405 research outputs found
COMPARISON OF FIELD CALCULATIONS AND MEASUREMENTS OF A SPECTROMETER MAGNET
The magnetic spectrometer of the CERN experiment NA48 uses a conventional dipole magnet with a gap of 2.40 m and a field integral of 0.83 Tm, equivalent to a transverse momentum change of charged particles of 250 MeV/c. This paper introduces the magnet and compares three-dimensional calculations of the magnetic field with the measured field map
Écrire un seul livre, sans cesse renouvelé : Jorge Sempruns literarische Auseinandersetzung mit Buchenwald
The study examines Jorge Semprun´s literary reflections on his experiences made in the concentration camp of Buchenwald in "Le grand voyage" (1963), "Quel beau dimanche!" (1980), "L´écriture ou la vie" (1994) and "Le mort qu´il faut" (2001) with the aim to show the development in his retrospective treatment of the past. Therefore the texts are not considered as a unified "ecriture" but as a progressing approximation to his experiences in Buchenwald.
The study deals in narratological and poetological terms with Semprun´s growing awareness of what Buchenwald means to him: While "Le grand voyage" is deeply influenced by the authors communistic view. "Quel beau dimanche!" reflects Sempruns disconcertion caused by his awareness of the parallel existence of concentration camps in Nazi-Germany and in the Soviet Union. "L´ecriture ou la vie" and "Le mort qu´il faut", for their part, are written by an author who considers himself as survivor and witness.
This process is accompanied by Semprun´s shift to literature as a universe implying sense and creating identity. This becomes vitally important after his dissociation from communism and enables him to speak extensively about his experiences with death. Therefore Semprun´s conception of "witnessship" can be described as diametrically opposed to factual documentation. It is rather intended to function within a literary field: Only the intensive use of intertextuality allowes Semprun to comprehend Buchenwald finally as the centre of his life and as the origin of his own identity as well as to communicate his "truth" to the reader.Die Studie untersucht Jorge Sempruns literarische Gestaltung seiner Erfahrungen des Konzentrationslagers Buchenwald in "Le grand voyage (1963), "Quel beau dimanche!" (1980), "L´ecriture ou la vie" (1994) und "Le mort qu´il faut (2001). Ziel der Arbeit ist es, Entwicklungslinien und Tendenzen in der retrospektiven Auseinandersetzung und literarischen Bearbeitung des persönlich Erlebten aufzuzeigen. Demzufolge werden die Texte nicht als einheitliches Sprechen, sondern als fortschreitende erzählerische Annäherung an den miterlebten Tod von Buchenwald betrachtet.
Die narratologisch und poetologisch ausgerichtete Studie fokussiert den Bewusstwerdungsprozess, der in den Texten zum Ausdruck gelangt: Während "Le grand voyage" noch deutlich vom kommunistischen Weltbild des Autors geprägt ist, spiegelt sich in "Quel beau dimanche!" - geschrieben im Bewusstsein über die gleichzeitige Existenz nationalsozialistischer und stalinistischer Lager - die existentielle Verunsicherung Sempruns, wohingegen in "L´ecriture ou la vie" und "Le mort qu´il faut" die Selbstdefinierung als Überlebender und Zeuge dominiert.
Paralell zu dieser Entwicklung vollzieht sich Sempruns Hinwendung zur Literatur als identitäts- und sinnstiftendem Universum, das, insbesondere nach der Lossage vom Kommunismus, verstärkt in den Vordergrund rückt und erst die umfassende Sagbarkeit der Erfahrung ermöglicht. Sempruns Konzeption von Zeugenschaft steht folglich in direkter Opposition zu einem dokumentarischen Bezeugen und bewegt sich stattdessen innerhalb eines genuin literarischen Feldes. Nur durch den intensiven Einsatz intertextueller Bezugnahmen gelingt es dem Autor, die Erfahrung von Buchenwald als Zentrum seines Lebens sowie als Ursprung seines Ichs zu begreifen und diese "Wahrheit" dem Leser mitzuteilen
"Écrire un seul livre, sans cesse renouvelé"
The study examines Jorge Semprun´s literary reflections on his experiences made in the concentration camp of Buchenwald in "Le grand voyage" (1963), "Quel beau dimanche!" (1980), "L´écriture ou la vie" (1994) and "Le mort qu´il faut" (2001) with the aim to show the development in his retrospective treatment of the past. Therefore the texts are not considered as a unified "ecriture" but as a progressing approximation to his experiences in Buchenwald.
The study deals in narratological and poetological terms with Semprun´s growing awareness of what Buchenwald means to him: While "Le grand voyage" is deeply influenced by the authors communistic view. "Quel beau dimanche!" reflects Sempruns disconcertion caused by his awareness of the parallel existence of concentration camps in Nazi-Germany and in the Soviet Union. "L´ecriture ou la vie" and "Le mort qu´il faut", for their part, are written by an author who considers himself as survivor and witness.
This process is accompanied by Semprun´s shift to literature as a universe implying sense and creating identity. This becomes vitally important after his dissociation from communism and enables him to speak extensively about his experiences with death. Therefore Semprun´s conception of "witnessship" can be described as diametrically opposed to factual documentation. It is rather intended to function within a literary field: Only the intensive use of intertextuality allowes Semprun to comprehend Buchenwald finally as the centre of his life and as the origin of his own identity as well as to communicate his "truth" to the reader
The influence of cleaning solutions on the retention of overdenture attachments systems
Dental-implant-supported reconstructions provide comfort and improvements in prosthetic
function, adaptation, and stability over conventional treatment options.
The objective of this study was to evaluate the effect of different denture cleansing
solutions and their influence on the deterioration and loss of retention of overdenture
attachments in a 12-month clinical-use simulation. In this way, ten specimens each of
different brands of retentive caps made of Teflon (OT Equator® (Rhein83, Bologna, Italy),
Locator® (Zest Anchors, Escondido, CA, USA), Kerator® (KJ Meditech, Gwangiu, Republic of
Korea), and Locator R-Tx® (Zest Anchors, Escondido, CA, USA)) were immersed in five
different cleaning solutions (Kukident® (P&G Tech, Oxford Parkway, UK), Benfix®
(Laboratorios URGO S.L., Guipúzcoa, Spain), Corega® (Stafford Miller, Waterford, Ireland), and
Protefix® (Neuhofer Weiche, Parchim, Germany)), and tap water was used as the control
group, in a simulation that lasted 12 months.
Data were analyzed using two-way ANOVA and a Tukey HSD. Furthermore, a Levene Test and
Shapiro–Wilk tests were performed to assess the validation of the ANOVA assumptions. The
statistical analysis was performed using R version 4.2.2 software with the significance level
set to p < 0.05.
There were significant statistical differences between the different manufacturers regarding
the retention forces of the attachment’s retentive caps (F = 322.066, p < 0.001). For the
cleaning solution groups, different statistical results between Kukident® (P&G Tech, Oxford
Parkway, UK) (p < 0.05) and Benfix® (Laboratorios URGO S.L., Guipúzcoa, Spain) (p < 0.05)
were observed. There were no significant statistical differences between Corega® (Stafford
Miller, Ireland), Protefix® (Neuhofer Weiche, Parchim, Germany), and tap water, even though
the retention forces decreased in all of them
The Influence of Cleaning Solutions on the Retention of Overdenture Attachment Systems
Dental-implant-supported reconstructions provide comfort and improvements in prosthetic function, adaptation, and stability over conventional treatment options. The objective of this study was to evaluate the effect of different denture cleansing solutions and their influence on the deterioration and loss of retention of overdenture attachments in a 12-month clinical-use simulation. In this way, ten specimens each of different brands of retentive caps made of Teflon (OT Equator® (Rhein83, Bologna, Italy), Locator® (Zest Anchors, Escondido, CA, USA), Kerator® (KJ Meditech, Gwangiu, Republic of Korea), and Locator R-Tx® (Zest Anchors, Escondido, CA, USA)) were immersed in five different cleaning solutions (Kukident® (P&G Tech, Oxford Parkway, UK), Benfix® (Laboratorios URGO S.L., Guipúzcoa, Spain), Corega® (Stafford Miller, Waterford, Ireland), and Protefix® (Neuhofer Weiche, Parchim, Germany)), and tap water was used as the control group, in a simulation that lasted 12 months. Data were analyzed using two-way ANOVA and a Tukey HSD. Furthermore, a Levene Test and Shapiro–Wilk tests were performed to assess the validation of the ANOVA assumptions. The statistical analysis was performed using R version 4.2.2 software with the significance level set to p < 0.05. There were significant statistical differences between the different manufacturers regarding the retention forces of the attachment’s retentive caps (F = 322.066, p < 0.001). For the cleaning solution groups, different statistical results between Kukident® (P&G Tech, Oxford Parkway, UK) (p < 0.05) and Benfix® (Laboratorios URGO S.L., Guipúzcoa, Spain) (p < 0.05) were observed. There were no significant statistical differences between Corega® (Stafford Miller, Ireland), Protefix® (Neuhofer Weiche, Parchim, Germany), and tap water, even though the retention forces decreased in all of them
Comparison of the influence of different envelope maskers on neuronal representation.
<p>The graphs show the slopes of the distance curves (as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034384#pone-0034384-g004" target="_blank">Fig. 4 E,F</a>) of single cells, which were tested with different envelope maskers. Error bars indicate the mean standard error (s.e.m.) of the linear regression, each point in a graph represents a single neuron. The different cell types are indicated by different symbols (see inset). A) 0–1000 Hz vs. 0–1000 Hz notch, LN: 18, AN: 9; B) 0–1000 Hz vs. 100–500 Hz, LN: 12, AN: 5; C) 0–1000 Hz vs. 200–750 Hz, LN: 7; D) 0–1000 Hz vs. 0–100 Hz, LN: 9, AN: 13; E) 0–1000 Hz vs. 100–200 Hz, LN: 7, AN: 5; F) 0–100 Hz vs. 100–200 Hz, LN: 9, AN: 6; G) 100–500 Hz vs. 200–750 Hz, LN: 7, AN: 1.</p
An inherited mtDNA rearrangement, mimicking a single large-scale deletion, associated with MIDD and a primary cardiological phenotype
Aim: To identify the genetic cause in a previously unsolved pedigree, with mother and two daughters suffering of dilated cardiomyopathy with prevailing arrhythmic burden associated with diabetes mellitus and sensorineural hearing loss, without clear evidence of progressive external ophthalmoplegia. Methods: Several genetic tests were performed over the years including single-gene sequencing, mitochondrial DNA (mtDNA) sequencing, NGS panel for mitochondrial diseases and cardiomyopathies, clinical exome sequencing and whole exome sequencing. Specific amplifications and long-read NGS were used to evaluate mtDNA structural alterations. Results: By means of whole exome sequencing we found a novel heteroplasmic 12 kb-long single deletion in the mtDNA in all affected family members, confirmed by long-range PCR. However, a deeper investigation by long-read NGS revealed indeed the presence of rearranged mtDNA species, formed by a wild-type plus a deleted molecule. This mtDNA duplication turned out to be inherited in our pedigree and present in all tested specimens. Conclusion: While mtDNA single large-scale deletions are generally considered sporadic, few old reports described maternally inherited mtDNA duplication We suggest that mtDNA large rearrangements should be considered as possible disease causes in familial cases with unusual mitochondrial phenotypes. Long-read sequencing is useful for the detection of these variants, particularly mtDNA duplications
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