43 research outputs found
Effective field theory for vector-like leptons and its collider signals
No full textWe argue that in models with several high scales; e.g. in composite Higgs models or in gauge extensions of the Standard Model (SM), vector-like leptons can be likely produced in a relatively large root s region of the phase space. Likewise, they can easily decay into final states not containing SM gauge bosons. This contrasts with the topology in which these new particles are being searched for at the LHC. Adopting an effective field theory approach, we show that searches for excited leptons must be used instead to test this scenario. We derive bounds on all the relevant interactions of dimension six; the most constrained ones being of about 0.05 TeV-2. We build new observables to improve current analyses and study the impact on all single-field UV completions of the SM extended with a vector-like lepton that can be captured by the effective field theory at tree level, in the current and in the high-luminosity phase of the LHC. (C) 2020 The Author(s). Published by Elsevier B.V
The Essence of Man’s Future as a Personal Choice of the Individual
No full textThis article analyzes nature and possibility of determining a man of future. The basis learned in the article can serve as a basis of the question of human nature. An author emphasizes that the question of a person’s future stems from the philosophy of education and can be learned on the basis of philosophical anthropology. Representatives of the last one, as the author notes, for a long time have been studying the nature of man, trying to synthesize knowledge of different sciences. It is noted that the main feature of the human being is to be able to make mindful choice and to take responsibility for its consequences. The article illustrates the capabilities of a normal choice for future generations. The works of the classical representatives of German philosophical and anthropological school, and the ideas of Kiev school of philosophy, as well as the documents of a general importance as the Declaration of Independence served as the materials of the research woer. The work itself is based on the principle of reflection upon the general theses. This paper learns the main ideas of human nature and analyses the impact of law on the provision of human capabilities and the choice in common. The suggestion is made of the necessity of emotions, feelings and sensations as the basis of human choice. The author concludes that the main task of philosophy of education is to preserve and ensure the man of future to make its mindful choise.The choice that is based on the rational thinking as well as on the emotional impuls
Чи стануть креативні індустрії драйверами економічного зростання в Україні?
No full textThe article answers the question whether creative industries can become the drivers of the country’s economic development The article defines the creative economy and creative industries. The paper shows how the creative economy and innovative economy differ. The basis of the creative economy is culture, and the basis of the innovative economy is technology. The author shows the imperfection of the classification of creative industries in Ukraine. For example, computer equipment is counted together with the software. However, computer equipment (hardware) is an innovative technology, and software is a creative industry. This situation leads to errors in calculating the contribution of creative industries to the GDP of the country. The article contains a comparative analysis of the contribution of creative industries to the economy of OECD countries, the UK and Ukraine. The article presents examples of creative clusters in Ukraine. In addition, it has been shown that most of the creative industries in Ukraine are in the informal economy, and they are not reflected in official statistics.The article draws attention to the peculiarities of the state policy on increasing the share of creative industries in the economy, as well as indicators for assessing the contribution of creative industries to the country’s economic development. The article shows that productivity and growth rates in different sectors of creative industries are different. This is illustrated by the example of two polar sectors: IT and handmade. IT and handmade relate to creative industries and form a creative economy; however, productivity, growth, and return on investments in these sectors are significantly different. So the author concludes that the share of creative economy in different countries is up to 6 %. The drivers of economic development can become creative industries with high rates of growth and profitability, namely IT, the development of video games, and scientific developments.Article received 30.04.2018Статтю присвячено пошуку відповіді на запитання: чи можуть креативні індустрії стати драйверами економічного розвитку країни? Визначено категоріальний апарат, зокрема розглянуто поняття креативної економіки, показано її відмінність від інноваційної економіки. Крім того, у статті описано недосконалість класифікації креативних індустрій в Україні, наприклад, у статистиці комп’ютерне обладнання обраховують разом із програмним забезпеченням, через що спостерігається незіставність офіційних статистичних даних із фактичною ситуацією. Зроблено порівняльний аналіз внеску креативних індустрій в економіку Великої Британії, країн ОЕСР та України. У статті наведено приклади осередків креативної економіки в Україні. Крім того, визначено показники для оцінки внеску креативних індустрій в економічний розвиток країни та зазначено особливості державної політики щодо підвищення їх частки в економіці. Також поставлено дискусійне питання щодо продуктивності креативних індустрій, зокрема показано, що ІТ-сектор та «хенд мейд» належать до креативних індустрій, формують креативну економіку, але за продуктивністю, рівнем зростання та окупності інвестицій суттєво відрізняються. Зроблено висновок, що частка креативних індустрій в економіках різних країн є невеликою, до 6 %, драйверами економічного розвитку можуть стати креативні індустрії з високими темпами зростання та дохідності (ІТ-сектор, розробка відеоігр, наукові розробки тощо).Матеріал надійшов 30.04.201
Розвиток мовленнєво-комунікативної культури майбутніх учителів початкових класів в умовах реформування освіти
No full textIn the article the author analyzes the main ways and means of improving speech and communication culture of primary school teachers. Materials of the article is covering one of the urgent problems of training future teachers – the development of speech-communicative culture of primary school teachers in the conditions of reforming of education. The article provides an analysis of the General linguistic situation of the country. Highlights the problem of forming speech and communication culture of future primary school teachers and are recognized as the basic ways and means for its improvement. The publication presents an analysis of the category of «speech culture» as a linguistic and social and educational phenomenon, reveals conceptual framework and technology of its development of future teachers during training in higher education. To increase the development speech and communication culture of primary school teachers the paper proposes a number of measures, among which we determine the most effective. The attention is paid to formation and development of cognitive motives that influence the knowledge and skills of students in accordance with their future profession. It is described how to monitor the development speech and communication culture of future primary school teachers. The proposed method of development management speech and communication culture of future primary school teachers, thereby improving their speech and communication culture, the main tasks of professional training. The problems that require further study are described.
Key words: speech-communicative culture, language issue, future primary school teachers, culture of speech, slang, linguistic personality, speech culture, Ukrainian literary language, reform, language education, vocabulary, knowledge of students.У статті автором здійснено аналіз основних шляхів і засобів покращення мовленнєво-комунікативної культури майбутніх учителів початкових класів. Матеріали статті висвітлюють одну з актуальних проблем підготовки майбутніх педагогів – розвиток мовленнєво-комунікативної культури майбутніх учителів початкових класів в умовах реформування освіти. Висвітлюється проблема формування мовленнєво-комунікативної культури у майбутніх учителів початкової школи та визнаються основні шляхи і засоби щодо її удосконалення. У публікації представлено аналіз категорії «мовленнєва культура» як лінгвістичного і соціопедагогічного феномена, розкрито концептуальні засади та технології її розвитку у майбутніх учителів під час навчання у вищому навчальному закладі. Для підвищення розвитку мовленнєво-комунікативної культури майбутніх учителів початкових класів у статті пропонується ряд заходів, серед яких визначаються найбільш дієві. Приділяється увага формуванню й розвитку пізнавальних мотивів, що впливають на знання й уміння студентів відповідно до їх майбутньої професії.
Ключові слова: мовленнєво-комунікативна культура, мовне питання, майбутні учителі початкових класів, культура мовлення, сленг, мовна особистість, мовленнєва культура, українська літературна мова, реформа, мовна освіта, лексика, знання студентів
Abstract P2-12-11: Does conservative surgery treatment for locally advanced breast cancer safe after neoadjuvant treatment?
No full textAbstract
BACKGROUND:
The aim of this study was to assess the oncological efficacy of breast conserving surgery (BCS) after neoadjuvant chemotherapy in patients with local advanced breast cancer.
PATIENTS AND METHODS:
A retrospective cohort study was conducted with locally advanced breast cancer invasive (Stage IIb to III) treated at ICESP, an oncologic referral center between 2008 and 2016. Endpoints were disease free survival (DFS), local disease free survival (LDFS) and overall survival (OS). Multivariable analyses were performed using Cox proportional hazards models.
RESULTS:
530 patients were included, 26% (138) were stage IIB, 41.9% (222) IIIA, 29.6% (157) IIIB and 2.5% (13) IIIA. 88.8% (470) were invasive ductal carcinoma. The mean age was 51.5(23-95). 95.5% and 4.5% were submitted Neoadjuvant Chemotherapy and Hormone therapy, respectively. The BCS were performed in 24.5% (130) patients versus 75.5% (400) of mastectomies. The mean follow up was 36.4(0.16-80.2) months. There were no differences in local disease free-survival 59 (95%CI 58-61) versus 60 (95%CI 57-60); p=0.4 and overall survival 56.2 (95%CI 52-60) versus 59.3(95%CI 53-65); p= 0.24 for mastectomy and BCS. The disease free survival was lower at mastectomy group 51.4 (95%CI 49-53) versus 56,8 (95%CI 53-59); p=0.01. Logistic regression models were significant only for cancer stage both patterns, although the results were better for masses, particularly when kinetic assessments were included (LR 12.8; p = 0.005)
CONCLUSION:
In our population, the BCS does not affect the overall and local disease-free survival rates, which seems to be safe to perform in patients who desire to conserve the breast after neoadjuvant treatment.
Citation Format: Boufelli G, Mota BS, Franca FC, Doria MT, Maesaka JY, Ricci MD, Piato JRM, Rocha FBC, Giribela AHG, Gonçalves R, Masili-Oku S, Mano MS, Chala LF, Thompson BM, Baracat EC, Filassi JR. Does conservative surgery treatment for locally advanced breast cancer safe after neoadjuvant treatment? [abstract]. In: Proceedings of the 2017 San Antonio Breast Cancer Symposium; 2017 Dec 5-9; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2018;78(4 Suppl):Abstract nr P2-12-11.</jats:p
De novo phenol bioproduction from glucose using biosensor-assisted microbial co-culture engineering
No full textPeer reviewe
Unlocking the potential of serious games for rehabilitation in low and middle-income countries: addressing potential and current limitations
No full textThe author(s) declare financial support was received for the research, authorship, and/or publication of this article. This research was supported by the NASCERE program (joint research program between Flanders and Jimma University), the VLIR-UOS through their ITP program and the BOF BILA program from UHasselt
Tratamientos farmacológicos y no farmacológicos para la ansiedad al tratamiento estomatológico
No full textIntroduction: dental anxiety significantly affects the individual´s oral health because patients avoid dental treatment and obstruct the dentist in his performance when providing care. Therefore, it is important to manage alternatives to face this phenomenon as a way of controlling or eliminating it. Objective: to determine the pharmacological and non-pharmacological treatments for dental anxiety. Methods: a literature review on the types of maneuvers to face dental anxiety published from 2010 to November 2015 was made. This search was specifically directed to scientific articles. One hundred and thirty five articles that addressed treatment of this disorder were found, excluding those presenting treatments for special patients or with phobias, and the final number was 102 papers. From the latter, 59 were taken to be considered according to the author´s criteria because they thoroughly described the study subject. Data analysis and integration: there are several alternative treatments for anxiety including the non-pharmacological methods such as music therapy, audiovisuals, virtual reality, hypnosis, among others, which are widely used by dental professionals. Moreover, pharmacological treatments mainly use drugs of choice such as benzodiazepines and nitrous oxide mixed with oxygen, being Midazolam the most used due to its good results. The combinations of both types of treatment are also effective. Conclusions: the use of music therapy, virtual reality and audiovisuals are the most used non-pharmacological treatments before this phenomenon. Midazolam and nitrous oxide in combination with oxygen are the most commonly used pharmacological treatments for dental anxiety, mainly in children.Introducción: la ansiedad al tratamiento estomatológico afecta de manera importante la salud bucal del individuo, ya que los pacientes evitan los tratamientos dentales así como interfieren el desempeño del profesional a la hora de brindar la atención. Por lo expuesto se hace importante el manejo de las alternativas para este fenómeno como forma de controlar o eliminar dicha alteración. Objetivo: determinar los tratamientos farmacológicos y no farmacológicos para la ansiedad al tratamiento estomatológico. Métodos : se realizó una revisión bibliográfica sobre los tipos de manejos ante la ansiedad al tratamiento estomatológico publicados en el 2010 hasta noviembre de 2015 en un periodo de 3 meses. Para ello se realizó una búsqueda específicamente de artículos científicos. Se obtuvieron 135 trabajos que abordaban tratamientos de esta alteración, excluyendo aquellos que manejaban tratamientos en pacientes especiales o con fobias, quedando finalmente 102 trabajos. De estos últimos se tomaron 59 por ser considerados a criterio del autor artículos con mayor descripción de la temática a investigar. Análisis e integración de la información: existen diversas alternativas de tratamientos para la ansiedad. Las no farmacológicas abordan técnicas o métodos como musicoterapia, audiovisuales, realidad virtual, hipnosis, entre otras, las cuales son muy usadas por los profesionales. Por otra parte, los tratamientos farmacológicos manejan fundamentalmente como medicamentos de elección las benzodiacepinas y el óxido nitroso mezclado con oxígeno; es el midazolam el que la literatura muestra como más usado por sus buenos resultados. Las combinaciones de los farmacológicos y no farmacológicos son eficaces también. Conclusiones : el uso de medios audiovisuales como la musicoterapia, la realidad virtual así como audiovisuales son los tratamientos no farmacológicos más empleados ante este fenómeno. Por otra parte, el midazolam y el óxido nitroso en combinación con oxígeno constituyen los tratamientos farmacológicos más utilizados para la ansiedad al tratamiento estomatológico, y su aplicación en niños resulta más marcada
Annals of Gadaa System: An Ethnographic PerspectiveEthnography has long been recognized as a scientific description of people and culture in their natural setting. A few studies have examined annals of the Gadaa system. This study attempts to contribute
No full textEthnography has long been recognized as a scientific description of people and culture in their natural setting. A few studies have examined annals of the Gadaa system. This study attempts to contribute to a better understanding of Gadaa system by reviewing related researches at antecedent, present and future levels. The majority of studies were confined to Borana zone but our research work was particularly based on the studies conducted in Guji zone. So it is unique in itself. Drawing on perspectives of records of Gadaa system, the researcher identified the researches year by year and reviewed the items measured, approach used, contribution and research gap. Researchers find that were as “Guji” Gadaa” studies in period between 1977-2007based on structuralism have a constructivist ontology. Furthermore, the results indicate that from 2010-2020, research approach used in Gadaa studies shifted from natural positive realism to over-positive critical realism and after that to critical theory of historical realism. The author also discussed the further challenges and new approach need to be adopted.
 
PREDICTION OF PERFORMANCE AND EMISSION OF COMPRESSED NATURAL GAS (CNG) IN A SUPERCHARGED DIRECT INJECTION SPARK IGNITION ENGINE USING ARTIFICIAL NEURAL NETWORK
No full textEmissions of greenhouse gases such as carbon dioxide, nitrogen oxide and some hydrocarbons have been the main causes of global warming and have posed severe impacts on climate changes. Consequently, the focus on sustainable developments has swiftly grown in recent years. The utilisation of Compressed Natural Gas (CNG) in the spark ignition (SI) engine or using as dual fuel in compression ignition (CI) engine is getting remarkable attention nowadays. In this paper, performance and emission of CNG in supercharged direct injection spark ignition engine were predicted via Artificial Neural Network (ANN). The Levenberg Marquardt training algorithm was used due to its fast response, easy operation and high accuracy. The models’ results are compared with experimental results available from a previous study by the author. It was observed that R2 values for both performance and emission of CNG were higher than 98%, indicating good prediction. Following the training, high accuracy with value higher than 95% was observed for both analyses. Hence, it can be concluded that ANN is a promising technique for the prediction of performance and emission of CNG in direct injection spark ignition engine that consists of numerous inputs and output conditions
