143 research outputs found

    Patient-reported olfactory function following endoscopic sinus surgery with modified endoscopic Lothrop procedure / Draf 3

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    OBJECTIVES/HYPOTHESIS: The Modified Endoscopic Lothrop procedure (MELP) or Draf 3 is a complex procedure, performed for chronic frontal sinusitis that is refractory to standard functional endoscopic sinus surgery. The procedure involves drilling of the frontal T (formed by the septum and middle turbinate`s attachment to the skull base) onto the olfactory fossa often with exposure of the first olfactory neuron and may affect olfactory function. This study was performed to assess patients` subjective sense of smell following this procedure. STUDY DESIGN: Prospective study of retrospective data. METHODS: Sixty-eight patients, who underwent modified endoscopic Lothrop by the senior author (PJW) between 2003 and 2008, completed a post-operative questionnaire asking about their perception of olfactory function. All patients had their pre-operative subjective sense of smell documented prior to undergoing surgery. Patient records were reviewed for pertinent medical information such as the presence of asthma, aspirin sensitivity and nasal polyps. RESULTS: This study found that the majority of patients reported improvement in their sense of smell post-operatively, while only a small number reported a negative impact on their smell. Thirty-nine patients reported an improvement in their post-operative smell grade. Twenty patients reported no change in their smell grade, while the remaining 9 patients stated that their sense of smell worsened after surgery. No statistically significant correlation was found between patient outcome and the presence of asthma, nasal polyps, or Samter`s triad. CONCLUSIONS: The Modified endoscopic Lothrop procedure/Draf 3 had a positive effect on subjective sense of smell post-operatively in this cohort of patients.J. M. Yip, K. A. Seiberling, P. J. Wormaldhttp://www.ncbi.nlm.nih.gov/pubmed/2174388

    Review article: Towards multi-hazard and multi-risk indicators – a review and recommendations for development and implementation

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    Data availability: This review is based on previously published studies, and the data supporting the findings are derived from those sources. A summary of the data extracted and analysed is provided in the Supplement. Additional information is available from the corresponding author upon reasonable request.Supplement: The supplement related to this article is available online at https://doi.org/10.5194/nhess-25-4263-2025-supplement .The development of indicators in disaster risk management has only recently started to explicitly include a multi-hazard and multi-risk approach. However, undertaking a natural hazard or risk assessment from a single hazard approach can be considered incomplete where the interactions between, and impacts from, multiple hazards and risks are not considered. Indicators contain observable and measurable characteristics to simplify information to understand the state of a concept or phenomenon, and/or to monitor it over time. To understand how indicators are being used in this context, using a systematic review, we identified 192 publications that mention indicators within either multi-hazard or multi-risk contexts, including hazards, vulnerability, and risk/impact. We found that most studies exploring indicators focused on multi-layer single hazards and risks, where multiple single hazards or risks within a given location were analysed individually and their outcomes presented in an overlaid format. The results also demonstrate a predominance of studies on hazard indicators (88 %) versus risk indicators, with a dominance of hydrometeorological indicators. Only 20 % of the studies integrated hazard, vulnerability and risk/impact. Based on the findings, we propose a set of actionable recommendations to enable the development and uptake of multi-hazard and multi-risk indicators.This research has been supported by the Natural Environment Research Council (NERC) Global Partnerships Seedcorn Fund “EMERGE” project (grant no. NE/W003775/1). CJW, MSGA, MA, YC and CK were supported by the European Union's Horizon Europe “Multi-hazard and risk informed system for enhanced local and regional disaster risk management” (MEDiate) project under grant agreement no. 101074075. MSGA also received support from the Leverhulme Trust through an Early Career Fellowships under grant reference ECF-2023-074. RC, JC, MD, LS, and PJW were supported by the European Union's Horizon 2020 “Multi-hazard and sYstemic framework for enhancing Risk-Informed mAnagement and Decision-making in the E.U.” (MYRIAD-EU) project under grant agreement no. 101003276

    DIMUON PRODUCTION BY NEUTRINOS IN THE FERMILAB 15-FT. BUBBLE CHAMBER AT THE TEVATRON

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    The Fermilab 15-ft bubble chamber has been exposed to a quadrupole triplet neutrino beam produced at the Tevatron. The ratio of to in the beam is approximately 2.5. The mean event energy for -induced charged-current events is 150 GeV, and for -induced charged-current events it is 110 GeV. A total of 64 dimuon candidates (1+, 52 -+ and -, and 11 --) is observed in the data sample of approximately 13 300 charged-current events. The number and properties of the -- and + candidates are consistent with their being produced by background processes, the important sources being and K decay and punchthrough. The 90%-C.L. upper limit for --/- for muon momenta above 4 GeV/c is 1.2×10-3, and for momenta above 9 GeV/c this limit is 1.1×10-3. The opposite-sign-dimuono single-muon ratio is (0.62±0.13)% for muon momenta above 4 GeV/c. There are eight neutral strange particles in the opposite-sign sample, leading to a rate per dimuon event of 0.65±0.29. The opposite-sign-dimuon sample is consistent with the hypothesis of charm production and decay. © 1990 The American Physical Society.079 auteursSCOPUS: ar.jinfo:eu-repo/semantics/publishe

    COHERENT PRODUCTION OF pi+ pi- MESONS BY CHARGED CURRENT INTERACTIONS OF NEUTRINOS AND ANTI-NEUTRINOS ON NEON NUCLEI AT THE TEVATRON

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    Coherent single-pion production on neon nuclei is studied using the Fermilab 15-ft bubble chamber filled with a heavy Ne-H2 mixture and exposed to the Tevatron neutrino beam. In the neutrino energy range 40ε300 GeV, the net signal is 20±6 events, giving a corrected rate per charged-current event of (0.26±0.10)%. The cross section and kinematic distributions agree with the predictions of a model based on partial conservation of axial-vector current and meson dominance. © 1989 The American Physical Society.0SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Neutral strange particle production in antineutrino-neon charged current interactions

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    Neutral strange particle production in {Mathematical expression} Ne charged current interactions is studied using the bubble chamber BEBC, exposed to the CERN SPS antineutrino wide band beam. From a sample of 1191 neutral strange particles, the inclusive production rates are determined to be (15.7±0.8)% for K0 mesons, (8.2±0.5)% for Λ, (0.4±0.2)% for {Mathematical expression} and (0.6±0.3)% for Σ0 hyperons. The inclusive production properties of K0 mesons and Λ hyperons are investigated. The Λ hyperons are found to be polarized in the production plane. © 1992 Springer-Verlag

    Measurement and QCD analysis of neutral and charged current cross sections at HERA.

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    The inclusive e+p single and double differential cross sections for neutral and charged current processes are measured with the Hi detector at HERA. The data were taken in 1999 and 2000 at a centre- of-mass energy of √s 319 GeV and correspond to an integrated luminosity of 65.2 pb-1. The cross sections are measured in the range of four-momentum transfer squared Q² between 100 and 30000 GeV² and Bjorken x between 0.0013 and 0.65. The neutral current analysis for the new e+p data and the earlier e-p data taken in 1998 and 1999 is extended to small energies of the scattered electron and therefore to higher values of inelasticity y, allowing a determination of the longitudinal structure function FL at high Q² (110-700GeV²). A new measurement of the structure function xF3 is obtained using the new e+p and previously published e+p neutral current cross section data at high Q². These data together with Hi low Q² precision data are further used to perform new next-to-leading order QCD analyses in the framework of the Standard Model to extract flavour separated parton distributions in the proton. [ABSTRACT FROM AUTHOR

    First data with the ATLAS Level-1 Calorimeter Trigger

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    The ATLAS Level-1 Calorimeter Trigger is one of the main elements of the first stage of event selection for the ATLAS experiment at the LHC. The input stage consists of a mixed analogue/digital component taking trigger sums from the ATLAS calorimeters. The trigger logic is performed in a digital, pipelined system with several stages of processing, largely based on FPGAs, which perform programmable algorithms in parallel with a fixed latency to process about 300 Gbyte/s of input data. The real-time output consists of counts of different types of physics objects, and energy sums. The final system consists of over 300 custom-built VME modules, of several different types. The installation at ATLAS of these modules, and the necessary infrastructure, was completed at the end of 2007. The system has since undergone intensive testing, both in standalone mode, and in conjunction with the whole of the ATLAS detector in combined running. The final steps of commissioning, and experience with running the full-scale system are presented. Results of integration tests performed with the upstream calorimeters, and downstream trigger and data-flow systems, are shown, along with an analysis of the performance of the calorimeter trigger in full ATLAS data-taking. This includes trigger operation during the cosmic muon runs from before LHC start-up, and a first look at LHC proton beam data
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