187,580 research outputs found
Increase of Serum aú1-Acid Glycoprotein Despite the Decline of Liver Synthetic Function in Cirrhotics with Hepatocellular Carcinoma
No full textα,-Acid glycoprotein, an acute phase reactant synthesised by the liver, has been reported to be increased in neoplastic conditions and reduced in chronic liver disease. We measured serum aracid glycoprotein by a nephelometric method in 186 subjects (112 males, 74 females): 55 had mild chronic liver disease (chronic hepatitis and steatofibrosis), 45 cirrhosis, 38 hepatocellular carcinoma, 15 extra-hepatic malignant disease; 33 healthy subjects were used as controls. Analysis of variance demonstrated a significant variability among groups (F = 17.08, P = 0.0000). Higher concentrations of α1-acid glycoprotein were detected in malignant extra-hepatic disease than in all other groups (0.01); concentrations of α1-acid glycoprotein were higher in hepatocellular carcinoma than in cirrhosis (0.01). Multiple regression analysis by groups (dependent variable = αϊ-acid glycoprotein; group 1 = mild chronic liver disease + cirrhosis; group 2 = hepatocellular carcinoma) showed a significant correlation for both group 1 (r = 0.6264, F = 8.005, P = 0.0000) and group 2 (r = 0.8947, F = 13.643, P = 0.0000). The significant standardised regression coefficients were: cholinesterase, C-reactive protein, γ-glutamyltransferase and iron (negative) for regression upon group 1; C-reactive protein, α-antiproteinase, γ-glutamyltransferase, iron (negative) for regression upon group 2. A difference between the 2 regression equation coefficients was detected (F = 5.209, P = 0.0002). In conclusion, a raised aracid glycoprotein concentration was found in patients with malignancies, both hepatic and extra-hepatic; however, patients with hepatocellular carcinoma had a lower α1-acid glycoprotein concentration than patients with malignant extra-hepatic disease. In hepatocellular carcinoma, a good correlation existed between aracid glycoprotein and other serum indices of the acute phase response. In some patients with hepatocellular carcinoma, α1-acid glycoprotein was increased, despite the decrease of liver function. © 1993, Walter de Gruyter. All rights reserved
Tankefel vid utredningsarbete i fallet Thomas Quick
No full textEtt PM som listar ett antal tankefel i utredningsarbetet med fallet Thomas QuickA short paper with cognitive biases in the investigative work in the case of Thomas QuickEtt PM som baseras på uppgifter i Hannes Råstams bok "Fallet Thomas Quick. Att skapa en seriemördare" (Ordfront, 2012). </p
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Fallet Dan Waern [Elektronisk resurs] : pengarna, idealen och idrottsfamiljen
No full textLöparen Dan Waern är en i raden av idrottstjärnor som stängts av på livstid för brott mot amatörreglerna. Fallet blottar en sektliknade kultur inom delar av idrottsrörelsen.</p
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Mer om tankefel vid utredningsarbete i fallet Thomas Quick
No full textUtifrån undersökande journalisten Dan Josefssons bok "Mannen som slutade ljuga. Berättelsen om Sture Bergwall och kvinnan som skapade Thomas Quick" (Lind & Co, 2013) listas ett antal tankefel i utredningsarbetet kring de påstådda morden. En mycket läsvärd bok och viktig för att förstå hur fallet Thomas Quick uppkom genom avancerat missbruk av psykologi och psykoterapi av psykologer, läkare och psykoterapeuter. Som huvudinspiratör vid uppkomsten av fallet pekar materialet på psykoanalytikern Margit Norell. Uppkomsten utmärks av frånvaro av kritiskt tänkande hos många inblandade, dock inte alla.</p
Tankefel vid utredningsarbete i fallet Thomas Quick [Elektronisk resurs]
No full textEtt PM som listar ett antal tankefel i utredningsarbetet med fallet Thomas QuickA short paper with cognitive biases in the investigative work in the case of Thomas Quick</p
Mer om tankefel vid utredningsarbete i fallet Thomas Quick
No full textUtifrån undersökande journalisten Dan Josefssons bok "Mannen som slutade ljuga. Berättelsen om Sture Bergwall och kvinnan som skapade Thomas Quick" (Lind & Co, 2013) listas ett antal tankefel i utredningsarbetet kring de påstådda morden. En mycket läsvärd bok och viktig för att förstå hur fallet Thomas Quick uppkom genom avancerat missbruk av psykologi och psykoterapi av psykologer, läkare och psykoterapeuter. Som huvudinspiratör vid uppkomsten av fallet pekar materialet på psykoanalytikern Margit Norell. Uppkomsten utmärks av frånvaro av kritiskt tänkande hos många inblandade, dock inte alla.</p
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