683 research outputs found
Caterina Colombini, o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi
No full textIn this essay the author demonstrates that it is possible to “reconstruct” the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini’s cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni’s biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina’s hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed
Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts.
No full textDi Napoli P, Taccardi AA, Grilli A, De Lutiis MA, Barsotti A, Felaco M, De Caterina R. Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts. Cardiovasc Res. 2005 Jun 1;66(3):462-71. Epub 2005 Mar 2.
Laboratory of Experimental Cardiology, Department of Clinical Sciences and Bioimaging, and Center of Excellence of Aging, G. d'Annunzio University, Chieti, Italy.
OBJECTIVE: Due to reported modulatory effects of statins on nitric oxide synthase (NOS) expression, we tested the hypothesis of protective effects of in vivo chronic treatment with rosuvastatin, a novel 3-hydroxy-3-methyl-glutaryl coenzyme A-reductase inhibitor, on ischemia-reperfusion injury, and investigated mechanisms involved.
METHODS: After 3 weeks of in vivo treatment with rosuvastatin (0.2-20 mg/kg/day) or placebo, excised hearts from Wistar rats were subjected to 15 min global ischemia and 22-180 min reperfusion. We evaluated creatine-phosphokinase and nitrite levels in the coronary effluent, heart weight changes, microvascular permeability (extravasation of fluoresceine-labeled albumin), ultrastructural alterations, and the expression of endothelial (e) and inducible (i) nitric oxide synthase (NOS) (by reverse-transcription polymerase chain reaction and Western blotting).
RESULTS: Rosuvastatin 0.2 and 2 mg/kg/day significantly reduced myocardial damage and vascular hyperpermeability, concomitant with a reduction in endothelial and cardiomyocyte lesions. At 2 mg/kg/day, rosuvastatin significantly increased eNOS mRNA and protein compared with untreated hearts, and conversely decreased iNOS mRNA and protein, as well as nitrite production after ischemia-reperfusion. The addition of the NOS inhibitor N(omega)-nitro-L-arginine methylester (L-NAME, 30 micromol/L) significantly reduced cardioprotection against ischemia-reperfusion.
CONCLUSIONS: Chronic treatment with rosuvastatin before ischemia reduces ischemia-reperfusion injury and prevents coronary endothelial cell and cardiomyocyte damage by NO-dependent mechanisms
Temperamento Infantile, Disattenzione e Iperattività. Un Confronto Tra Genitori e Insegnanti
No full textL’interazione reciproca tra temperamento infantile, comportamento adulto e risposte infantili ad esso ha effetto sullo sviluppo del bambino, in generale e nel contesto scolastico (Lerner e Lerner, 1983; Chess e Thomas, 1987; Matheny, 1989; Vermigli e Attili, 2001). Lo studio esplora le valutazioni di insegnanti e genitori su temperamento e comportamento di 49 bambini dell’ultimo anno di scuola dell’infanzia, attraverso l’uso di due strumenti: i Questionari Italiani del Temperamento Infantile (QUIT; Axia, 2002) e le Conners’ Rating Scale-R (CTRS-R, vers. it. Nobile et al., 2007). Le valutazioni di genitori e insegnanti sono significativamente diverse per attività motoria (QUIT; F=21.5, p=.000), emozionalità positiva (QUIT; F=4.75, p=.032) e indice ADHD (CTRS-R; F=21.6, p=.000). Inoltre, nei pattern di correlazione, mentre le valutazioni degli insegnanti su ADHD, iperattività/impulsività e disattenzione (CTRS-R) sono significativamente associate alla maggior parte delle caratteristiche temperamentali (.38<r<.78; p<.01), quelle dei genitori lo sono solo con attività motoria ed emozioni negative (.36<r<.50; p<.01). Saranno discusse implicazioni teoriche e applicative
Effect of hydrotermally processed cereals on the performance of weaned piglets
No full textAntisecretory factor (AF) is an endogenous protein that has shown to be a potent inhibitor of intestinal fluid secretion and inflammation. AF content in sows' milk is important for protection against neonatal diarrhoea in suckling piglets. Feeding specific hydrothermally processed cereals (HPC) has proven to increase the plasma level of AF and to be helpful in counteracting diarrhoea in domestic animals. The aim of the study was to investigate the effects of an AF-inducing diet on piglets' growth performance and intestinal mucos
Chapter Caterina Colombini, o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi
No full textIn this essay the author demonstrates that it is possible to “reconstruct” the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini’s cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni’s biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina’s hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed
Dairy by-products valorization with biomethane and biohydrogen production through lactose fermentation in AnMBR
No full textDairy liquid by-products after cheese production (e.g. whey for hard cheese, “scotta” for ricotta, brine for mozzarrella, lactose syrup after milk standardization by ultrafiltration) represent a potential revenue for food factories where large scale industrial production is implemented, as additional ingredients may be recovered, transformed and sold as separate products. Still, these by-products may also represent a problem for small/medium size factories or in areas that are far from ingredients transformation platforms: complete processing of smaller volumes or shipping liquids over long distances is not convenient. By-products are often disposed as waste, generating unproductive cost for the factory and worsening environmental footprint. In this paper a simple closed loop solution is evaluated for full valorization of those by-products, based on the technologies of: protein separation/concentration and anaerobic treatment of the lactose containing permeate
Caterina Tarabotti Unveiled
No full textCaterina Tarabotti (1615–1693) never identified herself as a painter in contemporary
documents or claimed authorship of any picture with her signature. She would have
surely joined the ranks of the many anonymous women painters of her time, were
it not for the art critic and historian Marco Boschini (1602–1681). In his La Carta
del Navegar Pitoresco (1660), Boschini was the first to notice Caterina’s talents and
provide information about her life.1
Alluding to her namesake saint and surname,
Boschini infused the painter’s biography with lyric flair. A light coming out of the
Varotari workshop, Caterina was, according to Boschini, a virgin very gifted in
painting. She herself honored art with her achievements, which came effortlessly.
Comparing her to a silver lamp that never burns out, the author, with a sense of
optimism, concluded that Caterina would live forever and her name would bear
eternal light and splendor
Engineering dielectric materials for high-performance organic light emitting transistors (Olets)
No full textFunding Information: The Author thanks the support from Academy of Finland Flagship Program (Grant No.: 320167, PREIN). Author thanks Gianluca Generali and many colleagues in ETC srl and CNR-ISMN (Italy) for valuable discussions on organic light emitting transistors during the years. Funding Information: Acknowledgments: The Author thanks the support from Academy of Finland Flagship Program (Grant No.: 320167, PREIN). Author thanks Gianluca Generali and many colleagues in ETC srl and CNR-ISMN (Italy) for valuable discussions on organic light emitting transistors during the years. Publisher Copyright: © 2021 by the author. Licensee MDPI, Basel, Switzerland.Organic light emitting transistors (OLETs) represent a relatively new technology platform in the field of optoelectronics. An OLET is a device with a two-fold functionality since it behaves as a thin-film transistor and at the same time can generate light under appropriate bias conditions. This Review focuses mainly on one of the building blocks of such device, namely the gate dielectrics, and how it is possible to engineer it to improve device properties and performances. While many findings on gate dielectrics can be easily applied to organic light emitting transistors, we here concentrate on how this layer can be exploited and engineered as an active tool for light manipulation in this novel class of optoelectronic devices.Peer reviewe
Erratum to: Monitoring antigenic protein integrity during glycoconjugate vaccine synthesis using capillary electrophoresis-mass spectrometry (Analytical and Bioanalytical Chemistry, (2016), 408, 22, (6123-6132), 10.1007/s00216-016-9723-5)
No full textUnfortunately the name of Luciano Piubelli was missing as co-author of this contribution. The correct list of authors is: Sara Tengattini, Elena Domínguez-Vega, Luciano Piubelli, Caterina Temporini, Marco Terreni, Govert W. Somse
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