45,534 research outputs found

    Bernard Williams

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    An edited multi-author volume assessing the moral philosophy of the late British philosopher Bernard Williams. Contributors: Adrian Moore, John Skorupski, Alan Thomas, Robert B Louden, Michael Stocker, A. A. Long, Edward Crai

    An open reply to "What is going on at the Library of Congress?" by Thomas Mann

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    This is an open response to a report by Thomas Mann at the Library of Congress concerning changes in cataloging. The author contends that, although the current changes at the Library of Congress are suspect, changes are imminent and experienced catalogers must offer positive suggestions for change, otherwise they will be ignored by management

    The construction of Karen Karnak: The multi-author-function

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    This thesis is situated within the comparatively recent developments of Web 2.0 and the emergence of interactive WikiMedia, and explores the mode of authorship within a Read/Write culture compared to that of a Read/Only tradition. The hypothesis of this study is that the role of the audience has become merged with the author, and as such, represents new functions and attributes, distinct from a more conventional concept of authorship, in which the roles of audience and author are more separate. Read/Write and participatory culture, as defined by this study, is focused on collaboration, and includes the influences of D.I.Y. culture, Open-Source practices and the production of text by multiple authors. Multi-authorship presents a re-thinking of several concepts which support the notion of the individual author, since the focus of multi-authorship is not on attribution and ownership of a finished text, but on the continued malleability of a text. Modes of multi-authorship, demonstrated in the use of the pseudonyms Alan Smithee and Karen Eliot, represent declarative authors whose names signify multiple origins, whilst concurrently indicating a distinct body of work. The function of these names form an important context to this study, since primary research involves the construction of an experimental mode of multi-authorship utilising WikiMedia technology and the interaction of thirty nine participants, who are invited to create a body of work under the collective pseudonym Karen Karnak. The data generated by this experiment is analysed using aspects of Michel Foucault's author-function to identify and determine power structures inherent in the WikiMedia context. The interplay of power structures, including concepts such as identity, ownership and the body of work, affect the resulting mode of authorship and contribute to the construction of Karen Karnak, suggesting further areas of research into the emerging multi-author

    Advisor, 1963

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    A 1963 portrait of congressman Thomas Ashley whispering into the ear of Lyndon B. Johnson. Terms associated with the photograph are: Johnson, Lyndon B. (Lyndon Baines), 1908-1973 | presidents | Ashley, Thomas W. (Thomas William Ludlow), 1923-2010 | legislators--United States | portrait

    Aggregate wheat and barley production in Idaho, 1970

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    Bulletin no. 518 Moscow :Agricultural Experiment Station, University of Idaho, College of Agriculture,1970. Roger B. Long and Monica E. Thomas. 29 p. :ill. ;28 cm

    Conditional immortalization of human B cells by CD40 ligation

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    It is generally assumed that human differentiated cells have a limited life-span and proliferation capacity in vivo, and that genetic modifications are a prerequisite for their immortalization in vitro. Here we readdress this issue, studying the long-term proliferation potential of human B cells. It was shown earlier that human B cells from peripheral blood of healthy donors can be efficiently induced to proliferate for up to ten weeks in vitro by stimulating their receptor CD40 in the presence of interleukin-4. When we applied the same stimuli under conditions of modified cell number and culture size, we were surprised to find that our treatment induced B cells to proliferate throughout an observation period of presently up to 1650 days, representing more than 370 population doublings, which suggested that these B cells were immortalized in vitro. Long-term CD40-stimulated B cell cultures could be established from most healthy adult human donors. These B cells had a constant phenotype, were free from Epstein-Barr virus, and remained dependent on CD40 ligation. They had constitutive telomerase activity and stabilized telomere length. Moreover, they were susceptible to activation by Toll-like receptor 9 ligands, and could be used to expand antigen-specific cytotoxic T cells in vitro. Our results indicate that human somatic cells can evade senescence and be conditionally immortalized by external stimulation only, without a requirement for genetic manipulation or oncoviral infection. Conditionally immortalized human B cells are a new tool for immunotherapy and studies of B cell oncogenesis, activation, and function

    Interview with Eliza Jane Coward Thomas

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    Eliza Jane Coward Thomas is interviewed by Lorraine Crittenden on May 6, 1986 as a part of the Western North Carolina Tomorrow Black Oral History Project. Thomas was born on Long Branch in Cullowhee in 1893. She talks about her childhood in Jackson County where she grew up living with her uncle in a tight knit community. She describes Asheville and working for E. B. Glenn, a doctor at Meriwether Hospital, watching his children, cleaning, and cooking and then working for the Frye family. Thomas had a good experience with both families and good relationships with white people in general her entire life

    Thomas Roy McLean

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    Notes - This is the story of Mr. Thomas Roy McLean - his marriage to Helen, his life in Hay River and Athabasca, and his careers in radio and at the creamery. Mr. McLean ran an appliance store in Athabasca and was part of bringing electricity to the area. His store and neighbouring businesses are described in great detail in this document (3 pages

    A compleat collection of devotions : both publick and private : taken from the apostolical constitutions, the ancient liturgies, and the Common prayer book of the Church of England ... [etc.].

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    Signatures: [pi]¹, A?, A-Y?, Z?, a-h?, i? (final verso blank).; Attributed to Thomas Deacon.; Label: Library of the Congregation of U.B. of the Borough of Bethlehem and its vicinity, no. 877.; Signature; B. Ingham.; An appendix in justification of the foregoing undertaking ... has separate title and pagings.; BM,; ESTC

    Thomas B. Edsall on the Convicted Felon Trump, and Walter J. Ong’s Thought

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    In my wide-ranging 3,300-word essay, I first briefly introduce the life and work of the American Jesuit Renaissance specialist and cultural historian and pioneering media ecology theorist Walter J. Ong (1912-2003; Ph.D. in English, Harvard University, 1955). Then I discuss Thomas B. Edsall’s op-ed column “Trump Would Be Long Gone if Only We Could . . . ” (dated June 12, 2024) in the New York Times
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