395 research outputs found
Aufbau und Test eines Detektorsystems zum Koinzidenznachweis von Ionen und Photonen für die kollineare Laserspektroskopie am TRIGA-Forschungsreaktor [30.06.2010]
No full textOnTEAM metadata: GDSID: DOC-2010-Oct-71; Attribute ID: LIBRARY-thesis_diplom-2010-005; Title: [GSI Dipl 2010-03] Aufbau und Test eines Detektorsystems zum Koinzidenznachweis von Ionen und Photonen für die kollineare Laserspektroskopie am TRIGA-Forschungsreaktor [30.06.2010]; Author(s): Sieber, Bastian; Corporate author(s): ; Publication date: 20101014; Creator: manton; Creation date: 14.10.2010 15:32:56; Change date: 31.01.2011 17:45:03; Access: Welt; Attribute type: Thesis.Diplom; Directory path: ['GSI Publications', 'GSI as Publisher']; Attribute path: ['Infrastructure', 'Library and Documentation', 'thesis_diplom', 'Added in 2010']; File name(s): ['DOC-2010-Oct-71-1.pdf']; File title(s): ['']; File access: ['GSI-intern'
True Style: The History & Principles of Classic Menswear
No full textG. Bruce Boyer, men’s fashion editor and author of True Style: The History & Principles of Classic Menswear, discussed contemporary men’s dress and its history, styles, principles, and trends. He was joined by Pulitzer Prize- winning journalist Jonathan Capehart; New York Times cultural reporter Guy Trebay, and Michael Bastian; and MFIT Deputy Director Patricia Mears
Liječenje dodatnim beta-blokatorima i/ili glukokortikoidima kod tireotoksične oluje: Razlike u ishodu
No full textObjectives: As the main objective of this study, the role of glucocorticoids as adjunctive therapy in the treatment of thyrotoxic crisis was investigated. The study investigated whether the additional administration of glucocorticoids, either alone or in combination with beta-blockers, can accelerate the normalisation of thyroid hormone levels (FT3 and FT4). The causal objective was to evaluate the differences in response to treatment between patients receiving propylthiouracil (PTU) and those treated with thiamazole and to analyse the influence of beta-blockers and glucocorticoids on the respective therapy. Methods: The analysis was retrospective and included 70 patients who were admitted to Coburg Hospital between 2018 and 2022 with a Burch-Wartofsky score of more than 25. All patients were treated with either PTU or thiamazole and were categorised according to the use of concomitant medications: no additional therapy, glucocorticoids only, beta-blockers only or both. Clinical data were collected using electronic records, and statistical comparisons were performed using Kruskal-Wallis and Mann-Whitney U tests, with a significance level of p < 0.05. Results: There was a trend towards faster biochemical recovery in patients receiving glucocorticoids alone or in combination. In the overall population, thyroid hormone levels normalised on average after 6.0 days in patients treated with glucocorticoids alone, which was faster than in patients treated with beta-blockers alone (10.8 days) or without additional therapy (21.0 days). The shortest time to normalisation was observed in patients receiving both glucocorticoids and beta-blockers (7.9 days). In patients who were pretreated with glucocorticoids prior to hospitalisation, the average time to euthyroidism was only 5.3 days. Although statistical significance was not achieved due to the small size of the subgroups, these trends suggest that glucocorticoids as add-on therapy may play a particularly important role in accelerating hormonal stabilisation, especially in PTU-based treatment protocols. Conclusion: The findings support the hypothesis that glucocorticoids represent a valuable component of early and targeted intervention in the treatment of thyrotoxic crises. While the data indicate a notable benefit in PTU-based regimens, the benefit of glucocorticoids in thiamazole-treated patients remains less conclusive, partly due to the absence of glucocorticoid monotherapy in this group. Further studies with larger sample sizes are needed to confirm these observations and to clarify the role of glucocorticoids in different antithyroid drug contexts.Svrha istraživanja: Glavni cilj ovog istraživanja bio je ispitati ulogu glukokortikoida kao dodatne terapije u liječenju tireotoksične krize. Istraživalo se može li dodatna primjena glukokortikoida, bilo samostalno ili u kombinaciji s beta-blokatorima, ubrzati normalizaciju razine hormona štitnjače (FT3 i FT4). Poseban cilj bio je procijeniti razlike u odgovoru na liječenje između pacijenata liječenih propiltioracilom (PTU) i onih koji su primali tiamazol, te analizirati utjecaj beta-blokatora i glukokortikoida na navedene terapije. Metode: Analiza je provedena retrospektivno i obuhvatila je 70 pacijenata koji su bili hospitalizirani u bolnici Coburg u razdoblju od 2018. do 2022. godine s Burch-Wartofsky rezultatom većim od 25. Svi pacijenti liječeni su PTU-om ili tiamazolom te su razvrstani prema dodatnoj terapiji: bez dodatne terapije, samo glukokortikoidi, samo beta-blokatori ili kombinacija oboje. Klinički podaci prikupljeni su putem elektroničke dokumentacije, a statističke usporedbe provedene su Kruskal-Wallis i Mann-Whitney U testovima, uz razinu značajnosti p < 0,05. Rezultati: Uočen je trend bržeg biokemijskog oporavka kod pacijenata koji su primali glukokortikoide samostalno ili u kombinaciji. U ukupnoj populaciji, razine hormona štitnjače normalizirale su se u prosjeku nakon 6,0 dana kod pacijenata liječenih isključivo glukokortikoidima, što je brže u usporedbi s pacijentima liječenima isključivo beta-blokatorima (10,8 dana) ili bez dodatne terapije (21,0 dan). Najkraće vrijeme do normalizacije zabilježeno je kod pacijenata koji su primali glukokortikoide i beta-blokatore zajedno (7,9 dana). Kod pacijenata koji su već prije hospitalizacije bili liječeni glukokortikoidima, prosječno vrijeme do postizanja eutiroidnog stanja iznosilo je samo 5,3 dana. Iako nije postignuta statistička značajnost zbog male veličine podskupina, ovi trendovi sugeriraju da glukokortikoidi kao dodatna terapija mogu igrati posebno važnu ulogu u ubrzavanju hormonske stabilizacije, osobito u protokolima liječenja temeljenim na PTU-u. Zaključak: Rezultati podržavaju hipotezu da glukokortikoidi predstavljaju vrijedan element rane i ciljanje intervencije u liječenju tirotoksičnih kriza. Dok podaci ukazuju na značajnu korist unutar PTU-temeljenih režima, korist glukokortikoida kod pacijenata liječenih tiamazolom ostaje manje jasna, djelomično zbog činjenice da u toj skupini nije primjenjivana monoterapija glukokortikoidima. Potrebna su daljnja istraživanja s većim brojem ispitanika kako bi se potvrdila ova zapažanja i razjasnila uloga glukokortikoida u različitim kontekstima liječenja antitiroidnim lijekovima
Liječenje dodatnim beta-blokatorima i/ili glukokortikoidima kod tireotoksične oluje: Razlike u ishodu
No full textObjectives: As the main objective of this study, the role of glucocorticoids as adjunctive therapy in the treatment of thyrotoxic crisis was investigated. The study investigated whether the additional administration of glucocorticoids, either alone or in combination with beta-blockers, can accelerate the normalisation of thyroid hormone levels (FT3 and FT4). The causal objective was to evaluate the differences in response to treatment between patients receiving propylthiouracil (PTU) and those treated with thiamazole and to analyse the influence of beta-blockers and glucocorticoids on the respective therapy. Methods: The analysis was retrospective and included 70 patients who were admitted to Coburg Hospital between 2018 and 2022 with a Burch-Wartofsky score of more than 25. All patients were treated with either PTU or thiamazole and were categorised according to the use of concomitant medications: no additional therapy, glucocorticoids only, beta-blockers only or both. Clinical data were collected using electronic records, and statistical comparisons were performed using Kruskal-Wallis and Mann-Whitney U tests, with a significance level of p < 0.05. Results: There was a trend towards faster biochemical recovery in patients receiving glucocorticoids alone or in combination. In the overall population, thyroid hormone levels normalised on average after 6.0 days in patients treated with glucocorticoids alone, which was faster than in patients treated with beta-blockers alone (10.8 days) or without additional therapy (21.0 days). The shortest time to normalisation was observed in patients receiving both glucocorticoids and beta-blockers (7.9 days). In patients who were pretreated with glucocorticoids prior to hospitalisation, the average time to euthyroidism was only 5.3 days. Although statistical significance was not achieved due to the small size of the subgroups, these trends suggest that glucocorticoids as add-on therapy may play a particularly important role in accelerating hormonal stabilisation, especially in PTU-based treatment protocols. Conclusion: The findings support the hypothesis that glucocorticoids represent a valuable component of early and targeted intervention in the treatment of thyrotoxic crises. While the data indicate a notable benefit in PTU-based regimens, the benefit of glucocorticoids in thiamazole-treated patients remains less conclusive, partly due to the absence of glucocorticoid monotherapy in this group. Further studies with larger sample sizes are needed to confirm these observations and to clarify the role of glucocorticoids in different antithyroid drug contexts.Svrha istraživanja: Glavni cilj ovog istraživanja bio je ispitati ulogu glukokortikoida kao dodatne terapije u liječenju tireotoksične krize. Istraživalo se može li dodatna primjena glukokortikoida, bilo samostalno ili u kombinaciji s beta-blokatorima, ubrzati normalizaciju razine hormona štitnjače (FT3 i FT4). Poseban cilj bio je procijeniti razlike u odgovoru na liječenje između pacijenata liječenih propiltioracilom (PTU) i onih koji su primali tiamazol, te analizirati utjecaj beta-blokatora i glukokortikoida na navedene terapije. Metode: Analiza je provedena retrospektivno i obuhvatila je 70 pacijenata koji su bili hospitalizirani u bolnici Coburg u razdoblju od 2018. do 2022. godine s Burch-Wartofsky rezultatom većim od 25. Svi pacijenti liječeni su PTU-om ili tiamazolom te su razvrstani prema dodatnoj terapiji: bez dodatne terapije, samo glukokortikoidi, samo beta-blokatori ili kombinacija oboje. Klinički podaci prikupljeni su putem elektroničke dokumentacije, a statističke usporedbe provedene su Kruskal-Wallis i Mann-Whitney U testovima, uz razinu značajnosti p < 0,05. Rezultati: Uočen je trend bržeg biokemijskog oporavka kod pacijenata koji su primali glukokortikoide samostalno ili u kombinaciji. U ukupnoj populaciji, razine hormona štitnjače normalizirale su se u prosjeku nakon 6,0 dana kod pacijenata liječenih isključivo glukokortikoidima, što je brže u usporedbi s pacijentima liječenima isključivo beta-blokatorima (10,8 dana) ili bez dodatne terapije (21,0 dan). Najkraće vrijeme do normalizacije zabilježeno je kod pacijenata koji su primali glukokortikoide i beta-blokatore zajedno (7,9 dana). Kod pacijenata koji su već prije hospitalizacije bili liječeni glukokortikoidima, prosječno vrijeme do postizanja eutiroidnog stanja iznosilo je samo 5,3 dana. Iako nije postignuta statistička značajnost zbog male veličine podskupina, ovi trendovi sugeriraju da glukokortikoidi kao dodatna terapija mogu igrati posebno važnu ulogu u ubrzavanju hormonske stabilizacije, osobito u protokolima liječenja temeljenim na PTU-u. Zaključak: Rezultati podržavaju hipotezu da glukokortikoidi predstavljaju vrijedan element rane i ciljanje intervencije u liječenju tirotoksičnih kriza. Dok podaci ukazuju na značajnu korist unutar PTU-temeljenih režima, korist glukokortikoida kod pacijenata liječenih tiamazolom ostaje manje jasna, djelomično zbog činjenice da u toj skupini nije primjenjivana monoterapija glukokortikoidima. Potrebna su daljnja istraživanja s većim brojem ispitanika kako bi se potvrdila ova zapažanja i razjasnila uloga glukokortikoida u različitim kontekstima liječenja antitiroidnim lijekovima
Monitoring biodegradation capacity of organic pollutants in the environment
No full textMicro-organismen zijn in staat om organische verbindingen om te zetten in minder schadelijke stoffen en spelen daarom een belangrijke rol bij het opruimen van milieuvervuiling. Voor beleidsmakers, landgebruikers en landeigenaren is het belangrijk dat er bij milieuverontreiniging goed toezicht wordt gehouden op de biologische afbraakprocessen en dat deze goed worden beheerst. Aangezien microbiële activiteit in het milieu wordt beïnvloed door diverse fysische, geochemische en biologische factoren, is nauwkeurige kennis van het afbraakproces hierbij noodzakelijk. In dit promotieonderzoek wordt de relatie tussen geochemische condities en de biologische afbraakcapaciteit van micro-organismen in het milieu beschreven, inclusief methoden om de activiteit en metabole functies van deze micro-organismen in het milieu te mete
A study of "The Neverending Story" as an allegory of creative writing: The figures of reader and writer in Bastian
No full textEn este trabajo se realiza un análisis semántico-ficcional de La historia interminable de Michael Ende (1979). La hipótesis de partida supone considerar la obra como una alegoría del proceso de escritura creativa, que engloba la lectura previa y el propio proceso de escritura. Se estudia este simbolismo en el protagonista, Bastián, que encarna las figuras del lector y el autor tanto de forma literal en el texto como de forma alegóricaIn this work I perform a semantic-fictional analysis of The Neverending Story, by Michael Ende (1979). My starting hypothesis is to consider the novel as an allegory of the creative writing process. I study this symbolism in the principal character, Bastian, who incarnate the figures of reader and author in the text, literally and alegoricall
Author Biographies
No full textPhilipp-Bastian Brutscher is Senior Economist in the Economics Department of the European Investment Bank (EIB) where he is principally responsible for the EIB Investment Survey, a large-scale survey of corporate investment activities. Philipp acts as the focal point for the Department’s analytical work on business and infrastructure investment activities. He holds a Master’s and PhD degree from the University of Cambridge. Rocco Luigi Bubbico is Policy Advisor in the EIB Permanent R..
Sport as an integration tool for unaccompanied minor refugees : a project in Fürstenfeld
No full textDie enormen Flüchtlingsströme in Europa haben die Politik und die Gesellschaft veranlasst sich vermehrt mit dem Thema der Integration und erfolgreicher Integrationsmaßnahmen zu beschäftigen. Diese Arbeit befasst sich mit der Frage, inwieweit Sport einen Beitrag zur Integration leisten kann. Dabei wird der Fokus auf die Zielgruppe der unbegleiteten minderjährigen Flüchtlinge gesetzt. Auf theoretischer Ebene werden einleitend die sozialen sowie politischen Aspekte hinsichtlich Flucht und Asyl bearbeitet, unter anderem werden unterschiedliche Fluchtmotive, das Asylverfahren in Österreich und aktuelle Integrationsmaßnahmen behandelt. Ebenso werden verschiedene theoretische Integrationskonzepte sowie die Potenziale von Sport als Mittel der Integration aufgezeigt. Die theoretischen Ansätze und Erkenntnisse fließen in weiterer Folge in ein vom Autor initiiertes Sportprojekt für unbegleitete minderjährige Flüchtlinge ein. Dabei werden das Konzept des Projekts, die Organisationsmaßnahmen, die Durchführung sowie die Erkenntnisse und Erfahrungen beschrieben und reflektiert.The enormous streams of refugees in Europe caused politics and the society to deal increasingly with the reoccurring topic of integration and successful integration measures. This thesis deals with the question in what way sports can contribute towards integration. The focus is on the target group of unaccompanied minor refugees. In the beginning the social and political aspects regarding the flight and the asylum are worked on, there will be mentioning of different motives for refugees to leave their country, the process of applying for Asylum in Austria and current measures for integrating refugees amongst others. Also the thesis will reveal different theoretic integration concepts as well as the potential of sports to be used as an integration tool. The theoretical approaches and findings are then incorporated into a sports project initiated by the author for unaccompanied minor refugees. With doing so the concept of the project, the measures for organizing it, the execution as well as the knowledge and experiences are described.vorgelegt von Bastian JedliczkaAbweichender Titel laut Übersetzung des Verfassers/der VerfasserinZusammenfassungen in Deutsch und EnglischDiplomarbeit Karl-Franzens-Universität Graz 2018 2.03
Capacity adjustment factors for connected and automated vehicles in the Highway capacity manual: phase 1 and 2 final report : pooled fund study led by Oregon DOT
No full textThis project's objective was to develop capacity adjustment factors (CAFs) for connected and automated vehicles (CAVs) at different levels of market penetration to allow the HCM to be used to analyze CAV applications on freeways and urban streets. The primary approach to this problem was through an "agent-based" (i.e., fully customizable vehicle and driver behavior) simulation modeling framework in which CAV and non-CAV behavior could be modeled differently. The products of this research are highway capacity adjustment lookup tables and figures for different transportation system elements (e.g., freeways, roundabouts, signalized intersections) at different levels of CAV market penetration, and example scenarios demonstrating the application of the CAFs to planning studies.Report -- Appendix A.by Bastian Schroeder, PhD, PE, Abby Morgan, PhD, PE, Paul Ryus, PE, Burak Cesme, PhD, Apoorba Bibeka, Lee Rodegerdts, PE, and Jiaqi Ma, PhD ; for Oregon Department of Transportation, Research Section and Federal Highway Administration.Title from PDF title page (viewed on April 14, 2022)."FHWA-OR-RD-22-11"--Technical report documentation page.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Sponsored by Oregon Dept. of Transportation, Research Section, Federal Highway Admin.Mode of access: Internet from the Oregon Government Publications Collection.Text in English.Final Repor
Re-printing architectural heritage: The Hippolytuskerk and Mauritshuis projects
No full textAdditive Manufacturing (commonly known as 3D printing) technology has become a global phenomenon. In the domain of heritage, 3D printing can be seen as a time and cost-efficient method for restoring vulnerable architectural structures. The technology can also provide an opportunity to reproduce missing or destroyed cultural heritage or to express lost appearances, in the cases of conflicts or environmental threats. Researchers from TU Delft have led two experimental projects published respectively in Innovative Materials (volume 6 2018 and volume 1 2019). The projects show the challenges and possibilities of contemporary 3D printing technology for the 3D printing of heritage. The first one, a 4TU-project called ‘Re-printing architectural heritage’ focused on the Hippolytuskerk in the Dutch village of Middelstum. There, the group of researchers tested available technologies to reproduce a mural on a section of one of the church’s vault with maximum possible fidelity to material, colours and local microstructures. Simultaneously, a second project was conducted at the Mauritshuis at The Hague. This to investigate and to discuss the potential of reprinting historical spaces as a copy.History, Form & AestheticsDesign of Construtio
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