198,732 research outputs found
Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels
No full textRecent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy to a potent anxiolytic inhibiting voltage dependent calcium channels (VOCCs) as highly selective drug target. In contrast to previous publications where exorbitant high concentrations were used, the effects of lavender oil in behavioral, biochemical, and electrophysiological experiments were investigated in physiological concentrations in the nanomolar range, which correlate to a single dosage of 80 mg/d in humans that was used in clinical trials. We show for the first time that lavender oil bears some similarities with the established anxiolytic pregabalin. Lavender oil inhibits VOCCs in synaptosomes, primary hippocampal neurons and stably overexpressing cell lines in the same range such as pregabalin. Interestingly, Silexan does not primarily bind to P/Q type calcium channels such as pregabalin and does not interact with the binding site of pregabalin, the α2δ subunit of VOCCs. Lavender oil reduces non-selectively the calcium influx through several different types of VOCCs such as the N-type, P/Q-type and T-type VOCCs. In the hippocampus, one brain region important for anxiety disorders, we show that inhibition by lavender oil is mainly mediated via N-type and P/Q-type VOCCs. Taken together, we provide a pharmacological and molecular rationale for the clinical use of the oral application of lavender oil in patients suffering from anxiety
Inhaled Lavender Effect on Anxiety and Pain Caused From Intrauterine Device Insertion
No full textIntroduction: Intrauterine device (IUD) is the most common reliable, effective and reversible contraceptive method used worldwide and in areas with high growth rate is of particular importance. IUD insertion is associated with high anxiety in most people that causes pain and discomfort. The aim of this study was to determine the effects of aromatherapy on anxiety and pain caused by IUD insertion. Methods: This study was conducted on 106 women in a health care center located in Ardebil, Iran. Participants were divided into two groups by randomized blocks of 4 and 6. In the experimental group lavender scent was inhaled and in the control group the placebo was inhaled 30 minutes before IUD insertion. The anxiety of the participants was measured by Spielberger questionnaire, and the pain of IUD insertion was measured immediately after the insertion using visual analog scale (range 0-10). Results: The mean score (standard deviation) of anxiety before intervention was 43.2 (9.2) in the experimental group that decreased after intervention to 39.0 (10.5) (p < 0.001), while this score was 42.2 (9.0) and 41.5 (8.4) before and after the intervention in the control group (p = 0.21). Mean differences of anxiety in both groups was statistically significant (p < 0.001). The pain score after intervention did not show significant difference between two groups (p = 0.51). Conclusion: Aromatherapy with lavender inhalation was effective in decreasing anxiety in IUD procedure, and this method can be used in health care centers as complementary treatments
Interview with George W. Lavender
No full textGeorge Lavender joined the U.S. Navy in 1943 and attended boot camp at Great Lakes, Illinois. He served with a Naval Medical Corps with the 16th Antiaircraft Artillery Battalion and the 5th Separate Medical Company. Lavender's military campaigns included American Samoa and Funafiti Island
Lavender oil as an ecofrindly inhibitor for mild steel in 1 M HCl
No full textLavender oil is extracted from lavender herb, collected in the east region of Morocco (Tafoughalt) and tested as corrosion inhibitor for mild steel in 1 M HCl. The inhibiting effect was studied by weight loss measurements, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) methods. Polarisation measurements show that lavender oil essentially acts as a cathodic inhibitor. The natural oil reduced the overall corrosion current density. The protection efficiency was found to increase with oil content to obtain ca. 90% at only 2 g L-1 and kept its inhibiting efficiency the same even at higher temperatures. The adsorption of lavender oil on mild steel followed the Langmuir's isotherm model. The thermodynamic parameters for inhibiting process were calculated and interpretation of the results was given
Lavender-Like Ga-Doped Pt<sub>3</sub>Co Nanowires for Highly Stable and Active Electrocatalysis
No full textOne-dimensional
(1D) PtM (M = Fe, Co, Ni) nanowires (NWs), which
represent a thriving class of electrocatalysts for fuel cells, are
experiencing a restriction in long-term durability because of the
dissolving issue related to transition metals. Utilizing one-dimensional
Pt3Co NWs as the basic catalyst model, here we have successfully
demonstrated significant improvements in electrocatalytic durability
and activity derived from doping of Ga atoms. The optimized surface
energy caused by the doping of Ga atoms drives the resulting catalysts
to exhibit good durability for oxygen reduction reaction (ORR) electrocatalysis.
However, although oxygen binding energy (EO) would rather deviate from the optimal value because of excessive
Ga on the surface, the formation of proper Ga–O bonding can
also promote oxygen binding to approach an optimal value, which results
in an enhanced ORR activity. It can be therefore concluded that doping
of an appropriate amount of Ga atoms has a positive effect in improving
the ORR performance of the catalyst, not only in terms of specific
activity but also in durability. This interesting phenomenon was also
further extended to improve the catalysis of methanol oxidation (MOR)
and ethanol oxidation (EOR) reactions, thus reflecting multifunctionalities
of lavender-like Ga-doped Pt3Co NWs on fuel cell reactions.
This study highlights the great potential of Ga-doped strategies for
surface and near-surface regulation, which can effectively address
the poor durability of 1D Pt-based NWs for energy catalytic technology
Lavender and the Nervous System
No full textLavender is traditionally alleged to have a variety of therapeutic and curative properties, ranging from inducing relaxation to treating parasitic infections, burns, insect bites, and spasm. There is growing evidence suggesting that lavender oil may be an effective medicament in treatment of several neurological disorders. Several animal and human investigations suggest anxiolytic, mood stabilizer, sedative, analgesic, and anticonvulsive and neuroprotective properties for lavender. These studies raised the possibility of revival of lavender therapeutic efficacy in neurological disorders. In this paper, a survey on current experimental and clinical state of knowledge about the effect of lavender on the nervous system is given
Program: Featured Lecture, Redemptive Spirituality (What God Intended in Creation).
No full textProgram for the Thirty-First Annual William M. Green Distinguished Christian Lecture Program with featured lecturer Dr. Earl Lavender, Executive Director at the Institute for Christian Spirituality, Lipscomb University
Literary Afrofuturism in the Twenty-First Century
No full textPart one: Afrofuturism now. Author roundtable on Afrofuturism / Isiah Lavender III and Lisa Yaszek -- Dangerous muses: black women writers creating at the forefront of Afrofuturism / Sheree R. Thomas -- Part two: Afrofuturism in literary history. This time for Africa! Afrofuturism as alternate (American) history / De Witt Douglas Kilgore -- Middle age, mer people, and the Middle Passage: Nalo Hopkinson's Afrofuturist journeying in The new moon's arms / Gina Wisker -- Young adult Afrofuturism / Rebecca Holden -- Part three: Afrofuturism in cultural history. Space/race: recovering John M. Faucette / Mark Bould -- Runoff: Afroaquanauts in landscapes of sacrifice / Elizabeth A. Wheeler -- Black futures matter: Afrofuturism and geontology in N.K. Jemisin's Broken Earth trilogy / Lisa Dowdall -- Part four: Afrofuturism and Africa. We are terror itself: Wakanda as nation / Gerry Canavan -- Global Afrofuturist ecologies / Jerome Winter -- "You can't go home again": Deji Bryce Olukotun's Nigerians in space, science fiction, and global interdependence / Marleen S. Barr -- Faster than before: science fiction in Amos Tutuola's The palm-wine drinkard / Nedine Moonsamy -- Coda: Wokeness and Afrofuturism / Isiah Lavender III and Lisa Yaszek.Item embargoed for five year
A critical ethnography of young adolescents' occupational choices in a community in post-apartheid South Africa
No full textThis thesis explored the occupational choices of young adolescents in a southern peninsula Cape Town community of Lavender Hill in South Africa. Informed by current research and prior professional and personal experiences with young adolescents in Lavender Hill, the research question asked: 'What informs occupational choice among young adolescents in Lavender Hill?' This complemented the research aim, which was to generate insight into the nature of the occupational choices of a group of young adolescents in Lavender Hill, and the factors that influenced their occupational choices
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