581 research outputs found
Functioning of the Customs Administration of the Kingdom of Poland in Russia in 1914–1917 (until the Fall of the Romanov Monarchy)
No full textIn late July and early August 1914, with the rising threat of war, customs administration structures of the Kingdom of Poland were evacuated to Russia. The administrative personnel and their families, as well as the assets of the customs offices were removed to the interior governorates of the Russian Empire. Russian authorities assumed that the forced stay outside the Kingdom of Poland would be short-lived, counting on the military successes of the tsarist army. However, due to the Russian army’s loss of strategic initiative, these offices never returned to the Kingdom of Poland. Based on surviving source materials, the article presents the process of the evacuation in 1914, and the operation of the evacuated Russian customs administration structures until the fall of the Romanov monarchy in March 1917.Na przełomie lipca i sierpnia 1914 r. w głąb Rosji ewakuowano struktury administracji celnej z terenu Królestwa Polskiego z powodu groźby wybuchu wojny. Do wewnętrznych guberni Imperium Rosyjskiego wywieziono personel administracyjny wraz z rodzinami oraz majątek urzędów celnych. Władze rosyjskie zakładały, że przymusowy pobyt poza Królestwem Polskim będzie krótkotrwały licząc na sukcesy militarne armii carskiej. Jednak z powodu utracenia inicjatywy strategicznej przez armię rosyjską urzędy te nigdy nie powróciły do Królestwa Polskiego. Na podstawie zachowanych materiałów źródłowych przedstawiono proces ewakuacji w 1914 r. i zjawisko funkcjonowania rosyjskich struktur administracji celnej przebywającej na ewakuacji do chwili upadku monarchii Romanowów w marcu 1917 r
„Biohistoriograficzne” prace naukowe na Ukrainie od czasów odzyskania niepodległości. Ujęcie ilościowe
No full textThe aim of the paper is discovering how the new demands for modernization of the biographical discourse after biographical turn are met and realized in the current Ukrainian biographical research. The author will approach this through looking at avtoreferats (abstracts) of dissertations on biographical topics that have been defended in Ukraine in the past thirty years. The present work is based on quantitative methods. It draws on the analysis of a relational database of historiographical dissertations defended over the period from 1991 to 2020, built in Microsoft Access. Analysis of the database provides an opportunity to answer a number of new research questions: about the dynamics of biographical dissertation writing and defense over time, circle of humanities scholars whose life and activities have been the subject of dissertation-level historiographical studies in recent decades, methodological foundations of biographical studies (special methodological concepts and tools) on the basis of classification of dissertations in biographical studies, finally, the database also allows us to analyze the authors of biographical dissertations as a group and detect the existence of research communities (academic schools) in the field of biographical studies.Celem poniższego artykułu jest przedstawienie w jaki sposób potrzeba aktualizacji dyskursu biografistycznego jest realizowana w obecnym ukraińskim nurcie badawczym. Autorka podejmuje się analizy abstraktów naukowych rozpraw poruszających tematy biografii, które obroniono na przestrzeni ostatnich trzydziestu lat. Artykuł wykorzystuje metody ilościowe, czerpiąc z analizy relacyjnej bazy danych prac historiograficznych bronionych w latach 1991–2020, która stworzona została w programie Microsoft Access. Umożliwia to zrozumienie wielu problemów badawczych m.in. dynamiki pisania oraz publikowania rozpraw w ostatnim trzydziestoleciu. Nakreśla ona także krąg badawczy, którego aktywność była przedmiotem badań na poziomie rozpraw z dziedziny biografistyki, ale i definiuje podstawy metodologiczne studiów biografistycznych (pojęcia i narzędzia z zakresu metodologii) w oparciu o klasyfikację prac badawczych w studiach biografistycznych. W swoim artykule autorka kreśli także grupowy portret autorów tych prac, poświadczając egzystencji środowisk naukowych (szkół badawczych) w dziedzinie nauk biografistycznych
The phenomenon of Yulia Tymoshenko in politics of Ukraine
No full textYulia Tymoshenko's leadership style and leadership are analy¬zed and described in this article. The author stated that political opposition was a natural element for Tymoshenko. Her time as Prime Minister was rather controversial, hence the assessements of her successes and failures propensities to vary. A description of Tymoshenko as a political party leader that included the way she chose people to work with was also given
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
"Yulia" by N. M. Karamzin: the first experience of creating a high society story in Russian literature
No full textВ статье рассматривается повесть Н. М. Карамзина "Юлия" в аспекте жанра. В ходе анализа приводятся дополнительные аргументы в пользу того, что "Юлия" является первой в отечественной литературе светской повестью, давшей начало перспективной жанровой традиции.In the article N. M. Karamzin's story "Yulia" is considered in aspect of a genre. During the analysis the author of the article brings the additional arguments in favor of the fact that "Yulia" is the first "high society story" in the domestic literature. Such a story opened a perspective genre tendency for further literature
UPAYA-UPAYA ROOM ATTENDANT DALAM MEMELIHARA KENYAMANAN TAMU DI VASA HOTEL SURABAYA
No full textThe goal to be achieved in this research is to find out the efforts made by the room
attendant in maintaining guest comfort at Vasa hotel Surabaya so that guests feel
happy, satisfied and want to visit again at Vasa Hotel Surabaya. The author makes
observations of the room attendant's efforts in maintaining guest comfort. The
author concludes that the efforts made by the room attendant in maintaining guest
comfort at Vasa hotel Surabaya are as follows: Maintain cleanliness, greet guests
and offer assistance, pause and say hello when meeting guests in the corridor area
or other places other than the room. , and provides towel folding services (towel
art) and has also carried out standard operating room attendant procedures
“To live your life not in vain”. Ukrainian academics’ experience of forced migration in Poland
No full textThe authors consider the forced migration of Ukrainian academics to Poland caused by the Russian-Ukrainian War, particularly the expansion of communication between the Ukrainian and Polish academic communities and the experience gained in this process. The study is based on the analysis of a body of interviews with Ukrainian academics in forced migration and their Polish colleagues who were directly involved in aiding Ukrainians. The interviews were collected as part of the oral history project “‘Moving West’: Ukrainian Academics in Conditions of Forced Migration (2014-2023).” The authors focus on several main themes: Ukrainian migrants’ decision to leave the country and Polish respondents’ decision to get involved in helping Ukrainian refugees (the moment of‘challenge’), making sense of the new reality (the moment of the ‘meeting of two cultures’), adaptation to the new conditions, and reflection on the experience gained (the moment of ‘construction of specific strategies of behavior’).The authors consider the forced migration of Ukrainian academics to Poland caused by the Russian-Ukrainian War, particularly the expansion of communication between the Ukrainian and Polish academic communities and the experience gained in this process. The study is based on the analysis of a body of interviews with Ukrainian academics in forced migration and their Polish colleagues who were directly involved in aiding Ukrainians. The interviews were collected as part of the oral history project “‘Moving West’: Ukrainian Academics in Conditions of Forced Migration (2014-2023).” The authors focus on several main themes: Ukrainian migrants’ decision to leave the country and Polish respondents’ decision to get involved in helping Ukrainian refugees (the moment of‘challenge’), making sense of the new reality (the moment of the ‘meeting of two cultures’), adaptation to the new conditions, and reflection on the experience gained (the moment of ‘construction of specific strategies of behavior’)
The roles of structural variability and amphiphilicity of TMC278/rilpivirine in mechanisms of HIV drug resistance avoidance and enhanced oral bioavailability
No full textNon-nucleoside reverse transcriptase inhibitors (NNRTIs) are small hydrophobic drug molecules that bind to a hydrophobic pocket of the HIV-1 reverse transcriptase (RT). A number of molecules from diarylpyrimidine (DAPY) class of NNRTIs have exceptional inhibitory properties against a broad range of known drug-resistant viral strains of HIV-1 and good oral bioavailability in humans. Biophysical, structural, and computational methods were applied to study DAPY NNRTIs with differing RT inhibitory and bioavailability properties with a goal to define the mechanisms by which the dual success of the selected DAPY NNRTIs is achieved.
Exceptional bioavailability properties of selected DAPY NNRTIs were hypothesized to stem from their ability to form self-formulated spherical drug aggregates, ~60 nm in diameter, that are trafficked from the gastrointestinal tract into systemic circulation through a lymphatic uptake pathway. Using dynamic light scattering (DLS) and electron microscopy (EM), formation of drug aggregates was demonstrated. Drug aggregation was determined to be surfactant independent. Based on this observation, it was hypothesized that the drug molecules were able to achieve surface-active properties. Using X-ray crystallography and all atom MD simulations of the drug aggregate/water interface it was determined that amphiphilic properties of the selected DAPY NNRTI molecules depend on the availability of the protonation site at the pyrimidine ring and structural variability of the drug molecules at the linker moieties.
Ability of the late phase DAPY NNRTI drug molecules to inhibit the broad range of drug-resistant HIV-1 mutants has been previously linked to the ability of the molecules to sample multiple binding modes within the binding pocket of HIV-1 RT (Das et al., 2004). Using computational methods, conformational sampling by TMC278 (a DAPY NNRTI in multiple Phase III trials) in the pocket of the wild-type and the mutant NNRTI-binding pocket (NNIBP) was evaluated. Results of this work support the concept that structural variability is important in overcoming drug resistance mechanisms.
We propose that the implementation of drug aggregation testing and the evaluation of torsional flexibility of highly hydrophobic compounds in the context of the lead identification strategies will allow for better selection of potent and orally bioavailable hydrophobic drug candidates.Ph.D.Includes bibliographical references (139-146)by Yulia Frenke
Scanning tunneling microscopy and spectroscopy of topological materials and heterostructures in thin films and devices
No full textThis dissertation reports the results of scanning tunneling microscopy experiments probing the physics of thin films of topological materials. A 3D topological insulator Bi2Te3 and a 2D topological insulator WTe2, grown epitaxially, are studied with atomic resolution, and their physics is probed using in-situ back gating. The development of the back-gating process in a scanning tunneling microscope is one of the main results of this work and is reported in detail. The band structure of the monolayer WTe2 is observed to be drastically changing upon the application of electric field through the back gate. The complex effect of the gate-induced electric field on monolayer WTe2 is explored and discussed. A study of the spatial extent of 1D edge states of WTe2 is presented. A new process combining nanopatterned superconductors and topological materials is proposed and implemented. The proposed geometry in devices suitable for scanning tunneling microscopy studies opens up many new possibilities to explore the proximity effect in topological materials for future Majorana platform realization.Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2022-05-01The student, Yulia Maximenko, accepted the attached license on 2020-04-02 at 03:39.The student, Yulia Maximenko, submitted this Dissertation for approval on 2020-04-02 at 03:46.This Dissertation was approved for publication on 2020-04-06 at 14:22.DSpace SAF Submission Ingestion Package generated from Vireo submission #14932 on 2020-08-25 at 17:39:50Made available in DSpace on 2020-08-27T00:49:52Z (GMT). No. of bitstreams: 2
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APHERP symposium session IV : Higher education, job opportunities and transgenerational inequality
No full textPresented Titles: Massification and Transnationalisation of Higher Education: Challenges for Graduate Employment and Transgenerational Inequality in China [Authors: Joshua Ka-ho Mok; Guo-guo Ke; Tian Zhen] Expanding Higher Education during Economic Downturns: Why China’s Lessons are Hard to Learn From? [Authors: Wing-kit Chan; Jiarun Li] Multiple Factors Affecting Graduate Employability: What Implications for Graduates? [Authors: Yuzhuo Cai; Yulia Shumilova] Graduate Employability and Labour Market Relevance of Norwegian Higher Education: Perspectives from Students [Author: Dian Liu
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