877 research outputs found
La Vestale 'incesta'
No full textMarcello Salvadore: La Vestale incesta.
Dionysius of Halicarnassus, Pliny the Younger and Plutarch are the sources
of a detailed account of Vestalis incesta’s punishment: they say that she was
sentenced to death. Dionysius adds that there was no after death ritual.
Modern scholars generally accept what the three authors assert. In this article
the author surmises that the Vestalis incesta, together with the parricida, was
not condemned to death: both of them were sentenced to a particular kind
of banishment from the Society
De Lope a Celano: la adaptación italiana de "Los tres diamantes"
No full textAbstract
This paper explores an Italian adaptation of Lope de Vega’s play Los tres diamantes, written in the
second part of the seventeenth century. Its author, Carlo Celano, was a famous writer of opere regie,
i.e., adaptations of Spanish comedies of situation. The analysis focuses on the way in which the
adaptation of the Aristotelian units of space and time leads to a reduction of the characters and a
simplification of the situation, although this is compensated by enriching its ludic component. This
last trait can be also observed in a previous re-elaboration of Lope’s comedy, the scenario of the
Commedia dell’arte titled Il cavaliere dai tre gigli d’oro
Due note critiche
No full textMarcello Garzaniti
Answers to Criticism
The author answers to the critics of M. Capaldo and A.Giambelluca Kossova with the aim to bring the different proposed questions back into the sphere of scientifi c dialogue
Cerebral Ischemic Events Ipsilateral to Carotid Artery Stenosis. The Carotid Asymptomatic Stenosis (CARAS) Observational Study: First Year Preliminary Results
No full textObjective: To report the characteristics of the prospective observational cohort study "Carotid Asymptomatic Stenosis (CARAS)", including patients with asymptomatic carotid stenosis under medical treatment and their first year of follow-up, in order to estimate the risk of cerebral ischemic events.Methods: This is a prospective observational cohort study of CARAS>60% (Nascet criteria) patients, identified in a single duplex-ultrasonography (DUS) vascular laboratory (trail registration N: NCT04825080). Patient's enrollment started in January 2019 and ended in March 2020 with the follow-up conclusion scheduled in December 2025. The aimed sample size was calculated at 300 patients for a 5-year follow-up. The primary outcome were the incidence of ipsilateral neurologic ischemic events (stokes and transient ischemic attacks [TIA]), plaque progression rate, and survival. The follow-up was scheduled at six-month intervals for clinical visit and annually for DUS examination.Results: a total of 307 patients completed the first follow-up year. The mean age was 81 +/- 4 years, 55% were male. Contralateral stenosis >60% was present in 90 (29%) patients. Antiplatelet therapy and statins adherence was 80% and 88%, respectively. During the first year, 3 ispilateral strokes (1%) and 4 TIAs (1.3%) occurred, for a total of 2.3% ipsilateral ischemic events. During the first year, 43 (14%) plaques had a stenosis progression, which was correlated with the occurrence of neurological events (9.3% vs. 1.1%, P=.001, OR: 8.9; 95%CI: 1.9-41); 6 deaths (2%) occurred in the same period.Conclusion: the preliminary one-year results of this prospective study suggest that the overall rate of any ipsilateral ischemic event, and specifically ipsilateral strokes, correlates with plaque progression. (c) 2022 Elsevier Inc. All rights reserved
The mid-term results of the Carotid Asymptomatic Stenosis (CARAS) observational study
No full textIntroduction: Carotid endarterectomy (CEA) in patients with asymptomatic carotid stenosis (ACAS) remains a subject of debate. Current recommendations are based on randomized trials conducted over 20 years ago and improvements in medical therapies may have reduced the risk of cerebral ischemic events (CIE). This study presents a mid-term analysis of results from an ongoing prospective observational study of ACAS patients to assess their CIE risk in a real-world setting. Methods: This is a prospective observational cohort study of patients with ACAS >60 % (NASCET criteria) identified in a single duplex ultrasonography (DUS) vascular laboratory (trial registered: NCT04825080). Patients were not considered for CEA due to their short life expectancy (<3 year) or absence of signs of plaque vulnerability (ulceration, ipoechogenic core). Patient enrollment started in January 2019 and ended in March 2020 with a targeted sample size of 300 patients.A 5-year follow-up was scheduled. Clinical characteristics, risk factors, and medical therapies were documented, and, when necessary, the best medical therapy (BMT), involving antiplatelet agents, blood pressure control, and statins, was recommended during clinical visits. The primary endpoint was to asses CIEs (including strokes, transient ischemic attacks, amaurosis-fugax) ipsilateral to ACAS along with plaque progression rate and patients survival. Follow-up involved annual clinical visit and carotid DUS examination, complemented by telephone interviews at six-month intervals. Results: The study included 307 patients, with an average age of 80 ± 7 years, of whom 55 % were male. Contralateral stenosis exceeding 60 % was present in 61 (20 %) patients. Seventy-seven percent of patients were on BMT. At a mean follow-up of 41±9 months, 7 ispilateral strokes and 9 TIAs occurred, resulting in 14 CIEs (2 patients experienced both TIA and stroke). According to Kaplan-Meier analysis, the 4-year CIE rate was 6±2 %, with an annual CIE rate of 1.5 %. Fifty-eight (19 %) patients had a stenosis progression which was associated with a higher 4-year estimated CIE rate compared to patients with stable plaque (10.3 % vs 3.2 %, P=.01). Similarly, a contralateral carotid stenosis >60 % was associated with a higher 4-year estimated CIE rate: 11.7 % vs 2.9 %, P=.002. These factors were independently associated with high risk for CIE at the multivariate COX analysis: Hazard Ratio (HR): 3.2; 95 % Confidence Interval: 1.1-9.2 and HR: 3.6; 95 % CI: 1.2-10.5. Conclusion: The mid-term results of this prospective study suggest that the incidence of CIE in ACAS patients should not be underestimated, with plaque progression and contralateral stenosis serving as primary predictors of CIEs
La tenuta di Zambra nell’agro romano oltre la Convenzione Europea del Paesaggio. Un’analisi geografica a scala locale
No full textA partire dalla Tenuta di Zambra, ambito territoriale storicamente ben definito della Campagna di Roma, attraverso fonti documentarie storiche e cartografiche, gli autori ricostruiscono, avvalendosi della metodologia GECOAGRI LANDITALY e dei GIS, le trasformazioni del paesaggio rurale che da tenuta diventa podere la cui parcellizzazione determina processi di polverizzazione e rifunzionalizzazione. Il paesaggio rurale di Zambra nonostante la CEP registra negli ultimi decenni cambiamenti di uso del suolo, cementificazione e diminuzione della superficie agricola. Processi che compromettono i valori ambientali, culturali ed economici di questo lembo di terra che in quanto paesaggio rurale della vita quotidiana doveva essere tutelato, valorizzato e salvaguardato
Diagnosis and management of acute conditions of the extracranial carotid artery
No full textSymptomatic carotid stenosis and carotid dissection are acute conditions of extracranial cerebrovascular vessels determining transient ischemic attack or stroke. Medical, surgical, or endovascular management are different options to treat these pathologies. This narrative review focused on the management, from symptoms to treatment, of the acute conditions of extracranial cerebrovascular vessels, including post-carotid revascularization stroke. Symptomatic carotid stenosis ( > 50% according to North American Symptomatic Carotid Endarterectomy Trial criteria) with transient ischemic attack or stroke benefits from carotid revascularization-primarily with carotid endarterectomy associated with medical therapy-within 2 weeks from symptom onset to reduce the risk of stroke recurrence. Different from acute extracranial carotid dissection, medical management with antiplatelet or anticoagulant therapy can prevent new neurologic ischemic events, considering stenting only in case of symptom recurrence. Stroke after carotid revascularization can be associated with the following etiologies: carotid manipulation, plaque fragmentation, or clamping ischemia. Medical or surgical management is therefore influenced by the cause and timing of the neurologic events after carotid revascularization. Acute conditions of the extracranial cerebrovascular vessels include a heterogeneous group of pathologies and correct management can reduce symptom recurrence substantially. & COPY; 2023 Elsevier Inc. All rights reserved
The Pragmatics of Literature
No full textThis translation of the work of one of the founding fathers of literary structuralism and semiotics in Italy is a timely introduction to the theoretical study of literary communication. Marcello Pagnini is a leading figure in the post-structuralist endeavor to return the text to something resembling its social matrix. He explores not only the dynamics of the author/reader rapport but also the connections between the literary text and its sociocultural and historical contexts
Routine use of CO2: forget iodinated-contrast injuries during complex aortic procedures
No full textN
Association between index symptom and timing on perioperative stroke rate in patients undergoing carotid endarterectomy
No full textBackground and Purpose: Carotid endarterectomy (CEA) in symptomatic carotid stenosis (SCS) may have a higher risk of perioperative stroke due to disease severity or hemorrhagic conversion. This study aimed to evaluate CEA outcomes for SCS and examine causes of post-operative stroke based on intervention timing and preoperative symptoms. Methods: All CEAs performed for SCS from 2012 to 2023 across two metropolitan hospitals were analyzed. CEAs were performed with general anesthesia, patching, and shunting. Post-operative (30-day) strokes were classified as technical, hemorrhagic, or embolic and were evaluated by timing (<48 h, 48h–2 weeks, >2 weeks) and preoperative symptoms (TIA/amaurosis fugax, minor stroke, moderate-severe stroke, crescendo TIAs/stroke in evolution). Stroke severity was assessed using the modified Rankin Scale (mRS). Results: Among 664 CEAs, post-operative stroke occurred in 3.0 % of cases. Timing significantly influenced stroke rates: 5.7 % <48 h, 4.0 % between 48h–2 weeks, and 1.4 % >2 weeks (P = .04). Preoperative symptoms also affected stroke rates, with highest rates following crescendo TIAs/stroke in evolution (7.5 %, P = .02). Early CEA (<48 h) independently increased stroke risk (odds ratio 5.6, P = .04), and hemorrhagic strokes were associated with <48 h interventions (P = .005). Major strokes occurred in 1.1 % of cases, linked to preoperative symptoms (P = .05), but not intervention timing. Conclusions: CEA for SCS carries an acceptable stroke risk overall, though early intervention (<48 h) increases hemorrhagic stroke risk. Major strokes are more frequent following crescendo TIA/stroke in evolution, with no association to timing
- …
