95 research outputs found
The Fracture Properties of Environmental-Friendly Fiber Metal Laminates
No full textThe tensile and impact properties of environmental-friendly composites and FMLs have been investigated. Of the four composites investigated here, a SRPP composite offered superior properties to basalt-, flax-, and hemp fiber-reinforced PP composites. Adding aluminum layers to the outer surfaces of the composites resulted in a significant enhancement in the tensile and impact properties of the laminates. The tensile strength and modulus properties of the FMLs obey a rule of mixtures approach, suggesting that simple procedures can be used to design these hybrid systems. Under low-velocity impact loading, the SRPP, and its associated FML, offered the highest resistance to perforation, as a result of gross plastic deformation in the composite and metal plies. A semi-empirical model, previously employed to characterize metal plates, was used to characterize the low-velocity impact response of the laminates investigated here. The model was capable of predicting the trends in the experimental data with reasonable success. This evidence suggests that environmental-friendly fiber-based FMLs offer significant potential for use in engineering applications
Noninvasive Evaluation of Cardiac Function in Non Hypertensive and Asymptomatic Diabetic Patients
No full textBackground & Objectives: Type 2 diabetes is a major cardiovascular risk factor such as HTN, HLP and smoking. A primary diabetic cardiomyopathy represents a high risk factor for heart failure in the absence of ischemic, valvular and hypertensive heart disease in the diabetic population. CAD is more common in diabetic patients and it is almost asymptomatic.
Unquestionably, an early detection of LV damage and CAD is a major goal for the prevention of cardiac disease in the diabetic population.
Methods: This study was done as Cross-Sectional method. The study sample consisted of 40 patients with type 2 diabetes mellitus without hypertension and cardiac symptoms (mean age 47 years) who recourse to diabetes clinic of Ardabil Emam Khomeini Hospital during 2009-2010. Left ventricular (LV) function was studied by echocardiography and exercise test using Bruce protocol. Data from the patients were collected and analyzed using SPSS 17 software.
Results: All studied cases had a normal systolic function. 22 cases (55%) had diastolic dysfunction and 8 people (20%) had a positive stress test, which all had diastolic dysfunction too.
Conclusion: This study showed that an impairment of left ventricular diastolic function occurs early in the natural history of diabetes mellitus and CAD is more common in diabetic patients with diastolic dysfunction
Effects of culturally tailored hypertension education program among Chinese Americans
No full textPurpose of Project: Hypertension (HTN) prevalence in Asians has risen dramatically compared with other ethnic groups in recent years. This quality improvement project used a faith-based setting to provide an HTN education program to improve awareness and management of HTN among Chinese. This project aimed to assess the effectiveness of the HTN education program on HTN knowledge, self-monitoring blood pressure (SMBP) techniques, lifestyle modification behaviors, and blood pressure (BP) measurement.
Methodology: This project used a pre-and post-test design with interventions using American Heart Association (AHA) guided HTN education. Ten participants were recruited at a local Chinese Church. The participants received 60 minutes of in-person educational sessions on weeks one and two while providing baseline HTN knowledge, lifestyle modification behavior, SMBP, and BP measurement. The participants also received weekly text message reminders on weeks three and four regarding lifestyle modification. On Week Five, the participants repeated the HTN knowledge test, survey behavior changes, SMBP, and completed the program evaluation survey. Descriptive statistics, McNemar's test, and the Wilconxon-signed rank test were used to analyze the data.
Results: Although there was no statistical significance of the overall change. When comparing participants' individual results, there were noted differences. There was an improvement in HTN knowledge, SMBP, lifestyle modification and BP measurement.
Implication for Practice: The project results consigned with previous research with the need to focus on HTN education in primary care settings. Integrating HTN knowledge, lifestyle modification, and proper SMBP can help manage HTN. Reinforcement of lifestyle modification can work synergistically along with pharmacological therapy. A simple health program can fill gaps in the primary care setting by improving patient quality and safety. Thus, reducing the morbidity of HTN complications and reducing the economic burden. This project demonstrated a faith-based community as an excellent opportunity for implementing a population culturally tailored health program.D.N.P.Includes bibliographical reference
Prevalence of Hypertension and Prehypertension in Iranian Children
No full textBackground: Hypertension (HTN) is a significant public health problem worldwide. Early diagnosis of HTN and its related risk factors has been considered as one of the main requirements of general healthcare in children. Objectives: This study aimed to examine the nomograms of normal systolic and diastolic blood pressure (BP) and the prevalence of asymptomatic HTN and pre-HTN in a population of school-aged children. Methods: Systolic and diastolic BP, height, and weight were measured in 5811 healthy school-aged children (2904 males and 2907 females) during healthcare visits. HTN was defined as systolic or diastolic BP � 95th percentile for age, gender, and height of the screened population on � 3 occasions. Pre-HTN was considered as systolic or diastolic BP between 90-95 percentile. Results: HTN and pre-HTN were detected in 8.4 and 7.8 of the children, respectively. The prevalence of HTN was 8.6 among the males and 8.2 among the females. Systolic HTN and pre-HTN were detected in 5.8 and 6.4 of the cases compared to diastolic HTN and pre-HTN observed in 5.9 and 6.1 of the participants, respectively. In addition, HTN was detected in 27.9 of children with obesity. Conclusions: According to the high incidence of asymptomatic HTN and pre-HTN in asymptomatic children, it is recommended to perform routine BP measurement during medical care visits of all healthy school children and to prevent and treat obesity in childhood. © 2021, Author(s)
Prevalence and incidence of pre-hypertension and hypertension (awareness/control) in Iran: findings from Kerman coronary artery diseases risk factors study 2 (KERCADRS)
No full textHypertension (HTN) is an important cause of cardiovascular-related morbidity and mortality. The present study was conducted to investigate the prevalence and incidence rate of pre-HTN, diagnosed and undiagnosed HTN, as well as its control and associated factors in adult population in southeast Iran. In a randomized household survey, 9987 participants aged 15�80 years were recruited into the study. HTN was confirmed through examination or using antihypertensive drug(s). Pre-HTN and HTN were defined as 120�139/80�89 and �140/90 mmHg for systolic and diastolic BP, respectively. The prevalence of pre-HTN was 28.5. The prevalence of HTN was 19.2 (13.9 diagnosed and 5.3 undiagnosed). HTN increased with age (from 4 in 15�24 to 67.8 in 75�80 years). Men had higher pre-HTN (35.6 vs. 23.4) and undiagnosed HTN (7.5 vs. 3.8) than women. Of those diagnosed, 46.5 had uncontrolled BP, in which, women had better conditions than men (45.6 vs. 47.4). Obesity, positive family history of HTN, anxiety, and low physical activity were the most significant predictors of HTN. The prevalence of pre-HTN decreased but there was no change in the prevalence of HTN during the last 5 years. The 5-year incidence rate/100 person-years of pre-HTN and HTN was 6.6 and 3.7, respectively. Although there are some promising signs of reducing pre-HTN and slowing HTN rise, currently, almost one-fifth of the adult population suffers from HTN. Given the poor BP control in patients with diagnosed HTN, especially in men, alarms that more effective interventions and strategies are needed to reduce deleterious consequences of HTN. © 2020, The Author(s), under exclusive licence to Springer Nature Limited
Essential Hypertension in Adults
No full textThe author chose to write about hypertension because she takes care of patients and family members with hypertension on a frequent basis, and is likely to face the challenge of managing patients with hypertension (HTN) in her future role as a nurse practitioner due to the high prevalence of HTN among men and women
A pseudotype vesicular stomatitis virus containing Hantaan virus envelope glycoproteins G1 and G2 as an alternative to hantavirus vaccine in mice
No full textWe examined whether a vesicular stomatitis virus (VSV) pseudotype bearing the hantavirus envelope glycoproteins (GPs) G1 and G2 (VSVÎ G*HTN) could be used as a safe and effective alternative to native hantavirus. Mice were immunized with purified particles of VSVÎ G*HTN. After the second immunization, all mice produced anti-GP antibody as detected in ELISA and a neutralization test. After the third immunization, the mice were challenged with Hantaan virus. Neither anti-NP antibody production nor Hantaan virus-specific CD8 T-cell reactions were detected in these mice. The present study demonstrated the potential of using a pseudotype VSV system as a tool for developing a hantavirus vaccine
EPIDERMAL REMNANTS OF PROTEROSUCHUS VANHOEPENI (HTN)
No full textEpidermal remnants from Proterosuchus vanhoepeni are described. The significance of
these findings is briefly discussed.The author was supported by a Senior Bursary from the University of the Witwatersran
A self-measured blood pressure protocol to improve medication adherence and blood pressure control
No full textBackground & Significance: People with hypertension (HTN) living in poverty have a higher risk of developing end-organ damage and dying from complications than those living in wealthier areas.
Purpose of Project: To decrease the risk of HTN-related complications by implementing an evidence-based protocol of self-measured blood pressure (SMBP) monitoring with weekly personal support calls to improve blood pressure (BP) control and medication adherence among low-income minorities.
Methodology: This study used a quasi-experimental design. Patients from a private primary care practice were recruited. All participants received a 45-min in-person educational session on SMBP and a 15-min phone call weekly for four weeks. Participants were to collect and report BP readings weekly. A validated instrument to evaluate a patients’ adherence to HTN therapy: Hill-Bone Compliance to High Blood Pressure Therapy scale (HB-HBP), was used to collect pre and post-intervention scores.
Results: Nine participants completed the project. The majority of the participants' ages ranged from 60-79 yrs, about 55% had HTN for over 10 yrs, and about 32% reported knowing the proper techniques to measure their BP at home. A statistically significant improvement in the mean SBP readings (p= 0.028) and HB-HBP scores (p=0.012) occurred from pre to post-intervention. Medication adherence alone was not statistically significant (p= 0.056).
Implications for Practice: Although there wasn’t a significant improvement in medication adherence, this study indicated a statistically significant improvement in SBP and adherence to HTN therapy. The potential impact is a reduction in the adverse sequala of uncontrolled HTN.D.N.P.Includes bibliographical reference
Serum uric acid and the risk of hypertension in a Middle Eastern cohort: A 10-year prospective study discovering BMI-mediated associations and gender-specific vulnerabilities
No full textHypertension (HTN), a modifiable cardiovascular risk factor, remains a global public health challenge. Serum uric acid (SUA) has been implicated in HTN pathogenesis, but the evidence is conflicting. This study investigated the association between SUA and 10-year HTN incidence, stratified by sex and body mass index (BMI), in a Middle Eastern cohort. A 10-year prospective cohort analysis using data from 828 adults (53.5% male) aged 20 to 74 years in Yazd, Iran, sourced from the Yazd Healthy Heart Project. Participants free of baseline HTN (defined as systolic blood pressure/diastolic blood pressure 5.5 mg/dL [males], >4.6 mg/dL [females]) and normouricemic groups. Incident HTN was defined as systolic/diastolic blood pressure ≥ 130/80 mm Hg, antihypertensive use, or medical diagnosis. Hyperuricemia was associated with a 59% higher HTN risk (odds ratio [OR] = 1.59, 95% confidence interval [CI]: 1.14-2.20), but this attenuated after BMI adjustment (OR = 1.16, 95% CI: 0.73-1.85). Stratified analyses revealed borderline associations in men (adjusted OR = 1.79, 95% CI: 1.01-3.19, P = .05) and normal-weight individuals (BMI < 25 kg/m²: OR = 2.32, 95% CI: 1.04-5.22), persisting across adjustment models. No associations were observed in the women or overweight/obese subgroups. Hyperuricemic individuals exhibited higher baseline BMI and dyslipidemia (P < .01). Elevated SUA independently predicts HTN risk in men and normal-weight individuals, suggesting context-dependent mechanisms. Adiposity mediates the population-level association, while SUA's direct vascular effects may dominate in leaner subgroups.
Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc
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