1,720,985 research outputs found
HUBUNGAN PROCALSITONIN DAN GAMBARAN MORFOLOGI LEUKOSIT PADA INFEKSI BAKTERIAL
Get PDFAbstract: Bacterial sepsis increases morbidity and mortality in all ages. Early detection has been shown to be crucial for the improved outcome of patients with sepsis. Till now there is no routine test for
screening. Procalcitonin and morphology of leukocytes are biomarkers of bacterial sepsis. The aim of this study was to determine the relationship between procalcitonin and morphology of leukocytes as marker in bacterial infection. This study was analytical observational with cross sectional design and data collected prospectively.This study measured simultaneously the value of procalcitonin and morphology of leukocytes examination in patients with suspected bacterial infection in hospital X of Yogyakarta. Data were analysed by statistics. The results showed immature granulocytes and vacuolization of neutrophils in the leucocytes morphology has a significant correlation with level of procalcitonin.
Keywords: bacterial infection, procalcitonin, morphology of leukocyte
ASSOCIATION BETWEEN SMOKING BEHAVIOUR AND GLYCOHEMOGLOBINE LEVELS AMONG ADULT JAVANESE INDONESIAN SMOKERS
Get PDFNicotine, the active compound in cigarettes, can cause impaired glucose metabolism byincreasing insulin resistance as well as decreasing insulin secretion in ? cell pancreas. Thiscondition can increase the risk of type 2 diabetes in human. This study aims to evaluate the effectof smoking behaviour, determined by Cigarette per Day (CPD) and smoking duration, onglychohemoglobine (HbA1c) levels of Javanese Indonesian smokers. 30 smokers were studiedconsisting of 7 smokers with 10 CPD, 19 smokers with 11-20 CPD and 4 smokers with 21-30CPD. They had been smoking for more than 10 years. The whole blood sample was used toexamine the HbA1c levels. The HbA1c levels were tested at Bethesda Hospital's cliniclaboratories using Architect 600 instrument. The results showed that CPD and smoking durationsignificantly influenced HbA1c, in which F count was F table (370.541 3.354) withsignificance 0.05 (2.35. 10-20 0.05) and multiple correlation coefficient (R) of 0.982.Therefore, based on this research finding, it was concluded that longer smoking duration andhigher CPD caused higher smokers HbA1c level
POLA KUMAN DAN SENSITIVITAS ANTIMIKROBA PADA INFEKSI SALURAN KEMIH
Get PDFAbstract: A urinary tract infections (UTI) is an infection that affects the urinary tract caused by bacteria (most often Escherichia coli). Antimicrobial are used to treat UTI. The sensitivity of bacterial pattern toward antimicrobials and the bacterials pattern will affect the effectiveness of UTI treatment. This research was conducted to evaluate the strains of bacterial and sensitivity of bacterial pattern that caused UTI. A descriptive evaluation and retrospective study was done in this research. In total 79 cases patient with UTI at Inpatient Unit “X” hospital in Yogyakarta 2011, whose has sensitivity test and sprout up germ culture examination data were included. Patient with UTI at Inpatient Unit which has barren germ culture data and sprout up germ were excluded. The common microbes were gram negative bacteria including Escherichia col, Pseudomonas aeruginosa, Klebsiella pneumonia, and Staphylococcus coagulase negative. Gram negative microbes were sensitive to amikasin, imipenem, netilmicin, and fosfomicin. Gram positive microbes were sensitive to nitrofurantoin, vancomicin, imipenem and cefuroxime.
Keywords: Urinary Tract Infection, antimicrobial, and sensitivity bacterial pattern
Studi Genotipe Sitokrom P450 2A6 Alel CYP2A6*4 dan CYP2A6*9 pada Subyek Uji Perokok Suku Jawa Indonesia
Get PDFCYP2A6 belongs to the CYP2 family of P450 cytochromes were highly polimorphy. CYP2A6*1 (wild type) was an active allele, CYP2A6*9 was agen decreased allele and the CYP2A6*4 was an inactive allele. By using the polymerase chain reaction technique (PCR), the CYP2A6 polymorphism was studied among Javanese Indonesian smokers. In the process of genotyping the CYP2A6*9 allele, some subjects who had been genotyped as CYP2A6*1/*4 in our previous studies were regenotyped as CYP2A6*9 in this study. The primer forward 2A6*9S and the primer reverse 2A6*9AS-wild type were used in these study. The Promega Go Taq Green Master Mix reagent were used to amplifl y the allele CYP2A6*1 in the positions at -395 to -28 of the CYP2A6 gene. The sample studied consisted of 20 smokers with Cigarrete per-Day (CPD) <10 and 13 smoker with CPD 11-20 from Javanese Indonesian population. In theses research, the subjects had been genotyped as CYP2A6*1/*4 in our previous studies. The allele frequencies of CYP2A6*1, CYP2A6*4, and CYP2A6*9 were 48.5%, 48.5%, and 3%, respectively. When these allele were considered simultaneously, among the subject, 63.9% were genotyped for CYP2A6*1/*4 and 6.1% were genotyped for CYP2A6*1/*4/*9. Based on the data collected, it could be concluded that the polymorphism of CYP2A6 among Javanese population sample study was not aff ected on smoking behavior.CYP2A6 merupakan salah satu enzim golongan sitokrom P450 yang memiliki bentuk polimorfi . Bentuk aktif enzim ini adalah CYP2A6*1, sedangkan bentuk alel CYP2A6*9 merupakan enzim yang memiliki penurunan aktivitas dan bentuk tidak aktif enzim ini adalah CYP2A6*4. Adanya bentuk polimorfi enzim ini dapat dideteksi menggunakan metode polymerase chain reaction technique (PCR). Pada penelitian ini, identifi kasi CYP2A6*9 dilakukan terhadap subjek uji yang pernah terlibat pada penelitian terdahulu dan telah teridentifi kasi memiliki genotipe CYP2A6*1/*4. Primer yang digunakan pada penelitian ini adalah primer forward 2A6*9S dan primer reverse 2A6*9AS-wild type. Proses amplifi kasi DNA pada posisi -395 sampai -28 dari gen CYP2A6 dilakukan menggunakan enzim Promega Go Taq Green Master Mix. Subjek uji berasal dari suku Jawa Indonesia yang terdiri dari 20 orang perokok dengan Cigarrete per-Day (CPD) <10 dan 13 smoker dengan CPD 11-20. Hasil penelitian menunjukkan frekuensi alel CYP2A6*1, CYP2A6*4, and CYP2A6*9 berturut-turut sebesar 48,5%; 48,5%; dan 3%. Bentuk genotipe CYP2A6*1/*4 diantara subjek uji sebesar 63,9%, sedangkan genotipe CYP2A6*1/*4/*9 sebesar 6,1%. Berdasarkan hasil penelitian ini, maka dapat disimpulkan bahwa adanya bentuk polimorfi CYP2A6 diantara subjek uji bersuku Jawa Indonesia yang diteliti tidak mempengaruhi perilaku merokok subjek uji
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Genetic Polymorphism of Cytochrome P450 2A6 Allele *4 and *9: Study on Glycohemoglobine Level Among Javanese Indonesian Smokers
Get PDFVariations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Pembangunan dan Implementasi Sistem Informasi Bank Darah di PMI dan RSUD Muntilan Kabupaten Magelang
Get PDFBlood bank administration in PMI, Magelang Regeency is still managed manually, which prevents hospitals from accessing information on blood stock quickly. Hospitals can access information about blood stock by phone only. Such a manual system could be a problem in delivering an excellent service. Therefore, a solution is required to improve the quality of services delivered by PMI. The use of information technology called Blood Bank Information System (SIBD/Sistem Informasi Bank Darah) is promising to improve the quality of services of the PMI. The SIBD helps the hospital to improve time efficiency in the blood demand process. There were several activities which have been completed, i.e.: 1) Developing SIBD at PMI of Magelang Regency; 2) Improving hardware facilities at PMI of Magelang Regency and RSUD Muntilan, including the procurement of computer hardware, modem, and Internet access for each institution; 3) Training on the use of SIBD for both PMI and hospital staff. The results wrer: 1). SIBD at PMI which is linked to RSUD Muntilan and other hospitals for blood supply information and online order; 2) Blood Bank Administration Database which can improve quality of service; 3) capability of PMI and RSUD Muntilan, Magelang Regency staff in utilizing SIBD to improve services to patients
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