114 research outputs found
Theoretical studies of the historical development of the accounting discipline: a review and evidence
No full textMany existing studies of the development of accounting thought have either been atheoretical or have adopted Kuhn's model of scientific growth. The limitations of this 35-year-old model are discussed. Four different general neo-Kuhnian models of scholarly knowledge development are reviewed and compared with reference to an analytical matrix. The models are found to be mutually consistent, with each focusing on a different aspect of development. A composite model is proposed. Based on a hand-crafted database, author co-citation analysis is used to map empirically the entire literature structure of the accounting discipline during two consecutive time periods, 1972–81 and 1982–90. The changing structure of the accounting literature is interpreted using the proposed composite model of scholarly knowledge development
Fear of fiction: the authorial response to realism in selected works by Swift, Defoe, and Richardson
No full textIf Mrs. Whitehouse produced a pornographic play, it would arouse enormous interest, mainly because of Mrs. Whitehouse’s well known views on pornography. It is an ancient fact of English Literature that two of the best known pioneers of the English realistic novel, Daniel Defoe and Samuel Richardson, were Puritans. And there is an almost equally ancient critical tradition which traces the easy path of Puritan literature, in combination with other cultural forces, towards the production of realistic fiction. The central argument of this thesis is that there was no such easy path. Puritan autobiography was unrealistic in its very nature, while Puritan feeling towards fiction was hostile, with realistic, or verisimilar fiction provoking most hostility because the most deceitful. Thus the writing of a realistic novel was a radical departure for the Puritan, and one that was fraught with tension. It is this tension, or fear of fiction, and its effects on work of the two Puritan novelists, and that odd Anglican Jonathan Swift, that is the subject of this thesis. Swift joins Defoe and Richardson as an author with a special relationship with Defoe, and himself closer to a fearful anti- mimetic "tradition" than the comic tradition in which he is usually placed alongside Fielding and Sterne. Selected works of the three authors reveal their struggle with the intense problems that realism created for them, and their eventual 'solutions'. Hence by the time that Dr. Johnson made his famous critical statement against the fearful potential of realism in his fourth Rambler [31 March 1750), he was actually formalising material that had been well examined in the fiction under discussion, rather than beating an original critical path in response to Fielding's supposedly 'new' verisimilar form
Convocation programs - 1968
No full textApril 26-27, 1968Includes list of graduates, baccalaureate service and commencement exercisesFor AODA accommodation, including help with reading this content, please contact [email protected]. Baccalaureate service: Organ Prelude “Preludio” (Bach) – “Violine” Handel / Warren E. Adams, M.Mus. Associate Professor of Music – Processional “God of Our Fathers” Warren – The Invocation / Terrance L. Tiessen, B.Th., M.A., Lecturer in Philosophy and Greek – Hymn “Praise, My Soul, the King of Heaven” Lyte, Goss / Rev. Wm. R. Foster, B.A., B.D., Th.D., Academic Dean and Acting President – Scripture Reading Rom. 12:1-12 / Michael Johnson Class of ’68 – Musical Selection “The Lord is My Light” Buck / Christine Unruh and David Gast – Prayer / Rev. Wm. J. Wallace, B.A., M.Ed. Associate Professor of Missions – Words of Witness / Faye Nutt and Trevor Baetz Class of ’68 – Hymn “Praise Ye the Lord, the Almighty” Neander – Presentation of Bible Society Award / Rev. Andrew Brndjar, Canadian Bible Society – Choral Selection “Sing and Rejoice” James / London College Chorale – Sermon / Rev. Stewart L. Boehmer, D.D., President, Toronto Bible College – Hymn “May the Mind of Christ, My Saviour” Wilkinson – Barham – Gould – The Benediction / Rev. Chas. W. Scott, B.R.E., M.A., Assistant Professor of Christian Education – Recessional “Lead On, O King Eternal” Smart – Organ Postlude “The Heavens Declare the Glory of God” Marcello – Jesus, Our Lord.2. Commencement Exercise: Organ Prelude “He Who Will Suffer God to Guide Him” Bach – Chorale Prelude “Nun preiset alle” Willan / Warren E. Adams, M.Mus. Associate Professor of Music – Processional “Pomp and Circumstance” Elgar – The Doxology – The Queen – The Invocation / Rev. Lambert Baptist, B.R.E., President, Alumni Association – Words of Witness / Faith Warman and Charles Congram Class of ’68 – Musical Selection “Hymn Dedication” arr. W.E. Adams / Student Body – Address / Hudson Taylor Armerding, M.A., Ph.D., President, Wheaton College – Choral Selection “Sun of My Soul” Martin / London College Chorale – Offertory “Adagio in a Minor” Sweelinck – Hymn “Soldiers of Christ, Arise” Elvey – Presentation of Awards / Rev. Kermit A. Ecklebarger, M.A., Dean of Students – Presentation of the Graduating Class / Elizabeth I. Wicks, B.R.E. Assistant Registrar – Awarding of Certificates, Diplomas and Degrees / Rev. Wm. R. Foster, B.A., B.D., Th.D. Academic Dean and Acting President – Dedicatory Prayer / Melvin L. Steinmann, Chairman, Board of Governors – School Hymn “Jesus, Our Lord” Macaulay – The Benediction / Rev. Donald A. Leggett, B.A., B.D., Th.M. Doctorandus, Associate Professor of Old Testament – The Hallelujah Chorus (Messiah” Handle / Augmented Chorale – Recessional “A Mighty Fortress is Our God” Luther – Organ Postlude “Introduction and Toccata in G Major” Walond – Soldiers of Christ, Arise – Graduates of 196
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
No full textElevated resting heart rate is associated with greater risk of cardiovascular disease and mortality. In a 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals, we identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci. Experimental downregulation of gene expression in Drosophila melanogaster and Danio rerio identified 20 genes at 11 loci that are relevant for heart rate regulation and highlight a role for genes involved in signal transmission, embryonic cardiac development and the pathophysiology of dilated cardiomyopathy, congenital heart failure and/or sudden cardiac death. In addition, genetic susceptibility to increased heart rate is associated with altered cardiac conduction and reduced risk of sick sinus syndrome, and both heart rate-increasing and heart rate-decreasing variants associate with risk of atrial fibrillation. Our findings provide fresh insights into the mechanisms regulating heart rate and identify new therapeutic targets
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
No full textGenetic factors have been implicated in stroke risk, but few replicated associations have been reported. We conducted a genome-wide association study (GWAS) for ischemic stroke and its subtypes in 3,548 affected individuals and 5,972 controls, all of European ancestry. Replication of potential signals was performed in 5,859 affected individuals and 6,281 controls. We replicated previous associations for cardioembolic stroke near PITX2 and ZFHX3 and for large vessel stroke at a 9p21 locus. We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10<sup>−11</sup>; odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28–1.57). All four loci exhibited evidence for heterogeneity of effect across the stroke subtypes, with some and possibly all affecting risk for only one subtype. This suggests distinct genetic architectures for different stroke subtypes
Literary representations of maternity in the eighteenth century
No full textThe primary concern of this thesis is the representation, in the eighteenth century, of mothers' bodies. It is also concerned with the treatment of domestic duties which were supposed a consequence of a woman's very nature. Throughout the first seven decades of the century, medical men and virtuosi demonstrated particular interest in the nature of physicality, and especially in women's bodies, pregnancy, and childbirth. 1 will be testing out a widely-held view that dissection and new anatomical findings regarding women's bodies produced a new idealisation of motherhood, and that this was immediately translated into lay-medical and related discourse, and was thus firmly established in middle-class culture by the end of the century. The relationship between primary medical and lay-medical literature raises several questions: my work asks whether lay-medical literature mirrored medical writing, and whether there was a direct translation of material from one to the other. Lay-medical texts for women are especially interesting. They offer an insight into precisely what examples of female nature and correspondingly 'natural' behaviour were intended for women readers. Representations of maternity in specific forms of writing which rely heavily upon women for subject matter are further extended in the second half of this study. 1 have focussed upon two genres, conduct literature and narrative fiction. Neither is conventionally associated with medical or lay-medical discourse, yet both have significant links with these. Conduct literature and narrative fiction have much to offer in this attempt to recover what women were being taught about their bodies and roles; both were concerned with what the body displays externally, and with corresponding ideas of 'naturalness'. Conduct literature for women was enjoying a period of growth and change, and has obvious, direct links with medical texts. Narrative fiction also had important links with medical writing, and 1 will describe these. The dissemination of medical representations of the maternal body was a process which contributed to a contradictory cultural sense of female identity
Children facing economic hardships in the United States
No full textThis paper helps document significant improvements in the child low-income rate as well as the significant decrease in the proportion of children who relied on public assistance in the United States during the 1990s. Many disadvantaged groups of children were less likely to live in poor or low-income families in the late 1990s than such children a decade earlier. The improvement in the child low-income rates of these disadvantaged groups was accompanied by a substantial increase in parental employment. However, parental employment appears to do less to protect children from economic hardship than it did a decade earlier. This paper shows that working families’ children in many disadvantaged social groups, especially groups in medium risk ranks--children in families with parents between ages 25 to 29, with parents who only had a high-school diploma, and in father-only families--suffered the largest increase in economic hardship. Our results indicate that the increased odds of falling below low-income lines among children in working families facing multiple disadvantaged characteristics and the increased proportion of these children in various subgroups of working families in the 1990s can help explain the increased economic hardship among subgroups in the medium risk ranks listed above. Finally, the paper also notes that the official measure of poverty tends to underestimate low-income rates.bootstrap, child poverty, employment, income, low income, poverty measure, welfare reform
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke
No full textGenome-wide association studies (GWAS) have not consistently detected replicable genetic risk factors for ischemic stroke, potentially due to etiological heterogeneity of this trait. We performed GWAS of ischemic stroke and a major ischemic stroke subtype (large artery atherosclerosis, LAA) using 1,162 ischemic stroke cases (including 421 LAA cases) and 1,244 population controls from Australia. Evidence for a genetic influence on ischemic stroke risk was detected, but this influence was higher and more significant for the LAA subtype. We identified a new LAA susceptibility locus on chromosome 6p21.1 (rs556621: odds ratio (OR) = 1.62, P = 3.9 × 10 -8) and replicated this association in 1,715 LAA cases and 52,695 population controls from 10 independent population cohorts (meta-analysis replication OR = 1.15, P = 3.9 × 10 -4; discovery and replication combined OR = 1.21, P = 4.7 × 10 -8). This study identifies a genetic risk locus for LAA and shows how analyzing etiological subtypes may better identify genetic risk alleles for ischemic stroke
Applicability of HCI Techniques to Systems Interface Design
No full textPhDThis thesis seeks to identify reasons why HCI techniques are unsuitable for application
in real world design projects. User-oriented systems design and evaluation require
that many considerations such as the psychology of users, the applications and
target tasks be born in mind simultaneously. A selection of influential HCI design
and evaluative techniques from HCI research literature are reviewed and characterised
in terms of their analytic scope.
Two studies of systems designers' approaches to user-oriented design and evaluation
were carried out in order to gain a clearer picture of the design process as it occurs
in applied and commercial projects. It was found that designers frequently lack
adequate information about users, carrying Out, at best, informal user-evaluations of
prototypes. Most notably HCI design and evaluative techniques, of the type common
in the literature, are not being used in applied and commercial design practice.
They seem to be complex, often limited in scope, and possessed of inadequate or
unrepresentative views of the design process within which they might be applied. It
was noted that design practice is highly varied with only a small number of common
goal directed classes of activity being identified. These together with observed
user-oriented information sources and design constraints provide a useful schema
for viewing applied and commercial design practice.
A further study of HCI specialists' practice in commercial environments was undertaken,
in order to identify particular user-oriented design approaches and HCI techniques
suitable for application in practice. The specialists were able to describe
desirable, and undesirable properties of the techniques they used which made it possible
to identify a list of specific desirable features for HCI techniques. A framework
for assessing applicability of HCI techniques was developed from the findings
of the thesis. This is demonstrated using an example project from the design studies
and may prove valuable in supporting design, evaluation, critiquing and selection of
HCI techniques
Church, state and society; the attitudes of John Keble, Richard Hurrell Froude and John Henry Newman. 1827-1845
No full textKeble, Froude and Newman's understanding of the Church in relationship to State and society is considered against an- eighteenth century background which, thanks partly to the Tractarians, has been painted in colours which portray Godlessness, belief in progress and the perfection of man with a tepid Church and a torpid religion willing onlookers. The Enlightenment was far more complicated than this caricature. Yet it is not always the accuracy of the picture but the supposed image which matters. In that sense, Keble, Froude and Newman shared the reaction of the Romantic Movement to what was seen as the prevailing Rationalist and Utilitarian spirit witnessed inside the Church by her powerful alliance with governments and political economists and outside by the united attacks from Roman Catholics, Radicals, Nonconformists and philosophers. Chapter 1 studies the political and social implications of The Christian Year, Keble's abhorrence of the 1832 Reform Bill and his sermon "National Apostasy". His views about Poor Law reform and the importance of Tradition are also considered. Froude's articles on "State Interference in Matters Spiritual", his influence upon the political and social outlook of Keble and Newman and the political significance of the posthumously published Remains are the themes of Chapter 2. In Chapter 3, Newman's opposition to Peel and Roman Catholic Emancipation in 1829, his attitude to the 1832 Reform Bill, his views on history in The Arians and the relationship of the Church to society are studied. His criticism of Peel in 1841, his views on change, development and progress between 1841 and 1845 and his final view as an Anglican of the Church as an imperial power are also considered. For Keble, Froude and Newman, the Church's mission to society was always spiritual with no thought of accommodation to the needs of the age. Saints are more important than reformers. The three figures studied upheld Tory paternalism in their concepts of the interrelationship between rich and poor and their detestation of democracy. Their understanding of the Church's relationship with the State, however, was different in that Keble was a critical orthodox thinker, Froude a radical catalyst and Newman a theoretician of profound development. They completely rejected the progressive spirit of Peelite Conservatism and brought to Toryism a powerful moral and spiritual temper, seen in Keble's perseverance in adversity, Froude's search for an alternative in Feudal times and Newman's advocacy of a transcendental, eternal and triumphant Orthodoxy and Orthopraxis
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