1,492 research outputs found

    nbellive/CRISPRi_screen_HL60_pub: v1.0.0

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    Github repository for 'Cell migration CRISPRi screens in human neutrophils reveal regulators of context-dependent migration and differentiation state,' Nathan M. Belliveau, Matthew J. Footer, Emel Akdogan, Aaron P. van Loon, Sean R. Collins, Julie A. Theriot doi: https://doi.org/10.1101/2022.12.16.52071

    Tour de Table: Farm to Fork Law Update two

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    The article is the second of a periodic update of the progressing Farm to Fork (F2F) laws in the making. This second edition makes an appraisal of the legislative initiatives in the Farm to Fork Strategy by making a ‘Tour de Table’. We report on the main changes and developments of selected legal actions proposed, notably: the umbrella actions (section II); the actions relevant for food safety-technology, quality, and information (sections III); as well as food business responsibility (section IV). We conclude with our observations about the future of the F2F laws in the EU (section V)

    Tour de Table: Farm to Fork Law Update

    No full text
    The article is the second of a periodic update of the progressing Farm to Fork (F2F) laws in the making. This second edition makes an appraisal of the legislative initiatives in the Farm to Fork Strategy by making a ‘Tour de Table’. We report on the main changes and developments of selected legal actions proposed, notably: the umbrella actions (section II); the actions relevant for food safety-technology, quality, and information (sections III); as well as food business responsibility (section IV). We conclude with our observations about the future of the F2F laws in the EU (section V)

    Rigid polyurethane foams with halogen‐free flame retardants: Thermal insulation, mechanical, and flame retardant properties

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    Akdogan, Emre/0000-0003-1505-9323; Ureyen, Mustafa Erdem/0000-0002-9055-3228WOS: 000488228100015Rigid polyurethane foam (RPUF) composites with triphenyl phosphate (TPhP), aluminum trihydrate (ATH), and zinc borate (ZnB) alone, as well as their binary blends, were prepared via a one-shot process. the amount of flame retardant (FR) or FR blend was varied from 10 to 50% by polyol weight percentage, and the weight fraction of the blends was also fixed at 40%. the effects of additives on thermal insulation, mechanical, and flame retardancy properties of the composites were investigated. Thermal conductivity of the neat foam (RPUF) decreased from 22.53 to 21.04-21.58 mW m(-1) K-1. the compressive strength of foams displayed an increase with increasing the amount of TPhP, ATH, and ZnB till 40% by weight. the limited oxygen index values of all foams increased and the flame spread rates of all foams significantly decreased. It was also observed that the flame was self-extinguished in some cases. the cone calorimeter test results indicated that the FR additives improved the flame retardancy of the RPUF. (c) 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 47611

    Coexistence of perpendicular and in-plane exchange bias using a single ferromagnetic layer in Pt/Co/Cr/CoO thin film

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    We studied the temperature dependence of magnetization and exchange bias in a Pt/Co/Cr/CoO multilayer thin film. These magnetic multilayers are of particular interest since the easy axis of ultra-thin Co is strongly affected by the interfacial anisotropies of neighbouring Pt and Cr layers. The room temperature measurements show that the sample has a magnetic easy axis only in the film plane. However, upon cooling the sample, the easy axis of the magnetization departs from its initial orientation and typical easy-axis hysteresis loops are obtained for both in-plane and perpendicular directions. In accordance with this change in the magnetization direction at lower temperatures, the sample shows an unexpected coexistence of perpendicular and in-plane exchange bias below the antiferromagnetic transition of CoO. The temperature dependence of the exchange bias field for both directions is also significantly different. Along the film plane, the exchange bias field monotonically decreases and disappears at 220 K with increasing temperature. For the perpendicular direction, however, the exchange bias field increases and reaches a maximum value at 80 K. Then it decreases and disappears at 150 K with further increasing temperature. The mechanisms behind this anomalous temperature dependence of the exchange bias as well as the step-like behaviour in the hysteresis curves are discussed. Copyright (C) EPLA, 201

    Equity market integration in the Middle East and North Africa: in search for diversification benefits

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    The purpose of this paper is to investigate the MENA’s potential for portfolio diversification benefits by examining long run equity linkages with daily data over the 1998-2004 periods. Our analysis is based on several co-integration analyses and an extension of Akdogan measures of financial integration. We first compare financial integration with the EU and the US. Results suggest that the MENA region is growingly segmented from both regions. Although integration is relatively higher with the EMU, diversification benefits for both EU and US investors are possible since segmentation levels appear converging. At the country level, our analysis displays no evidence of regional integration, thereby suggesting potential for local diversification. Integration scores also show that Egypt and Turkey should be relatively more appealing for the US investor and Israel, and Jordan and Morocco for the EU investor. Lebanon and Tunisia are two specific cases displaying opposite dynamics. A moving average analysis also shows that financial events, internal reforms and political shocks do not affect the region stock market linkages homogeneously; real economic integration seems to diminish financial segmentation. Finally, we approach the issue of short run linkages with a VAR-VECM methodology. Impulse response analysis shows that all markets seem to respond to each other, but that Turkey is unaffected by shocks occurring in the other markets. This ultimately raises questions on the dynamics of intra-regional contagion.Stock Market Integration, Portfolio Diversification, MENA markets, Time-varying methods.

    Modelling the dynamics of granular particle interactions in a vortex reactor using a coupled DPM-KTGF model

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    CITATION: Oyegbile, B., Akdogan, G. & Karimi, M. 2020. Modelling the dynamics of granular particle interactions in a vortex reactor using a coupled DPM-KTGF model. South African Journal of Chemical Engineering, 34:31-46, doi:10.1016/j.sajce.2020.05.008.The original publication is available at http://www.sciencedirect.comPublication of this article was funded by the Stellenbosch University Open Access FundENGLISH ABSTRACT: In this work, a shear-driven two-phase particulate flow of monodispersed and polydispersed granular materials has been studied experimentally and numerically as a function of solids concentration and restitution coefficients for different operating speeds N (70 -130 rpm) in a lab-scale rotor-stator agglomeration reactor. A coupled computational fluid-particle dynamics (CFPD) model was developed consisting of a steady-state flow field of the continuous phase coupled to a transient particle tracking of the discrete phase. This was achieved via a one-way coupling between the continuous and the discrete phase by including the effect of drag, lift, pressure gradient, virtual mass forces, as well as granular collisional forces in describing the particle-particle, particle-wall and the fluid-particle interactions. The spatiotemporal evolution of the flow pattern, discrete phase properties, and influence of the operating conditions on the granular properties were characterized. The validation of the numerical model developed in this study was carried out based on the theoretical analysis of the rotor-stator flow and the PIV flow measurements. The results showed that the particle sizes were uniformly distributed within the reactor after steady-state conditions, while a small region of high particle concentration was observed near the rotor due to low vorticity and turbulent intensity around the region. In terms of the operating conditions, the restitution coefficients and the operating speeds do not have a significant influence on the granular properties apart from the small region around the shaft where there is a correlation between these parameters. The particle sizes, however, show a positive correlation with the granular properties. Also, a wider particle size distribution was observed axially towards the stator, which might be attributed to the pumping effect of the Batchelor flow in this direction. It was also concluded that the discrete phase velocity does not seem to vary significantly with the restitution coefficients. Furthermore, the vertical velocity and vorticity profiles give a reasonably good agreement between the CFPD model predictions and PIV measurements. The minor observed deviations were mainly due to some of the experimental limitations rather than the robustness of the CFPD model or the numerical code.https://www.sciencedirect.com/science/article/pii/S1026918520300214Publisher's versio

    Next-to-leading order QCD analysis of the spin structure function g1

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    Adeva B, Akdogan T, Arik E, et al. A next-to-leading order QCD analysis of the spin structure function g(1). Phys.Rev. D. 1998;58(11): 112002.We present a next-to-leading order QCD analysis of the presently available data on the spin structure function g(1) including the final data from the Spin Muon Collaboration. We present results for the first moments of the proton, deuteron, and neutron structure functions, and determine singlet and nonsinglet parton distributions in two factorization schemes. We also test the Bjorken sum rule and find agreement with the theoretical prediction at the level of 10%. [S0556-2821(98)07117-3]
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