738 research outputs found
An Enterprise Resource Planning Cloud computing Acceptance Study in German Speaking Europe in a Global Context
No full textAuthor Peter M. Zechner, BScAbstract in englischer SpracheMasterarbeit Universität Linz 201
An Enterprise Resource Planning Cloud computing Acceptance Study in German Speaking Europe in a Global Context
No full textAuthor Peter M. Zechner, BScAbstract in englischer SpracheMasterarbeit Universität Linz 201
Cross-Topic Author Identification -- a Case Study on Swedish Literature
No full textUsing material from the Swedish Literature Bank, we investigate whether common methods of author identification using word frequencies and part of speech frequencies are sensitive to differences in topic. The results show that this is the case, thereby casting doubt on much previous work in author identification. This sets the stage for a broader future study, comparing other methods and generalising the results
Where is the Market? Evidence from Cross-Listings in the U.S.
No full textWe analyze the location of stock trading for firms with a U.S. cross-listing. The fraction of trading that occurs in the United States tends to be larger for companies from countries that are geographically close to the United States and feature low financial development and poor insider trading protection. For companies based in developed countries, trading volume in the United States is larger if the company is small, volatile and technology oriented, while this does not apply to emerging country firms. The domestic turnover rate increases in the cross-listing year and remains higher for firms based in developed markets, but not for emerging market firms. Domestic trading volume actually declines for companies from countries with poor enforcement of insider trading regulation
Re-situer la précarité en temps de crise: Interdépendance et déplacements en espace(s) urbain(s)
No full textThe text, specially translated for this issue of Emulations, inscribes precariousness at the heart of a reflection on the failure of the presumed autonomy of the neoliberal subject. Through the experience of the economic crisis in Spain after 2008, the author describes how the ideology of the middle classes, rooted on a mirage of freedom, on a fictitious autonomy from social structures, has been shaken up. She advocates the development of ties both of interdependence and of codependence, ways of living which are well-known to subordinate populations. And she shows that the violent movement of downward social mobility entailed by the 2008 crisis may have had the advantage of weakening a myth that sees independence as the norm and dependence as the exception. The author thus defends an understanding of precariousness in terms of social reproduction rather than exclusively at the level of production relations to which some approaches have been limiting it.
Ce texte, traduit pour ce dossier, inscrit la précarité au cœur d’une réflexion sur la faillite de l’autonomie présumée du sujet néolibéral. À travers l’expérience de la crise économique de l’Espagne après 2008, l’auteure décrit l’ébranlement de l’idéologie des classes moyennes, fondées sur un mirage de liberté, sur une autonomie fictive vis-à-vis des structures sociales. Elle défend le développement d’interdépendances et de codépendances, modes de vie bien connus des populations subalternes, et montre que le déclassement violent produit par la crise de 2008 aura peut-être eu l’intérêt d’affaiblir un mythe qui voit l’indépendance comme la norme et la dépendance comme l’exception. L’auteure défend ainsi une compréhension de la précarité en termes de reproduction sociale plutôt que de proposition dans les seuls rapports de production à laquelle l’ont en partie cantonnée certaines approches. 
Weiden am Bach
No full text[Musikhandschrift] : nach einem Aquarell von Werner Uhl ; [für Sopran und Klavier] / Franz Koringer. [Text von] Heinz J. Zechner. - Partitur, Autograph - [s.d.]. - 4 Bl. ; 30 x 21 cm - (Nachlass Franz Koringer)
Dynamische Anweisungen mit Bleistift, Korrekturen mit Korrekturflüssigkeit. - Beilage: Textvorlage, Kopieranweisung[Musikhandschrift] : nach einem Aquarell von Werner Uhl ; [für Sopran und Klavier] / Franz Koringer. [Text von] Heinz J. Zechner. - Partitur, Autograph - [s.d.]. - 4 Bl. ; 30 x 21 cm - (Nachlass Franz Koringer)
Dynamische Anweisungen mit Bleistift, Korrekturen mit Korrekturflüssigkeit. - Beilage: Textvorlage, Kopieranweisun
Capital structure: optimal leverage and maturity choice in a dynamic model
No full textWe introduce a dynamic model of optimal capital structure. Analytic solutions for the value of debt and equity are provided when the firm has the opportunity to issue new debt optimally at maturity of current debt. By assuming that this debt consists in a regular coupon bond, and by acknowledging that non positive profits bring the loss of tax deductions, but do not necessarily lead to corporate default, we solve some of the limitations in Kane, Marcus and McDonald (1985) zero coupon bond model, and in Fischer, Heinkel and Zechner (1989) perpetual debt model. A numerical algorithm is proposed to solve the optimization problem. Simulation results indicate that the model is able to replicate standard leverage ratios, debt maturities and credit spreads for reasonable parameter values
Simulation of rock salt dissolution and its impact on land subsidence
No full textExtensive land subsidence can occur due to subsurface dissolution of
evaporites such as halite and gypsum. This paper explores techniques to
simulate the salt dissolution forming an intrastratal karst, which is
embedded in a sequence of carbonates, marls, anhydrite and gypsum. A
numerical model is developed to simulate laminar flow in a subhorizontal
void, which corresponds to an opening intrastratal karst. The numerical
model is based on the laminar steady-state Stokes flow equation, and the
advection dispersion transport equation coupled with the dissolution
equation. The flow equation is solved using the nonconforming
Crouzeix–Raviart (CR) finite element approximation for the Stokes equation.
For the transport equation, a combination between discontinuous Galerkin
method and multipoint flux approximation method is proposed. The numerical
effect of the dissolution is considered by using a dynamic mesh variation
that increases the size of the mesh based on the amount of dissolved salt.
The numerical method is applied to a 2-D geological cross section
representing a Horst and Graben structure in the Tabular Jura of northwestern
Switzerland. The model simulates salt dissolution within the geological
section and predicts the amount of vertical dissolution as an indicator of
potential subsidence that could occur. Simulation results showed that the
highest dissolution amount is observed near the normal fault zones, and,
therefore, the highest subsidence rates are expected above normal fault
zones
Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration
No full textWe previously reported that inactivation of the transmembrane taurine transporter (TauT or solute carrier 6a6) causes early retinal degeneration in mice. Compatible with taurine’s indispensability for cell volume homeostasis, protein stabilization, cytoprotection, antioxidation, and immuno- and neuromodulation, mice develop multisystemic dysfunctions (hearing loss; liver fibrosis; and behavioral, heart, and skeletal muscle abnormalities) later on. Here, by genetic, cell biologic, in vivo1H–magnetic resonance spectroscopy and molecular dynamics simulation studies, we conducted in-depth characterization of a novel disorder: human TAUT deficiency. Loss of TAUT function due to a homozygous missense mutation caused panretinal degeneration in 2 brothers. TAUTp.A78E still localized in the plasma membrane but is predicted to impact structural stabilization. 3H-taurine uptake by peripheral blood mononuclear cells was reduced by 95%, and taurine levels were severely reduced in plasma, skeletal muscle, and brain. Extraocular dysfunctions were not yet detected, but significantly increased urinary excretion of 8-oxo-7,8-dihydroguanosine indicated generally enhanced (yet clinically unapparent) oxidative stress and RNA oxidation, warranting continuous broad surveillance.—Preising, M. N., Görg, B., Friedburg, C., Qvartskhava, N., Budde, B. S., Bonus, M., Toliat, M. R., Pfleger, C., Altmüller, J., Herebian, D., Beyer, M., Zöllner, H. J., Wittsack, H.-J., Schaper, J., Klee, D., Zechner, U., Nürnberg, P., Schipper, J., Schnitzler, A., Gohlke, H., Lorenz, B., Häussinger, D., Bolz, H. J. Biallelic mutation of human SLC6A6 encoding the taurine transporter TAUT is linked to early retinal degeneration
Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems
No full textRelaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo-protein complex which is subsequently recruited for transport by a plasmid-encoded type IV secretion system. In previous work we identified the targeting translocation signals presented by the conjugative relaxase TraI of plasmid R1. Here we report the structure of TraI translocation signal TSA. In contrast to known translocation signals we show that TSA is an independent folding unit and thus forms a bona fide structural domain. This domain can be further divided into three sub-domains with striking structural homology with helicase sub-domains of the SF1B family. We also show that TSA is part of a larger vestigial helicase domain which has lost its helicase activity but not its single-stranded DNA binding capability. Finally, we further delineate the binding site responsible for translocation activity of TSA by targeting single residues for mutations. Overall, this study provides the first evidence that translocation signals can be part of larger structural scaffolds, overlapping with translocation-independent activities
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