378 research outputs found
[Ultrasound-guided paracentesis: technical, diagnostic and therapeutic aspects for the modern nefrologist]
Ascites is a pathological accumulation of fluid in the peritoneal cavity due to various etiologies, often associated with renal failure. Paracentesis is a simple method of removing ascitic fluid by inserting a needle into the peritoneal cavity, often performed at the patient's bedside. It can be both diagnostic and therapeutic. Ultrasound imaging allows the diagnosis of ascites, the identification of the puncture site on the abdominal wall during the pre-procedural phase, the real time evaluation of the needle and the continuous course of the maneuver. This eco-guide technique has higher effectiveness and lower risk of complications than the "blind" venipuncture technique. Ultrasound-guided paracentesis, when performed by nephrologists, reduces the waiting time both for the execution of paracentesis and for the diagnosis, treatment and follow-up of ascites
[Talking about medicine through mass media]
: The ability to communicate is central to all professional activities and therefore being able to communicate effectively with mass media is essential. The medical doctor often needs to communicate not with a single patient or with a group of family members, but with "an important number of patients" through a microphone, a newspaper, a radio or a television. In this case it is not necessary to provide specific information on a single clinical case, but to provide simple, general information on a single pathology or a group of diseases to an interviewer or journalist, who will probably elaborate it at his own discretion making it usable to a diverse and unspecified audience. It is therefore important to be relevant to the question, clear in the presentation, but also synthetic to respect the time limits of interview
Un ricordo personale di Fulvio Papi
The article reflects on Fulvio Papi’s philosophical approach, highlighting his dedication to simplifying complex ideas to reveal underlying truths. The author recounts personal interactions that demonstrate Papi’s ability to engage deeply yet succinctly with philosophical concepts, enhancing understanding and discussion. The article underscores Papi’s impact through his commitment to clarity and ethical simplicity, leaving a lasting legacy in philosophical discourse
[Management of color-Doppler imaging in dialysis patients]
: In recent decades, the survival of dialysis patients has gradually increased thanks to the evolution of dialysis techniques and the availability of new drug therapies. These elements have led to an increased incidence of a series of dialysis-related diseases that might compromise the role of dialysis rehabilitation: vascular disease, skeletal muscle disease, infectious disease, cystic kidney disease and cancer. The nephrologist is therefore in charge of a patient group with complex characteristics including the presence of indwelling vascular and/or peritoneal catheters, conditions secondary to chronic renal failure (hyperparathyroidism, anemia, amyloid disease, etc.) and superimposed disorders due to old age (cardiac and respiratory failure, cancer, type 2 diabetes mellitus, etc.). Early clinical and organizational management of such patients is essential in a modern and ''economic'' vision of nephrology. The direct provision of ultrasound services by the nephrologist responds to these requirements. A minimum level of expertise in diagnostic ultrasonography of the urinary tract and dialysis access should be part of the nephrologist's cultural heritage, acquired through theoretical and practical training programs validated by scientific societies, especially for those who choose to specialize in these procedures and become experts in imaging or interventional ultrasonography
Il futuro delle tecniche ultrasonografiche in nefrologia
Thanks to the wide geographical diffusion, low cost and lack of ionizing radiation, ultrasound is now the most widely used imaging technique in clinical practice, second only to chest radiography. Recent technological innovations and introduction of ultrasound contrast agents, further expanded the fields of application of ultrasound, guarantying for the future to this technique an important role in imaging of the urinary tract. The nephrologist must be able to exploit the potential offered by technological innovations in ultrasound imaging for the study of the kidney. The proper management of equipment, in fact, allows to obtain ultrasound images in gray scale of the highest quality, to optimize the diagnostic accuracy of Doppler techniques and take full advantage of the tools offered by means of ultrasound contrast agents
Fair and Equitable Treatment and the Fabric of General Principles
This book moves from the circumstance whereby currently the obligation to provide fair and equitable treatment (FET) to foreign investments is included in the majority of international investment agreements and has proved to be the most invoked standard in investor-State arbitration. Hence, it is no overstatement to describe this standard as the basic norm of international investment law. Yet both its meaning and normative basis continue to be shrouded in ambiguity and, as a consequence, to inspire a considerable number of interpretations by legal writers. The book's precise aim is to unravel such ambiguity, arguing from the idea that FET has become part of the fabric of general international law, but has done so by means of a source somewhat neglected in legal doctrine. This being the category of general principles peculiar to a certain field of international law, i.e. those principles having their own foundations in the international legal order itself, but which, through the mediation of the judge, end up being shaped according to the features typical of a specific normative field. The book, as well as having a solid theoretical backdrop as its basis, offers a careful and critical analysis of pertinent case law, and will prove useful to both scholars and practitioners. Fulvio Maria Palombino is Professor of International Law at the Law Department of the University of Naples Federico II and a member of the Executive Board of the European Society of International Law. Specific to this book: • Explains the ICSID practice clearly and concisely • Useful in practical terms Excerpts from a review: 'Fair and Equitable Treatment and the Fabric of General Principles' is an original and well researched book, in which the author challenges a number of conventional wisdoms on FET.Among the strengths of the book one can mention the solid discussion of public international law principles relevant to FET and the interesting incursions into domestic law legal systems which play an important role in the understanding of FET components such as due process, legitimate expectations or proportionality. In particular the section on promises provides a convincing analysis of the issues that arise when the administration makes an assurance or representation to an investor. Against the backdrop of the examination of unilateral acts under public international law, Palombino's analysis sheds new light on what ought to be the proper scope of protection under the legitimate expectations doctrine in case of governmental promises, clarifying a number of points which have received insufficient attention by arbitral tribunals thus far. - Michele Potestà, Attorney with Lévy Kaufmann-Kohler, Geneva; Senior Researcher, Geneva Center for International Dispute Settlement (CIDS) book review in International and Comparative Law Quarterly, (2018)67(4), 1036-1037. For the full review, see: https://doi.org/10.1017/S0020589318000246
Does Renal Denervation a Reasonable Treatment Option in Hemodialysis-Dependent Patient with Resistant Hypertension? A Narrative Review
Purpose of Review This narrative review aims to assess the pathophysiology, diagnosis, and treatment of resistant hypertension (RH) in end-stage kidney disease (ESKD) patients on dialysis, with a specific focus on the effect of renal denervation (RDN) on short-term and long-term blood pressure (BP) control. Additionally, we share our experience with the use of RDN in an amyloidotic patient undergoing hemodialysis with RH.Recent Findings High BP, an important modifiable cardiovascular risk factor, is often observed in patients in ESKD, despite the administration of multiple antihypertensive medications. However, in clinical practice, it remains challenging to identify RH patients on dialysis treatment because of the absence of specific definition for RH in this context. Moreover, the use of invasive approaches, such as RDN, to treat RH is limited by the exclusion of patients with reduced renal function (eGFR < 45 mL/min/1.73 m3) in the clinical trials. Nevertheless, recent studies have reported encouraging results regarding the effectiveness of RDN in stage 3 and 4 chronic kidney disease (CKD) and ESKD patients on dialysis, with reductions in BP of nearly up to 10 mmhg.Summary Although multiple underlying pathophysiological mechanisms contribute to RH, the overactivation of the sympathetic nervous system in ESKD patients on dialysis plays a crucial role. The diagnosis of RH requires both confirmation of adherence to antihypertensive therapy and the presence of uncontrolled BP values by ambulatory BP monitoring or home BP monitoring. Treatment involves a combination of nonpharmacological approaches (such as dry weight reduction, sodium restriction, dialysate sodium concentration reduction, and exercise) and pharmacological treatments. A promising approach for managing of RH is based on catheter-based RDN, through radiofrequency, ultrasound, or alcohol infusion, directly targeting on sympathetic overactivity
The Four Engravings : between word and image
This essay is part of a volume which offers the first comprehensive study of the De Nola (Venice 1514), a hitherto underappreciated Latin text written by the Nolan humanist and physician Ambrogio Leone. Divided into three books and enriched by four engravings, De Nola is an extraordinary historical, chorographical and topographical treatise celebrating the city of Nola in the Kingdom of Naples. Its author was the Nolan physician and humanist Ambrogio Leone, who dedicated the work to Enrico Orsini count of Nola, while its publisher was Joannes Rubeus, or Giovanni Rosso from Vercelli. The volume would mark an important advance in European humanistic and antiquarian debates. Leone’s description of a seemingly minor urban centre in the peninsula is an innovative and ground-breaking work of Renaissance scholarship. Several decades after Biondo Flavio’s studies of Rome and Italy had appeared in print, De Nola marked a shift in antiquarian publications, and opened the way to a new approach to the description of cities. Its fame was enduring, reaching beyond the borders of the Italian peninsula to the main centres of Renaissance European culture. Despite its profound originality and its early and widespread circulation, De Nola has remained at the margins of Renaissance studies.
The chapter written by Fulvio Lenzo discusses the four engravings, which help to make Leone’s book an early sixteenth century masterpiece of humanist literature. His analysis of the engravings clarifies the important role played by Leone himself in planning and drawing the illustrations, and reduces the role of the Venetian painter and engraver Girolamo Mocetto to little more than an executor of Leone’s ideas.
Leone relied, at a first level, on a massive use of written sources relating to a wide range of disciplines. He appears as a reader (and certainly also an owner) of manuscripts and above all of printed editions, like those published by his friend Aldo and composed in Greek characters with the support of Grifo’s renewed Greek typeset; but also as a tireless ‘devourer’ of mathematical and geometrical treatises, like Luca Pacioli’s edition of Euclid. He certainly consulted (or even possibly possessed) illustrated books like the famous Hypnerotomachia Poliphili, or the 1511 edition of Ptolemy’s geographical work (edited by another émigré from the Kingdom of Naples, namely Bernardo Silvano of Eboli), or architectural treatises like Fra Giocondo’s edition of Vitruvius, all printing products which displayed an impressive iconic apparatus; but he also studied a deliberately aniconic book as Leon Battista Alberti’s De re aedificatoria, a real bestseller at the time, where mental images were created by the power of words. Ambrogio Leone considered his book not only a medium for the publication of his text, but also a valuable art object, in which renewed illustrations play a relevant role
"Presentación del libro de José M. Sevilla Prolegómenos para una crítica de la ra zón problemática. Motivos en Vico y Ortega"
Presentación leída en español por el autor, en la Universidad de Sevilla el día 6 de junio de 2011, en el acto de presentación conjunta de los libros Prolegómenos para una crítica de la razón problemática. Motivos en Vico y Ortega (José M. Sevilla) y Filosofía de la razón plural. Isaiah Berlin entre dos siglos (Pablo Badillo O’Farrell, Coord.); acto en el que participaron los profesores Joaquín Abellán, Pablo Badillo, Giuseppe Cacciatore, José M. Sevilla y Fulvio Tessitore.Introduction read in Spanish by the author, in the joint launching of the books Prolegómenos para una crítica de la razón problemática. Motivos en Vico y Ortega (José M. Sevilla) and Filosofía de la razón plural. Isaiah Berlin entre dos siglos (Pablo Badillo O’Farrell, Coord.) that took place at the University of Seville on June the 6th, 2011. The act counted with the participation of Joaquín Abellán, Pablo Badillo, Giuseppe Cacciatore, José M. Sevilla and Fulvio Tessitore
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