41 research outputs found
Assessment of the Risk of Severe COPD Exacerbations:Balancing Between Fat and Muscle
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Differential Impact of Low Fat-Free Mass in People With COPD Based on BMI Classifications: Results From the COPD and Systemic Consequences-Comorbidities Network
No full textBACKGROUND: Alterations in body composition, including a low fat-free mass index (FFMI), are common in patients with chronic obstructive pulmonary disease (COPD) and occur regardless of body weight. RESEARCH QUESTION: Is the impact of low FFMI on exercise capacity, health-related quality of life (HRQL) and systemic inflammation different among COPD patients stratified in different body mass index classifications? STUDY DESIGN AND METHODS: We analysed baseline data of COPD patients from the COSYCONET (COPD and Systemic Consequences - Comorbidities Network) cohort. Assessments included lung function, bioelectrical impedance analysis, six-minute walk distance (6MWD), HRQL and inflammatory markers. Patients were stratified in underweight (UW), normal weight (NW), pre-obese (PO) and obese (OB) according to BMI and as presenting low, normal or high FFMI using 25th and 75th percentiles of reference values. Linear mixed models were used to investigate the associations between FFM and fat mass with secondary outcomes in each BMI group. RESULTS: 2137 COPD patients (GOLD 1-4, 61% males, age: 65±8years, FEV1: 52.5±18.8%pred) were included. The proportions of patients in UW, NW, PO and OB groups were 12.3%, 31.3%, 39.6%, 16.8%. The frequency of low FFMI decreased from lower to higher BMI groups (UW:81%, NW:53%, PO:42%, OB:39%). FFM was associated with the 6MWD in the UW group, even when adjusting for a broad set of covariates (P0.32). Fat mass was associated with higher systemic inflammation in the NW and PO groups (P<0.05). INTERPRETATION: In patients with COPD with lower weight, such as UW patients, higher FFMI is independently associated with better exercise capacity. In contrast, in PO and OB COPD patients, a higher FFMI were not consistently associated with better outcomes
Care Dependency in Non-Hospitalized Patients with COVID-19
No full textBackground: A large sample of "mild" COVID-19 patients still experience multiple symptoms months after being infected. These persistent symptoms are associated with many clinically relevant outcomes, including poor health status and impaired functional status. To date, no information is available about care dependency. Therefore, we aimed to explore the level of care dependency and the need for assistance with personal care in non-hospitalized COVID-19 patients. Methods: Members of two Facebook groups for COVID-19 patients with persistent complaints in The Netherlands and Belgium, and from a panel of people who registered at a website of the Lung Foundation Netherlands, were assessed for demographics, pre-existing comorbidities, health status, and symptoms. In addition, patients were asked about their dependence on others for personal care before and after the infection. The level of care dependency was assessed with the Care Dependency Scale (CDS) in members of the Belgian Facebook group (n= 210). Results: The data of 1837 non-hospitalized patients (86% women; median (IQR) age: 47 (38-54)) were analyzed. Only a small proportion of patients needed help with personal care before COVID-19, but the care need increased significantly after the infection (on average 79 +/- 17 days after the onset of symptoms; 7.7% versus 52.4%, respectively;p<0.05). The patients had a median (IQR) CDS score of 72 (67-75) points, and 31% of the patients were considered as care-dependent (CDS score</p
Avaliação do desempenho zootécnico do camarão branco do Pacífico alimentado com dietas com diferentes níveis de substituição de farinha de peixe por concentrado proteico de soja
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Aquicultura, Florianópolis, 2014.Avaliou-se o desempenho do camarão marinho Litopenaeus vannamei, quando alimentado com diferentes níveis de substituição (0, 25, 50, 75 e 100%) da proteína da farinha de resíduos de peixe (61,24 % PB) pela proteína do concentrado proteico de soja (63,07 % PB). O experimento teve duração de 42 dias, foi conduzido em água clara e foram utilizados 15 tanques de 800 L, dotados de sistema de aeração, aquecimento constante e renovação de água diária. Cada tanque foi povoado com 37,5 camarões/m3 (3,03±0,14 g). A alimentação foi fornecida quatro vezes ao dia, de acordo com 6% da biomassa inicial de cada tanque, sendo ajustada diariamente. O ganho em peso dos camarões alimentados com as dietas 0 e 25% de substituição proteica foi maior do que o apresentado pelos camarões alimentados com 100% de substituição, não havendo diferença (p>0,05) entre as demais dietas. A eficiência alimentar e a sobrevivência não diferiram (p>0,05) entre os camarões alimentados com as diferentes substituições proteicas. Houve uma tendência linear negativa para os parâmetros de crescimento e consumo com o aumento da substituição proteica com concentrado proteico de soja. Contudo, a proteína da farinha de resíduos de peixe pode ser substituída em até 75% pela proteína do concentrado proteico de soja, sem prejudicar o crescimento do camarão marinho L. vannamei.Abstract : We evaluated the performance of marine shrimp Litopenaeus vannamei when fed with different replacement levels (0, 25, 50, 75 and 100 %) of protein of fish meal (61,24% PC) by soybean protein concentrate (63,07% PC) in the feed. The experiment was conducted during 42 days in clear water in 15 tanks with 800 L, equipped with aeration, constant heating and daily water renewal. Each tank was stocked with 37,5 shrimp/m3 (3.03± 0.14 g). Feed was derived to four times daily according to biomass in each tank. Shrimp weight gain fed diets with 0 and 25 % substitution were greater than 100 %, but did not differ (p > 0.05) from the other diets. The feed efficiency and survival did not differ (p > 0.05) between diets. There was a negative linear trend with increasing replacement of fish meal for shrimp growth and feed consumption. However, results indicate that fish meal can be replaced up to 75 % without harming the growth of marine shrimp L. vannamei
Agreement and responsiveness of reference equations for the 6-min walk test in Brazilian patients with COPD
No full textConstruct validity of the Post-COVID-19 Functional Status Scale in adult subjects with COVID-19
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Generic and Respiratory-Specific Quality of Life in Non-Hospitalized Patients with COVID-19
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228922.pdf (Publisher’s version ) (Open Access
