211 research outputs found
First axion dark matter search with toroidal geometry
No full textWe firstly report an axion haloscope search with toroidal geometry. In this pioneering search, we exclude the axion-photon coupling g aγγ down to about 5×10 −8 GeV −1 over the axion mass range from 24.7 to 29.1 μ eV at a 95\% confidence level. The prospects for axion dark matter searches with larger scale toroidal geometry are also considered. © 2017 American Physical Society3411Nsciescopu
Electric and magnetic energy at axion haloscopes
No full textWe review the electro-magnetic energy at axion haloscopes and find that the electric and the corresponding magnetic energy stored in the cavity modes or, equivalently, the mode dependent electric and magnetic form factors are the same regardless of the position of the cavity inside the solenoid. Furthermore, we extend our argument to the cases satisfying ∇ ⃗ ×B ⃗ external =0 , where B ⃗ external is a static magnetic field provided by a magnet at an axion haloscope. Two typical magnets, solenoidal and toroidal, satisfy ∇ ⃗ ×B ⃗ external =0 ; thus, the electric and the corresponding magnetic energy stored in the cavity modes are always the same in both cases. The energy, however, is independent of the position of the cavity in axion haloscopes with a solenoid, and depends on those with a toroidal magnet. © 2016 American Physical Society2211Nsciescopu
Crystallite growth limits in amorphous oxides
No full textPost deposition thermal annealing of amorphous coatings improves optical properties of dielectric mirrors. However, excessive temperatures cause crystallization, resulting in a degradation of mechanical and optical properties. Therefore, annealing is limited to temperatures 'below' the crystallization threshold. The threshold is determined by x-ray diffraction (XRD) measurement which requires a significant amount of crystallized material for detection, yet it has been shown that a population of crystallites may exist in otherwise amorphous coatings below the threshold temperature. In this study XRD measurements show crystallites that grow during annealing within amorphous oxide coatings to a limited and predictable size predicated on the difference in density between the crystal and the surrounding amorphous phase and the average material's Young's modulus. These crystallites may be the point-like, extremely weak scatterers revealed in the LIGO test masses when imaged off-axis
Themann, Wm. A. (Death, 1907-06-06)
No full textAddress: 769 SummitAge at death: 268/Pg 65/1907/M W S/City/Dr. L. E. Cook/A H. Moormann/St. Mary'sOriginal record filed in drawer labeled 'TEHR-THICKE'
Issledovanie nad stroeniem cist Trichinella spiralis pri pomoshhi elektronnogo mikroskopa
No full textMorphologische und biochemische Veränderungen an Ascites-Tumorzellen der Maus nach Einwirkung von Mitomycin C
No full textMena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy
No full textBACKGROUND: In the heart, cytoplasmic actin networks are thought to have important roles in mechanical support, myofibrillogenesis, and ion channel function. However, subcellular localization of cytoplasmic actin isoforms and proteins involved in the modulation of the cytoplasmic actin networks are elusive. Mena and VASP are important regulators of actin dynamics. Due to the lethal phenotype of mice with combined deficiency in Mena and VASP, however, distinct cardiac roles of the proteins remain speculative. In the present study, we analyzed the physiological functions of Mena and VASP in the heart and also investigated the role of the proteins in the organization of cytoplasmic actin networks.
RESULTS: We generated a mouse model, which simultaneously lacks Mena and VASP in the heart. Mena/VASP double-deficiency induced dilated cardiomyopathy and conduction abnormalities. In wild-type mice, Mena and VASP specifically interacted with a distinct αII-Spectrin splice variant (SH3i), which is in cardiomyocytes exclusively localized at Z- and intercalated discs. At Z- and intercalated discs, Mena and β-actin localized to the edges of the sarcomeres, where the thin filaments are anchored. In Mena/VASP double-deficient mice, β-actin networks were disrupted and the integrity of Z- and intercalated discs was markedly impaired.
CONCLUSIONS: Together, our data suggest that Mena, VASP, and αII-Spectrin assemble cardiac multi-protein complexes, which regulate cytoplasmic actin networks. Conversely, Mena/VASP deficiency results in disrupted β-actin assembly, Z- and intercalated disc malformation, and induces dilated cardiomyopathy and conduction abnormalities
Elektronenmikroskopisch-histologische Untersuchungen über die Gewebswirkung verschiedener SiO2-Formen
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