24 research outputs found
Image Restoration using a Wiener Filter
No full textIn this paper, we will study image processing in the frequency domain and its related Fourier transforms. Filtering in the frequency domain is essentially the same with filtering in the spatial domain, so we have a choice of using the domain that will be easier and faster in calculating or making filtering algorithms. Furthermore, we will see the properties of energy distribution of an image.
Synthetically, a nice filter, known as the Wiener filter, is shown and will be implemented for analysis.목차
1 Introduction = 1
1.1 Image Processing in the Frequency Domain = 1
1.2 Discrete Fourier Transform = 2
1.3 Fast Fourier Transform = 4
2 Filtering in the Frequency Domain = 7
3 Energy Distribution of Image = 13
4 Image Restoration in the Frequency Domain = 17
4.1 Image Restoration = 17
4.2 Wiener Filter = 18
4.3 Numerical examples using a Wiener filter = 21
5 Conclusions = 2
Gabor frames with trigonometric spline dual windows
No full textA Gabor system is a collection of modulated and translated copies of a window function. If we have a signal in , it can be analyzed with a Gabor system generated by a certain window and then synthesized with a Gabor system generated by another window . If this leads us to a perfect reconstruction, we say that and are dual Gabor windows.
Few explicit examples of dual window pairs are known. This thesis constructs explicit examples of Gabor dual windows with trigonometric form. The windows have fixed support and have an arbitrary smoothness.
Also, in the discrete time domain, the trigonometric form allows us to evaluate the Gabor coefficients efficiently using the Discrete Fourier Transform.
For the higher dimensional cases, we find window examples for a large class of modulation parameter lattices, including shear lattices. Also, a sufficient condition on the norm of the modulation lattice to have explicit dual Gabor windows is presented, for every dimension.Item withdrawn by Mark Zulauf ([email protected]) on 2011-07-01T20:21:55Z
Item was in collections:
University of Illinois Theses & Dissertations (ID: 1)
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Kim_Inmi.pdf: 12453581 bytes, checksum: cd677405c5e50579f2fcc6966676cabd (MD5)Made available in DSpace on 2011-08-25T22:10:11Z (GMT). No. of bitstreams: 3
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Kim_Inmi.tex: 149708 bytes, checksum: 09bb9931d8d15b5c870ef127349d9cec (MD5
An Enhanced Algorithm of RNN Using Trend in Time-Series
No full textThe concept of trend in data and a novel neural network method for the forecasting of upcoming time-series data are proposed in this paper. The proposed method extracts two data sets—the trend and the remainder—resulting in two separate learning sets for training. This method works sufficiently, even when only using a simple recurrent neural network (RNN). The proposed scheme is demonstrated to achieve better performance in selected real-life examples, compared to other averaging-based statistical forecast methods and other recurrent methods, such as long short-term memory (LSTM)
Genome-based exome sequencing analysis identifies GYG1, DIS3L and DDRGK1 are associated with myocardial infarction in Koreans
No full textMyocardial infarction (MI) is a complex disease caused by combination of genetic and environmental factors. Although genome-wide association studies (GWAS) identified more than 46 risk loci which are associated with coronary artery disease and MI, most of the genetic variability inMI still remains undefined. Here, we screened the susceptibility loci for MI using exome sequencing and validated candidate variants in replication sets. We identified that three genes (GYG1, DIS3L and DDRGK1) were associated with MI at the discovery and replication stages. Further research will be required to determine the functional association of these genes with MI risk, and these associations have to be confirmed in other ethnic populations.restrictio
복강경 수술 로봇 시스템의 활용도 향상을 위한 추가적인 마스터 인터페이스 개발과 이를 이용한 응용 시스템 개발 연구
No full text학위논문 (박사)-- 서울대학교 대학원 공과대학 협동과정 바이오엔지니어링전공, 2017. 8. Sungwan Kim.Robot-assisted laparoscopic surgery offers several advantages compared to open surgery and conventional minimally invasive surgery. However, important issues which need to be resolved are the complexity of current operation room environment for laparoscopic robotic surgery and demand for a larger operation room. To overcome these issues, additional interfaces based on Hands-On-Throttle-And-Stick (HOTAS) concept which can be simply attached and integrated with master interface of da Vinci surgical robot system were proposed. HOTAS controller is widely used for flight control in the aerospace field which can manipulate hundreds of functions and provide feedback to the pilot on flight conditions. The implementation of HOTAS controller significantly reduced the complexity of flights and reduced the number of pilots required in a cockpit from two to one.
In this study, to provide above benefits to the operation room for robotic laparoscopic surgery, two types of additional interfaces are proposed. Proposed additional interfaces can be easily manipulated by the surgeons index finger, which is currently operated only by finger clutch buttons, and therefore enable the surgeon to use multiple functions. Initially, a novel master interface (NMI) was developed. The NMI mainly consists of a 9-way switch and a microprocessor with a wireless communication module. Thus, the NMI can be also regarded as a 9-way compact HOTAS. The performance test, latency, and power consumption of the developed NMI were verified by repeated experiments. Then, an improved novel master interface (iNMI) was developed to provide more intuitive and convenient manipulation. The iNMI was developed based on a capacitive touch sensor array and a wireless microprocessor to intuitively reflect the surgeons decision. Multiple experiments were performed to evaluate the iNMI performance in terms of performance test, latency, and power consumption.
In addition, two application systems based on Surgical-Operation-By-Wire (SOBW) concept are proposed in this research to enhance the function of laparoscopic surgical robot system based on clinical needs that are stated below. The size of the additional interface is small enough to be easily installed to the master tool manipulators (MTMs) of da Vinci research kit (dVRK), which was used as an operation robot arm system, to maximize convenience to the surgeon when using the additional interfaces to simultaneously manipulate the application systems with the MTMs.
Firstly, a robotic assistant that can be simultaneously manipulated via a wireless controller is proposed to allow the surgeon to control the assistant instrument. This approach not only decreases surgeon fatigue by eliminating communication process with assistants, but also resolves collision between the operation robot arms and the assistant instruments that can be caused by an inexperienced assistant or miscommunication and misaligned intent between the surgeon and the assistant. The system comprises two additional interfaces, a surgical instrument with a gripper actuated by a micromotor and a 6-axis robot arm. The gripping force of the surgical instrument was comparable to that of conventional systems and was consistent even after 1,000 times of gripping motion. The workspace was calculated to be 8,397.4 cm3. Recruited volunteers were able to execute the simple peg task within the cut-off time and successfully performed the in vitro test.
Secondly, a wirelessly controllable stereo endoscope system which enables simultaneous control with the operating robot arm system is proposed. This is able to remove any discontinuous surgical flow that occurs when the control is swapped between the endoscope system and the operating robot arm system, and therefore prevent problems such as increased operation time, collision among surgical instruments, and injury to patients. The proposed system consists of two additional interfaces, a four-degrees of freedom (4-DOFs) endoscope control system (ECS) and a simple three-dimensional (3D) endoscope. The 4-DOFs ECS consists of four servo motors and employs a two-parallel link structure to provide translational and fulcrum point motions to the simple 3D endoscope. The workspace was calculated to be 20,378.3 cm3, which exceeds the reference workspace. The novice volunteers were able to successfully execute the modified peg transfer task.
Throughout the various verifications, it has been confirmed that the proposed interfaces could make the surgical robot system more efficiently by overcoming its several limitations.1. Introduction 1
1.1. Robotic Laparoscopic Surgery 1
1.2. Objectives and Scope 8
1.2.1. Additional Master Interfaces 14
1.2.2. Application Systems 15
2. Materials and Methods 20
2.1. Additional Master Interfaces 20
2.1.1. Novel Master Interface: 9-way Compact Hands-On-Throttle-And-Stick 20
2.1.2. improved Novel Master Interface: Capacitive Touch Type Compact Hands-On-Throttle-And-Stick 26
2.2. Application Systems 34
2.2.1. Robotic Assistant 34
2.2.2. Stereo Endoscope System 49
3. Results 57
3.1. Novel Master Interface with Application Systems 57
3.1.1. Novel Master Interface 57
3.1.2. Robotic Assistant 59
3.1.3. Novel Master Interface with Robotic Assistant 67
3.1.4. Stereo Endoscope System 76
3.1.5. Novel Master Interface with Stereo Endoscope System 82
3.2. improved Novel Master Interface with Application Systems 87
3.2.1. improved Novel Master Interface 87
3.2.2. improved Novel Master Interface with Stereo Endoscope System 90
4. Discussion 91
5. Conclusion 102
References 105
Abstract in Korean 117Docto
Sperimentazione di un modello interdisciplinare per sviluppare istituzioni e policy basate sul valore delle competenze
No full textIntroduction Coaching is a personal development method that provides specific support towards acquiring a higher degree of awareness, responsibility, choice, trust and autonomy. This application in Health Care is developed in Italy by IPACS (Institutional & Public Coaching Services) within a methodology that integrates Mentoring - Individual Coaching - Team Coaching - Classroom Training, and lasts about 6 months. The aim of the study was to demonstrate how an integrated Coaching program could have an impact on the development of soft and hard skills mainly related to inter-disciplinary roles, and positively influence the achievement of System objectives set in the National Chronicity Plan by the Ministry of Health.
Materials and Methods An integrated program of Coaching was applied to 2 Teams of Institutional professionals (18 of ASL Roma 4 and 23 of the National Institute for Infectious Diseases L. Spallanzani in Rome).
Corresponding author:
Francesca Cioffi
[email protected]
Open access
In particular, the objectives shared in the action plan for ASL Roma 4 were the Reorganization of the First Intervention Point on the Territory, and the Inclusion of the Family Nurse in the Community while for the INMI L. Spallanzani were the Improvement of Retention in Care and the Multidisciplinary Management of Fragile Patients with Chronic Infectious Diseases. The improvement in the core skills (Communication, Result Orientation, Teamworking, Negotiation) was measured with an Assessment pre and post Coaching program. Capacity development was defined as effective for an increase score of at least 0.5 and excellent for at least 1.5 points. Intermediate results in skills development were monitored with an observation template. An action plan monitoring was carried out through the IPACS Empowerment platform®.
Results During the study period, from February to September 2019, the 41 professionals involved reported the most important improvements in the ability t
Real-world effectiveness of sofosbuvir/velpatasvir for the treatment of hepatitis C virus in prison settings
No full text20.500.12530/87870Plain language summary Achievement of elimination of HCV as a major public health threat requires focus on vulnerable populations such as people in prison. The prison population is at high risk of HCV infection but their treatment is complicated by social issues such as mental health disorders and drug use. Simple and effective treatment regimens are required to increase access to treatment and improve cure rates. This real-world analysis across Europe and Canada analyzed data from 20 prison populations. HCV-infected individuals were treated with sofosbuvir/velpatasvir, a once daily treatment which requires minimal monitoring. This regimen achieved high cure rates in the prison population despite the existence of complicating social issues.Background: People in prison are at high risk of hepatitis C virus (HCV) infection and often have a history of injection drug use and mental health disorders. Simple test-and-treat regimens which require minimal monitoring are critical. Methods: This integrated real-world analysis evaluated the effectiveness of once daily sofosbuvir/velpatasvir (SOF/VEL) in 20 prison cohorts across Europe and Canada. The primary outcome was sustained virological response (SVR) in the effectiveness population (EP), defined as patients with a valid SVR status. Secondary outcomes were reasons for not achieving SVR, adherence and time between HCV RNA diagnosis and SOF/VEL treatment. Results: Overall, 526 people in prison were included with 98.9% SVR achieved in the EP (n = 442). Cure rates were not compromised by drug use or existence of mental health disorders. Conclusion: SOF/VEL for 12 weeks is highly successful in prison settings and enables the implementation of a simple treatment algorithm in line with guideline recommendations and test-and-treat strategies
SUGT1 controls susceptibility to HIV-1 infection by stabilizing microtubule plus-ends
No full text© 2020, The Author(s), under exclusive licence to ADMC Associazione Differenziamento e Morte Cellulare. Understanding the viral–host cell interface during HIV-1 infection is a prerequisite for the development of innovative antiviral therapies. Here we show that the suppressor of G2 allele of skp1 (SUGT1) is a permissive factor for human immunodeficiency virus (HIV)-1 infection. Expression of SUGT1 increases in infected cells on human brain sections and in permissive host cells. We found that SUGT1 determines the permissiveness to infection of lymphocytes and macrophages by modulating the nuclear import of the viral genome. More importantly, SUGT1 stabilizes the microtubule plus-ends (+MTs) of host cells (through the modulation of microtubule acetylation and the formation of end-binding protein 1 (EB1) comets). This effect on microtubules favors HIV-1 retrograde trafficking and replication. SUGT1 depletion impairs the replication of HIV-1 patient primary isolates and mutant virus that is resistant to raltegravir antiretroviral agent. Altogether our results identify SUGT1 as a cellular factor involved in the post-entry steps of HIV-1 infection that may be targeted for new therapeutic approaches
Long-term virological suppression on first-line efavirenz plus tenofovir=emtricitabine/lamivudine for HIV-1
No full textObjectives: Evaluate long-term rates of virological failure and treatment interruption for people living with HIV (PLWHIV) with viral suppression on first-line efavirenz+tenofovir disoproxil fumarate+emtricitabine/lamivudine (EFV+TDF+FTC/3TC), and compare these according to patient characteristics.Methods: PLWHIV enrolled in the Collaboration of Observational HIV Epidemiological Research Europe cohort collaboration, who started first-line EFV+TDF+FTC/3TC at age at least 16 years and had viral suppression (= 200 copies/ml) and (complete) treatment interruption were estimated according to years since initial suppression. We used Poisson regression to examine associations of baseline characteristics with rates of virological failure or treatment interruption.Results: Among 19 527 eligible PLWHIV with median (interquartile range) follow-up 3.7 (2.0-5.6) years after initial viral suppression, the estimated rate of the combined incidence of virological failure or treatment interruption fell from 9.0/100 person-years in the first year to less than 4/100 person-years beyond 3 years from suppression; considering only those remaining on EFV+TDF+FTC/3TC, the combined rate dropped from 8.2/100 person-years in the first year to less than 3.5/100 person-years beyond 3 years. PLWHIV with injecting drug-related or heterosexual transmission were at higher risk of virological failure or treatment interruption, as were those of Black ethnicity. PLWHIV aged less than 35 years were at higher risk of virological failure and treatment interruption.Conclusion: PLWHIV starting first-line EFV+TDF+FTC/3TC had low rates of virological failure and treatment interruption up to 10 years from initial suppression. Demographic characteristics can be used to identify subpopulations with higher risks of these outcomes. Copyright (C) 2019 The Author(s). Published by Wolters Kluwer Health, Inc
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TWENTY-FIFTH YEAR.
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Phone P. A. 78 511 Alma Street
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HIGH SCHOOL PLAY JUDGE CHARLES STAHFORD FACULTY
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UNIVERSITY GARAGE
H.'F. Wm. Btockmann. Prop.
328 University Avenue Phone P. A. 24
