2,438 research outputs found
Utility of novel diagnostic tests for tuberculosis using human urine
No full textIncludes abstract.Includes bibliographical references.Two thirds of new TB cases in sub-Saharan Africa are HIV coinfected. HIV-TB co-infection increases the incidence of extra-pulmonary, sputum smear-negative and sputum-scarce TB. In these vulnerable patientgroups with high mortality rates, sputum-based diagnostic tools are unhelpful. Urine-based diagnostics offer an attractive, easily available alternative for rapid diagnosis. We evaluated the point-of-care urine LAM strip test (Determine TB LAM Ag test, Alere) and urine-based Xpert MTB/RIF for TB diagnosis in two patient cohorts with high HIV prevalence. A spot urine sample was collected from two cohorts of persons with suspected TB. The first cohort consisted of ambulatory primary care clinic patients suspected of having TB (group 1) whilst the second comprised hospitalised patients with suspected HIV co-infection (group 2). The urine LAM ELISA, LAM strip test and Xpert MTB/RIF were performed according to the manufacturer’s instructions. In addition, the effects of using an alternative ‘rulein’ cut-point for the urine LAM strip test and a pelleted (2-10ml) urine sample for Xpert MTB/RIF testing on diagnostic accuracy and inter-reader reliability was assessed. The diagnostic reference standard was M. tuberculosis culture positivity
Turbulent drag reduction by hydrophobic surfaces with shear-dependent slip length
No full textThe stabilisation of a parabolic equilibrium profile in a three-dimensional (3D) turbulent channel flow for an incompressible fluid is addressed with the objective of achieving drag reduction. The formulation of this problem stems from Balogh’s work [1] where Lyapunov stability analysis was used to devise prototype feedback laws and prove global stability of the solutions. This treatment only considers the controller as a mathematical artefact, but it can actually be linked to physical control strategies modelling hydrophobic surfaces and porous media. In the former, only linear slip velocity boundary conditions (BC) were considered [8]. However, experiments [2] have suggested that the slip length may be shear-dependent. Motivated by these, the effect on drag reduction of a shear-dependent slip length surface is examined in the present study using Direct Numerical Simulations (DNS) at Re τ0 = u τ0 δ/ν ≃ 180. δ is the channel half height, u τ0 the wall-shear velocity for regular no-slip walls channel and ν the kinematic viscosity. The theoretical analysis in [5], is extended to this new model. The proposed formulation shows that the skin-friction coefficient can be reduced by tuning the parameters in the shear-dependent slip length model. The results, which verified by DNS simulations, show that by taking a slip length value based on a constant slip model [8] and combining it within a shear-dependent model, up to 50% drag reduction can be obtained. The effect of control is further assessed by formulating the Fukagata identity [4] with general boundaries; the weighted Reynolds shear-stress for each quadrant shows an enhanced reduction in the sweep/ejection events compared to the constant slip model
Pengintegrasian Perencanaan Sumberdaya Manusia Dan Strategi Organisasional : Catatan Kecil
No full textThis study is short review and critical note of author on the article integrating HR planning and organizational strategy written Simon S.K. Lam & John Schaubroeck (1998). The author has discussed and written critical note related concepts, practices and methods on their article. Note in this article explained that the integration of human resources planning and organizational strategy play an important role in explaining organizational performance, but contextual aspects should be considered
Hydrodynamical turbulence by fractal fourier decimation
No full textWe present a systematic numerical investigation of high-resolution 3D isotropic and homogeneous turbulence resolved on a decimated set of Fourier modes. Fractal decimation acts to decrease the effective dimensionality of the flow by allowing triadic interactions only in a set of Fourier modes N(k) proportional to k^DF for large k. While keeping the symmetries of the original 3D Navier-Stokes equations unchanged, a dramatic change in small-scale statistics is detected at decreasing the fractal dimension DF . Already at fractal dimension DF = 2.8, a global self-similar behaviour is observed in the inertial range of scales, the consequence of such transition are the restoration of the scaling symmetry and vorticity distribution that becomes close to Gaussian. We relate the results to the different roles of local vs non-local interactions in the energy transfer range
Chinese literary works translated into Baba Malay: a bibliographical study
No full textAnalyses 68 unique titles of Baba translated works published between 1889 and 1950. The titles are held in the libraries of the University of Malaya (UM), Science University Malaysia (USM), National University of Malaysia (UKM), the Dewan Bahasa dan Pustaka (DBP), National University of Singapore (NUS), National Library of Singapore (NLS) and the British Library (BL). The results reveal three periods of active publication of Baba translated works. A total of 18 works were translated before World War I, followed by 10 just after the war, 39 titles were published before the break of the World War II and 1 was identified in 1950. There were 103 persons involved in the 68 translated works, some of whom are responsible for more than one title. The most prominent translators were Chan Kim Boon, Wan Boon Seng, Seow Chin San and Lee Seng Poh. Some of the translators were also be editors, illustrators or editors. There were 31 publishers and 21 printing presses involved, all were located in Singapore. The most active publishers were Wan Boon Seng, Kim Seck Chy Press and Nanyang Romanised Malay Book Co. The translated works mainly cover historical classical Chinese stories, chivalrous stories, romances, folklore and legends. The titles were priced between 10 cents to 2 dollars in Straits currency. The University of Malaya Library held the largest number of unique title (62) out of which 15 were unique titles
Avaliação da atividade antiviral de extratos nebulizados de Achyrocline satureioides(LAM.) DC.,Asteraceae - marcela
No full textLeast Squares Fitting of Chacón-Gielis Curves by the Particle Swarm Method of Optimization
No full textRicardo Chacón generalized Johan Gielis's superformula by introducing elliptic functions in place of trigonometric functions. In this paper an attempt has been made to fit the Chacón-Gielis curves (modified by various functions) to simulated data by the least squares principle. Estimation has been done by the Particle Swarm (PS) methods of global optimization. The Repulsive Particle Swarm optimization algorithm has been used. It has been found that although the curve-fitting exercise may be satisfactory, a lack of uniqueness of Chacón-Gielis parameters to data (from which they are estimated) poses an insurmountable difficulty to interpretation of findings.Least squares multimodal nonlinear curve-fitting; Ricardo Chacón; Jacobian Elliptic functions; Weierstrass ; Gielis super-formula; supershapes; Particle Swarm method; Repulsive Particle Swarm method of Global optimization; nonlinear programming; multiple sub-optima; global; local optima; fit; empirical; estimation; cellular automata; fractals
The Straits Chinese contributions to Malaysian literary heritage: focus on Chinese stories translated into Baba Malay
No full textThe Chinese born in the Straits Settlements of Peninsula Malaya (Penang, Singapore, Malacca) are called Babas to distinguish them from those born in China. The Babas are rooted from three different races, Chinese, Malay and English and as such their lifestyles show a mixed blend of the Chinese, Malay and European cultures. Because of this cultural background, the Babas exhibited a unique cultural mix in the clothes they wear, their culinary skills, architectural styles, language and literature. The paper describes the characteristics of 68 Baba translated works published between 1889 and 1950; focusing on the publication trends between the period under study, the persons involved in the creative output, the publishers and printers involved, the contents of the translated works, the physical make-up of the works and the libraries where these works are held
Achievements in medicine 1985-1995
No full textpublished_or_final_versionForeword Wang Gungwu Wang, Gungwu vUniversity's Mission Statement viiiMission and Objectives of the Department of Medicine ixPreface Y.L. Yu Yu, Y. L. xiSubspecialty Divisions and the General Practice UnitAppendix Staff List 171Vision and Mission - a History of the Department of Medicine Rosie T.T. Young Young, Rosie, T. T. 1The Department of Medicine: Today and Tomorrow S.K. Lam Lam, S. K. 14Professor Chan Tai-kwong - a Personal Tribute David Todd Todd, David 21Curriculum Vitae of Professor Chan Tai-kwong 25Cardiology C.P. Lau, K.L. Cheung, W.H. Chow and David S.W. Ho Lau, C. P. Cheung, K. L. Chow, W. H. Ho, David, S. W. 37Clinical Pharmacology Cyrus R. Kumana and Bernard M.Y. Cheung Kumana, Cyrus R. Cheung, Bernard, M. Y. 55Endocrinology Karen S.L. Lam and Annie W.C. Kung Lam, Karen, S. L. Kung, Annie, W. C. 62Gastroenterology and Hepatology S.K. Lam, C.L. Lai, C.K. Ching and Benjamin C.Y. Wong Lam, S. K. Lai, C. L. Ching, C. K. Wong, Benjamin, C. Y. 74General Practice Unit Anthony S. Dixon and Cindy L.K. Lam Dixon, Anthony S. Lam, Cindy, L. K. 91Geriatric Medicine L.W. Chu Chu, L. W. 101Haematology and Oncology Raymond H.S. Liang Liang, Raymond, H. S. 103Molecular Medicine Vivian N.Y. Chan Chan, Vivian, N. Y. 125Nephrology Ignatius K.P. Cheng and Daniel T.M. Chan Cheng, Ignatius, K. P. Chan, Daniel, T. M. 132Neurology Y.L. Yu, Jason K.Y. Fong and S.L. Ho Yu, Y. L. Fong, Jason, K. Y. Ho, S. L. 143Respiratory Medicine W.K. Lam, Mary S.M. Ip and Jane C.K. Chan Lam, W. K. Ip, Mary, S. M. Chan, Jane, C. K. 153Rheumatology C.S. Lau and Raymond W.S. Wong Lau, C. S. Wong, Raymond, W. S. 16
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