117,891 research outputs found
Finding New Ways to Treat Kidney Disease
No full textChronic kidney disease affects millions of people in the U.S. and worldwide; however, current treatments are not highly effective. Many factors contribute to chronic kidney disease, including diabetes, hypertension, autoimmune disorders, and others. Research in the lab of University of Utah Health investigator Donald Kohan, MD, PhD, used genetically engineered mice to help identify a peptide, endothelin-1, and its receptor, ETA, as key regulators of blood pressure and kidney function in health. Kohan and colleagues also helped determine that kidney ET-1 production is increased in many kidney diseases and, through activation of ETA receptors on most kidney cell types, leads to inflammation, scarring, and decreased kidney function. Together with national and international collaborators, they have translated these studies into clinical trials demonstrating that blocking the ETA receptor protects kidney function in individuals with type 2 diabetes mellitus. These trials with ETA receptor antagonists are now being extended into other forms of chronic kidney disease. Targeting the endothelin-1/ETA receptor system represents a promising approach to the treatment of chronic kidney disease
Effects of hydrolysis ageing on the performance and dimensional stability of glass-fiber reinforced polyamide 66
No full textResults of an in-depth study of hydrolysis testing on the mechanical performance, weight change, and dimensional stability of injection moulded glass-fiber reinforced polyamide 66 automotive composites are presented. Composite and resin samples have been characterised after conditioning in water-glycol mixtures at 70°C, 120°C and 150°C for a range of times up to 1000 hours. The results reveal that hydrothermal ageing results in significant changes in the mechanical performance, weight, and dimensions of these materials. Mechanical performance after conditioning at different temperatures could be superimposed when considered as a function of the level of fluid absorbed by the composite matrix
Tradición y cultura crítica en el marxismo argentino
No full textSegún Gramsci las tradiciones político-culturales viven en la continuidad de los grupos intelectuales. ¿Qué sucede cuando determinados colectivos han sido disgregados sufriendo la tortura, la cárcel, el exilio, el secuestro, el asesinato o la desaparición? ¿Se anula y desaparece la tradición? ¿Es posible repensarla y revisitarla -haciendo un balance de inventario- en una nueva fase histórica? En Argentina, después del genocidio militar de 1976 debemos repensar estas preguntas. Este libro intenta indagar en materiales de archivo, en entrevistas en profundidad, en reconstrucciones y comparaciones bibliográficas para poder bordar semejantes interrogaciones.Fil: Kohan, Néstor Boris. Universidad de Buenos Aires. Facultad de Ciencias Sociales. Instituto de Estudios de América Latina y el Caribe; Argentin
Культуротворческий потенциал украинского киноведения: опыт 2000 – 2010 годов
No full textCultural and creative potential of Ukrainian cinema science: experience 2000 - 2010 years The article gives an analysis the concepts of the Ukrainian film experts of the first decade of XXI century, reflecting the new aspects of the theoretical approaches in both history of the Ukrainian cinema and the contemporary cinematic trends. Analyzed the works of famous Ukrainian film critics of the older generation - M. Braterskaya-Dron, L. Bryukhovetskaya, I. Zubavina, O. Musienko, A. Rutkovsky, V. Skuratovsky, S. Trymbach, A. Chmil, as well as the work of young researchers
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Letter from unknown writer to Jesse L. Boyce
No full textLetter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Sarah L. Blum Author Visit - Warrior Nurse: PTSD and Healing
No full textHear Sarah L. Blum, author of Women Under Fire: Abuse in the Military, discuss her newest book, Warrior Nurse: PTSD and Healing followed by a Q&A and book signing.
Sarah L. Blum is a decorated Vietnam veteran who served as an operating room nurse during the intense fighting of 1967. In recognition of her service, she was awarded the Army Commendation Medal.
Sponsored by CWU Veterans Center and CWU Libraries.https://digitalcommons.cwu.edu/libraryevents/1252/thumbnail.jp
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