460 research outputs found
Studying the History of the Slavic Stishnoy Prologue: New Opportunities and Prospects
No full textThe article was submitted on 31.10.2018.Review of: Petkov, G., Spasova, M. (2008–2014). T"rnovskata redaktsiya na Stishniya Prolog. Tekstove. Leksikalen indeks v 12 t. [The Turnovo Stishnoy Prologue Edition. Texts. Lexical Index. 12 Vols.]. Plovdiv, Paisii Khilendarski. In this review, the author analyses the Tarnovo Edition of the Stishnoy Prologue. Texts: Lexical Index (published by Bulgarian researchers Georgi Petkov and Maria Spasova) and focuses on the structure of the publication, providing a detailed description of the parts of each volume: prologue texts, prologue poems, the lexical index, and the index of saints’ names. The review evaluates the work from the point of view of its academic contribution. The reviewer largely agrees with the authors’ point of view on the history and the study of the Stishnoy Prologue set forth in the preface to the publication. While objecting to some points, the reviewer evaluates the work highly, considering it an important stage in the process of studying the history of the Stishnoy Prologue, one of the most widespread hagiographic calendar collections of the Middle Ages. The publication of the texts of the Stishnoy Prologue, even those in just the Tarnovo edition, can be a powerful catalyst for further textual criticism and linguistic studies of the numerous Russian, Serbian, and Bulgarian copies that have survived to the present day. Ultimately, the reviewed publication can become the basis for a full-scale critical edition of the Stishnoy Prologue. The review emphasises the timeless significance of this publication for Slavic studies, its innovative character, its structural integrity, its theoretical sophistication, and the enormous practical importance of the work for Bulgarian philologists.Рецензия на: Петков Г., Спасова М. Търновската редакция на Стишния Пролог. Текстове. Лексикален индекс : в 12 т. ‒ Пловдив : Паисий Хилендарски, 2008–2014. В рецензии на издание болгарских исследователей Георгия Петкова и Марии Спасовой «Тырновская редакция Стишного пролога. Тексты. Лексический индекс» основное внимание концентрируется на структуре книги. Подробно описываются составные части каждого тома (собственно проложные тексты, проложные стихи, лексический индекс и индекс имен святых), оценивается их научная значимость. Рецензент во многом согласен с точкой зрения авторов на историю изучения и саму историю Стишного Пролога, изложенную в предисловии к книге. Высказывая отдельные несущественные замечания, автор дает высокую оценку данному изданию, определяя его как событие и определенный важный этап в процессе изучения истории текста Стишного Пролога – одного из распространенных агиографических календарных сборников Средневековья. Выход в свет текстов Стишного Пролога даже в одной Тырновской редакции способен стать мощным катализатором дальнейших текстологических и лингвистических исследований многочисленных русских, сербских и болгарских списков, сохранившихся до настоящего времени. В конечном итоге рецензируемое издание может стать основой полномасштабного критического издания Стишного Пролога. В статье подчеркиваются непреходящее значение этого издания для славистической науки, новаторский характер, структурная целостность, высокий теоретический уровень и огромная практическая значимость труда болгарских филологов
Comparative assessment of the indices of the left ventricle post-infarction remodelling of the left ventricle and its dependence on the strategy of acute myocardial infarction management
No full textComparative assessment of the indices of post-infarction remodelling of the left ventricle was carried out in the patients with myocardium reperfusion (thrombolytic therapy) and without reperfusion. ECG was performed for all patients on admission to the hospital and then 3 and 6 months later. The results obtained demonstrated that after the acute period of myocardial infarction there was no difference between the parameters under control. At the same time the results of dynamic monitoring confirmed that later on the patients felt some peculiarities during the left ventricle remodelling process. Three months later there was an increase of the left ventricle sphericity index during the systoly in the patients of group II. Six months later the patients of group II showed significant difference in five indices of remodelling versus the patients on thrombolitic therapy
Search for lepton flavor violation in e+ p collisions at HERA
No full textA search has been made for lepton-flavor-violating interactions of the type e(+)p→lX, where l denotes a mu or tau with high transverse momentum, at a center-of-mass energy roots of 300 GeV with an integrated luminosity of 47.7 pb(-1) using the ZEUS detector at HERA. No evidence was found for lepton-flavor violation and constraints were derived on leptoquarks (LQs) that could mediate such interactions. For LQ masses below roots, limits are set on lambda(eq1) rootbeta(lq), where lambda(eq1) is the coupling of the LQ to an electron and a first-generation quark q(1) and beta(lq) is the branching ratio of the LQ to l and a quark. For LQ masses exceeding roots, limits are set on the four-fermion contact-interaction term lambda(eqalpha) lambda(lqbeta)/M-LQ(2) for leptoquarks that couple to an electron and a quark q(alpha) and also to l and a quark q(beta). Some of the limits are also applicable to lepton-flavor-violating processes mediated by squarks in R- parity-violating supersymmetric models. In some cases involving heavy quarks and especially for l = tau, the ZEUS limits are the most stringent published to date
Leading proton production in e+ p collisions at HERA
No full textEvents with a final-state proton carrying a large fraction of the proton beam momentum, x(L) gt 0.6, and the square of the transverse momentum p(T)(2) lt 0.5 GeV2 T, have been studied in e(+)p collisions with the ZEUS detector at HERA. Data with different photon virtualities were used: Q(2) lt 0.02 GeV2, 0.1 lt Q(2) lt 0.74 GeV2 and 3 lt Q(2) lt 254 GeV2, corresponding to integrated luminosities of 0.9, 1.85 and 3.38 pb(-1). The cross sections are given as a function of x(L), p(T)(2), Q(2) and the Bjorken scaling variable, x. The ratio of the cross section for leading proton production to the inclusive e(+)p cross section shows only a mild dependence on Q(2) and on x. In the region 0.6 lt x(L) lt 0.97, the relative yield of protons is only a weak function of x(L)
Outpatient management of patients with peripheral artery disease by cardiologists or surgeons: influence on the prognosis and prevalence of surgical interventions
No full textHighlights. The study shows for the first time that during the three-year follow-up of patients with diseases of the arteries of the lower extremities in the observation groups of a general surgeon and a cardiologist, adverse events (myocardial infarction, stroke, amputation, disability) and deaths occurred more often in a surgeon than a cardiologist. The study proves the correctness and real benefit of such an approach with the involvement of a cardiologist to the outpatient stage of management of a complex cohort of patients with atherosclerosis of the vessels of the lower extremities.Aim. To study the effect the outpatient observation of patients with peripheral arteries disease (PAD) by cardiologists and surgeons has on timing and prevalence of reconstructive surgery and the prognosis of patients. Methods We analyzed the data on 585 PAD patients who underwent outpatient observation from 2010 to 2017, dividing them into 2 groups. The first group (131 patients) managed by an surgeon; the second (454 patients) managed by a cardiologist. Since the groups were not comparable in terms of the initial parameters, the comparability of patients in the groups (observation by a surgeon or by a cardiologist) was achieved using pseudorandomization. The follow-up period was three years; we assessed the incidence of deaths, adverse events, and the prevalence of reconstructive operations.Results. During a three-year follow-up the 1st group, compared with the 2nd, had more deaths in general (p<0.001), death from cardiac causes (p = 0.045), from stroke (p><0.001), as well as the total number of adverse events (p><0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients. Conclusion Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries. Keywords Peripheral atherosclerosis • Outpatient follow-up • Optimal drug therapy • Reconstructive surgery>˂ 0.001), death from cardiac causes (p = 0.045), from stroke (p˂ 0.001), as well as the total number of adverse events (p˂ 0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients.Conclusion. Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries.Highlights. The study shows for the first time that during the three-year follow-up of patients with diseases of the arteries of the lower extremities in the observation groups of a general surgeon and a cardiologist, adverse events (myocardial infarction, stroke, amputation, disability) and deaths occurred more often in a surgeon than a cardiologist. The study proves the correctness and real benefit of such an approach with the involvement of a cardiologist to the outpatient stage of management of a complex cohort of patients with atherosclerosis of the vessels of the lower extremities.Aim. To study the effect the outpatient observation of patients with peripheral arteries disease (PAD) by cardiologists and surgeons has on timing and prevalence of reconstructive surgery and the prognosis of patients. Methods We analyzed the data on 585 PAD patients who underwent outpatient observation from 2010 to 2017, dividing them into 2 groups. The first group (131 patients) managed by an surgeon; the second (454 patients) managed by a cardiologist. Since the groups were not comparable in terms of the initial parameters, the comparability of patients in the groups (observation by a surgeon or by a cardiologist) was achieved using pseudorandomization. The follow-up period was three years; we assessed the incidence of deaths, adverse events, and the prevalence of reconstructive operations.Results. During a three-year follow-up the 1st group, compared with the 2nd, had more deaths in general (p<0.001), death from cardiac causes (p = 0.045), from stroke (p><0.001), as well as the total number of adverse events (p><0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients. Conclusion Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries. Keywords Peripheral atherosclerosis • Outpatient follow-up • Optimal drug therapy • Reconstructive surgery>˂ 0.001), death from cardiac causes (p = 0.045), from stroke (p˂ 0.001), as well as the total number of adverse events (p˂ 0.001) and disability (p = 0.065). Indications for reconstructive surgery on the lower extremities arteries (LEA), and operations frequency were comparatible in groups. Amputation history, taking diuretics, presence of rhythm disturbances, and management by a surgeon increased the risk of adverse outcomes. Management by a cardiologist, reconstructive LEA surgeries, female sex improved the prognosis of patients.Conclusion. Observation of PAD patients by a cardiologist contributes to a higher frequency of optimal drug therapy by patients and can reduce the number of adverse events in patients and improve their survival without affecting the timing and frequency of reconstructive LEA surgeries
Leading neutron production in e+ p collisions at HERA
No full textThe production of neutrons carrying at least 20% of the proton beam energy (x/sub L/ gt 0.2) in e/sup +/ p collisions has been studied with the ZEUS detector at HERA for a wide range of Q/sup 2/, the photon virtuality, from photoproduction to deep inelastic scattering. The neutron-tagged cross section, ep to e' Xn, is measured relative to the inclusive cross section, ep to e' X, thereby reducing the systematic uncertainties. For x/sub L/ gt 0.3, the rate of neutrons in photoproduction is about half of that measured in hadroproduction, which constitutes a clear breaking of factorisation. There is about a 20% rise in the neutron rate between photoproduction and deep inelastic scattering, which may be attributed to absorptive rescattering in the gamma p system. For 0.64 lt x/sub L/ lt 0.82, the rate of neutrons is almost independent of the Bjorken scaling variable x and Q/sup 2/. However, at lower and higher x/sub L/ values, there is a clear but weak dependence on these variables, thus demonstrating the breaking of limiting fragmentation. The neutron-tagged structure function, F/sub 2//sup LN(3)/ (x,Q/sup 2/,x/sub L/), rises at low values of x in a way similar to that of the inclusive F/sub 2/(x, Q/sup 2/) of the proton. The total gamma pi cross section and the structure function of the pion, F/sub 2//sup pi / (x/sub pi /, Q/sup 2/) where x/sub pi / = x/(1 - x/sub L/), have been determined using a one-pion-exchange model, up to uncertainties in the normalisation due to the poorly understood pion flux. At fixed Q/sup 2/, F/sub 2//sup pi / has approximately the same x dependence as F/sub 2/ of the proton
In Vitro Study of Antiviral Properties of Compounds Based on 1,4-Dioxane Derivative of Closo-Decaborate Anion with Amino Acid Ester Residues Against Influenza Virus A/IIV-Orenburg/83/2012(H1N1)pdm09
No full textNew derivatives of the closo-decaborate anion [B10H9–O(CH2)2O(CH2)3C(O)–L–OCH3]2− (An) (1: L = Trp; 2: L = His; 3: L = Met; 4: L = Ala(2-oxopyrrolidin-3-yl) (Pld) were synthesized and isolated as tetraphenylphosphonium salts (Ph4P)2An. Anions 12−; 22−; 32−, and 42− contain a pendant functional group from the L-tryptophan methyl ester, L-histidine methyl ester, L-methionine methyl ester, or methyl 2-amino-3-(2-oxopyrrolidin-3-yl)propanoate (-Trp–OCH3, -His–OCH3, -Met–OCH3, or -Pld–OCH3) residue, respectively, bonded with the boron cluster anion through the oxybis[(ethane-2,1-diyl)oxy] spacer. This pacer is formed as a result of the nucleophilic opening of the attached dioxane molecule in the [B10H9O(CH2)4O]− starting derivative. Sodium salts of the target compounds were isolated and used in biological experiments. It was established that among compounds Na2An (An = 1–4), not all are capable of inhibiting the cytopathic effect of the virus in vitro. Sodium salts Na2An have a low toxic effect on a monolayer of continuous canine embryonic kidney (MDCK) cell line. Compounds Na21 and Na22 had IC50 of 5.0 and 20.0 μg/mL, respectively, while for compounds Na23 and Na24, IC50 values could not be achieved at the concentrations studied. The studies performed for molecular docking of the anionic part of 12− and 22− with the transmembrane domain of viroporin M2 show some differences in the location of these two ligands inside the M2 canal pore
Study of D*(2010)+- Production in ep Collisions at HERA
No full textWe report the first observation of charmed mesons with the ZEUS detector at HERA using the decay channel D*+ → (D0 → K-π+)π+ (+c.c.). Clear signals in the mass difference ΔM=M(D*)-M(D0) as well as in the M (Kπ) distribution at the D0 mass are found. The ep cross section for inclusive D*± production with Q2 < 4 GeV2 in the γp centre-of-mass energy range 115 < W < 275 GeV has been determined to be (32±7-7+4)nb m the kinematic region {pT(D*) ≥ 1.7 GeV, |η(D*)| < 1-5}. Extrapolating outside this region, assuming a mass of the charm quark of 1.5 GeV, we estimate the ep charm cross section to be σ(ep → cc̄Χ) = (0.45 ± 0.11-0.22+0.37) μb at √s = 296 GeV and 〈W〉 = 198 GeV. The average γp charm cross section σ(γp → cc̄Χ) is found to be (6.3 ± 2.2-3.0+6.3) μb at 〈W〉 = 163 GeV and (16.9 ± 5.2-8.5+13.9) μb at 〈W〉 = 243 GeV. The increase of the total charm photoproduction cross section by one order of magnitude with respect to low energy data experiments is well described by QCD NLO calculations using singular gluon distributions in the proton
The Resonant Center Problem for a 2:-3 Resonant Cubic Lotka–Volterra System
No full textUsing tools of computer algebra we derive the conditions for the cubic Lotka–Volterra system ẋ = x(2 − a20x2 − a11xy − a02y2), ẏ = y(−3+b20x2 + b11xy + b02y2) to be linearizable and to admit a first integral of the form Φ(x, y) =x3y2 + ··· in a neighborhood of the origin, in which case the origin is called a 2: −3 resonant center.</p
- …
