323,260 research outputs found
Sustainability in the food sector: a bibliometric and network analysis of the literature
No full textThe issue of sustainability in the food sector is gaining increasing interest. Although this issue is of considerable interest to researchers and practitioners, to our knowledge there is not yet a literature review which illustrates the areas of greatest interest. The aim of this paper is to explore the status of sustainability research in the food sector, identifying the most discussed research fronts. The methodology adopted to carry out this literature review is network analysis through bibliometric tools, which are very effective in identifying current and new issues of interest. Starting from a sample of 601 articles, through the use of bibliometric tools four major clusters of research are identified: food waste management, environmental impact, models for sustainable supply chain design and consumers' behaviour towards food sustainability. These results can help researchers and practitioners to understand trendsetting topics, to detect potential research gaps and to outline future research avenues
A review of the literature on innovation in the agrofood industry: sustainability, smartness and health
No full textPurpose: Following the Agenda 2030 for Sustainable Development, the main challenge for the agrofood sector is to innovate food production, offering sustainable, smart and safe solutions. The future of food production will be oriented more and more towards sustainable industries with high technological content to guarantee food safety and food security. It implies that a change not only in the way food is conceived, but also in the way it is produced, processed and consumed is needed. The aim of the present study is to investigate the role of innovation, sustainability, smartness and health within the agrofood industry. Design/methodology/approach: A literature review was conducted using 596 academic documents written in English language and published in peer-reviewed scientific journals as well as in conference proceedings. The relevant articles were analyzed using both a bibliometric and a systematic approach. Findings: The results confirm the role of innovation and sustainability as key drivers in the food industry. The main findings concern the benefits deriving from the adoption of digital technologies, the ever-increasing involvement of consumers in health and environmental issues and the introduction of the open innovation concept in the agrofood industry. Originality/value: This study jointly considers the dimensions of innovation, sustainability, smartness and health in the agrofood sector, demonstrating how they are strongly interdependent
Cardiotoxicity of doxorubicin: effects of drugs inhibiting the release of vasoactive substances
No full textInvestigating circular business model innovation through keywords analysis
No full textOngoing economic, social and environmental developments have forced the production system to undertake a profound transformation, shifting from a linear to a circular model. The transformation towards a circular economy poses significant challenges for established companies, in many cases requiring a strong modification of their current business models, start-ups and new ventures. Firms need to completely rethink their value proposition, modifying how the product or service is produced, delivered to the customers and disposed of. As a result, interest in business model innovation with a view to a circular system has increased significantly over the last five years, leading to a flourishing literature production. Although several literature reviews have been published on the topic of the circular business model, few of them include the innovation dimension. Moreover, the time horizon covered by the previous reviews extends to 2019 and in one case to 2020. Since 2020 saw a 135% increase in scientific production compared to the previous year, it is necessary to update the prior works, taking into account the new contributions. Our paper aims to bridge this gap by proposing a literature review based on keywords analysis. In this way, it is possible to analyze the issues addressed in the circular business model innovation (CMBI) by categorizing them as core, emerging/phantom, trendy or intermittent. This analysis is particularly suitable for identifying future research directions as signaled by the emerging themes
Cardiovascular effects of 15(S) 15 methyl-PGF2 alpha.
No full textThe effects of 15(S) 15-methyl-PGF2 alpha were studied on the cardiovascular system of dogs. Intravenous and intravertebral artery administration of 15(S)-methyl-PGF 2 alpha induced arterial hypertensive and respiratory effects more intense and longer lasting than those observed for PGF2 alpha. Intravenous administration of 15(S) 15-methyl-PGF2 alpha induced a decrease of vascular reactivity to 1-norepinephrine and 1-epinephrine and to carotidal occlusion. Infiltration of the carotid sinus walls with 15(S) 15-methyl-PGF2 alpha decreased the baroreceptor reactivity
Sustainability and Open Innovation: Main Themes and Research Trajectories
No full textToday, innovation and sustainability in their broadest sense, which includes people (social dimension), the planet (environmental dimension) and profits (economic dimension), are increasingly intertwined. Integrating the sustainability dimension into the innovation of products, services, processes, technologies, business and organizational models requires an effort on the part of the company as it demands a different set of knowledge and skills than those needed to innovate in a traditional way. As a result, companies, in order to integrate the dimension of sustainability in their innovation processes, have felt the need to exploit knowledge, skills and technologies external to the organization itself, promoting what is called the process of open innovation. Since this field of field is only recently being explored, we conducted a literature review through bibliometric analysis on a sample of 93 scientific articles published between 2011 and today, April 2022. To achieve the purpose of this review, both quantitative (co-occurrence analysis) and qualitative analysis have been conducted. Four different research themes have been identified: sustainable open innovation and innovation performance, the role of technological capability for sustainable open innovation, business model perspective and sustainable open innovation and university collaboration. As far as future research is concerned, a mainline has been identified concerning the study of sustainable open innovation in the agri-food industry
Cardiotoxicity of doxorubicin: effects of drugs inhibiting the release of vasoactive substances.
No full textThe therapeutic usefulness of doxorubicin, an antineoplastic drug, is limited by its cardiotoxicity whose mechanism is as yet unknown. Several hypotheses have been postulated including also the release of vasoactive substances, so the aim of the present investigations was to study the relationship between the release of vasoactive substances and the development of doxorubicin-induced cardiotoxicity. The effects of the following drugs on doxorubicin-induced (cumulative dose of 20 mg/kg intraperitoneally) cardiotoxicity in rats have been evaluated: verapamil (1 and 10 mg/kg orally), that inhibits the slow channel influx of calcium and catecholamine release, acetylsalicylic acid (50 and 100 mg/kg orally), that inhibits the prostaglandin biosynthesis and release, and cromolyn sodium (cromolyn; 1 and 10 mg/kg orally), that inhibits the secretion of histamine. Our results showed that verapamil reduced and delayed doxorubicin-induced mortality, and limited doxorubicin-induced body weight decrease and ECG changes. Acetylsalicylic acid and cromolyn did not protect against doxorubicin-induced cardiotoxicity. These findings suggest that the release of vasoactive substances does not play a prevalent role in the development of doxorubicin-induced cardiotoxicity. The protective effect of verapamil is probably due to the inhibition of doxorubicin-induced intracellular calcium overload
Open innovation and incorporation between academia and the food industry
No full textThe food industry is increasingly choosing to enhance internal idea development by pursuing an open approach to innovation, exploiting external knowledge and market paths. This chapter provides an overview on “Open Innovation” as implemented in the food industry. Specifically, based on a range of essential case studies, a comprehensive overview of the adoption of the Open Innovation paradigm in the food industry is provided. Then, the role of academia in such a context is investigated, and a “4W Open Innovation model” for the academia-industry interaction, including motives, facilitators and hindering factors (Why/why not), type of exchanged knowledge (What), practices and activities (hoW), and actors (With whom), is proposed. The main results reveal the main challenges and paradigm shifts of the food industry and identify implications for the future of Open Innovation in the sector
Factors affecting the growth of academic oriented spin-offs
No full textAcademic spin-offs are companies created by one or more members of a research laboratory with the purpose of commercializing the obtained results or the technologies produced within the university. During the last two decades, academic spin-offs have received increasing attention from both researchers and practitioners, however there are few studies in the literature regarding the factors that foster its growth (Ferretti et al., 2020). Based on these premises, this chapter aims to investigate more thoroughly the growth phase of an academic spin-off’s life-cycle, focusing in particular on the drivers that influence its growth. Moreover, a focus on the academic spin-off phenomenon in the food sector is provided. The methodology adopted is that of literature review, combining two different approaches: the bibliometric analysis and the keywords analysis
Innovation Models in Food Industry: A Review of The Literature: Innovation models in food industry
No full textInnovation is considered as one of the main elements of a company success. In recent years, it has assumed a relevant role also in the food industry that was generally defined as a rather mature and slow-going sector. The aim of this paper is to analyse the innovation models applied to the food industry and to carry out a systematic review of the literature. In particular, we overview the most relevant innovation models and identify the main thematic areas discussed in the period from 2016 to 2020. We also provide recommendations for future research directions
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