1,721,059 research outputs found
Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassemic children
No full textTreatment of chronic hepatitis D
No full textDespite recent advances in the treatment of chronic viral hepatitis, therapy of chronic hepatitis D is not yet satisfactory. The only option currently available is interferon-alpha (IFN), whose efficacy is related to the dose and duration of treatment. However, the rate of sustained hepatitis D virus (HDV) clearance after a 1-year course with high doses of standard IFN is low. Better results have recently been reported with pegylated IFN both in IFN-naïve and in previous nonresponders to standard IFN, suggesting the use of pegylated IFN as a first-line therapy in chronic hepatitis D. Nucleoside analogues that inhibit hepatitis B virus (HBV) are ineffective against HDV and combination therapy with lamivudine or ribavirin has not shown significant advantages over monotherapy with either standard or pegylated IFN. Because the ultimate goal of treatment is eradication of both HDV and HBV, in responders IFN therapy should be continued as long as possible until the loss of hepatitis B surface antigen, adjusting the dose to patient tolerance. However, because side-effects are common, continuous monitoring is mandatory. Although the first results obtained with pegylated IFN have been encouraging, the rate of sustained virological response is still low and the rate of relapse high, emphasizing the need for developing novel classes of antivirals specifically interfering with the life cycle of this unique viru
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A Study on Socio-Economics Conditions of Pensioners in Myanmar(A Case Study in Hlegu Township) (Shoon Lai Me Me, 2023)
Full text linkThis study highlights the socio-economic condition of pensioners in Hlegu
Township. The purpose of this study is to analyze the socio-economic conditions of
the pensioners and discuss their experiences and difficulties in withdrawling pension.
This study uses descriptive method based on both primary and secondary data and it
conducts with the 150 pensioners in Hlegu Township. Among 150 respondents, retired
civil servants are more than military servants. Male pensioners are older than the
female pensioners. Regarding the educational status, retired civil servants are more
educated than the retired military servants. The majority of pensioners are retirees
who are not working anymore. It is not easy to survive with only pension income for
the old age pensioners. The majority of the pensioners who have the financial support
from their family members survive without loan. The most suffered disease of the
pensioners is hypertension and diabete. For the pensioners, the main difficulties in
withdrawing pension are the long duration and pension payment method. Generally,
the socio-economic conditions of the pensioners who have own business and receive
being look after by their descendants are more blissful than others
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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