820 research outputs found
Editorial: Are glucagon-like peptide-1 receptor agonists the functional cure for patients with metabolic dysfunction-associated cirrhosis?
No full textLINKED CONTENT This article is linked to Elsaid et al paper. To view this article, visi
Engraçadinha : passagens e cortes / Nelson Rodrigues na televisão
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ExpressãoAsfalto Selvagem I e II - Engraçadinha seus amores e seus pecados foi escrito por Nelson Rodrigues, originalmente, sob a forma de folhetim, diariamente publicado no jornal Ultima Hora (1959-60), e seguindo o caminho de seus folhetins anteriores recebeu uma impressão posterior (1961) em forma de livro, "transformando-se" em romance. Em 1995, novamente, Asfalto Selvagem... migra para outro veículo da indústria cultural indo parar num seriado de televisão. Este trabalho propõe retraçar as pontes entre o folhetim como forma de literatura industrializada e a televisão como veículo da indústria cultural e como bem simbólico (na cultura brasileira), a fim de localizar Asfalto Selvagem: Engraçadinha seus amores e seus pecados em sua passagem do jornal à televisão em alguns aspectos implicados nesse processo. Em primeiro lugar, na obra de Nelson Rodrigues, Engraçadinha destaca-se em sua travessia social de gêneros e como romance-folhetim. Em segundo lugar, há uma re-montagem histórica da teledramaturgia como pano de fundo propiciador de uma exposição do folhetim de Nelson Rodrigues. Em terceiro lugar, a passagem, propriamente dita, do folhetim à imagem, se por um lado reforça o caráter conservador da TV, por outro, atualiza a transgressividade erótica presente no texto rodrigueano, já como uma adaptação ao século XX do folhetim do século XIX
Recensão ao texto: RODRIGUES, Susana (2017) - O Sistema de Informação Presidência da República Portuguesa: estudo orgânico-funcional (1910-2014). 1ª ed. Lisboa: Edições Colibri. 144 p.
No full textThe book “The Information System of the Presidency of the Portuguese Republic: organic-functional study (1910-2014)“ reflects the path of theoretical and practical experience acquired by the author, master Susana Rodrigues, during her master's degree at the University of Lisbon. The author seeks to carry out a systematic survey of the organic-functional structure of the Presidency of the Republic (1910-2014)RODRIGUES, Susana (2017) - El Sistema de Información de la Presidencia de la República Portuguesa: estudio orgánico-funcional (1910-2014). - 1ª edición - Lisboa: Colección de Ciencias de la Información; 2), 144 p.O livro “O Sistema de Informação da Presidência da República Portuguesa: estudo orgânico-funcional (1910-2014)“ traduz o trajeto de experiência teórico-prática adquirida pela autora, mestre Susana Rodrigues, durante o mestrado na Universidade de Lisboa. A autora busca efetuar o levantamento sistemático da estrutura orgânico-funcional da Presidência da República (1910-2014)
Gestionar la distancia a través de documentos: cartas que van y vienen entre la Inquisición de Madrid, Lima, Córdoba y Buenos Aires
No full textEn este trabajo abordamos la gestión de la distancia implementada por la Inquisición española, a través de cartas e informes, para llevar adelante las políticas de control,y funcionamiento de los tribunales extra europeos.Fil: Vassallo, Jaqueline Rossely. Universidad Nacional de Córdoba. Facultad de Filosofía y Humanidades; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad. Universidad Nacional de Córdoba. Centro de Investigaciones y Estudios sobre Cultura y Sociedad; Argentin
Sarcopenia evaluated by EASL/AASLD computed tomography-based criteria predicts mortality in patients with cirrhosis: A systematic review and meta-analysis.
No full textBACKGROUND & AIMS
Sarcopenia is associated with increased morbidity and mortality in patients with cirrhosis, but its definition in current literature is very heterogeneous. We performed a systematic review and meta-analysis to assess the association between mortality and sarcopenia evaluated by computed tomography (CT) in patients with cirrhosis, both overall and stratified for the criteria used to define sarcopenia.
METHODS
Medline, Embase, Scopus, and Cochrane Library were searched up to January 2023. We included studies assessing sarcopenia presence with CT scans and providing data on the risk of mortality. Adjusted hazard ratios (HRs) and 95% CIs were pooled using a random-effects model.
RESULTS
Thirty-nine studies comprising 12,827 patients were included in the meta-analysis. The summary prevalence of sarcopenia was 44% (95% CI 38-50%). The presence of sarcopenia (any definition) was an independent predictor of mortality with an adjusted HR of 2.07 (95% CI 1.81-2.36), and the result was consistent in all subgroup analyses. The prognostic role of the EASL/AASLD criteria was confirmed for the first time with an HR of 1.86 (95% CI 1.53-2.26) (n = 14 studies). The cut-offs used to define sarcopenia based on psoas muscle parameters varied among studies, thus, a subgroup analysis was not feasible. There was no substantial heterogeneity for the main estimates and no significant risk of publication bias.
CONCLUSIONS
Sarcopenia on CT is associated with a 2-fold higher risk of mortality in patients with cirrhosis. The cut-offs proposed by EASL/AASLD are prognostically relevant and should be the recommended criteria used to define sarcopenia in clinical practice.
IMPACT AND IMPLICATIONS
Sarcopenia assessed by the reference standard (computed tomography scan) is an independent predictor of mortality in patients with cirrhosis, with a 2-fold increase in the risk of death in all sensitivity analyses. This finding is particularly valid in patients from Europe and North America, and in transplant candidates. Stratifying for the parameters and cut-offs used, we confirmed for the first time the prognostic impact of the definition proposed by EASL/AASLD, supporting their use in clinical practice. Psoas muscle assessment is promising, but data are still limited and too heterogeneous to recommend its routine use at present
Nelson Rodrigues : a mulher em tres planos
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina. Centro de Comunicação e ExpressãoO presente trabalho propõe uma re-leitura da obra teatral de Nelson Rodrigues, enfocando a "mulher" como elemento-chave de suas peças. A notória relevância atribuída pelo autor às personagens femininas, fazendo-as protagonistas da maioria de suas peças. Trata-se de uma visão nova (para a época) da sensibilidade feminina, num tratamento diferenciado da mulher, com suas mazelas e frustrações. A mulher tripartida interiormente, oscilando entre os planos da realidade, memória e alucinação, de acordo com os caminhos e descaminhos do desejo, à mercê das pressões sociais e familiares - é a representante do universo feminino da dramaturgia rodriguiana. Foram destacadas três personagens para um estudo mais detalhado. Das estruturas e linguagem da obra do autor foram extraídas as bases constitutivas dessas personagens. Três momentos distintos na criação do teatro do autor; três atos em cada uma das peças (a exceção de uma); três planos no palco de vestido de noiva e na divisão interna da complexa alma feminina. Uma proposta dramatúrgica voltada para os motivos intrínsecos da existência, como o amor, a morte, o desejo, o ódio e todas as situações limítrofes
Baveno VII criteria to predict decompensation in compensated advanced chronic liver disease: still some shades of grey.
No full textAssessment of eucalypts wood lignin content by analytical pyrolysis, comparison with Klason and total lignin contents
No full textAnalytical pyrolysis can be used to determine the lignin content (Py-lignin) in eucalypt woods with a precision (0.37%) similar to the wet reference methods. Good correlations were found between the Py-lignin results and Klason (94%) and total lignin contents (95%). Besides apparent species-specific deviations, an average difference of 1.3% compared to the total lignin content was observed, well below the 3.9% difference reported for softwoods (guaiacyl lignin). Since Eucalyptus has more syringyl (S) than guaiacyl (G) units, this suggests that S units are overestimated in comparison to G units by analytical pyrolysis, in line with previous findings for different degradation methods, including pyrolysis.Instituto de BiotecnologíaFil: Alves, Ana. Universidade de Lisboa. Instituto Superior de Agronomia. Centro de Estudos Florestais; PortugalFil: Cisneros, Esteban F. Universidad Nacional de Santiago del Estero. Facultad de Ciencias Forestales. Instituto de Silvicultura y Manejo de Bosques; ArgentinaFil: Balmelli, Gustavo. Instituto Nacional de Investigación Agropecuaria (INIA). Estación Experimental del Norte. Programa Nacional de Investigación en producción Forestal; UruguayFil: Marcucci Poltri, Susana Noemi. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Marcucci Poltri, Susana Noemi. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rodrigues, Jose. Universidade de Lisboa. Instituto Superior de Agronomia. Centro de Estudos Florestais; Portuga
Noninvasive Detection of Clinically Significant Portal Hypertension in Compensated Advanced Chronic Liver Disease.
No full textPatients with compensated advanced chronic liver disease have different prognoses depending on the presence of portal hypertension. Current non-invasive diagnostic methods allow identification of clinically significant portal hypertension. Portosystemic collaterals on imaging or liver stiffness of more than 20 to 25 kPa by using transient elastography identifies patients with clinically significant portal hypertension. Patients with liver stiffness of less than 20 kPa and platelet count of greater than 150 g/L can avoid endoscopy. This rule could be expanded using spleen stiffness. Methods to risk stratify for portal hypertension in compensated advanced chronic liver disease and successfully treated chronic hepatitis C and B are subject of research
Current treatment options of refractory ascites in liver cirrhosis - A systematic review and meta-analysis.
No full textBACKGROUND
Refractory ascites is a severe complication of liver cirrhosis and treatment options consist in large volume paracentesis, transjugular intrahepatic portosystemic shunt, alfapump®, peritoneovenous shunt and permanent indwelling peritoneal catheter.
AIM
Our aim was to assess the efficacy, mortality and complications of each treatment.
METHODS
We performed a systematic review using Pubmed and Embase. Frequencies were summarized with Comprehensive Meta-Analysis Software.
RESULTS
Seventy-seven studies were included. In patients with transjugular intrahepatic portosystemic shunt, 1-year mortality was 33% (95% CI 0.29-0.39, I2=82.1; τ2 = 0.37; p<0.001) with lower mortality in newer studies (26% vs. 44%). At 6 months, mortality in patients with alfapump® was 24% (95% CI 0.16-0.33, I2=0.00; τ2 = 0.00; p = 0.83), 31% developed acute kidney injury (95% CI 0.18-0.48, I2=44.0; τ2 = 0.22; p = 0.15). Mortality at 12 months was 44% (95% CI 32%-58%, I2=76.7, τ2 = 0.44, p<0.001) in peritoneovenous shunts and 45% (95% CI 38%-53%, I2=61.4, τ2 = 0.18, p = 0.003) in large volume paracentesis, respectively. Overall mortality in patients with permanent indwelling catheters was 66% (95% CI 33%-89%, I2=82.5, τ2 = 1.57, p = 0.001).
DISCUSSION
Mortality in patients with transjugular intrahepatic portosystemic shunt was lower in newer studies, probably due to a better patient selection. Acute kidney injury was frequent in patients with alfapump®. Permanent indwelling catheters seemed to be a good option in a palliative setting
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