101,972 research outputs found
The emerging role of the Sociale Enterprise in an evolving context of trust, partnership and co-production with public organizations
No full textIn a context characterized by economic and social instability, a new generation of public policies aims at finding innovative solutions to manage public organizations through the promotion of trust and accountability. A new paradigm emerged to transform public administrations into more innovative and modern organizations with the aim of improving their functional and financial results. The crisis of the welfare state contributed to increase the capability to establish relationships not only within the public sector, but also through collaboration with organizations from other sectors, promoting a concept of co-production. Present research focuses the attention on the experience of “social enterprise,” defined as an operator in the social economy, whose main goal is to have a social impact rather than to make a profit for its owners or shareholders
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Replication Data for: Individualized text messages about public services fail to sway voters: Evidence from a field experiment on Ugandan elections
No full textThis archive contains the scripts and data needed to reproduce all of the tables and figures in the following article: Jablonski, Ryan S. ⓡ Buntaine, Mark T. ⓡ Nielson, Daniel L. ⓡ Pickering, Paula M. 2021. Individualized text messages about public services fail to sway voters: Evidence from a field experiment on Ugandan elections. Journal of Experimental Political Science
Replication Data for: Individualized text messages about public services fail to sway voters: Evidence from a field experiment on Ugandan elections
No full textThis archive contains the scripts and data needed to reproduce all of the tables and figures in the following article:
Jablonski, Ryan S. ⓡ Buntaine, Mark T. ⓡ Nielson, Daniel L. ⓡ Pickering, Paula M. 2021. Individualized text messages about public services fail to sway voters: Evidence from a field experiment on Ugandan elections. Journal of Experimental Political Science
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
In vitro-in situ comparison study - Data set
No full textThis data set presents the data which were analysed for the following publication:
A comparison between in vitro and randomized in situ models for remineralization of artificial enamel lesions
Jablonski-Momeni A, Lentz J, Jablonski B, Kiesow A, Morawietz M. Sci Rep. 2024 Oct 25;14(1):25295.
doi: 10.1038/s41598-024-76387-w.
Abstract:
The randomized study aimed to evaluate the comparability of in situ (iS) and in vitro (iV) study protocols regarding remineralization of artificial enamel lesions. Two toothpastes (group A: 1450 ppm sodium fluoride, group B: placebo 0 ppm F-), were investigated. IV, a pH-cycling model with toothpaste slurry treatment was applied for 10d. IS, remineralization was performed in 9 participants wearing splints with embedded enamel samples for 10 and 21d, randomly allocated to groups A and B. Samples were scanned by X-ray micro-computed tomography (μCT) and grayscale value line profiles corresponding to mineral density (rel.ΔZ) were analyzed.
T-Test for dependent and independent data and analysis of variance (ANOVA) were used for further analyses (α = 0.05).
Rel.ΔZ of fluoride treated samples (A) were iV = 40.2%, iS 10d = 11.5% and iS 21d = 46.1% (p > 0.05). Rel.ΔZ of placebo treated samples (B) were: iV = − 6.2%, iS 10d = 25.2% and iS 21d = 11.0% (p > 0.05). Remineralization potential of both toothpastes was significantly different regarding iV (p < 0.001) and iS after 21d (p = 0.034), while in case of iS 10d no significant difference was detected (p = 0.4). Despite different study protocols the μCT results after remineralization were comparable between iV and iS.
The results suggest that selected studies can be carried out in faster, simplified iV studies using pH-cycling instead of iS studies
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
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