5,526 research outputs found
Evaluation of vegetation and stream health within sites supported by the Hamilton City Council Plants for Gullies Programme
Between August 2012 and March 2013, the Environmental Research Institute, University of Waikato, conducted a survey of randomly selected Hamilton gully sites which had received plants from the Hamilton City Council’s Plants for Gullies Programme. This survey assessed recent plantings, existing gully vegetation and stream health, along with property owner awareness and engagement with the key restoration principles.
The Plants for Gullies Programme has been extremely well received by the Hamilton community and gully owners. Survey participants were actively restoring their gully sites with the most common goal (c. 40%) being the establishment of native plant dominance within 10 years. Gully owners have a good understanding of restoration theory and practise; on average, plant placement in the gullies scored 15.7 out of 20 with consideration of plant environmental requirements and the concept of ecosourcing was understood by c. 76% of landowners surveyed. Also, most of the interviewed participants (c. 80%) were active in seeking guidance from other gullies, often through organised tours.
Current stream health was qualitatively assessed and characterised at each of the gully sites. Results provide baseline data for future monitoring. The majority of surveyed sites (c. 50%) had sand or silt substrate and the Bankwood gully had the best features for fauna habitat (e.g. debris and areas of low flow). At the time of visit, c. 60% of surveyed streams had clear water clarity. The poorest water clarity scores were in the Waitawhiriwhiri gully. When assessed on width, length and density, the average riparian buffer score was 12.8 out of 20 while the average stream shading score was 12.7 out of 20. The average bank stability score was 13.1 out of 20, reflecting an erosion problem that many gully owners talked about.
Surveyed gullies were diverse in terms of native and exotic vegetation structure and composition; native species contributed between c. 30% to 100% of surveyed trees and shrubs, whereas groundcovers were predominantly exotic. This assessment of gully sites has shown that the Plants for Gullies Programme improves native species diversity through the re-introduction of species that are not naturally regenerating. The Plants for Gullies programme is a powerful tool for engaging private landowners and making cost-effective change to Hamilton City’s native biodiversity. There is now a community of willing gully owners who will continue to restore their gullies with the support of a programme or network. It is our recommendation that the Plants for Gullies Programme is reinstated before this community loses momentum
Understory restoration in Hamilton urban forests
Research was undertaken to determine how the understory vegetation of Hamilton urban forests compares with reference old-growth forests in rural locations, identify causes for differences, and develop methods to enhance species diversity. Understory vegetation was measured in five rural old-growth forests and compared with 20 urban forests, categorised into four age groups, to assess differences in richness, composition and density. Environmental profiling quantified soil type, nutrient levels, pH, moisture content, understory light transmittance, temperature and vapour pressure deficit of selected forests to identify variation across the forest categories and determine if environmental conditions were the chief cause for vegetative differences. Three native species (Melicytus micranthus, Hedycarya arborea and Coprosma arborea), absent from or less abundant in urban forests, were reintroduced into forest sites to assess their growth, survival and potential for becoming a prominent component in Hamilton City forests.
Urban forests displayed reduced native understory diversity comprising only 61.5% of the native understory species found in the rural old-growth forests. Native understory species richness and density decreased from the rural old-growth forest category to the youngest urban forest group. Rural old-growth forests averaged 7.96 species and 41.28 stems per 50 m² compared to 2.68 species and 8.20 stems per 50 m² in the youngest urban forests. The exotic understory stem density trend was reverse. Reduced understory diversity in second-growth and urban forests is widely reported overseas but has not been quantified in New Zealand previously.
Soil nutrients and acidity increased from the youngest to the oldest urban forest category. Light transmittance into the understory decreased with forest age from 18.43% in the youngest urban forest group to 4.17% in the rural old-growth forest category during winter and spring. Buffering patterns were evident in rural oldgrowth forests with higher temperatures and vapour pressure deficits outside the forests by as much as 3 ºC and 0.3 kPa respectively during the day, compared to the forest interior. Similar patterns were evident in urban forests during spring but the interior temperatures and vapour pressure deficits were not as low, compared to the rural forests. Environmental profiling proved there were significant differences in environmental conditions between the forest categories and that these were within the range of values reported elsewhere in New Zealand.
Survival and growth rates between 77.8 to 100% and 2.7 to 12.1 cm respectively, for the three translocated species over the measured seven months were on par with other New Zealand trials and suggest the selected species can grow and establish viable populations within urban forests. The reintroduction success further indicates that the reduced diversity of urban forests is likely to result from the effects of fragmentation and isolation and urban pressures.
Active reintroduction of missing or less abundant native understory species is the best method to improve diversity in Hamilton urban forests. The species experimented with should be included in forest enrichment planting plans as early as 5 to 15 years. Management plans should address active removal of exotic species including methods for manipulation of developing vegetation to favour enhancement of native understory diversity in urban forests
Ecological values of Hamilton urban streams (North Island, New Zealand): constraints and opportunities for restoration
Urban streams globally are characterised by degraded habitat conditions and low aquatic biodiversity, but are increasingly becoming the focus of restoration activities. We investigated habitat quality, ecological function, and fish and macroinvertebrate community composition of gully streams in Hamilton City, New Zealand, and compared these with a selection of periurban sites surrounded by rural land. A similar complement of fish species was found at urban and periurban sites, including two threatened species, with only one introduced fish widespread (Gambusia affinis). Stream macroinvertebrate community metrics indicated low ecological condition at most urban and periurban sites, but highlighted the presence of one high value urban site with a fauna dominated by sensitive taxa. Light-trapping around seepages in city gullies revealed the presence of several caddisfly species normally associated with native forest, suggesting that seepage habitats can provide important refugia for some aquatic insects in urban environments. Qualitative measures of stream habitat were not significantly different between urban and periurban sites, but urban streams had significantly lower hydraulic function and higher biogeochemical function than periurban streams. These functional differences are thought to reflect, respectively, (1) the combined effects of channel modification and stormwater hydrology, and (2) the influence of riparian vegetation providing shade and enhancing habitat in streams. Significant relationships between some macroinvertebrate community metrics and riparian vegetation buffering and bank protection suggest that riparian enhancement may have beneficial ecological outcomes in some urban streams. Other actions that may contribute to urban stream restoration goals include an integrated catchment approach to resolving fish passage issues, active reintroduction of wood to streams to enhance cover and habitat heterogeneity, and seeding of depauperate streams with native migratory fish to help initiate natural recolonisation
Are treatment preferences relevant in response to serotonergic antidepressants and cognitive-behavioral therapy in depressed primary care patients? Results from a randomized controlled trial including a patients' choice arm
BACKGROUND: Little is known about the influence of depressed patients' preferences and expectations about treatments upon treatment outcome. We investigated whether better clinical outcome in depressed primary care patients is associated with receiving their preferred treatment. METHODS: Within a randomized placebo-controlled single-centre 10-week trial with 5 arms (sertraline; placebo; cognitive-behavioral group therapy, CBT-G; moderated self-help group control; treatment with sertraline or CBT-G according to patients' choice), outcomes for 145 primary care patients with mild-to-moderate depressive disorders according to DSM-IV criteria were investigated. Preference for medication versus psychotherapy was assessed at screening using a single item. Post-baseline difference scores for the Hamilton Depression Rating Scale (HAMD-17) were used to assess treatment outcome (mixed-model repeated-measures regression analysis). RESULTS: Depressed patients receiving their preferred treatment (n = 63), whether sertraline or CBT-G, responded significantly better than those who did not receive their preferred therapy (n = 54; p = 0.001). The difference in outcome between both groups was 8.0 points on the HAMD-17 for psychotherapy and 2.9 points on the HAMD-17 for treatment with antidepressants. Results were not explained by differences in depression severity or dropout rates. CONCLUSIONS: Patients' relative preference for medication versus psychotherapy should be considered when offering a treatment because receiving the preferred treatment conveys an additional and clinically relevant benefit (HAMD-17: +2.9 points for drugs; +8.0 points for CBT-G) in outcome
Seed rain and soil seed banks limit native regeneration within urban forest restoration plantings in Hamilton City, New Zealand
Restoration of native forest vegetation in urban environments may be limited due to isolation from native seed sources and to the prevalence of exotic plant species. To investigate urban seed availability we recorded the composition of seed rain, soil seed banks and vegetation at native forest restoration plantings up to 36 years old in Hamilton City and compared these with naturally regenerating forest within the city and in a nearby rural native forest remnant. Seed rain, soil seed banks (fern spores inclusive) and understorey vegetation in urban forest were found to have higher exotic species richness and lower native species density and richness than rural forest. Both understorey vegetation and soil seed banks of urban sites >20 years old had lower exotic species richness than younger (10–20 years) sites, indicating a developmental threshold that provided some resistance to exotic species establishment. However, the prevalence of exotic species in urban seed rain will allow reinvasion through edge habitat and following disturbance to canopy vegetation. Persistent soil seed banks from both urban and rural sites were dominated by exotic herbaceous species and native fern species, while few other native forest species were found to persist for >1 year in the seed bank. Enrichment planting will be required for those native species with limited dispersal or short-lived seeds, thus improving native seed availability in urban forests as more planted species mature reproductively. Further research into species seed traits and seedling establishment is needed to refine effective management strategies for successful restoration of urban native forests
Vírus do caos contra a ordem de Direito. Como a covid-19 está abalando a estrutura da vida contemporânea e gerando incertezas para o futuro
Perancangan Sistem Informasi Pengelola Barang/Inventaris Di Jc Komp
Inventory information system is a system used to enter inventory data into the database, so that there are no errors in input, output data, and reporting based on the desired data. based on surveys and interviews with jc comp personnel, information was obtained that the existing system in the jc comp warehouse section is still manual. therefore, the system that will be created by the author is the result of a replication of the existing system in the jc comp warehouse section. in addition to the process of input and output of goods, this information system is also equipped with features for creating data reports, input and output of goods, and searching for goods data by item name. with the inventory information system is expected to be useful for the warehouse parts jc comp. By implementing this system in the jc comp warehouse, it is hoped that it can reduce errors that may occur. this system is also expected to further speed up the process of input, output, and report generation, which in turn will help the jc comp warehouseSistem Informasi Persediaan Barang adalah sebuah sistem yang digunakan untuk memasukkan data-data persediaan barang ke dalam database, sehinggga tidak terjadi kesalahan dalam input, output data, dan pembuatan laporan berdasarkan data yang diinginkan. Berdasarkan survey dan wawancara dengan bagian personalia Jc Komp, didapatkan informasi bahwa sistem yang ada dibagian gudang Jc Komp masih manual. Oleh karena itu, sistem yang akan dibuat oleh penulis adalah hasil replikasi dari sistem yang telah ada dibagian gudang Jc Comp. Selain proses input dan output barang, pada sistem informasi ini juga dilengkapi fitur pembuatan laporan data, input, dan output barang, dan pencarian data barang berdasarkan nama barang. Dengan adanya Sistem Informasi persediaan barang ini diharapkan dapat bermanfaat bagi bagian gudang Jc Komp. Dengan diterapkannya sistem ini pada bagian gudang Jc Comp, maka diharapkan dapat mengurangi kesalahan-kesalahan yang mungkin terjadi. Sistem ini juga diharapkan dapat lebih mempercepat proses input, output, dan pembuatan laporan yang pada akhirnya dapat membantu bagian gudang Jc Komp
JC and BK polyomavirus-like particles as targets of innate and adaptive humoral immunity
JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV) were identified as the first of now more than 12 human polyomaviruses (HPyVs). The average JCPyV and BKPyV seroprevalence rates in adults are 70% and 90%, respectively. After asymptomatic infection both viruses persist in the renourinary tract. In fact, asymptomatic viruria is detectable in one-third of general population. However, in immunocompromised patients, JCPyV and BKPyV replication may progress to significant diseases. Hence, JCPyV can cause progressive multifocal leukoencephalopathy (PML) in patients with HIV-AIDS, malignancies or autoimmune diseases under immunosuppressive treatment. BKPyV can be a cause of polyomavirus-associated nephropathy (PyVAN) in kidney transplant recipients or hemorrhagic cystitis (PyVHC) after allogeneic hematopoietic stem cell transplantation. Due to more frequent application of immunosuppression, the risk of developing these diseases has increased in the last few decades. The risk of PML development is estimated to be 100-fold higher for JCPyV-seropositive patients in comparison to JCPyV-seronegatives. Most cases of PyVAN and PyVHC have been tested positive for BKPyV at the moment of disease diagnosis. Unfortunately, there is no specific antiviral therapy against any of these HPyV diseases. Thus, current strategies to avert PyVAN or PyVHC aim at identifying patients with BKPyV viremia and reducing immunosuppression. Similar strategies for PML have not been effective, since JCPyV viremia is usually not detected prior to or at the diagnosis of disease. The fate of BKPyV and JCPyV virus-like particles (VLPs) was examined in an animal model corresponding to primary viremia in non-immune host. Radioactively labeled VLPs were used to assess blood decay, organ, and hepatocellular distribution of ligand, and non-labeled VLPs to examine cellular uptake by immunohisto- and cytochemistry. Rapid distribution of both BKPyV and JCPyV VLPs to the liver was observed, with lesser uptake in kidney and spleen. Liver uptake was predominantly observed in LSECs. Blood half-life and tissue distribution of both wild-type JCPyV VLPs and two mutant JCPyV VLPs (L55F and S269F), lacking sialic acid binding affinity, were similar, indicating involvement of non-sialic acid receptors in cellular uptake. We concluded that LSECs very effectively cleared a large fraction of blood-borne BKPyV and JCPyV VLPs, indicating a central role of these cells in early removal of polyomavirus from the circulation. Moreover, we observed that a subpopulation of endothelial cells in kidney, the main organ of polyomavirus persistence, showed selective and rapid uptake of VLPs, suggesting a role in viremic organ tropism (Simon-Santamaria et al., p. 54). Giving the increasing clinical need to reliably determine JCPyV and BKPyV IgG levels in patients at risk, we first reviewed and optimized serological tools for JCPyV and BKPyV IgG detection including virus-like particle (VLP)-based ELISA. We demonstrated that although no statistically significant differences in intraassay and interassay variability were revealed for JCPyV serology of 400-fold diluted sera from healthy donors, qualitative differences were seen in the identification of the individual JCPyV serostatus. The cause of discordance for approximately 10% of sera resulted from a low IgG activity close to the cutoff of the assay. Therefore we standardized the ELISA using reference serum for normalization. Moreover, we developed a preadsorption assay with cutoff of 35% reduction of the JCPyV IgG activity after preincubation with JCPyV VLPs. Importantly, we excluded BKPyV antibody cross-reactivity by testing JCPyV IgG positive sera in preadsorption assay using BKPyV VLPs. In conclusion, we showed that VLP-based ELISA with normalization can serve as a reliable tool for JCPyV IgG serology. Additionally, the preadsorption assay can help with unequivocal determination of JCPyV serostatus for samples with low IgG levels. (Kardas et al., p. 72). We also normalized this VLP-based ELISA for BKPyV IgG detection and showed that for seroepidemiology studies, normalized JCPyV and BKPyV IgG ELISA at 1:200 serum dilution provides optimal sensitivity and specificity with the lowest false-positive and false-negative rate. However, for individual risk assessment, 100-, 200-, and 400-fold dilutions combined with preadsorption for low-reactive sera might be the most appropriate (Kardas et al., p. 82). This improved ELISA was used to investigate JCPyV and BKPyV specific antibody levels in several clinical studies: (1) one case of PML patient where positive JCPyV IgG status was compatible with other PML-indicating symptoms (Kurmann et al., p. 90); (2) one case of PyVAN caused by JCPyV rather than BKPyV, as confirmed by JCPyV IgG/IgM positive and BKPyV IgG/IgM negative results (Lautenschlager et al., 99); (3) one case of PyVHC patient after allogeneic hematopoietic stem cell transplantation where increasing BKPyV IgG activities were in line with progression of BKPyV viremia (Koskenvuo et al., p. 106). Further, by serological testing of 122 immunocompetent and 63 immunocompromised patients we demonstrated that the BKPyV IgG level is age-dependent, with the highest values between 20 and 30 years (Schmidt et al., p. 119). In another study we compared serological outcomes of ELISA utilizing two different antigens in terms of prognostic value in prostate cancer development. To accomplish this we utilized improved ELISA for BKPyV IgG activity to both BKPyV VLPs and BKPyV LTag. Testing of 226 patients undergoing radical prostatectomy for primary prostate cancer revealed that BKPyV VP1 serostatus, in contrast to BKPyV LTag, has no prognostic value in prostate cancer progression (Keller et al., p. 125). In conclusion, we provided a new input into knowledge about tropism and clearance of polyomaviruses from blood. Moreover, we established a reliable and sensitive VLP-based assay for specific detection of JCPyV and BKPyV IgG and IgM. Serostatus based on ELISA results was compatible with other symptoms of BKPyV- and JCPyV-related diseases
"Blood pressure and plasma noradrenaline during single high-dose beta-adrenoceptor blockade"
"Blood pressure and plasma noradrenaline during single high-dose beta-adrenoceptor blockade"
- …
