2,314 research outputs found
Gabriele Ferri
No full textGabriele Ferri is an Assistant Professor at Eindhoven University of Technology (TU/e). His work explores the intersection of Design Justice and Transforming Practices, focusing on the intended and unintended consequences of design. With an emphasis on bottom-up processes, the right to repair, and climate justice, Gabriele collaborates with communities to challenge systemic injustice and co-create equitable alternatives. Frustrated by the unsustainable cycle of production, consumption, and disposal, he advocates for practices that prioritize care, repair, and extending the “long life” of design artifacts
In memoriam. Per Corrado Ferri (1940-2024)
No full textGabriele Scaramuzza reflects on the philosophical and intellectual legacy of Corrado Ferri, highlighting their rich dialogues on historical, musical, and existential themes. The article, written in memoriam following Ferri’s death in 2024, intertwines personal anecdotes with scholarly dialogue, illustrating Ferri’s dynamic personality and diverse interests. This tribute emphasizes Ferri’s approach to life and learning, characterized by his curiosity and critical engagement with diverse cultural and philosophical issues. Scaramuzza portrays Ferri as a thinker who seamlessly integrated personal experiences into his scholarly pursuits, making significant contributions to philosophical discourse and mentoring
First-Person Speculative Fabulation:A Workshop Method for Times of Crisis
No full textInte Gloerich and Gabriele Ferri investigate the impacts of Covid-related datafication on marginalized urban communities, emphasizing the importance of creativity and imagination in fostering resilience and agency in the face of ongoing and future crises
First-Person Speculative Fabulation:A Workshop Method for Times of Crisis
No full textInte Gloerich and Gabriele Ferri investigate the impacts of Covid-related datafication on marginalized urban communities, emphasizing the importance of creativity and imagination in fostering resilience and agency in the face of ongoing and future crises
Dall’epifania mancata alla macchina del supplizio. Su alcune figure nei film di Luca Ferri
Full text linkNe "L'uomo comune del cinema" di Jean Louis Schefer troviamo una suggestiva evocazione del cinema in un'immagine di "Vampyr": «Nel film di Dreyer vediamo la ruota del mulino, la farina, il vampiro costretto contro un muro [...] Qui, gli ingranaggi e le pulegge sono un apparecchio del tempo, e i loro movimenti producono la scomparsa di un corpo nella polvere». Il trascinamento della pellicola come conditio sine qua non dell'immagine in movimento (e quindi dello spettacolo cinematografico), ma anche come radice stessa della sua cancellazione. Questo legare insieme meraviglia e orrore, spettacolo e morte, pone l'apparecchio cinematografico nella stessa famiglia di marchingegni che Michel Carrouges, sulla scorta di Duchamp, ha battezzato “macchine celibi”. Si può parlare quindi del cinematografo come corrispettivo reale delle macchine immaginarie di Jarry e Roussel? Esiste davvero nel cinema una vocazione “celibe”?
Il presente saggio intende evidenziare come nell'attuale panorama del cinema italiano esista almeno un regista, Luca Ferri (Bergamo, 1976), la cui opera – e in particolare il lungometraggio "Ecce Ubu" (2012), qui preso in esame – può considerarsi una vera e propria attuazione del cinematografo come macchina celibe. Ferri sembra usare il dispositivo cinematografico in modo analogo alla macchina del supplizio di Kafka: scarnifica il corpo del film sino all'osso (il semplice, ripetitivo, ossessivo movimento delle immagini), e insieme ne registra impietosamente il collasso sotto lo sguardo annichilito degli spettatori/vittime. Lontano da ogni feticismo della pellicola, così come da qualsiasi intento archeologico, il cinema di Ferri, nella sua essenzialità antica, quasi “lumièriana”, ci pone di fronte al destino ultimo delle immagini in movimento: la loro distruzione.In Jean Louis Schefer's "The Ordinary Man of Cinema" we find a suggestive evocation of cinema in an image of "Vampyr": "In Dreyer's film we see the wheel of the mill, the flour, the vampire forced against a wall [...] Here, the gears and the pulleys are a device of time, and their movements produce the disappearance of a body in the dust". The dragging of the film as a sine qua non of the moving image (and therefore of the film show), but also as the very root of its cancellation. This combination of wonder and horror, spectacle and death, places the film equipment in the same family of devices that Michel Carrouges, in the company of Duchamp, called " bachelor machines ". Can we speak of the cinema as the real equivalent of the imaginary machines of Jarry and Roussel? Is there really a "celibate" vocation in cinema?
This essay aims to highlight how in the current panorama of Italian cinema there is at least one director, Luca Ferri (Bergamo, 1976), whose work - and in particular the feature film "Ecce Ubu" (2012), examined here - can be considered a real implementation of the cinema as a bachelor machine. Ferri seems to use the cinematographic device in an analogous way to Kafka's torture machine: he stripped the body of the film down to the bone (the simple, repetitive, obsessive movement of the images), and at the same time ruthlessly recorded its collapse under the annihilated gaze of the spectators/victims. Far from any fetishism of the film, as well as any archaeological intent, Ferri's cinema, in its ancient essentiality, puts us in front of the ultimate destiny of the moving images: their destruction
Interactive Digital Narrative – What’s the Story? [Hartmut Koenitz / Gabriele Ferri / Mads Haahr / Digdem Sezen / Tonguc Ibrahim Sezen (Eds.): Interactive Digital Narrative: History, Theory and Practice. New York 2015]
No full textRezension zu / Review of: Hartmut Koenitz / Gabriele Ferri / Mads Haahr / Digdem Sezen / Tonguc Ibrahim Sezen (Eds.): Interactive Digital Narrative: History, Theory and Practice. New York 2015</p
New rosmaricine derivates as anticancer agents
No full textRosmaricine (Fig.1) is a diterpenoid aminocompound obtained from dried leaves of Rosmarinus officinalis L. treated with ammonia in the presence of air. It is an alkaloidal artifact formed through a complex reaction between some oxidation derivatives of carnosic acid and the ammonia used to liberate the bases supposed to be present in the ethanolic extract.1,2
Rosmaricine is structurally similar to the natural diterpenes carnosol and rosmanol, both endowed with antioxidant, radical scavenger and antiproliferative activities through a mechanism that involve, among others, NF-kB and STAT-3 inhibition.3
In view of the growing interest on terpenoid compounds as potential antitumoral drugs and following our recent studies on sulphurated drug-hybrids as multitarget anticancer agents,4,5 we synthesized three new derivatives through the condensation of the amino group of rosmaricine with some sulfurated carboxylic acids, containing a thiosulfonate or allyldisulfide or a dithiolethione moiety (Fig. 1) and investigated their ability to inhibit STAT-3 and NF-kB transcription factors as well as their antiproliferative activity on a human cancer cell line.
Results showed that rosmaricin and its derivatives inhibited HCT-116 cell proliferation in vitro with IC50 in micromolar range. In addition, they were able to strongly and selectively bind STAT-3 SH2 domain in an Alpha Screen assay and were also able to inhibit the NF-kB transcriptional activity in HCT-116 cell line.
The obtained data underline the interesting profile of these compounds which are worthy of further investigation as potential multitarget anticancer agents.
References
1. E. Wenkert, A. Fuchs, J.D. McChesney J.Org. Chem. 1965, 30, 2931-2934.
2. A. Boido, F. Savelli, F. Sparatore Il Farmaco 1994, 49, 111-114.
3. C. Lai, J. H. Lee, C. Ho, C. B. Liu, J. Wang, J. Wang, M. Pan J. Agric. Food Chem. 2009, 57, 10990-10998.
4. Gabriele E.; Barteselli A.; Moiana V.; Porta F.; Gelain A.; Asai A.; Sparatore A. Methanethiosulfonate derivatives as ligands of STAT3-SH2 domain. “Tefarco NFPC8” (Parma, Italy, 9-11 June 2014); Poster communication P-18.
5. Gabriele E.; Brambilla D.; Ferri N.; Asai A.; Sparatore A. New sulfurated cinnamic acid derivative as multitarget anticancer agents. Book of Abstract – SIMCC2015 - Spanish-Italian Medicinal Chemistry Congress (Barcellona, Spain - July 12-15, 2015) - P-90
About twin primes and distribution of primes
Full text linkThis paper give us a demonstration of twin primes conjecture using approximation of function �(iupsilon) that we introduce in section 6. Section 1-5 give us introduction to terminology and a clarification on (iupsilon) terms. In particular section
5 is really important because of its Lemma. Section 7 reassume foregoing explanations and it give us two theorems and one corollary;the theorem 7.2 give us exact approximation of twin primes counting function
Corpi sportivi e pratiche di ben-essere: il caso degli Urban Game a Bologna
No full textLa progressiva affermazione del corpo sportivo è indicatore oggi di una cultura diffusa volta a trasformare la pratica sportiva in un progetto più ampio. Alla base vi è l’idea che le pratiche motorie- sportive siano uno strumento privilegiato per raggiungere il ben-essere (well-being), inteso come saperi e azioni orientate alle buone pratiche (well-doing), coinvolgendo in egual misura individuo, collettività e ambiente. In questa cornice il presente contributo presenta l’analisi di un case study italiano - “Pie’ Veloci”, gioco urbano realizzato nel 2011 a Bologna – con l’utilizzo di una metodologia integrata (lettura etnografica e comunicativa), allo scopo di illustrare come pratiche ludico sportive possono dare luogo a comportamenti virtuosi all’interno di una comunità. Gli Urban game si rivelano infatti utili strumenti alla socializzazione ed al coinvolgimento dei partecipanti finalizzati all’esplorazione ed alla ri-appropriazione dello spazio urbano secondo logiche di best practices.Today, the progressive affirmation of the sporting body refers to a widespread culture transforming sport into a wider project. Its starting point is that sports and physical activity are privileged instruments to achieve well-being, understood as competences and action-oriented best practices (well-doing) involving in equal measure single subjects, communities and the environment. Within this framework, this paper analyze a recent Italian event - "Pie' Veloci", a urban game performed in Bologna in 2011 - through an integrated methodology between Ethnography and Communication Studies, arguing that ludic and sporting practices may lead to virtuous behaviors in communities. Indeed, urban games emerge as useful tools to promote socialization and engagement through the exploration and re-appropriation of urban spaces following the logic of best practices
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