35 research outputs found

    Modifikasi Fantom ORNL_MIRD untuk Kebutuhan Simulasi Monte Carlo Pasien Radioterapi Kanker Payudara Menggunakan MCNPX

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    In medical physics, the simulation of radiation dose distribution in the body of radiotherapy patients is generally carried out using the Monte Carlo method. But in conducting this simulation, medical physicists are often faced with the incompatibility problems of phantom geometry with simulation needs. Phantom ORNL-MIRD is the most commonly used phantom in simulation. In a radiotherapy simulation, cancer cells are usually only assumed to be in the phantom’s body without any concrete form. This can cause the administration of radiation doses that are not right on cancer cells. Phantom ORNL-MIRD is also only composed of three materials, namely bone, lung, and the rest are considered as soft tissue. This certainly provides inappropriate simulation results, especially in the case of breast cancer radiotherapy where the breast is composed of adipose tissue. This study aims to make ORNL_MIRD phantom modelling suitable for the needs of Monte Carlo simulations of breast cancer patients. The phantom modification will be carried out on the soft tissue structure of the breast and the structure of the skin tissue. Cancer cells with a diameter of 2 cm were also added to the left breast at a depth of 2.5 cm. The γ rays from radionuclide 60Co with the energy of 1.1732 MeV and 1.3325 MeV and the probabilities of 0.989 and 0.998, respectively, were exposed to the phantom. The simulation results show that there are significant differences before and after modification. Absorption dose values in the breast with a soft tissue without tumour cells were 0.31 mGy with a relative error of 0.0023, while the absorbency dose rate in the breast with soft tissue and tumour cells was 0.2 mGy with a relative error of 0.0023

    Microscopic online simulation for real-time traffic management

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    The thesis deals with the design and implementation of a distributed framework for real-time traffic management using microscopic online simulation.Trai

    Effluent filtration for more than particle removal

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    watermanagementCivil Engineering and Geoscience

    A role for SUMO modification in transcriptional repression and activation

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    Since the discovery of the SUMO (small ubiquitin-related modifier) family of proteins just over a decade ago, a plethora of substrates have been uncovered including many regulators of transcription. Conjugation of SUMO to target proteins has generally been considered as a repressive modification. However, there are now a growing number of examples where SUMOylation has been shown to activate transcription. Here, we discuss whether there is something intrinsically repressive about SUMOylation, or if the outcome of this modification in the context of transcription will prove to be largely substrate-dependent. We highlight some of the technical challenges that will be faced by attempting to answer this question

    Soitonopiskelijasta soitonopettajaksi : Näkökulmia kitaransoitonopettajuuteen

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    Opinnäytetyössä tarkastellaan kitaransoitonopettajan ammatillista kasvua ja oman työn kehittämistä. Lisäksi työ käsittelee kitaransoitonopettajan identiteetin muodostumista, työmotivaation ylläpitämistä, asiantuntijuuden rakentumista ja ammatillisten haasteiden kohtaamista. Työssä haastateltiin kolmea kokenutta kitaransoitonopettajaa heidän ammatti-identiteetistään, työmotivaatiostaan, asiantuntijuudestaan sekä siitä, mitä asioita he pitävät soitonopettajan työssä haasteellisina. Kitaransoitonopettajat kertoivat ammatti-identiteettinsä muodostuvan muusikko- ja soitonopettajaidentiteetistä. Lisäksi opettajat pitivät hyvän työmotivaation kannalta tärkeänä hyvän oppilas-opettaja-suhteen muodostumista sekä oppilaiden edistymistä opinnoissaan. Asiantuntijuus näytti vaikuttavan siihen, kuinka nopeasti soitonopettajat esimerkiksi kykenevät tekemään ratkaisuja opetustilanteessa. Suurin haaste näytti olevan eräänlainen genrerajojen rikkoutuminen soitonopetuksessa. Opinnäytetyö tuo esille kitaransoitonopetuksen mahdollisuuksia ja haasteita. Lisäksi se auttaa soitonopettajia ja soitonopettajiksi opiskelevia reflektoimaan omaa toimintaansa. Opinnäytetyön on myös tarkoitus auttaa soitonopettajia löytämään oikeanlainen tasapaino muusikkouden ja opettajuuden välillä.This thesis examines a guitar teacher’s professional growth and development of one’s own work. Moreover, the thesis discusses the development of a guitar teacher’s identity, maintenance of work motivation, formation of expertise and response to professional challenges. For the thesis, the author interviewed three experienced guitar teachers about their professional identity, work motivation, expertise and what they consider as challenges in instrumental teacher’s work. According to the guitar teachers, their professional identity consists of a musician’s and a teacher’s identity. Furthermore, the teachers thought that the formation of a good student-teacher relationship and seeing the students’ progress in their studies is an important factor in maintaining high work motivation. Expertise seemed to have an effect on how quickly the guitar teachers can find solutions in teaching situations. The biggest challenge seemed to be a kind of crossing over genre boundaries in instrumental teaching. The thesis discloses the possibilites and challenges of guitar teaching. In addition, it helps instrumental teachers and students studying to be instrumental teachers to reflect on their own actions. The purpose of this thesis is also to help instrumental teachers to find a balance between musicianship and teacher identity

    Graphic Design Business : Essentials to Focus Upon When Starting a One-Person Graphic Design Business

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    The purpose of this thesis is to seek to answer the question ‘What are the key elements to focus upon and keep in mind when starting a one-person graphic design business?’ The chosen method of research is a literature review combined with a case study implemented by the author, as a graphic designer seeking to successfully start their own design business. The literature review identified nine main headings, to answer the thesis question. The headings were as follows: company brand, legal papers and accountant, working environment, discipline and working habits, professionalism, communication, pricing, continual learning and networking, and personal side project. The ensuing case study, sought to implement these aspects that were identified in the literature review. The elements identified were found applicable and useful in the case study of starting and running a one-person graphic design business. It was concluded, that the nine headings resulting from the literature review – although others could be identified – serve as a helpful and important guide to focus upon when starting and running a successful one-person graphic design business

    Study of Potential Land Subsidence in East Aceh Region Based on Sediment Characterization Using Logging Data

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    Observations to determine subsidence potential were conducted in East Aceh, based on sediment characterization using logging data. The study encompassed 9 measurement sites representing 9 villages from 9 sub-districts. The data used obtained from the Aceh Energy and Mineral Resources Service (ESDM). This data is processed to obtain the resistivity value of the subsurface sediment layer. The measurement results were then depicted in 1D profile illustrating the cross-section of subsurface lithology for each measurement point. Subsequently, several measurement points were correlated to generate a 2D bottom image representing two regions, referred to as cross-section A-A' and cross-section B-B'. The correlation outcomes revealed that cross-sectional area A-A', spanning approximately ±50 km from east to west through Cot Geulumpang Village, Java Village, Kuala Lawah Village, Bukit Seroja Village, and Rantau Panjang Village, shows a shallow surface layer consisting mostly of sand and sandy clay soil. The sand layer in this area exhibited a medium to fine size with a configuration of round-shaped particles containing quartz and shell minerals, forming a soft sediment layer. The structure and type of sediment in this area indicate the potential for land subsidence

    Open data barometer global report

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    Highlights the lack of open and accessible data on the performance of key public services. If the political and social impacts of open data are to be realised, work to increase the supply of datasets from right across government will be needed, alongside sustained investment in capacity building, training and support for effective data use. Introduction The core idea behind Open Government Data (OGD) is a simple one: public data should be a shared resource. Making data open is valuable not only for the government departments that collect and release the data, but also for citizens, entrepreneurs and other parts of the public sector. The implementation of OGD takes dedicated and sustained policy attention. Affecting widespread impact through the release of OGD relies not only upon the supply of high-quality data, but also upon the capacity of users to work with the data, and the ability of government to engage proactively with those users. In our complex world, access to OGD has the power to secure enhanced government accountability, empower coordinated action to improve public services and civil society, and inspire new business ideas. Yet far too often, access to data, along with the skills to understand and make use of it, are distributed unequally, and would-be users frequently encounter unnecessary technical and legal restrictions that prevent data re-use. Calls for a “Data Revolution” — led by the United Nations — have placed renewed attention on ensuring the collection and management of high-quality data around the world through strengthened statistical capacity, and are driving a focus on the use of new “big data” resources in policy making. Against this backdrop, questions concerning who has access to data, and whether citizens have the capability and freedoms to create, access, and analyse data about their own communities and concerns, become ever more important for securing a fair balance of power in our societies
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