57 research outputs found
Il fiume Reno e la rete fluviale del Ferrarese
No full textIl contributo ricostruisce le vicende legate alla regolazione del fiume Reno, con particolare attenzione ai secoli XVII e XVIII, nel corso dei quali numerosi matematici intervennero nel dibattito, prospettando possibili soluzioni. Tra gli interventi più significativi vi sono la visita Conti (1761-62), coordinata dal matematico toscano Tommaso Perelli, e la visita dei tre periti (1765-72), sovrintesa dal gesuita milanese Giovanni Antonio Lecchi
I matematici e le nuove linee per il Reno (1692-1772)
No full textIl problema della regolazione del corso del fiume Reno nella pianura tra Bologna e Ferrara, tornato di grande attualità dopo gli eventi sismici del maggio 2012, è stato lungamente dibattuto nel corso dei passati secoli. In questo lavoro viene fornito un quadro delle principali vicende che hanno caratterizzato il corso del Reno tra il 1692 ed il 1772, mettendo in luce l’apporto fornito dai più importanti matematici italiani del tempo nella vicenda. Gli estremi temporali coincidono con quelli di due importanti visite alle acque, la prima, nota come Visita D’Adda Barberini, dal nome dei due cardinali che la sovrintesero, vide l’attiva partecipazione del matematico bolognese Domenico Guglielmini. Alla seconda, conclusasi nel 1772 e ricordata come Visita dei tre periti, presero parte tre importanti scienziati, tra i quali spicca quello del matematico e idrostatico milanese Giovanni Antonio Lecchi. Particolare attenzione è stata posta sulla cosiddetta Visita Conti (1761-62), alla quale presero parte i matematici Gabriele Manfredi, bolognese, Teodoro Bonati, ferrarese, oltre al milanese Paolo Frisi e al toscano Leonardo Ximenes
"Ten-point" 3D cephalometric analysis using low-dosage cone beam computed tomography
No full textObjective: The aim of this study was to combine the huge amount of information of low dose Cone Beam CT with a cephalometric simplified protocol thanks to the latest informatics aids.Lateral cephalograms are two-dimensional (2-D) radiographs that are used to represent three-dimensional (3-D) structures. Cephalograms have inherent limitations as a result of distortion, super imposition and differential magnification of the craniofacial complex. This may lead to errors of identification and reduced measurement accuracy.The advantages of CBCT over conventional CT include low radiation exposure, imaging quality improvement, potentially better access, high spatial resolution and lower cost. Materials and methods: This study assessed cephalometric 2D and 3D measurements and the analysis of CBCT cephalograms of the volume and centroid of the maxilla and mandible, in 10 clinical cases. Results: With a few exceptions the linear and angular cephalometric measurements obtained from CBCT and from conventional cephalograms did not differ statistically (p>0.01). There was a correlation between the variation in the skeletal malocclusion and growth direction of the jaws, and the variation in the spatial position (x, y, z) of the centroids and their volumes (p<0.01). Conclusions: The 3D cephalometric analysis is easier to interpret than 2D cephalometric analysis. In contrast to those made on projective radiographies, the angular and linear measurements detected on 3D become real, moreover the fewest points to select and the automatic measurements made by the computer drastically reduced human error, for a much more reliable reproducible and repeatable diagnosis. © 2010 Società Italiana di Ortodonzia SIDO
Agreement Between Potential Drug Interactions Identified by an Electronic Tooland Clinical Judgment: INTERcheck® versus Physicians
No full textLiver Involvement in Patients with Rare MBOAT7 Variants and Intellectual Disability: A Case Report and Literature Review
No full textThe membrane-bound O-acyltransferase domain-containing 7 (MBOAT7) protein is an acyltransferase catalyzing arachidonic acid incorporation into lysophosphatidylinositol. Patients with rare, biallelic loss-of-function variants of the MBOAT7 gene display intellectual disability with neurodevelopmental defects. The rs641738 inherited variant associated with reduced hepatic MBOAT7 expression has been linked to steatotic liver disease susceptibility. However, the impact of biallelic loss-of-function MBOAT7 variants on liver disease is not known. We report on a 2-year-old girl with MBOAT7-related intellectual disability and steatotic liver disease, confirming that MBOAT7 loss-of-function predisposes to liver disease
Predictors of controlled attenuation parameter in metabolic dysfunction
No full textBackground & Aims: Hepatic fat content can be non-invasively estimated by controlled attenuation parameter (CAP) during transient elastography. The aim of this study was to examine the determinants and predictors of CAP values in individuals with metabolic dysfunction. Methods: We enrolled 1230 consecutive apparently healthy individuals (Liver-Bible-2022 cohort) with ≥3 metabolic dysfunction features. CAP was measured by Fibroscan. CAP determinants and predictors were identified using backward stepwise analysis and introduced in generalized linear models. Results: Participants were predominantly males (82.9%), mean age was 53.8 ± 6.4 years, 600 (48.8%) had steatosis (CAP ≥ 275 dB/m), and 27 had liver stiffness measurement (LSM) ≥ 8 kPa. CAP values correlated with LSM (p < 10−22). In multivariable analysis, fasting insulin and abdominal circumference (AC) were the main determinants of CAP (p < 10−6), together with body mass index (BMI; p < 10−4), age, diabetes, triglycerides, ferritin, and lower HDL and thyroid stimulating hormone (TSH; p < 0.05 for all). In a subset of 592 participants with thyroid hormone measurement, we found an association between higher free triiodothyronine levels, correlating with lower TSH, and CAP values, independent of TSH and of levothyroxine treatment (p = 0.0025). A clinical CAP score based on age, BMI, AC, HbA1c, ALT, and HDL predicted CAP ≥ 275 dB/m with moderate accuracy (AUROC = 0.73), which was better than that of the Fatty Liver Index and of ALT (AUROC = 0.70/0.61, respectively) and validated it in multiple cohorts. Conclusion: Abdominal adiposity and insulin resistance severity were the main determinants of CAP in individuals with metabolic dysfunction and may improve steatotic liver disease risk stratification. CAP values were modulated by the hypophysis-thyroid axis
L'accertamento di questioni nell'arbitrato: la perizia contrattuale
No full textIn this work, the Author reconstructs and analyzes the institutional practice of perizia contrattuale. It can be called also expert determination, and It consists in a mechanism through which two subjects commission one or more third parties with specific technical-scientific skills – so called “periti,” field-experts – to verify a relevant technical matter in a legal relationship or a controversy. The verification is considered binding by the parties involved.
The “history” about the phenomenon in question shows that it has been always compared to arbitraggio and arbitration.
In short, the work is organized in six chapters.
The first chapter begins with a short investigation into the historical context about arbitration and arbitraggio, in particular in the roman and medieval law.
In the second chapter, the Author explains the main theories about perizia contrattuale; in this chapter there is also an evaluation about the irregular arbitration and a short investigation into institutions in other legal systems which have the same characteristics of perizia.
The third chapter analyzes Spanish system of arbitration law; in this system perizia contrattuale is considered something different to arbitration.
In the fourth chapter, that is the heart of the work, after a description of the main differences between perizia contrattuale and arbitraggio, the Author compares perizia contrattuale to arbitration. He analyzes also the contract of ascertainment, and finally he explains that perizia contrattuale is a particular kind of irregular arbitration; perizia and arbitration differ only with regards to the object of verification.
In the fifth chapter, putting together the insights derived from the evolution of court decisions and making reference to the legal doctrine that has produced most in-depth studies of the phenomenon, the Author proposes the regulation of the phenomenon in question.
In the last chapter there is an investigation into the contestation of perizia contrattuale.In this work, the Author reconstructs and analyzes the institutional practice of perizia contrattuale. It can be called also expert determination, and It consists in a mechanism through which two subjects commission one or more third parties with specific technical-scientific skills – so called “periti,” field-experts – to verify a relevant technical matter in a legal relationship or a controversy. The verification is considered binding by the parties involved.
The “history” about the phenomenon in question shows that it has been always compared to arbitraggio and arbitration.
In short, the work is organized in six chapters.
The first chapter begins with a short investigation into the historical context about arbitration and arbitraggio, in particular in the roman and medieval law.
In the second chapter, the Author explains the main theories about perizia contrattuale; in this chapter there is also an evaluation about the irregular arbitration and a short investigation into institutions in other legal systems which have the same characteristics of perizia.
The third chapter analyzes Spanish system of arbitration law; in this system perizia contrattuale is considered something different to arbitration.
In the fourth chapter, that is the heart of the work, after a description of the main differences between perizia contrattuale and arbitraggio, the Author compares perizia contrattuale to arbitration. He analyzes also the contract of ascertainment, and finally he explains that perizia contrattuale is a particular kind of irregular arbitration; perizia and arbitration differ only with regards to the object of verification.
In the fifth chapter, putting together the insights derived from the evolution of court decisions and making reference to the legal doctrine that has produced most in-depth studies of the phenomenon, the Author proposes the regulation of the phenomenon in question.
In the last chapter there is an investigation into the contestation of perizia contrattuale.LUISS PhD Thesi
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