1,765,138 research outputs found

    25.18 KC-135, cockpit

    No full text
    This image reflects a view of the cockpit in KC-135, also known as the Vomit Comet

    Determinação do coeficiente de cultura (KC) e evapotranspiração da cultura do alho na região do planalto catarinense.

    Full text link
    Projeto acadêmico (graduação) - Universidade Federal de Santa Catarina. Campus Curitibanos. Ciências Rurais.O coeficiente de cultura (Kc) associado a evapotranspiração de referência (ETo) estima a evapotranspiração da cultura. Esses dados são de extrema importância para um bom manejo de irrigação melhorando aspectos, como o consumo de água e a produtividade do alho. O projeto tem por objetivo determinar o coeficiente de cultura para a utilização desses dados no controle de irrigação. O coeficiente de cultura será determinado através de uma relação da evapotranspiração da cultura (ETc) e da evapotranspiração de referência (ETo), estimadas pelos métodos de tanque lisímetro para a ETc e pela equação de Penman-Monteith e tanque classe A para a Eto. Espera-se construir a curva do coeficiente de cultura determinando a duração dos estágios de desenvolvimento da cultura e o valor do Kc para cada fases, melhorando assim o manejo de irrigação na produção do alho, diminuindo os impactos ambientais e melhorando a produtividade da cultura

    25.26 KC-135 funnel test, in parabola

    No full text
    This image reflects a view of the KC-135 funnel test, in parabola

    kc-lab/dms2dfe: dms2dfe: Comprehensive Workflow for Analysis of Deep Mutational Scanning Data

    No full text
    <code>dms2dfe</code> <p><a href="https://travis-ci.org/rraadd88/dms2dfe"></a> <a href="https://pypi.python.org/pypi/dms2dfe"></a></p> Full documentation: <a href="http://kc-lab.github.io/dms2dfe/v1.0.6/html/">http://kc-lab.github.io/dms2dfe/v1.0.6/html/</a> Publication: dms2dfe: Comprehensive Workflow for Analysis of Deep Mutational Scanning Data Rohan Dandage, Kausik Chakraborty. <a href="http://joss.theoj.org/papers/f1a6726384232ad95bf3566ed95b6142"></a&gt

    KC-Adressbuch

    No full text
    KC-ADRESSBUCH KC-Adressbuch (Public Domain

    KC-180‑2 Exerts Anti-SCLC Effects via Dual Inhibition of Tubulin Polymerization and Src Signaling

    No full text
    In this study, a series of N-benzyl-2-(5-phenylpyridin-2-yl) acetamide-based derivatives were successfully designed and synthesized as anti-cancer agents. KC-180-2 was screened as a potentially leading compound with dual mechanisms of action: Src signaling and tubulin polymerization inhibition. It efficiently suppressed the proliferation of five cancer cell lines (MDA-MB-231, H446, SKOV-3, HepG2, and HT29), with IC50 values ranging from 5 to 188 nM, especially small-cell lung cancer (SCLC) cells (IC50, 5 nM). Correspondingly, it exerted a significant therapeutic effect on the H446 small-cell lung cancer xenograft model, significantly reducing the volume of tumors without obvious toxicity. Mechanistically, this compound significantly inhibited the polymerization of purified tubulin in vitro, inducing G2/M cell cycle arrest and binding to the kinase catalytic domain of the Src protein, which reduced the phosphorylation of Src. Thus, KC-180-2 is a potential lead compound for the further development of a new anti-tumor drug against SCLC

    On minimal strongly KC-spaces

    Full text link
    summary:In this article we introduce the notion of strongly KC{\rm KC}-spaces, that is, those spaces in which countably compact subsets are closed. We find they have good properties. We prove that a space (X,τ)(X, \tau ) is maximal countably compact if and only if it is minimal strongly KC{\rm KC}, and apply this result to study some properties of minimal strongly KC{\rm KC}-spaces, some of which are not possessed by minimal KC{\rm KC}-spaces. We also give a positive answer to a question proposed by O. T. Alas and R. G. Wilson, who asked whether every countably compact KC{\rm KC}-space of cardinality less than cc has the FDS{\rm FDS }-property. Using this we obtain a characterization of Katětov strongly KC{\rm KC}-spaces and finally, we generalize one result of Alas and Wilson on Katětov-KC{\rm KC} spaces

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Minimální KC prostory

    No full text
    Spaces, in which each compact subset is closed are called, KC spaces (we do not require any separation axioms). Obviously every Hausdorff space is KC and every KC space is T1. This thesis answers the question, whetever every KC space, which has no strictly weaker KC topology, is necessary compact. In the year 2002 T. Vidalis proved that every such space is countably compact, however his proof contains an error. The same problem was affirmatively solved in 2007 by A. Bella and C. Constantini
    corecore