117,885 research outputs found
Moderniser la poésie : Huidobro et l’intertextualité en 1917-1918
No full textAux côtés de Vallejo et Neruda, le Chilien Vicente Huidobro est reconnu comme l’un des grands poètes avant-gardistes latino-américains du xxe siècle. L’émergence de la modernité huidobrienne est cependant loin d’être résolue dans toute sa complexité. L’importance octroyée à la théorie créationniste par l’auteur a occulté en partie les véritables enjeux de la question : en effet, il s’agissait, pour Huidobro, de créer ex nihilo, de « faire un poème comme la nature fait un arbre ». Toutefois, l..
García-Huidobro, J., ¿Para qué sirve la política? [Reseña]
No full textReseña de la obra de García-Huidobro, Joaquín, ¿Para qué sirve la política?, Instituto Res Publica, Santiago, 2012, 165 pp
Discovery of Salermide-Related Sirtuin Inhibitors: Binding Mode Studies and Antiproliferative Effects in Cancer Cells Including Cancer Stem Cells
No full textRotili, D., Tarantino, D., Nebbioso, A., Paolini, C., Huidobro, C., Lara, E., Mellini, P., Lenoci, A., Pezzi, R., Botta, G., Lahtela-Kakkonen, M., Poso, A., Steinkühler, C., Gallinari, P., De Maria, R., Fraga, M., Esteller, M., Altucci, L., Mai, A
Splitting the Fucík Spectrum and the Number of Solutions to a Quasilinear ODE
No full textFor
φ
an increasing homeomorphism from
R
onto
R
, and
f
∈
C
(
R
)
,
we consider the problem
(
φ
(
u
′
))
′
+
f
(
u
) = 0
, t
∈
(0
,L
)
, u
(0) = 0 =
u
(
L
)
.
The aim is to study multiplicity of solutions by means of some
gen-
eralized Pseudo Fuˇc ́ık spectrum (at infinity, or at zero). N
ew insights
that lead to a very precise counting of solutions are obtaine
d by split-
ting these spectra into two parts, called Positive Pseudo Fu
ˇc ́ık Spectrum
(PPFS) and Negative Pseudo Fuˇc ́ık Spectrum (NPFS) (at infin
ity, or
at zero, respectively), in this form we can discuss separate
ly the two
cases
u
′
(0)
>
0
and
u
′
(0)
<
0
Development and validation of a HPLC method for the determination of sertraline and three non-chiral related impurities
No full textIn this study, a screening on reversed-phase stationary phases (including C(8), C(18), CN, PEG and amide) was carried out in order to obtain an efficient HPLC method for the determination of sertraline and three of its more closely related synthetical and non-chiral impurities, without using ion-pair reagents. The best results in terms of both retention time and resolution of the target analytes were obtained with a Zorbax Bonus-RP column, which contains a polar amide group embedded in a C(14) alkyl chain. Once the most suitable stationary phase was chosen, the HPLC method was optimized by using a factorial design, evaluating three quantitative factors (column temperature, buffer pH and buffer concentration) in order to find the best conditions which maximize the resolution between impurities A and B (positional isomers) and minimize the total run time. The final HPLC conditions were set by means of a second experimental design, which allowed optimizing the effects of the buffer pH and the proportion of methanol in the mobile phase. The optimal conditions for simultaneously determining sertraline and its impurities, being baseline separated in less than 10min, were finally obtained with Zorbax Bonus-RP column (150mmx4.6mm, 5 um), under isocratic conditions with phosphate buffer (pH 2.8; 10mM)-methanol (63:37, v/v) at 50 degrees C, at the flow-rate of 1.0mL/min. UV detection was set at 220nm. This method was successfully validated following ICH guidelines and it proved to be reliable for the determination of sertraline and related impurities in tablets as pharmaceutical forms
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Letter from unknown writer to Jesse L. Boyce
No full textLetter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
