291 research outputs found
Reply to Letter to the Editor: Intra-individual randomised comparison of gadobutrol 1.0 M versus gadobenate dimeglumine 0.5 M in patients scheduled for preoperative breast MRI
[No abstract available
Reply to Letter to the Editor: Intra-individual randomised comparison of gadobutrol 1.0 M versus gadobenate dimeglumine 0.5 M in patients scheduled for preoperative breast MRI
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Biological Control of Fusarium Crown and Root Rot of Wheat by Streptomyces Isolates – It’s Complicated
Intra-individual randomised comparison of gadobutrol 1.0 M versus gadobenate dimeglumine 0.5 M in patients scheduled for preoperative breast MRI
To demonstrate non-inferiority of gadobutrol versus gadobenate dimeglumine by intra-individually comparing 0.1 mmol/kg body weight doses for contrast-enhanced breast magnetic resonance imaging (MRI) and prospectively evaluating lesion detection and characterisation in a multicentre trial. Two identical breast MRI examinations were performed in 72 patients with biopsy-proven breast cancer, separated by 1-7 days. Gadobutrol 1.0 M or gadobenate 0.5 M were administered in a randomised order. Lesion detection and characterisation were performed by two independent blinded readers. Lesion tracking, which compared on-site readings and histology from surgery or biopsy, was performed by a third reader. Differences in lesion detection and characterisation were compared between the two contrast agents. Among 103 lesions, 96 were malignant and 7 were benign. No difference in lesion detection was identified between the contrast agents (82.33 % for gadobutrol, 81.60 % for gadobenate). Assessment of sensitivity in lesion characterisation and Breast Imaging Reporting and Data Systems showed no difference between gadobutrol (92.63 %) and gadobenate (90.53 %). Regarding morphology, there was more non-focal enhancement for gadobutrol than for gadobenate (P = 0.0057). Non-inferiority of gadobutrol compared with gadobenate was demonstrated for breast lesion detection and sensitivity in lesion characterisation in breast MRI. aEuro cent Contrast-enhanced magnetic resonance imaging is now widely used for breast problems. aEuro cent Lesion detection in breast MRI differs according to the contrast agent. aEuro cent Thus we compared gadobutrol 1 M with gadobenate dimeglumine 0.5 M. aEuro cent Gadobutrol was non-inferior to gadobenate dimeglumine for detecting and characterising malignant lesions
Targeted violence: a review of six school shootings and implications for school counselors
Includes bibliographical references
European society of urogenital radiology (ESUR) guidelines: MR imaging of pelvic endometriosis
Endometriosis is a common gynaecological condition of unknown
aetiology that primarily affects women of reproductive
age. The accepted first-line imaging modality is pelvic ultrasound.
However, magnetic resonance imaging (MRI) is increasingly
performed as an additional investigation in complex cases and for surgical planning. There is currently
no international consensus regarding patient preparation, MRI
protocols or reporting criteria. Our aim was to develop clinical
guidelines for MRI evaluation of pelvic endometriosis based
on literature evidence and consensus expert opinion. This
work was performed by a group of radiologists from the European Society of Urogenital Radiology (ESUR), experts in
gynaecological imaging and a gynaecologist expert in methodology.
The group discussed indications for MRI, technical
requirements, patient preparation, MRI protocols and criteria
for the diagnosis of pelvic endometriosis on MRI. The expert
panel proposed a final recommendation for each criterion
using Oxford Centre for Evidence Based Medicine
(OCEBM) 2011 levels of evidence.info:eu-repo/semantics/publishedVersio
Staging of endometrial cancer with MRI: Guidelines of the European Society of Urogenital Imaging
Contains fulltext :
81481.pdf (Publisher’s version ) (Closed access
Abnormal carbonate diagenesis in Holocene-Late Pleistocene sapropel-associated sediments from the Eastern Mediterranean; evidence from Emiliania huxleyi coccolith morphology
In studying the Holocene–late Pleistocene record of the Eastern Mediterranean, considerable Emiliania huxleyi size/shape variation not clearly assignable to primary or secondary calcification was observed. Accordingly, different morphotypes were distinguished by light microscope (LM).
A subsequent scanning electron microscope (SEM) analysis of selected samples has indicated that Emiliania huxleyi coccoliths are variably affected by carbonate diagenesis in these sediments. A series of diagenetic stages were qualitatively defined, comprising well-preserved specimens, three overgrowth (OG1 to OG3) and one etching (E1) stage. Comparing SEM and LM observations, a tentative correlation between the E. huxleyi calcified LM-morphotypes and E. huxleyi SEM-overgrowth stages is proposed here.
Our study not only indicates that Emiliania huxleyi coccoliths are strongly influenced by carbonate diagenesis, but also that they show effects of carbonate precipitation and dissolution much more clearly than other coccoliths. The relative abundances of the different LM-morphotypes were used to define an E. huxleyi overgrowth index (EXO) that qualitatively estimates carbonate precipitation/dissolution on coccoliths in this sediment. This resulted in definition of five “Diagenetic” intervals (D1 to D5). Deposition of sapropel S1 was a time of good preservation with variable dissolution and no overgrowth of E. huxleyi coccoliths, whereas calcite overgrowth was high during the Last Glacial Maximum (LGM) and interglacial period and, to a lesser extent, during the Younger Dryas and through the last 5 ka
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