16 research outputs found
Effectiveness of banana leaves extract (Musa paradisiaca L.) for wound healing
No full textBanana leaves (Musa Paradisiaca, L.) has not been widely used in the treatment purpose of this study was to examine the wound healing activity of the gel of banana leaves (Musa paradiasiaca L.) and determine the most effective concentration for wound healing.Target research is to provide natural wound treatment alternatives. The method used is eksperimental.Prosedur research study began with the identification of a banana leaf, banana leaf extraction, formulation of banana leaf extract gel with a concentration of 1%, 5%, 10% and testing to the test animals were harmed .Animal test are grouped into 5 groups the negative control group (base gel), a positive control (bioplacenton), and 3 groups treatment. Measuring of diameter wound on day-1 through day 7. The observation was tested by using ANOVA and Post Hoc Tukey HSD. ANOVA test results showed a significant difference between the mean percentage of wound healing all groups Treatment .The result of Post hoc Tukey HSD at the 95% confidence level showed significant differences in the negative control group when compared to the positive control group and the treatment group gel 5% and 10% .It indicates that the positive control, gel 5% and 10% have a wound healing effect. Positive control group compared with the group treated gel 5% and 10% showed significant differences that the average value of the percentage of wound healing is higher than the positive control treatment group. It means the difference meant that the positive control has better activity. While the group gel 5% when compared with the 10% gel group no significant difference in this case means the group gel 5% with 10% having a comparable effectiveness of wound healing
STUDI PEMBERIAN INFORMASI TENTANG TEKNIK PENGGUNAAN METERED DOSE INHALER OLEH APOTEKER DAN TENAGA TEKNIS KEFARMASIAN DI APOTEK KECAMATAN MERTOYUDAN, KABUPATEN MAGELANG
No full textAsma merupakan masalah kesehatan yang serius dan dapat menyerang semua kelompok usia. Pemberian obat secara inhalasi merupakan rute yang paling penting dalam pengelolaan asma.Tujuan penelitian ini adalah untuk mengetahui gambaran pemberian informasi tentang teknik penggunaan Metered Dose inhaler oleh apoteker dan tenaga teknis kefarmasian di apotek Kecamatan Mertoyudan, Kabupaten Magelang. Penelitian ini merupakan penelitian deskriptif dengan menggunakan pendekatan investigation research yaitu mengumpulkan informasi terkait pemberian informasi teknik penggunaan Metered Dose Inhaler oleh apoteker dan tenaga teknis kefarmasian dengan cara investigasi. Data yang diperoleh kemudian dianalisis dan dibuat kesimpulan . Variabel dalam penelitian ini adalah pemberian informasi tentang penggunaan Metered Dose Inhaler oleh apoteker dan tenaga teknis kefarmasian. Pengambilan data dilakukan pada bulan Februari 2018. Populasi dalam penelitian ini adalah semua Apoteker dan Tenaga Teknis Kefarmasian di Wilayah Kecamatan Mertoyudan, Kabupaten Magelang. Sampel dalam penelitian ini adalah Apoteker dan Tenaga Teknis Kefarmasian yang praktek di apotek Wilayah Kecamatan Mertoyudan, Kabupaten Magelang. Observasi yang dilakukan oleh peneliti di Kecamatan Mertoyudan dengan total 15 apotek, didapatkan 40% apotek tersedia obat inhaler dan 60% apotek tidak tersedia karena jarang pasien yang membeli dan harga obat yang mahal. Hasil penelitian menunjukkan bahwa dari 9 tahapan penggunaan Metered Dose inhaler, semua responden mendemonstrasikan tahapan buka tutup inhaler dan tekan canister dan hanya 6,67% yang memberikan informasi hembuskan napas secara perlahan sampai tidak ada sisa udara yang dapat dihembuskan. Kesimpulan apoteker yang memberikan informasi lengkap tentang teknik penggunaan inhaler adalah sebanyak 6,67%
EVALUASI TERAPI ORAL TERHADAP HASIL TERAPI PASIEN ASMA DI BALAI KESEHATAN PARU MASYARAKAT (BKPM) WILAYAH MAGELANG
No full textBackground: Asthma is a chronic disease that is easily found and is clinically
characterized by recurrent episodes of coughing, shortness of breath, chest tightness
and wheezing (wheezing). Asthma therapy in adult patients administered orally,
inhalation and parenteral. Prescribing of asthma patients in the outpatient Community
Lung Health Center (BKPM) Magelang region mostly using orally administered
drugs due to the high price of inhalers. This study aims to determine the effect of oral
therapy on treatment outcome and identify side effects that arise due to the use of oral
therapy in patients with asthma
Methods: This study is an observational study with prospective data collection from
February to April 2014. Data taken from the results of Peak Flow Meter, medical
records and data collection sheets. Patients who met the inclusion criteria in 75
patients but only 71 patients were followed throughout the study process. To prove
the effect before and after the use of oral therapy to therapeutic outcomes used paired
t test and Wilcoxon test. Used to compare changes in independent t test and Chisquare
test and Fisher alternatives.
Result: The results showed an increase in the value of the APE of 92.68 ± 66.70 after
1 month of oral therapy (P = 0.000). The frequency of attacks at the beginning of the
study most of the patients � 4x/week many as 33 patients (46.48%), after 1 month of
oral therapy frequency of attacks most patients become 1-2x/month as many as 48
patients (67.61%). Of the 71 patients who received oral therapy in 19 patients
(26.76%) encountered side effects palpitations, gastritis and increased appetite.
Conclusion: The use of oral therapy showed progress by increasing the value of the
results of therapy and decrease in frequency of attacks APE side asma. Side effects
observed in 19 patients (26.76 %) of 71 patients.
Keywords : asthma, oral therapy, therapeutic outcomes, side effect
Evaluation of The Implementation of Sharia-Based Pharmaceutical Service Standards (A Qualitative Case Study)
No full textBackground: National health laws and best practices from other countries have helped Indonesia set standards for pharmaceutical services. However, there is still limited research on the application of Sharia principles in pharmacy services, particularly within community pharmacies. These standards are based on ideas from the Quran, Hadith, and fatwas from well-known Islamic scholars. They put these ideas into action by making sure that medicines don't contain any illegal substances, being sensitive to gender issues, and providing services that respect patients' dignity, as Islamic teachings say they should.
Aims: This study aims to evaluate the implementation of Sharia-based pharmaceutical service standards through a qualitative case study at the Muhammadiyah Charity Education Pharmacy. This pharmacy's unique role as an integrated platform for pharmacy education, community service, and the application of Islamic values makes it an appropriate context for examining the implementation of Sharia-compliant pharmaceutical services.
Methods: A qualitative case study design was used, involving observations and semi-structured interviews. NVivo 12 software was employed for thematic and cluster analysis. Data were coded inductively by independent researchers and validated through consensus. Pearson correlation coefficients were used to identify the strongest relationships between service quality items. The informants involved were 1 pharmacist and 3 pharmaceuticals technical staff.
Results: Reliability, responsiveness, empathy, tangibles, and assurance are the themes that emerged from this study. The studies found that in the reliability dimension, fulfilling order service and distributor reliability showed the highest correlation (r=0.98), emphasizing the importance of commitment and trust in sharia-based service. In the responsiveness dimension, the most significant relationship (r=1.00) emerged between complaint resolution and clear division of duties, reflecting the role of communication and accountability. For assurance, the highest correlation (r=0.96) indicated the critical role of clear, understandable information in building trust. The empathy dimension revealed that prioritizing humanity and non-discriminatory service (r=0.52) aligned closely with the values of justice and compassion. Lastly, in the tangibles (physical) dimension, the presence of a patient prayer space showed a strong link to perceptions of cleanliness and professionalism (r=0.67), although implementation was still limited.
Conclusion: By combining Islamic ethical principles with service quality metrics, the application of sharia-based service standards in pharmaceutical care improves patient satisfaction. However, some aspects still need improvement, especially the physical facilities and assurance under heavy workload. These findings provide insightful guidance on how to develop appropriate interventions, such as training programs, SOPs, and infrastructure modifications, to ensure pharmaceutical services comply with Sharia law while improving overall service quality for lawmakers, educational institutions, and businesses providing Islamic-based pharmaceutical services
COMMUNITY PHARMACY PROFILE IN TEMANGGUNG REGENCY BASED ON NUMBER OF VISITORS, NUMBER OF PRESCRIPTIONS, SELF-MEDICATION SERVICES AND INCOME
No full textObjective: Pharmacy is a location for carrying out pharmaceutical tasks for pharmacists. Pharmacy also acts as a business entity that requires the application of appropriate management techniques to operate profitably and still comply with the principles of pharmaceutical service standards. The purpose of this study was to determine the profile of community pharmacies based on the number of visitors, the number of prescriptions, self-medication services and income.
Methods: This study uses a quantitative approach with descriptive and correlational research designs. Descriptive aims to describe the profile of the pharmacy, the number of visitors to the pharmacy, the number of prescriptions, the number of self-medication services and the trend of pharmacy income over time. Correlational: aims to identify the relationship between the length of establishment and the ratio of pharmacies to the number of visitors and income; the relationship between the number of pharmacies and the ratio of pharmacies to the number of prescriptions.
Results: Results of 57 pharmacies spread across 20 sub-districts. The largest number of pharmacies is in Temanggung District, namely 13 pharmacies with a percentage of 22.81%. However, there are still 3 sub-districts that do not have a pharmacy. Most pharmacies have an average of 30-50 patients per day and 72.73% provide self-medication services for 10-50 patients. Most pharmacies serve prescriptions<1 sheet per day. As many as 40% of pharmacies have a low income (more than Rp. 464,260 and less than Rp. 1,617,088). The results of the bivariate analysis showed that the length of establishment was related to the average income and the number of pharmacies was related to the number of prescriptions served.
Conclusion: Factors related to the amount of income and the number of prescriptions are the length of establishment of the pharmacy and the number of pharmaceutical service facilities in the form of pharmacies
The Weight Performance Stability of Mice on Modeling Obesity-Associated Hyperglycemia Induced by Dextrose Monohydrate
No full textPreviously, streptozotocin and alloxan were employed to imitate hyperglycemia in mice. High doses of sucrose were also induced as an alternative. Due to body mass index has been associated with hyperglycemia, the evidence of weight body index in various induction alternate kinds, however, have not been fully reported. Here-in, we report on the weight performance stability of mice body weight induced by dextrose, streptozotocin, and alloxan. To begin, all mice were divided into six groups of five, with one reserve in each. Following seven days of acclimatization, the mice were induced for nine days of hyperglycemia modeling; alloxan (Groups A and D), streptozotocin (Group B and E), dextrose monohydrate (Groups C and F). On preclinical research animals modelling related to obesity-associated hyperglycemia in mice, dextrose monohydrate induction was most successful than streptozocotin and alloxan induction, which performed best during the induction period (31% weight growth) and after metformin intervention (36% weight growth). Overall, dextrose monohydrate is most suitable to be used for modeling type 2 diabetes mellitus test animals rather than alloxan and streptozocotin
The implementation of antimicrobial stewardship in Indonesia: a regional survey in hospitals
No full textAntibiotic resistance is becoming more common worldwide because of irrational antimicrobial use. Antimicrobial resistance occurs practically all over the world, leading the World Health Organization (WHO) to create a “Global Action Plan on Antimicrobial Resistance” in 2015. This study investigates the implementation of the antimicrobial stewardship program’s actions in Indonesia’s hospitals from the perspective of health professionals. This survey describes activities, the role of pharmacists, the impacts and barriers to the antimicrobial stewardship program. Purposive sampling was used to recruit respondents, including doctors, pharmacists, nurses, pharmaceutical technical employees, and laboratory analysts from two referral hospitals in Central Java Province, Indonesia. Activities of the antimicrobial stewardship program in hospitals are to develop policies and guidelines for using hospital antibiotics 81.48, develop policies on antimicrobial stewardship 74.07, and disseminate and increase understanding and awareness of antimicrobial stewardship principles 55.56. The role of the pharmacist in the antimicrobial stewardship program was to make policies and guidelines for using antibiotics and work programs to control resistance 81.50, information services for patients and their families and other health workers 74.10, with the therapy committee team to select and procure antibiotics 55.70 and provide patient counseling 51.90. The effect of the antimicrobial stewardship program improved the quality of handling infectious cases, antibiotic use 55.56, and germ patterns 40.74. The obstacles to implementing the antimicrobial management plan are infrastructure 40.74 and finance 37.04. Antimicrobial stewardship programs have been implemented in Indonesian hospitals, but some obstacles remain © 2022 Journal of Advanced Pharmacy Education & Researc
Knowledge and quality of life among Indonesian students during the COVID-19 pandemic
No full textThe increasing of online coronavirus disease-2019 (COVID-19) information-sharing in digital media can contribute to the emergence of misinformation in public. Much insufficient knowledge will confuse public understanding and affect their quality of life. The study purposed to assess the knowledge and its influence on Indonesian students' quality of life during the COVID-19 crisis. A cross-sectional study was conducted between October and December 2020 by distributing online questionnaires. The data analysis was run through the Spearman correlation method by using SPSS version 21.0. A total of 200 respondents aged over 17 years were recruited using a snowball sampling technique. Most study respondents had insufficient knowledge about COVID-19, 23% of them had moderate knowledge, and only 17.5% had high knowledge. They obtained primary sources of COVID-19 information from social media platforms. The results showed that health science students have a better understanding than social science students (ρ<0.001). The level of knowledge has a significant associated with psychological domain (ρ=0.020), environmental domain (ρ=0.046), and overall quality of life (ρ=0.047). Thus, the media control center is vital to encounter valid information in providing better knowledge and quality of life during a pandemic
The Knowledge and Attitude of Universitas Muhammadiyah Magelang Pharmacy Students on National Health Programs–a Descriptive Study
No full textAntidiabetic Activities of Broccoli Extracts (Brassica oleracea L.var italica) on Mice Induced Streptozotocin-Nicotinamide
No full textSeveral plant species have been used for the treatment of diabetes. Research on plants that can be used to treat diabetes such as Cinnamomum cassia and Cinnamomum zeylanicum, Piper sarmentosum Roxb, Nelumbo nucifera, Ceiba petandra Memecylon malabaricum. Broccoli (Brassica oleracea L var italics) is a flower of vegetables like cabbage plants. Broccoli juice is made capable of direct and indirect effects on the reduction of blood LDL; the indirect effect is by repairing pancreatic beta cells and increasing insulin sensitivity. The purpose of this study was to determine whether broccoli has activity as antidiabetic. The subjects consisted of 15 mice induced with nicotinamide 70 mg/kg BW and Stz 150 mg/kg BW. Diabetic mice were divided into the positive control group (glibenclamide), negative control group (CMC Na) and three treatment groups. The test material is broccoli extract dose 75 mg / kg BW, 150 mg /kg BW and 300 mg/kg BW given peroral for 14 days. Anova test results showed that there was a significant difference in the average percentage of decreased blood glucose levels in all treatments. The result of Post Hock Tukey HSD test with a 95% confidence level showed a significant difference in the negative control group compared with positive control group and extract 300mg / kg BW. This shows that positive control group and extracts 300mg / kg body weight have an activity to decrease blood glucose level
