45 research outputs found
Digital Learning Techniques-Recent Trends:A perspective from classroom teaching and learning
Get PDFTechnology tools for collaboration, communication, social networking, and user-generated content have transformed the traditional ways of learning. When applied efficiently, technology enables teachers and students to participate actively, produce and co-create information through the use of digital learning tools. They can help students innovate and learn strategies that combine in-person with virtual learning experiences. The use of digital technologies in the class room encourage active knowledge, comprehension construction, analysis, and exploration on the part of the learners, and which allow for remote communication as well as data division to take place between teachers and/or learners in different physical classroom
The prevalence of ocular manifestations in road traffic accidents treated at a rural tertiary care hospital in south india: a cross sectional study
Get PDFBackground: Ocular injuries following road traffic accidents (RTA) is one of the common causes of ophthalmological morbidity and unilateral blindness. The aim of this study was to document the epidemiological pattern of ocular injures caused by RTA in a cross-sectional population brought to a tertiary care centre in rural southern India.Methods: After receiving institutional ethics committee approval, all patients over the age of 10 years, who came to the emergency department (ED) of this rural tertiary care centre with alleged history of RTA, during the period, July-December 2015 were serially enrolled to participate in the study after obtaining written informed consent. The sample size for 95% confidence level and precision of 5% was calculated to be 191.Results: Out of the 832 cases of RTA presenting to the ED, 191 (23%) had ocular injuries. There were 186 (97.38%) closed globe injuries and 5 (2.6%) open globe injuries. Eight (4.1%) patients with ocular injuries had no perception of light in the affected eye after the accident. The commonest injury was periorbital edema and ecchymosis (68.6%) followed closely by eyebrow laceration (63.9%) and lid laceration (48.2 %). The commonest anterior and posterior segment injuries were traumatic optic neuritis (6.3%) and vitreous or retinal haemorrhage 4 (2.09%) respectively.Conclusions: In this study, the prevalence of ocular involvement in RTA was is 23%. Most of the injuries were closed globe injuries and periorbital edema and ecchymosis were the commonest type of injury occurring followed by eyebrow and lid laceration. </jats:p
Climate, Community, & Corporations
No full textabstract: In 2016, the news of the protests at Standing Rock broke through the nation. The Sioux Falls tribe of North Dakota embarked on a fight to protect their sacred lands and water from potential desecration and pollution. The documentary film, Awake, a Dream from Standing Rock, was released the following year depicting the resistance movement created at the camps at Standing Rock. This film became the subject matter for my project in which a film screening followed by a post-show discussion to explore the resistance movement and creative choices of the film as they pertain to indigenous rights, climate change, and corporations. The panel included Leroy Hollenback, a corporate social responsibility director from a Global 500 company, and Monte Yazzie, a Phoenix activist and film critic. The panel analyzed the artistic choices the filmmakers took and how that shaped the message of the film. Furthermore, the panel discussed what policy implications the film brought to light. In the end, indigenous resistance in efforts to protect Earth's biodiversity is present globally, making Standing Rock a modern case study that can instruct future movements
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
Get PDFGenetic factors have been implicated in stroke risk, but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke and its subtypes in 3,548 affected individuals and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 affected individuals and 6,281 controls. We replicated previous associations for cardioembolic stroke near PITX2 and ZFHX3 and for large vessel stroke at a 9p21 locus. We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10<sup>−11</sup>; odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28–1.57). All four loci exhibited evidence for heterogeneity of effect across the stroke subtypes, with some and possibly all affecting risk for only one subtype. This suggests distinct genetic architectures for different stroke subtypes
Skyler and Bliss
No full textHong Kong remains the backdrop to the science fiction movies of my youth. The city reminds me of my former training in the financial sector. It is a city in which I could have succeeded in finance, but as far as art goes it is a young city, and I am a young artist. A frustration emerges; much like the mould, the artist also had to develop new skills by killing off his former desires and manipulating technology. My new series entitled HONG KONG surface project shows a new direction in my artistic research in which my technique becomes ever simpler, reducing the traces of pixelation until objects appear almost as they were found and photographed. Skyler and Bliss presents tectonic plates based on satellite images of the Arctic. Working in a hot and humid Hong Kong where mushrooms grow ferociously, a city artificially refrigerated by climate control, this series provides a conceptual image of a imaginary typographic map for survival. (Laurent Segretier
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Get PDFMultiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis
The socio-cultural milieux of the left in post-war Britain
Get PDFThis thesis examines the relationship between activist subjectivities and the shaping of Britain’s late
sixties extra-parliamentary left cultures. Based on the oral narratives of ninety men and women, it
traces the activist trajectory from child to adulthood to understand the social, psychological, and
cultural processes informing the political and personal transformation of young adults within the
new left cultures that emerged in the wake of Britain’s anti-war movement, the Vietnam Solidarity
Campaign (VSC). To this end the study charts the development of the political and cultural shifts on
the left over the decade from the early 1960s to the early 1970s. It shows how throughout this
period dialogue between inner and outer activist life occurred against a background of ongoing
realignment on the left from a fluid, eclectic cultural network around the VSC to a demarcated post-
VSC left after 1969, that saw increasing divergence between a non-aligned libertarian New Left on
the one hand and a Trotskyist far left milieu on the other.
The study seeks to claim a valid space for Britain’s left activist landscape within the political,
social and cultural framework of ‘1968’ and British post-war historiography. Privileging individual
and collective subjectivities, the thesis examines ways of belonging inside Trotskyist and non-aligned
left milieux by situating the respondents, their radical histories and activist cultures within the
changing post-war fabric. It shows that investigating individual and collective memories provides
deeper understanding of the ‘cognitive maps’ that young men and women created, as they
attempted to situate themselves as radical, global beings as well as local, gendered social citizens.
As micro-studies the individual stories reveal how the experience of social, emotional and
political maturation from child to adult intersected with a specific social and political moment – the
formation of a new and distinctive left culture that came to full fruition only in the aftermath of 1968
with the arrival of Women’s Liberation and the new personal politics. Exploring the social and
psychological impact of post-war childhood and youth, the study engages with the political and
emotional impact of Women’s Liberation on the men and women within the cultural context of the different left milieux.
Overall, the thesis questions how, from the mid-1960s to the early 1970s, the variant
cultures of the milieux penetrated public and private spaces, and shaped early life experiences of
work, political activity, family, and political and personal relations in order to understand how
activism shaped social patterns and psychic being
