allowing for inference on larval ecology of the organisms by the study of the adults, also fossil. This work is aimed at shedding light on two of the most controversial issues about larval development evolution: poecilogony and secondary reacquisition of planktotrophy
CONTRIBUTION TO THE KNOWLEDGE OF PROSERIATA (PLATYHELMINTHES: RHABDITOPHORA) OF THE AZORES
No full textEffetto degli oli essenziali di Erigeron canadensis e Myrtus communis sullo sviluppo di funghi patogeni in vitro
No full textBIODIVERSITÀ CRIPTICA: IL CASO DI GYRATRIX HERMAPHRODITUS EHERENBERG, 1831 (PLATYHELMINTHES: KALYPTORHYINCHIA)
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Impact of experimental trampling on meiofauna inhabiting rocky intertidal bottoms at the Asinara Island MPA (NW Mediterranean)
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Composition and antifungal activity of two essential oils of Hyssop (Hissopus officinalis L.)
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