11 research outputs found
The political instrumentalization of professional football in Francoist Spain 1939-1975
No full textPhDThe objective of this thesis is to be the first systematic study of the
political instrumentalization of football in Francoist Spain from 1939
to 1975.
Seven separate and contrasting aspects of this political
instrumentalization may be isolated, and, accordingly, this thesis will
consist of a chapter examining each one of these seven aspects in turn.
After a first introductory chapter, Chapter Two will examine the
application of Fascist concepts to Spanish football. In the third
chapter, the questions of whether and to what extent football was used
by the Franco regime as a political soporific will be discussed. The
theme of Chapter Four is the lack of democracy within the structures of
the game, a situation that is alleged to have been deliberately imposed
by the regime in order to not create an uncomfortable comparison for
itself with the lack of national and local political democracy. The
poor working conditions of the footballers, which mirrored those of the
great majority of Spanish workers during the Franco period, are the
subject of Chapter Five. In the sixth Chapter, the political
significance of the presence in Francoist Spain of a group of refugee
players and coaches from Europe will be examined. The diplomatic
and ambassadorial significance of football, in particular of the
spectacular international triumphs of the Real Madrid club, will be
discussed in Chapter Seven. The political significance of football as a
focus for Basque and Catalan nationalist sentiment, in opposition to the
centralist Madrid regime, is the subject of Chapter Eight
(Re) pensando la negritud en la música popular puertorriqueña.
No full textThis article explores how Puerto Rican popular music constructs Blackness. The author examines how Afro Puerto Ricans interpret and represent their Blackness. Racialization in Afro Caribbean Diaspora is explored through the analysis of song lyrics and interviews to Black Puerto Rican musicians. Songs such as: Piel canela, El negro bembón, Las caras lindas, Tan bueno que era, Si Dios fuera negro, Carbonerito, Capullo y Sorullo and El africano have phrases and images that seem to reproduce the worst of racist discourse and, some of these lyrics, composed by Black Puerto Rican musicians, perpetuate racial stereotypes. Racial discourses operate from diverse registers and are complex productions of meaning. This article is intended to explain racialization as matrix for the production of meaning and a fundamental factor in the production of musical discourses that structure an imaginary of Afro Puerto Rican Blackness.Este artículo explora la manera en que se construye la negritud a través de la música popular puertorriqueña. Ausculta cómo los afropuertorriqueños interpretan y representan su negritud. Por medio del análisis de letras musicales y entrevistas a músicos puertorriqueños negros, se busca trazar un mapa sobre la racialización en esta diáspora africana del Caribe. Canciones como: Piel canela, El negro bembón, Las caras lindas, Tan bueno que era, Si Dios fuera negro, Carbonerito, Capullo y Sorullo y El africano contienen frases e imágenes que parecen reproducir lo peor del discurso racista. Algunas de estas letras, compuestas por músicos puertorriqueños negros, perpetúan los estereotipos de índole racial. Los discursos sobre raza operan desde diversos registros y son complicadas producciones de sentido. En fin, se intenta explicar cómo la racialización en tanto matriz de producción de sentidos, es factor fundamental en la producción de los discursos musicales que estructuran un imaginario de la negritud de los afroboricuas
Correction to: Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials
No full textCorrection to: European Journal of Clinical Pharmacology (2021) 77:1–12 https://doi.org/10.1007/s00228-020–02951-8 The article Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials, written by Farhad Pazan, Mirko Petrovic, Antonio Cherubini, Graziano Onder, Alfonso J. Cruz-Jentoft, Michael Denkinger, Tischa J. M. van der Cammen, Jennifer M. Stevenson, Kinda Ibrahim, Chakravarthi Rajkumar, Marit Stordal Bakken, Jean-Pierre Baeyens, Peter Crome, Thomas Frühwald, Paul Gallaghar, Adalsteinn Guðmundsson, Wilma Knol, Denis O’Mahony, Alberto Pilotto, Elina Rönnemaa, José Antonio Serra-Rexach, George Soulis, Rob J. van Marum, Gijsbertus Ziere, Alpana Mair, Heinrich Burkhardt, Agnieszka Neumann-Podczaska, Katarzyna Wieczorowska- Tobis, Marilia Andreia Fernandes, Heidi Gruner, Dhayana Dallmeier, Jean-Baptiste Beuscart, Nathalie van der Velde and Martin Wehling, was originally published electronically on the publisher’s internet portal on 07 August 2020 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on 14 May 2021 to © The Author(s) 2021 and the article is forthwith distributed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creat iveco mmons. org/ licen ses/ by/4.0. The Original article has been corrected
Crackin' the code of post-race: post-1980s novels and post-race discourses
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Programa de Pós-Graduação em Inglês: Estudos Linguísticos e Literários, Florianópolis, 2013.Abstract : The last decades has seen a shift in racial thought in the U.S. The discourses vary from the statement that the U.S. has moved beyond race to the post-racial neoliberalist discourse in which 'essential' identities are fragments of a social past and its continuance has the function of renewing race and racism. As these discourses gain ground in the U.S. society, the issue of fighting racism becomes more slippery. The present investigation analyzes the meanings attached to the rebirth of novels that deals with the concept of passing for white in this period and its relation with the fragmentation of the color line. More specifically, the aim of this dissertation is to unveil the forms through which No Telephone to Heaven, Caucasia, and The Girl Who Fell from the Sky respond to the discourses of racial liberalism and Critical Realism. Drawing upon Santiago?s concept of in-betweenness and Butler's concept of performativity, this dissertation sought to analyze the novels chosen as rich sources of insight about the changing racial thought in the U.S.As últimas décadas registraram uma mudança no pensamento racial nos Estados Unidos. Os discursos variam da afirmação de que os Estados Unidos transcendeu a questão racial ao discurso neoliberalista pós-racial que considera identidades 'essenciais' como fragmentos de um passado social e sua continuação apenas renova os conceitos de raça e racismo. A medida que esses discursos se tornam dominantes nos Estados Unidos, a questão do combate ao racismo se torna mais incerta. A presente investigação analisa os significados ligados ao reaparecimento de romances que lidam com o conceito de 'passar por branco' neste período e sua relação com a fragmentação da ?color line?. Mais especificamente, o objetivo deste estudo é investigar a forma que No Telephone to Heaven, Caucasia, and The Girl Who Fell from the Sky respondem aos discursos de liberalismo racial e Realismo Crítico. Com base no conceito de ?entre-lugar? de Santiago e o conceito de performatividade de Butler, esta tese procurou analisar as novelas escolhidas como fontes ricas de compreensão do pensamento racial nos Estados Unidos
A flagellation by Joan Reixach in a private collection: new documents and considerations on the collaboration Jacomart-Reixach
No full text[EN] The attribution to Joan Reixach of a panel representing the Flagellation, has allowed us to contribute unpublished
news concerning its author and his occasional professional links with Jacomart. This tacit relationship is now
demonstrated by a new document of 1449, which would explain the contractual and stylistic proximity of some
of their works.[ES] La atribución a Joan Reixach de una tabla con la Flagelación, nos ha permitido aportar noticias inéditas en torno a su
autor y a los lazos profesionales que pudieron unirle en ocasiones con Jacomart. Una asociación tácita demostrada
documentalmente con una nueva noticia fechada en 1449 que explicaría la proximidad estilística y contractual de
algunas de sus obras.Este artículo se incluye dentro del trabajo del Proyecto de Investigación I+D+I del Ministerio de Ciencia e Innovación
titulado: La configuración de la Pintura Mediterránea del primer Renacimiento en la Corona de Aragón (c.1440-
1525). Problemas de pintura (HAR2009-07740; en el que participan los autores de este artículo, Universitat de Lleida).
Así como del Grup de Recerca Consolidat reconocido por el Departament d’Innovació, Universitats i Empresa de la
Generalitat de Catalunya: “Art i Cultura d’Època Moderna” (ACEM) de la Universitat de Lleida (2009 SGR 348).Company Climent, J.; Franco, B.; Puig, I.; Aliaga Morell, JI.; Rusconi, S. (2012). Una Flagelación de Joan Reixach de colección particular. Nuevos documentos y consideraciones sobre el binomio Jacomart-Reixach. Archivo Español de Arte. LXXXV(340):363-373. https://doi.org/10.3989/aearte.2012.v85.i340.520S363373LXXXV340Benito Doménech, Fernando, "Evocaciones flamencas en los primitivos valencianos", en Benito Doménech, Fernando (comisario), La clave flamenca en los primitivos valencianos, cat. exp., Valencia, Generalitat Valenciana, 2001, pp. 23-62.Ferre, Josep, "Joan Reixac, autor de dues obres del cercle Jacomart-Reixac", en Actes del Primer Congrés d'Estudis de la Vall d'Albaida, Valencia, Diputació de València, 1997, pp. 311-320.Gómez-Ferrer, Mercedes, "Jacomart: revisión de un problema historiográfico", en Hernández, Lorenzo (coord.), De pintura valenciana (1400-1600), Alicante, Instituto Alicantino de Cultura Juan Gil-Albert, 2006, pp. 71-100.González, Mariano, "Joan Reixac o Pere Joan Reixac: Santa Ana, la Virgen y el Ni-o", en Ruiz, Francesc (comisario), La pintura gòtica hispanoflamenca. Bartolomé Bermejo i la seva època, cat. exp., Barcelona, MNAC y Museo de Bellas Artes de Bilbao, 2003, pp. 214-219.Serrano, Manuel, "Documentos relativos a la pintura de Aragón durante los siglos XIV y XV", en Revista de Archivos, Bibliotecas y Museos, 34, 1916, pp. 455-485.Terés, Maria Rosa, "Llorenç Reixac, escultor de la catedral de Barcelona", Lambard, vol. III, 1987, pp. 171-185.Tormo, Elías, "Los pintores cuatrocentistas: Juan Rexach", Cultura Espa-ola, XI, 1908 pp. 1064-1079.Tormo, Elías, Jacomart y el arte hispano-flamenco cuatrocentista, Madrid, Centro de Estudios Históricos, 1913
Epistasis, physical capacity-related genes and exceptional longevity: FNDC5 gene interactions with candidate genes FOXOA3 and APOE
No full textBackground: Forkhead box O3A (FOXOA3) and apolipoprotein E (APOE) are arguably the strongest gene candidates to influence human exceptional longevity (EL, i.e., being a centenarian), but inconsistency exists among cohorts. Epistasis, defined as the effect of one locus being dependent on the presence of 'modifier genes', may contribute to explain the missing heritability of complex phenotypes such as EL. We assessed the potential association of epistasis among candidate polymorphisms related to physical capacity, as well as antioxidant defense and cardiometabolic traits, and EL in the Japanese population. A total of 1565 individuals were studied, subdivided into 822 middle-aged controls and 743 centenarians. Results: We found a FOXOA3 rs2802292 T-allele-dependent association of fibronectin type III domain-containing 5 (FDNC5) rs16835198 with EL: the frequency of carriers of the FOXOA3 rs2802292 T-allele among individuals with the rs16835198 GG genotype was significantly higher in cases than in controls (P<0.05). On the other hand, among non-carriers of the APOE 'risk' ε4-allele, the frequency of the FDNC5 rs16835198 G-allele was higher in cases than in controls (48.4% vs. 43.6%, P<0.05). Among carriers of the 'non-risk' APOE ε2-allele, the frequency of the rs16835198 G-allele was higher in cases than in controls (49% vs. 37.3%, P<0.05). Conclusions: The association of FDNC5 rs16835198 with EL seems to depend on the presence of the FOXOA3 rs2802292 T-allele and we report a novel association between FNDC5 rs16835198 stratified by the presence of the APOE ε2/ε4-allele and EL. More research on 'gene*gene' and 'gene*environment' effects is needed in the field of EL. © 2017 The Author(s).Universidad Autónoma de Chil
Aproximación a la identificación del sexo biológico del autor en columnas de opinión escritos en español mediante rasgos estilísticos
No full textLa lingüística forense ha centrado su estudio en la atribución de autoría y la detección de plagio. No obstante, el auge de los medios digitales ha generado un interés creciente en identificar características específicas de los autores, como el sexo biológico, especialmente en textos anónimos vinculados con la suplantación de identidad, amenazas y terrorismo. Aunque en las últimas dos décadas han surgido investigaciones al respecto, la mayoría se han centrado en el inglés y el español peninsular. Este estudio propone un análisis para determinar el sexo biológico del autor de textos en español desde la lingüística forense. A partir de un corpus de artículos de opinión, se examinan rasgos lingüísticos clave para la elaboración de perfiles que faciliten la identificación del género, empleando análisis de corpus y estadística lingüística.Forensic linguistics has focused its study on authorship attribution and plagiarismdetection. However, the rise of digital media has generated a growing interest in identifyingspecificcharacteristics of authors, such as biological sex, especially in anonymous texts linkedtoimpersonation, threats and terrorism. Although research has emerged in the last two decades, most of it has focused on English and peninsular Spanish. This study proposes an analysistodetermine the biological sex of the author of Spanish texts from the perspective of forensiclinguistics. Based on a corpus of opinion articles, key linguistic features are examinedfor theelaboration of profiles that facilitate gender identification, using corpus analysis and linguisticstatistics.PregradoFilólogo(a) Hispanist
Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty : a systematic review of randomized controlled trials
No full textBackground Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven in older people with clinically manifest frailty.
Methods A literature search was performed in Medline to detect prospective randomized controlled trials (RCTs) testing the effects of pharmacological interventions or medication optimization in older frail adults on comprehensive frailty scores or partial aspects of frailty that were published from January 1998 to October 2019.
Results Twenty-five studies were identified, 4 on comprehensive frailty scores and 21 on aspects of frailty. Two trials on
comprehensive frailty scores showed positive results on frailty although the contribution of medication review in a multidimensional approach was unclear. In the studies on aspects related to frailty, ten individual drug interventions showed improvement in physical performance, muscle strength or body composition utilizing alfacalcidol, teriparatide, piroxicam, testosterone, recombinant human chorionic gonadotropin, or capromorelin. There were no studies examining negative effects of drugs on frailty.
Conclusion So far, data on a causal relationship between drugs and frailty are inconclusive or related to single-drug interventions on partial aspects of frailty. There is a clear need for RCTs on this topic that should be based on a comprehensive, internationally consistent and thus reproducible concept of frailty assessmen
The role of emerin and LEM domain proteins in nuclear envelope assembly and cytoskeleton organisation
No full textThe nuclear envelope (NE) plays a fundamental role in the cell by separating nuclear from cytoplasmic activities, and mutations in NE proteins have been associated with a diverse array of diseases. In the present study the Xenopus cell-free system was used to investigate the function of the inner nuclear membrane protein, emerin, which is associated with the Emery-Dreifuss muscular dystrophy (X-EDMD).Initially, the order and dynamics of NE assembly in Xenopus egg extracts have been investigated. Using a panel of antibodies it was shown that NE assembly proceeds by the ordered recruitment of two membrane populations, Nuclear Envelope Precursor vesicles -A and -B (NEP-A and NEP-B), to chromatin. As shown by immunofluorescence NEP-B vesicles, together with nucleoporins (Nups), appear first around chromatin at about ten minutes after initiation of NE assembly while NEP-A vesicles appear at a later stage, at about twenty minutes. To investigate the role of different emerin domains in this process, four human emerin peptides consisting of amino acids (aa) 1-70, 1-176, 1-220 and 73-180 were added individually to Xenopus nuclear assembly reactions at different concentrations and the effect on nuclear vesicle recruitment and NPC formation was monitored. Immunofluorescence analysis showed that peptides containing the LEM domain of emerin interfere with a correct NE assembly by inhibiting chromatin decondensation and recruitment of membranes to chromatin. This inhibitory effect was shown to be exerted mainly on NEP-A membranes and on Nup62 and Nupl53. By the use of two antibodies, raised against the LEM domain of human emerin and LAP2ß, two proteins of 30 and 36 kD, respectively, were identified in Xenopus. Both proteins were shown to reside in the NEP-A membrane population providing an explanation for the preferential inhibition of NEP-A recruitment to chromatin by exogenously added LEM domain containing emerin peptides. To further investigate whether the domain specific inhibitory effects of emerin on nuclear assembly correlate with specific interacting proteins, co-precipitation experiments were performed to identify emerin binding proteins in the Xenopus cytosol. From these experiments ß -tubulin was identified as a protein able to interact with emerin peptides 1-70 and 73-180. Staining of X-EDMD cells, which lack emerin, with a ß -tubulin antibody revealed no alterations in the organisation of the microtubule (MT) network. The most prominent effect of emerin mutations regarding MTs was the position of the Microtubule Organising Centre (MTOC) relative to the NE. Staining for the centrosomal protein pericentrin revealed a mis-localisation of the MTOC away from the NE in X-EDMD cell lines at distances at least double compared to control cells
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
No full textInterindividual clinical vari-ability is vast in humans infected withsevere acute respiratory syndrome corona-virus 2 (SARS-CoV-2), ranging from silent in-fection to rapid death. Three risk factors forlife-threatening coronavirus disease 2019(COVID-19) pneumonia have been identified—being male, being elderly, or having othermedical conditions—but these risk factorscannot explain why critical disease remainsrelatively rare in any given epidemiologicalgroup. Given the rising toll of the COVID-19pandemic in terms of morbidity and mortality,understanding the causes and mechanisms oflife-threatening COVID-19 is crucial.The Laboratory of Human Genetics of Infectious Diseases is supported by the Howard Hughes Medical Institute, The Rockefeller University, the St. Giles Foundation, the National Institutes of Health (NIH) (R01AI088364), the National Center for Advancing Translational Sciences (NCATS), NIH Clinical and Translational Science Award (CTSA) program (UL1 TR001866), a Fast Grant from Emergent Ventures, the Mercatus Center at George Mason University, the Yale Center for Mendelian Genomics and the GSP Coordinating Center funded by the National Human Genome Research Institute (NHGRI) (UM1HG006504 and U24HG008956), the French National Research Agency (ANR) under the Investments for the Future program (ANR-10-IAHU-01), the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence (ANR-10-LABX-62-IBEID), the French Foundation for Medical Research (FRM) (EQU201903007798), the FRM and ANR GENCOVID project (ANRS-COV05), the Square Foundation, Grandir – Fonds de solidarité pour l’enfance, the SCOR Corporate Foundation for Science, the Institut Institut National de la Santé et de la Recherche Médicale (INSERM), and the University of Paris. Samples from San Raffaele Hospital were obtained through the Covid-BioB project and by healthcare personnel of San Raffaele Hospital, San Raffaele Telethon Institute for Gene Therapy (SR-TIGET) clinical laboratory and clinical research unit, funded by the Program Project COVID-19 OSR-UniSR and Fondazione Telethon. The French COVID Cohort Study Group was sponsored by INSERM and supported by the REACTing consortium and by a grant from the French Ministry of Health (PHRC 20-0424). The Cov-Contact Cohort was supported by the REACTing consortium, the French Ministry of Health, and the European Commission (RECOVER WP 6). The Milieu Intérieur Consortium was supported by the French Government’s Investissement d’Avenir program, Laboratoire d’Excellence Milieu Intérieur grant (ANR-10-LABX-69-01) (primary investigators: L.Q.-M. and D.Du.). The Simoa experiment was supported by the PHRC-20-0375 COVID-19 grant “DIGITAL COVID” (primary investigator: G.G.). S.G.T. is supported by a Leadership 3 Investigator Grant awarded by the National Health and Medical Research Council of Australia and a COVID19 Rapid Response Grant awarded by UNSW Sydney. C.R.-G. and colleagues were supported by the Instituto de Salud Carlos III (COV20_01333 and COV20_01334, Spanish Ministry of Science and Innovation RTC-2017-6471-1; AEI/FEDER, UE) and Cabildo Insular de Tenerife (CGIEU0000219140 and “Apuestas científicas del ITER para colaborar en la lucha contra la COVID-19”). S.T.-A. and A.B. were supported by ANR-20-COVI-0064 (primary investigator: A.Be.). This work is supported by the French Ministry of Health “Programme Hospitalier de Recherche Clinique Inter regional 2013,” by the Contrat de Plan Etat-Lorraine and FEDER Lorraine, and by a public grant overseen by the French National Research Agency (ANR) as part of the second Investissements d’Avenir program FIGHT-HF (reference no. ANR-15-RHU-0004) and by the French PIA project “Lorraine Université d’Excellence” (reference no. ANR-15-IDEX-04-LUE) (45); and biobanking is performed by the Biological Resource Center Lorrain BB-0033-00035. This study was supported by the Fonds IMMUNOV, for Innovation in Immunopathology; by a grant from the Agence National de la Recherche (ANR-flash Covid19 “AIROCovid” to F.R.-L.); and by the FAST Foundation (French Friends of Sheba Tel Hashomer Hospital). Work in the Laboratory of Virology and Infectious Disease was supported by NIH grants P01AI138398-S1, 2U19AI111825, and R01AI091707-10S1; a George Mason University Fast Grant; and the G. Harold and Leila Y. Mathers Charitable Foundation. The Amsterdam UMC Covid-19 Biobank was supported by grants from the Amsterdam Corona Research Fund, the Dr. C.J. Vaillant Fund, and the Netherlands Organization for Health Research and Development [ZonMw; NWO-Vici-Grant (grant no. 918·19·627 to D.v.d.B.)]. This work was also supported by the Division of Intramural Research of the National Institute of Dental Craniofacial Research and the National Institute of Allergy and Infectious Diseases, National Institutes of Health, and by Regione Lombardia, Italy (project “Risposta immune in pazienti con COVID-19 e comorbidita”). The opinions and assertions expressed herein are those of the author(s) and do not necessarily reflect the official policy or position of the Uniformed Services University or the Department of Defense. J.H. holds an Institut Imagine M.D.-Ph.D. fellowship from the Fondation Bettencourt Schueller. J.R. is supported by the INSERM Ph.D. program (“poste d’accueil Inserm”). P.Ba. was supported by the French Foundation for Medical Research (FRM, EA20170638020) and the M.D.-Ph.D. program of the Imagine Institute (with the support of the Fondation Bettencourt-Schueller). We thank the Association “Turner et vous” for their help and support. Sample processing at IrsiCaixa was possible thanks to the crowdfunding initiative YoMeCorono. D.C.V. is supported by the Fonds de la recherche en santé du Québec clinician-scientist scholar program. K.K. was supported by the Estonian Research Council grant PUT1367. We thank the GEN-COVID Multicenter Study (https://sites.google.com/dbm.unisi.it/gen-covid). We thank the NIAID Office of Cyber Infrastructure and Computational Biology, Bioinformatics and Computational Biosciences Branch (contract no. HHSN316201300006W/HHSN27200002 to MSC, Inc.), the Operations Engineering Branch for developing the HGRepo system to enable streamlined access to the data, and the NCI Advanced Biomedical Computational Science (ABCS) for data transformation support. Biomedical Advanced Research and Development Authority was supported under contract no. HHSO10201600031C (to J.H.). Financial support was provided by the National Institute of Allergy and Infectious Diseases (NIAID) K08AI135091; the Burroughs Wellcome Fund CAMS; the Clinical Immunology Society; and the American Academy of Allergy, Asthma, and Immunology
