16 research outputs found
PENGEMBANGAN PERANGKAT BAHAN AJAR TEMATIK TEMA 8 SUBTEMA 1 MANUSIA DAN LINGKUNGAN BERBASIS KEARIFAN LOKAL SISWA KELAS V SEKOLAH DASAR
No full textPenelitian ini bertujuan mengembangkan perangkat bahan ajar tematik tema 8 subtema 1 manusia dan lingkungan berbasis kearifan lokal siswa kelas V sekolah dasar, melalui pendekatan saintifik. Penelitian ini merupakan Research and Development (R&D) dengan model teori Dick & Carey. Teknik analisis yang digunakan pada penelitian ini merupakan analisis deskriptif. Subyek penelitian pada siswa kelas V SDN 002 Karangan, analisis data dengan mengkonversi skor skala rating. Penelitian ini menghasilkan perangkat bahan ajar tematik berbasis kearifan lokal yang layak. Melalui penilaian aspek isi, aspek bahasa, aspek penyajian, strategi pembelajaran, dan aspek tampilan. Persentase penilaian oleh ke tiga ahli yaitu ahli pembelajaran 89%, ahli media 81,07%, dan ahli materi 84,78%, dengan rerata perolehan 84,59%. Produk memenuhi kriteria kepraktisan berdasarkan keterlaksanaan perangkat bahan ajar dengan perolehan nilai 85,4% serta responden guru dan siswa yang termasuk dalam kategori sangat baik. Produk memenuhi kriteria keefektifan berdasarkan hasil belajar siswa pada uji kelas riil dengan nilai ketuntasan 88%. Pengembangan perangkat bahan ajar tematik berbasis kearifan lokal ini mengacu pada silabus dan rencana pelaksanaan pembelajaran yang dikembangkan disesuaikan dengan kegiatan pembelajaran
Author Correction: A Microfluidic Platform to design Multimodal PEG - crosslinked Hyaluronic Acid Nanoparticles (PEG-cHANPs) for diagnostic applications (Scientific Reports, (2020), 10, 1, (6028), 10.1038/s41598-020-63234-x)
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper
SUBJECT AND AUTHOR INDEXS
No full textSUBJECT INDEX IJBE VOLUME 2access credit, 93acquisition, 177AHP, 61, 82, 165arena simulation,43BMC, 69Bojonegoro, 69brand choice, 208brand image, 208brand positioning, 208bullwhip effect, 43burger buns, 1business synergy and financial reports, 177capital structure, 130cluster, 151coal reserves, 130coffee plantation, 93competitiveness, 82consumer behaviour, 33consumer complaint behavior, 101cooking spices, 1crackers, 1cross sectional analytical, 139crosstab, 101CSI, 12direct selling, 122discriminant analysis, 33economic value added, 130, 187employee motivation, 112employee performance, 112employees, 139EOQ, 23farmer decisions, 93farmer group, 52financial performance evaluation, 187financial performance, 52, 177financial ratio, 187financial report, 187fiva food, 23food crops, 151horticulture, 151imports, 151improved capital structure, 177IPA, 12leading sector, 151life insurance, 165LotteMart, 43main product, 61marketing mix, 33, 165matrix SWOT, 69MPE, 61multiple linear regression, 122muslim clothing, 197Ogun, 139Pangasius fillet, 82Pati, 93pearson correlation, 101perceived value, 208performance suppy chain, 23PLS, 208POQ, 23portfolio analyzing, 1product, 101PT SKP, 122pulp and papers, 187purchase decision, 165purchase intention, 33remuneration, 112re-purchasing decisions, 197sales performance, 122sawmill, 52SCOR, 23sekolah peternakan rakyat, 69SEM, 112SERVQUAL, 12Sido Makmur farmer groups, 93SI-PUHH Online, 12small and medium industries (IKM), 61socio-demographic, 139sport drink, 208stress, 139supply chain, 43SWOT, 82the mix marketing, 197Tobin’s Q, 130trade partnership, 52uleg chili sauce, 1 AUTHOR INDEX IJBE VOLUME 2Achsani, Noer Azam, 177Andati, Trias, 52, 177Andihka, Galih, 208Arkeman, Yandra, 43Baga, Lukman M, 69Cahyanugroho, Aldi, 112Daryanto, Arief, 12David, Ajibade, 139Djoni, 122Fahmi, Idqan, 1Fattah, Muhammad Unggul Abdul, 61Hakim, Dedi Budiman, 187Harianto, 93Hartoyo, 101Homisah, 1Hubeis, Musa, 112Hutagaol, M. Parulian, 93Jaya, Stevana Astra, 93Juanda, Bambang, 52Kirbrandoko, 122, 208Manurung, E. Batara, 130Mukhlis Yusuf, Ahmad, 1Najib, Mukhamad, 165, 197Noor Yuliati, Lilik, 208Nugraha, Artadi, 23Nuryartono, Nunung, 151Oktaviani, Rina, 122Prasetyo, Andrie, 101Primadona, Fitry, 165Qaulan Tsaqiela, Bimahri, 43Ramadhan, Arfin, 82Ridho Nurrochmat, Dodik, 33Rifin, Amzul, 23, 151Rusolono, Teddy, 12Sanim, Bunasor, 43Saptono, Imam Teguh, 130Satria, Arief, 61Setiawan, Indarto, 197Simanjuntak, Mangatas, 12Siregar, Hermanto, 130Suharjo, Budi, 197Sukandar, Dadang, 187Sukardi, 23Sumarwan, Ujang, 33, 165Suprayitno, Gendut, 61Suwandi, Ruddy, 82Syahran, Rinaldi, 187Syarief, Rizal, 69Tinaprila, Netti, 101Trilaksani, Wini, 82Ulfah, Iffatul, 33Wahyudi, Imam, 151Widyatami, Sarah, 52Wijayanto, Hari, 112Wiska, Friesgina, 69Zen, Novian, 177</p
An Experimentally Tested Scenario for the Structural Evolution of Eukaryotic Cys(2)His(2) Zinc Fingers from Eubacterial Ros Homologs
No full textThe exact evolutionary origin of the zinc finger (ZF) domain is unknown, as it is still not clear from which organisms it was first derived. However, the unique features of the ZF domains have made it very easy for evolution to tinker with them in a number of different manners, including their combination, variation of their number by unequal crossing-over or tandem duplication and tuning of their affinity for specific DNA sequence motifs through point substitutions. Classical Cys2His2 ZF domains as structurally autonomous motifs arranged in multiple copies are known only in eukaryotes. Nonetheless, a single prokaryotic Cys2His2 ZF domain has been identified in the transcriptional regulator Ros from Agrobacterium tumefaciens and recently characterized. The present work focuses on the evolution of the classical ZF domains with the goal of trying to determine whether eukaryotic ZFs have evolved from the prokaryotic Ros-like proteins. Our results, based on computational and experimental data, indicate that a single insertion of three amino acids in the short loop that separates the β-sheet from the α-helix of the Ros protein is sufficient to induce a structural transition from a Ros like to an eukaryotic-ZF like structure. This observation provides evidence for a structurally plausible and parsimonious scenario of fold evolution, giving a structural basis to the hypothesis of a horizontal gene transfer (HGT) from bacteria to eukaryotes. © 2013 The Author
The "Petakopadesa" with critical apparatus and commentary.
No full textIn editing the Petakopadesa I have made use of the following MSS:- B1. ) B2. ) B3. ) - Palm-leaf MSS in Burmese characters. S. - Paper MS in Sinhalese characters. Unsatisfactory as the MSS are from the point of view of an editor because of the abundance of corrupt readings, B3, however is comparatively more reliable than the others. B2. very closely follows B3, discrepancies being due to the scribe. Bl. and S. on the other hand differ materially from B2. and B3, both in arrangement and in the readings. I have taken the reading that is common to a larger number of the MSS, with a partiality however, for B3. The Petakopadesa is reputed to be the work of MahakaccSyana, the famous disciple of the Buddha. Every chapter of the Petaka end with affirming the authorship of MahakaccSyana. Gandha-Vamsa supports this and tradition in Burma confirms this view. This, however, cannot be accepted as true. Prof. Hardy is of opinion that the author's name was probably Kaooayana which was subsequently changed Into Mahakaooayana. The exact date of the Petaka is as yet undetermined. All that can be said at present is that the work was written sometime between the 5th century A.D. and the date of the later all Pali Canonical works. The Petakopadesa is divided into eight chapters or bhumis. These are the following (1) AriyasacoapakasanS-pathamabhllmi (2) Sasanapatth Snadutiyabhumi. (3) Sattadhitthana -tatlyabhumi. (4) Suttavieaya-oatutthabhuml. (5) HaraTlbhanga-pancamabhllml. (6) Suttatthasamuccayabhumi (7) Harasampatabhumi. (8) Suttarebhangiya. Of these eight bhumis Nos. (2) (5) and (7) hare got their corresponding counterpart in the Netti which is also the work of the same author. The same line of thought, the same outlook of the author can be observed in both the Netti and the Petaka
Complementary therapeutic effects of dual delivery of insulin-like growth factor-1 and vascular endothelial growth factor by gelatin microspheres in experimental heart failure.
No full textAims Strategies to prevent adverse left ventricular (LV) remodelling after myocardial infarction have included several traditional approaches and novel cell-based or gene therapies. Delivery of growth factors in post-infarction heart failure has emerged as a valuable alternative strategy. Our aim was to investigate the effects of sequential release of vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) from biodegradable gelatin microspheres in experimental heart failure. Methods and resultsGelatin hydrogel microspheres were known to guarantee a sustained release of encapsulated growth factors, characterized by an initial burst followed by a slower release. Rats with moderate myocardial infarction were randomized to receive empty microspheres (MI), microspheres loaded with IGF-1 or VEGF, or a combination thereof (DUAL). Myocardial injections of microspheres were performed at the time of surgery, and treatment lasted 4 weeks. Echocardiography, LV catheterization, morphometric histology and immunohistochemistry, and molecular assessment of downstream mediators [e.g. Akt, endothelial nitric oxide synthase (eNOS), and sarco/endoplasmic reticulum calcium ATPase-2 (SERCA-2)] were assessed at the end of the treatment period. Infarct sizes were 33 ± 2, 28 ± 4, 24 ± 3, and 16 ± 3 in the MI, IGF-1, VEGF, and DUAL groups, respectively. IGF-1 attenuated LV remodelling, improved LV systolic and diastolic function, increased myocyte size, and reduced apoptotic deaths, capillary loss, and indexes of inflammation. VEGF-treated animals displayed a marked myocardial neoangiogenesis that led to the formation of mature vessels if combined with IGF-1 delivery. Downstream effects of IGF-1 were principally mediated by the AktmTOR (mammalian target of rapamycin)-dependent pathway, and both growth factors, particularly VEGF, induced a robust and sustained increase of eNOS. ConclusionIGF-1 and VEGF exerted complementary therapeutic effects in post-infarction heart failure. Biodegradable gelatin microspheres provide sustained and controlled growth factor release locally, exposing myocardial tissue without the side effects of systemic administration. © 2011 The Author
Sul filo della memoria. Oralità, storia e storiografia nel racconto di Vittore Bocchetta
No full textLa rappresentazione del sé e della propria storia da parte di testimoni sopravissuti agli orrori della grande storia, comporta un esito in cui i confini tra Storia e storia, memoria soggettiva e documenti d'archivio, fatti accaduti realmente e percezione individuale di essi sono sempre labili, tutt'altro che netti e precisi. Attraverso il racconto, orale e scritto, di Vittore Bocchetta (n. 1918) -fatto di Storia, storia, memoria e mito- e la sua riscrittura intentata da Giuliana Adamo nel volume Una vita contro (2012), si è cercata la legittimazione della veridicità del dictum individuale attraverso il suo riscontro con la controstoria offerta da documenti d'archivio. La voce soggettiva del testimone viene così a fare parte di una polifonia nei cui confronti lo storico dovrebbe porsi in termini di comprensione.The representation of the self and one's own story by witnesses who survived the horrors of history leads to an outcome in which the borders between history and story, subjective memory and archival documents, real events and individual perception of them, are always highly blurred and far from clear and well defined. Through Vittore Bocchetta's (b. 1918) own oral and written account of his life -in which history and story, memory and myth are intertwined- and its rewriting by Giuliana Adamo in her volume Una vita contro (2012), the author has tried to legitimise the individual account with an accurate verification against the counter history offered by archival documents. Thus the witness subjective voice becomes part of a polyphony which historians must try to comprehend
Confini netti e sfumati tra il sé e l’‘altro’: La prospettiva ‘altra’ della scrittrice rom Ceija Stojka
No full textCeija Stojka, a Roma author who was born and lived in Austria and survived the porrajmos, began publishing her writings some decades after her experience of the concentration camps to express the horrors she experienced first-hand. In her autobiographical writings, Stojka does not only talk about her two years as an inmate in Auschwitz, Ravensbrück and Bergen-Belsen, but also about her life before and after the war. While there is a strong need to write in order to bear witness to the experience and to process her trauma, her texts are also a journey into Roma history and into the most hidden spaces of her identity, that of her family and her people. His reflections often dwell on the contact with the majority society and the society’s perception of the Roma. The confrontation with the so-called gagé (non-Roma) helps to add extra pieces of identity and to highlight not only the differences, but also – beyond all stereotypes and categorizations – the similarities between human beings.Ceija Stojka, autrice rom nata e vissuta in Austria e sopravvissuta al porrajmos, inizia a pubblicare i suoi scritti decenni dopo l’esperienza dei campi di concentramento per dare voce agli orrori visti e vissuti in prima persona. Nei suoi scritti autobiografici Stojka non parla solamente dei due anni come detenuta ad Auschwitz, Ravensbrück e Bergen-Belsen, bensì racconta anche della sua vita prima e dopo la guerra. Su questi ultimi aspetti vuole concentrarsi in particolare la presente analisi. Se da una parte è forte il bisogno di scrivere per testimoniare il vissuto e per rielaborare il trauma della sua esperienza, dall’altra i suoi testi sono un viaggio nella storia rom e negli spazi più nascosti della sua identità, di quella della sua famiglia e del suo popolo. Le sue riflessioni si soffermano spesso sul contatto con la società maggioritaria e sulla percezione che la società ha dell’‘altro’ rom. Il contatto e confronto con i cosiddetti gagé (non-rom) aiuta ad aggiungere sempre un pezzo in più di identità e a mettere in risalto non solo le differenze, ma anche – al di là di ogni stereotipo e categorizzazione – le somiglianze tra esseri umani
Education management in the new normal era: a literature study
No full textThe objective of this article is to offer a general overview of how face-to-face learning can be utilized in the context of the new normal era and to identify potential learning models that teachers can employ in addressing educational challenges within this era. In the process of developing this article, a literature review method was employed. The data collection process included a comprehensive review of various references from national and international journals that are pertinent to the subject matter under discussion. Upon conducting thorough research, the author will then select, analyze, and present results in a systematic manner. The learning model represents a significant element within the context of learning. As an individual occupying a pivotal role in the learning process, the teacher is responsible for applying an optimal learning model to ensure the successful attainment of learning objectives. A selection of models that can be utilized for learning within the new normal era includes: Three learning models are worthy of mention: Blended Learning, Flipped Classroom, and Hybrid Learning. In applying any of the aforementioned models to the learning process, it is important to consider the specific characteristics of each learner and the abilities of the instructor
Fabbisogni energetici per edifici caratterizzanti il terziario in Italia: aspetti termici ed illuminotecnici
No full textIl presente lavoro verte sull'individuazione di benchmark di fabbisogno energetico per edifici di riferimento con destinazione d'uso non-residenziale. In particolare, si intende fornire profili tipo di domanda energetica per l'illuminazione artificiale, al fine di valutarne l'effetto sui profili di fabbisogno di energia per la climatizzazione estiva ed invernale, nonché di individuare le variabili che maggiormente incidono sulla loro determinazione. Per giungere a questi risultati, ci si avvale dell'uso di programmi informatici di simulazione dinamica riconosciuti ed impiegati a livello scientifico, in ambito europeo ed extraeuropeo (Energy Plus). La ricerca viene condotta sotto vari aspetti: architettonico, energetico e ambientale. Il primo obiettivo, partendo dalle indicazioni bibliografiche, legislative e normative, è quello di caratterizzare in modo univoco gli edifici di riferimento per le varie destinazioni d'uso oggetto di analisi: edifici per l'istruzione, ed edifici terziari. Gli edifici di riferimento intendono costituire archetipi rappresentativi del patrimonio edilizio italiano. Il secondo obiettivo è di tipo energetico: si intende definire profili tipo di domanda energetica per l'illuminazione artificiale degli ambienti. Si intendono inoltre valutare contestualmente i fabbisogni energetici netti per il riscaldamento e il raffrescamento degli ambienti. L'obiettivo finale è riuscire a determinare le migliori soluzioni progettuali per la minimizzazione del fabbisogno di energia connesso all'illuminazione, in relazione alle destinazioni d'uso dei differenti edifici, nonché le variabili che più incidono per indirizzare al meglio le attenzioni progettuali in caso di nuova realizzazione. Il presente lavoro, dopo un primo inquadramento generale in cui si delinea quello che è lo stato dell'arte della valutazione dei fabbisogni energetici e della ricerca scientifica in materia di illuminazione artificiale di ambienti non residenziali, passa poi ad indagare il significato di archetipo e a definire degli archetipi edilizi per il patrimonio immobiliare costruito a destinazione d'uso scolastica e terziaria. Successivamente vengono descritti i modelli di calcolo impiegati e sono dettagliati i dati di input impiegati per la loro definizione. Sono infine esplicati i risultati ottenuti, con individuazione dei valori di benchmark energetico per gli archetipi edilizi scolastici e terziari, e con l'analisi di quelle che sono le grandezze maggiormente influenti sul fabbisogno energetico per illuminazion
