251 research outputs found
Dataset for: Optimizing Treatment Expectations and Decision Making Through Informed Consent for Psychotherapy: A Randomized Controlled Trial
Dataset for the article: Gerke, L., Pauls, F., Ladwig, S., Liebherz, S., Reininger, K. M., Kriston, L., Trachsel, M., Härter, M., & Nestoriuc, Y. (2024). Optimizing treatment expectations and decision making through informed consent for psychotherapy: A randomized controlled trial.Journal of Consulting and Clinical Psychology, 92(2), 93–104. https://doi.org/10.1037/ccp0000851unknow
Interest Rate Pass-Through in Central and Eastern Europe: Reborn from Ashes Merely to Pass Away?
In this study, we seek to better understand the interest rate pass-through in five Central and Eastern European countries – the Czech Republic, Hungary, Poland, Slovakia and Slovenia, the CEE-5. Our pass-through estimates for several retail rates are generally lower than those reported in the literature, given the absence of cointegration between policy rates and long- or even short-term market rates. In addition, the pass-through has been declining over time in the CEE-5, and we argue that it is likely to decrease further in the future. Finally, the pass-through appears similar in the CEE-5 than in Spain and is higher than in core euro area countries. Hence, euro adoption by the CEE-5 would not further increase heterogeneity within the euro area with regard to the interest rate passthrough. However, substantially more research is needed to establish commonalities and differences between the CEE-5 and the euro area with respect to the reaction of prices and output to monetary policy action.interest rate pass-through, monetary transmission mechanism, transition economies, Central and Eastern Europe, Austria, Germany, Spain.
Reininger, Robert (28.09.1869-17.06.1955; Philosophie); 1936
sign. F 36
Unterschrift: RReininger
http://scopeq.cc.univie.ac.at/Query/detail.aspx?id=3675
Reininger, Louise (Death, 1900-02-21)
Address: 1643 Hamer St.Age at death: 63 yrs.Pg 17/1900/344/F W W/Germany/Dr. C.J. Finck/H. Osseforth/Vine St HillOriginal record filed in drawer labeled 'REIK-REMY'
The Plasmodium falciparum, Nima-related kinase Pfnek-4: a marker for asexual parasites committed to sexual differentiation
<b>Background</b>
Malaria parasites undergo, in the vertebrate host, a developmental switch from asexual replication to sexual differentiation leading to the formation of gametocytes, the only form able to survive in the mosquito vector. Regulation of the onset of the sexual phase remains largely unknown and represents an important gap in the understanding of the parasite's complex biology.
<b>Methods:</b>
The expression and function of the Nima-related kinase Pfnek-4 during the early sexual development of the human malaria parasite Plasmodium falciparum were investigated, using three types of transgenic Plasmodium falciparum 3D7 lines: (i) episomally expressing a Pfnek-4-GFP fusion protein under the control of its cognate pfnek-4 promoter; (ii) episomally expressing negative or positive selectable markers, yeast cytosine deaminase-uridyl phosphoribosyl transferase, or human dihydrofolate reductase, under the control of the pfnek-4 promoter; and (iii) lacking a functional pfnek-4 gene. Parasite transfectants were analysed by fluorescence microscopy and flow cytometry. In vitro growth rate and gametocyte formation were determined by Giemsa-stained blood smears.
<b>Results:</b>
The Pfnek-4-GFP protein was found to be expressed in stage II to V gametocytes and, unexpectedly, in a subset of asexual-stage parasites undergoing schizogony. Culture conditions stimulating gametocyte formation resulted in significant increase of this schizont subpopulation. Moreover, sorted asexual parasites expressing the Pfnek-4-GFP protein displayed elevated gametocyte formation when returned to in vitro culture in presence of fresh red blood cells, when compared to GFP- parasites from the same initial population. Negative selection of asexual parasites expressing pfnek-4 showed a marginal reduction in growth rate, whereas positive selection caused a marked reduction in parasitaemia, but was not sufficient to completely abolish proliferation. Pfnek-4- clones are not affected in their asexual growth and produced normal numbers of stage V gametocytes.
<b>Conclusions:</b>
The results indicate that Pfnek-4 is not strictly gametocyte-specific, and is expressed in a small subset of asexual parasites displaying high rate conversion to sexual development. Pfnek-4 is not required for erythrocytic schizogony and gametocytogenesis. This is the first study to report the use of a molecular marker for the sorting of sexually-committed schizont stage P. falciparum parasites, which opens the way to molecular characterization of this pre-differentiated subpopulation
Microfocusing at the PG1 beamline at FLASH
The Kirkpatrick-Baez (KB) refocusing mirror system installed at the PG1 branch of the plane-grating monochromator beamline at the soft X-ray/XUV free-electron laser in Hamburg (FLASH) is designed to provide tight aberration-free focusing down to 4 µm × 6 µm full width at half-maximum (FWHM) on the sample. Such a focal spot size is mandatory to achieve ultimate resolution and to guarantee best performance of the vacuum-ultraviolet (VUV) off-axis parabolic double-monochromator Raman spectrometer permanently installed at the PG1 beamline as an experimental end-station. The vertical beam size on the sample of the Raman spectrometer, which operates without entrance slit, defines and limits the energy resolution of the instrument which has an unprecedented design value of 2 meV for photon energies below 70 eV and about 15 meV for higher energies up to 200 eV. In order to reach the designed focal spot size of 4 µm FWHM (vertically) and to hold the highest spectrometer resolution, special fully motorized in-vacuum manipulators for the KB mirror holders have been developed and the optics have been aligned employing wavefront-sensing techniques as well as ablative imprints analysis. Aberrations like astigmatism were minimized. In this article the design and layout of the KB mirror manipulators, the alignment procedure as well as microfocus optimization results are presented
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A cross-case study exploring former school board member's perceptions when selecting and hiring a superintendent
The purpose of the present study was to explore the nature of hiring a public-school superintendent in a context, which challenged school board trustees to select a particular type of leader. The researcher’s intent was to study three former school board trustees who were initially involved in what they considered a complex change process, exploring their perceptions about change and the leader they hired to effect change. The use of a qualitative cross-case study comprised the appropriate research design for this approach to investigate a contemporary phenomenon, seeking to understand real-world context (Yin, 2018). Three questions guided the research, (a) What events/situations are characterized by school board trustees as needing change within a district? (b) From the perspective of the school board trustee, what skills, values, and competencies are important for the work of the superintendent to effect change? And (c) What mental models are used by school board trustees when hiring a superintendent? Data were initially organized into general themes, including, context, necessary change, and superintendent changes. Subsequently, a cross-case analysis generated several themes, including (a) Called to Serve, (b) Motivated by Concerns, (c) Committee to Purpose P, (d) Hiring Processes Utilized, and (e) Superintendent Staying Power, and (f) Gender Absence: A Constant Refrain. Implications for practice and future research were discussed.Educational Leadership, Curriculum & InstructionCollege of Education and Human Developmen
A new compact soft x ray spectrometer for resonant inelastic x ray scattering studies at PETRA III
We present a newly designed compact grating spectrometer for the energy range from 210 eV to 1250 eV, which would include the K amp; 945;1,2 emission lines of vital elements like C, N, and O. The spectrometer is based on a grazing incidence spherical varied line spacing grating with 2400 l mm at its center and a radius of curvature of 58 542 mm. First, results show a resolving power of around 1000 at an energy of 550 eV and a working spectrometer for high vacuum 10 amp; 8722;4 mbar environment without losing photon intensit
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