45,635 research outputs found
The effect of polystyrene sodium sulfonate grafting on polyethylene terephthalate artificial ligaments on in vitro mineralisation and in vivo bone tissue integration
No full textThis study investigates the impact of polystyrene sodium sulfonate (PolyNaSS) grafting onto the osseointegration of a polyethylene terephthalate artificial ligament (Ligament Advanced Reinforcement System, LARS ) used for Anterior Cruciate Ligament (ACL). The performance of grafted and non-grafted ligaments was assessed in vitro by culturing human osteoblasts under osteogenic induction and this demonstrated that the surface modification was capable of up-regulating the secretion of ALP and induced higher level of mineralisation as measured 6 weeks post-seeding by Micro-Computed Tomography. Grafted and non-grafted LARS were subsequently implanted in an ovine model for ACL reconstruction and the ligament-to-bone interface was evaluated by histology and biomechanical testings 3 and 12 months post-implantation. The grafted ligaments exhibited more frequent direct ligament-tobone contact and bone formation in the core of the ligament at the later time point than the nongrafted specimens, the grafting also significantly reduced thefibrous encapsulation of the ligament 12 months post-implantation. However, this improved osseo-integration was not translated into a significant increase in the biomechanical pull-out loads. These results provide evidences that PolyNaSS grafting improved the osseo-integration of the artificial ligament within the bone tunnels. This might positively influence the outcome of the surgical reconstructions, as higher ligament stability is believed to limit micro-movement and therefore permits earlier and enhanced healing.Programme ANR LIGAR
Cololejeunea sublatistyla Jian Wang
No full textCololejeunea sublatistyla Jian Wang bis et R. L.Zhu, Phytotaxa 161 (2): 165, 2014 (see Wang et al. 2014a). TYPE: “ CHINA. Hainan. Ledong Co., Jianfengling National Nature Reserve, epiphyllous, 812 m, 19 Jul. 2009, Ling-Yan Zhou 0323085 (holotype: HSNU!)”.Published as part of Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2016, Early Land Plants Today: Index of Liverworts & Hornworts 2013 - 2014, pp. 133-185 in Phytotaxa 269 (3) on page 139, DOI: 10.11646/phytotaxa.269.3.1, http://zenodo.org/record/477969
Acrolejeunea crassicaulis Jian Wang
No full textAcrolejeunea crassicaulis (Steph.) Jian Wang bis et Gradst., Bryophyte Diversity Evol. 36 (1): 38, 2014 (see Wang et al. 2014c). BASIONYM: Hygrolejeunea crassicaulis Steph., Sp. Hepat. (Stephani) 5: 550, 1914 (see Stephani 1914).Published as part of Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2016, Early Land Plants Today: Index of Liverworts & Hornworts 2013 - 2014, pp. 133-185 in Phytotaxa 269 (3) on page 135, DOI: 10.11646/phytotaxa.269.3.1, http://zenodo.org/record/477969
A Study of the Classical Landscape at the Wang River Villa of Wang Wei
No full textThe landscape of Wang Wei's Wang River Villa is examined by reviewing the essays and papers written about the poetical collaboration, the “Wang River Collection.” The purpose of this paper is to clarify the meaning of villa architecture in China. The author expects that this research will contribute to a mutual understanding between cultures. The villa was a Utopia for Wang. On the other hand, he was a pious Buddhist and Buddhistic concepts are reflected in the landscape. I consider the features of the classical landscape of Xie Lingyun and "Chu Ci," as written in “The Collection,” a reflection of the Buddhistic concept. When considering what the classics meant to Wang Wei, it is apparent that his villa is a representation of the classical landscape. It is not an imitation of the classical landscape, but a unique and original creation of art by Wang.departmental bulletin pape
Acrolejeunea sinensis (Jian Wang bis, R.L.Zhu et Gradst.) Jian Wang bis et Gradst.
No full textAcrolejeunea sinensis (Jian Wang bis, R.L.Zhu et Gradst.) Jian Wang bis et Gradst., Bryophyte Diversity Evol. 36 (1): 39, 2014 (see Wang et al. 2014c). BASIONYM: Trocholejeunea sinensis Jian Wang bis, R.L.Zhu et Gradst., Phytotaxa 174 (5): 296, 2014 (see Wang et al. 2014b).Published as part of Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2016, Early Land Plants Today: Index of Liverworts & Hornworts 2013 - 2014, pp. 133-185 in Phytotaxa 269 (3) on page 135, DOI: 10.11646/phytotaxa.269.3.1, http://zenodo.org/record/477969
Acrolejeunea (sect. Trocholejeunea) Jian Wang
No full textAcrolejeunea sect. Trocholejeunea (Schiffn.) Jian Wang bis et Gradst., Bryophyte Diversity Evol. 36 (1): 38, 2014 (see Wang et al. 2014c). BASIONYM: Trocholejeunea Schiffn., Ann. Bryol. 5: 160, 1932 (see Dixon et al. 1932).Published as part of Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2016, Early Land Plants Today: Index of Liverworts & Hornworts 2013 - 2014, pp. 133-185 in Phytotaxa 269 (3) on page 135, DOI: 10.11646/phytotaxa.269.3.1, http://zenodo.org/record/477969
Biological and Biomechanical Evaluation of the Ligament Advanced Reinforcement System (LARS AC) in a Sheep Model of Anterior Cruciate Ligament Replacement: A 3-Month and 12-Month Study
No full textPurposeThe purposes of this study were to assess tissue ingrowth within the Ligament Advanced Reinforcement System (LARS) artificial ligament (LARS AC; LARS, Arc sur Tille, France) and to study the biomechanical characteristics of the reconstructed knees in a sheep model of anterior cruciate ligament (ACL) replacement.MethodsTwenty-five female sheep underwent excision of the proximal third of the left ACL and intra-articular joint stabilization with a 44-strand polyethylene terephthalate ligament (mean ultimate tensile failure load, 2,500 N). Animals were killed either 3 or 12 months after surgery. Explanted knees were processed for histology (n = 10) or mechanical tests including tests of laxity and loading to failure in tension (n = 15).ResultsWell-vascularized tissue ingrowth within the artificial ligament was only observed in the portions of the ligament in contact with the host's tissues (native ligament and bone tunnels). Ligament wear was observed in 40% of explanted knees. The ultimate tensile failure loads of the operated knees at both time points were inferior to those of the contralateral, intact knees (144 ± 69 N at 3 months and 260 ± 126 N at 12 months versus 1,241 ± 270 N and 1,218 ± 189 N, respectively) (P < .01). In specimens with intact artificial ligaments, failure occurred by slippage from the bone tunnels in all specimens explanted 3 months postoperatively and in half of the specimens explanted 12 months postoperatively.ConclusionsThis study provides evidence that the LARS AC has a satisfactory biointegration but that it is not suitable for ACL replacement if uniform tissue ingrowth is contemplated. Despite good clinical performance up to 1 year after implantation, none of the reconstructions approached the mechanical performance of the normal ACL in the ovine model. Partial tearing of the artificial ligament, which led to a significant decrease in ultimate tensile strength, was observed in 40% of cases in the ovine model.Clinical RelevanceThe LARS is not a suitable scaffold for ACL replacement. Further animal studies are needed to evaluate its potential for augmentation of ligament repair.Agence Nationale pour la Recherche (ANR), France [Grant LIGART 06-TECSAN-006-01
First person – Yihua Wang
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Yihua Wang is the first author on ‘Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively’, published in Journal of Cell Science. Yihua is a Lecturer in Biological Sciences at the University of Southampton, studying cell signalling in lung fibrosis and cancer, drug target validation and gene function analysis
Trocholejeunea sinensis Jian Wang
No full textTrocholejeunea sinensis Jian Wang bis, R.L.Zhu et Gradst., Phytotaxa 174 (5): 296, 2014 (see Wang et al. 2014b). TYPE: “ CHINA. Guangxi. Jinxiu Co., Dayaoshan National Nature Reserve, Cathaya argyrophylla Protection Station, on rotten logs, 900–1000 m, 19 Jul. 2009, Wen Ye & Yu-Mei Wei 20090719-47 A (holotype: HSNU!)”.Published as part of Söderström, Lars, Hagborg, Anders & Konrat, Matt Von, 2016, Early Land Plants Today: Index of Liverworts & Hornworts 2013 - 2014, pp. 133-185 in Phytotaxa 269 (3) on page 168, DOI: 10.11646/phytotaxa.269.3.1, http://zenodo.org/record/477969
Supporting the research process through expanded library data services
No full textPurpose – The purpose of this paper is to describe how the authors gained a better understanding of the variety of library users' data needs, and how gradually some new data services were established based on current capabilities.Design/methodology/approach – This paper uses a case study of the new data services at the John Cotton Dana Library, at Rutgers, The State University of New Jersey, Newark campus, to demonstrate the possible ways to extend data reference services and provide data computing services. A content analysis of services records shows how each user group falls into the multiple data services levels and subcategories.Findings – Library users can be classified into many different categories, and each of these may have different needs. Research centers might have big projects involving data gathering and applications where a librarian can mainly provide consultation; while an individual faculty member or student might need the librarians as research partners, with help for their specific problems. Computing data services can involve group training and statistical analysis assistance, where researchers need emergent help. Data librarians can take various opportunities for data management education, thereby gradually raising awareness and cultivating better research habits among researchers.Originality/value – Library data computing services can make unique contributions to faculty and students' research and study. Institution, library and users' interaction determines the levels and extent of data services and is generalized from the description and analysis of typical data service examples. Classic concept of data services levels is applied to a concrete case of data services program, and sub-categories of each data services level and user types are developed based on the authors' services record.This article is (c) Emerald Group Publishing and permission has been granted for this version to appear here at the RUcore: Rutgers University Community Repository . Emerald does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Emerald Group Publishing Limited.Peer reviewe
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