1,037 research outputs found
Lena Retamoso folio
No full textA folio of poetry by Lena Retamoso, appearing in the Spanish original and in English translation by the author, James Joseph Shay III, and Bruno Soria
Schizophrenia as a systemic disorder : studies of peripheral and central biological functions
No full textPsychiatric disturbances with an onset in adulthood may show subtle signs in childhood and school age. This is particularly applicable to patients with schizophrenia. A plasma membrane disturbance has been proposed as a common denominator responsible for both the central nervous system abnormalities and the changes in peripheral organs in patients with schizophrenia. The aim of the present thesis was to investigate central (neuropsychological, neurological and psychomotor) and peripheral (neuromuscular, tyrosine transport across the cell membrane) functions in schizophrenia with tyrosine kinetics as an indicator of membrane function. Another aim was to study possible familial transmission(s) of central and peripheral biological changes by investigating the occurrences of such abnormalities in unaffected first-degree relatives to the patients.Patients with schizophrenia (n = 39) their first degree- relatives (n = 44) and healthy controls (n = 55) were investigated according to the below listed studies.I. Clinical neurological investigation of neurological signs were performed. Psychomotor functions were investigated using the finger tapping, Purdue pegboard and pronation-supination tests, hand grasp strength, and gait.II. Histopathological examination of the skeletal muscle fibre was performed. The electrophysiological properties of the motor unit was studied in patients with schizophrenia and controls using the macro electromyographical (EMG) technique.III. Investigation of the muscle fibre histology and electrophysiology was performed as in study II in unaffected first-degree relatives to patients with schizophrenia.IV. Tyrosine transport (Km and Vmax) across the cell membrane was investigated in vitro using cultivated fibroblasts from patient with schizophrenia and healthy controls.V. Cognitive functions in patients with schizophrenia, their first-degree relatives and controls were assessed using an extensive battery of neuropsychological tests.Patients with schizophrenia exhibited neurological abnormalities and aberrant psychomotor performance to a significantly greater extent than healthy controls. Neuromuscular changes were found significantly more often in patients with schizophrenia and their unaffected first-degree relatives compared to controls. The most frequent histopathological finding in patients was muscle fibre atrophies, affecting both type I and type II fibres. Increased amplitude and area of the motor unit action potentials were found in the macro EMG recordings from patients and relatives but not in that from controls. The patients exhibited aberrant tyrosine transport kinetics with significantly lower Vmax (indicating lower tyrosine transport) and Km (indicating higher affinity) compared to controls. Finally, the patients performed significantly worse than their first-degree relatives and the controls in most of the neuropsychological tests and this significantly correlated with a lower level of functioning.Biological and clinical changes have been demonstrated deriving both from the central nervous system and peripheral organs indicating that schizophrenia is a systemic disease. Furthermore, the type of macro EMG findings and tyrosine transport aberrations indicate a membrane dysfunction. These results entail a different perspective on the ethiology of schizophrenia.List of scientific papersI. Flyckt L, Sydow O, Bjerkenstedt L, Edman G, Rydin E, Wiesel FA (1999). "Neurological signs and psychomotor performance in patients with schizophrenia, their relatives and healthy controls" Psychiatry Res 86(2): 113-29 https://pubmed.ncbi.nlm.nih.gov/10397414II. Flyckt L, Borg J, Borg K, Ansved T, Edman G, Bjerkenstedt L, Wiesel FA (2000). "Muscle biopsy, macro EMG, and clinical characteristics in patients with schizophrenia" Biol Psychiatry 47(11): 991-9 https://pubmed.ncbi.nlm.nih.gov/10838067III. Flyckt L, Wiesel FA, Borg J, Edman G, Ansved T, Sydow O, Borg K (2000). "Neuromuscular and psychomotor abnormalities in patients with schizophrenia and their first-degree relatives" J Psychiatr Res 34(4-5): 355-64 https://pubmed.ncbi.nlm.nih.gov/11104850IV. Flyckt L, Venizelos N, Edman G, Bjerkenstedt L, Hagenfeldt L, Wiesel FA (2000). "Aberrant tyrosine transport across the cell membrane in patients with schizophrenia." (Submitted)V. Eriksson A, Nyman H, Flyckt L, Edman G, Bjerkenstedt L, Wiesel FA (2000). "Neuropsychological function in patients with schiziphrenia, their relatives, and normals." (Submitted)</p
Interpretation and performance of three orchestral compositions by Gabriela Lena Frank: Escaramuza, Elegia Andian, and Three Latin American Dances
No full textThis work presents interpretative and performance suggestions for three of Gabriela Lena Frank’s orchestral works: Escaramuza (2010), Elegia Andina (2000), and Three Latin American Dances (2004). Frank’s compositions frequently include programmatic elements that reference other well-known compositions, and she incorporates melodies, rhythms, timbres, instrumentation, and performance techniques characteristic of her Peruvian cultural heritage. Examples of these elements are presented from a lecture recital format to demonstrate how performance practice and conducting decisions—in rehearsal and performance—can be utilized to honor the composer’s expressed intent and overcome various technical ensemble and conducting challenges. An overview of the cultural contextual elements includes Harawi and Kachampa dance structures. The author also suggests methods for presenting elements that affect the timbre and instrumental scoring specific to each work, for example the Andean Zampoña. This research provides performers with a resource to deepen their score study, and seeks to inspire more people to perform the music of Gabriela Lena Frank.D. A
Enzyme-catalyzed polyester synthesis
No full textAuthor Lena Graf BScMasterarbeit Universität Linz 202
Enzyme-catalyzed polyester synthesis
No full textAuthor Lena Graf BScMasterarbeit Universität Linz 202
Cladal Divergence in Fungal Ophiognomonia (Gnomoniaceae, Diaporthales) Shows Evidence of Climatic Niche Vicariance
No full textWe used the globally widespread genus Ophiognomonia as a model system to investigate climatic niche patterns in fungi, characterizing the climatic profiles of 28 species with seven temperature and seven precipitation variables. Using a novel version of Spatial Evolutionary and Ecological Vicariance Analysis (SEEVA), designed to deal with continuous and correlated variables, we examined well-sampled phyletic splits of a multi-gene phylogeny. We evaluated the degree to which phyletic divergence has been associated with climatic niche divergence between sister lineages, permitting elucidation of climatic associations in evolutionary context. From the 14 inter-correlated climatic variables, we extracted four principal axes, accounting for 93.2% of the climatic variation, with axes broadly labeled as: polarity, tropicality, winter mildness, and aridity. We also analyzed the two single variables maximum monthly temperature and precipitation. We detected climatic associations that were compatible with both niche-conservatism and niche-divergence within the phylogeny, and different cladistic bifurcations associated with different climatic splits. As might have been anticipated, geographic separation (or lack thereof) of phylogenetic splits was correlated with climate niche divergence (or conservation). This elaborated SEEVA method provides a visual and statistically solid basis for characterizing climatic niche divergence that should prove useful for elucidation of many other taxonomic groups.Peer reviewe
Lena Rivers Dinner and a Movie
No full textInvitation to Friends of Drake Library sponsored event - "The Sin of Lena Rivers" Dinner and a Movie, Based on book by Brockport author, Mary Jane Holmes.Archived web contentSUNY BrockportFODL Ephemer
Lena Rivers Dinner and a Movie
No full textInvitation to Friends of Drake Library sponsored event - The Sin of Lena Rivers Dinner and a Movie, Based on book by Brockport author, Mary Jane Holmes.https://digitalcommons.brockport.edu/fodl_ephemera/1000/thumbnail.jp
Le stanze della memoria di Lena Constante
No full textMuovendo dai volumi di memorie The silent escape e The impossible escape di Lena Constante, il contributo cercherà di dimostrare come il luogo dell’evasione silenziosa sia uno spazio altro, eterotopico, nei termini proposti da M. Foucault. In particolare, si mostrerà come la costruzione di questo spazio si fondi su due condizioni esterne imprescindibili: la solitudine e il silenzio.Starting from Lena Constante’s memoirs The silent escape and The impossible escape, this contribution will try to discuss how the space of a “silent breakout” is an other, heterotopic space as in M. Foucault’s propositions. The Author will explain in particular how the construction of such a space is conditioned by two essential factors: solitude and silence
- …
