861 research outputs found
First person – Simona Amodeo
No full textABSTRACT
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Simona Amodeo is the first author on ‘Characterization of the novel mitochondrial genome replication factor MiRF172 in Trypanosoma brucei’, published in Journal of Cell Science. Simona is a PhD student in the lab of Torsten Ochsenreiter at the Institute of Cell Biology, University of Bern, Switzerland, investigating mitochondrial genome anchoring, replication and inheritance in Trypanosoma brucei.</jats:p
FOURIER-MUKAI TRANSFORMS FOR SINGULAR PROJECTIVE VARIETIES
No full textThis Ph. D thesis deals with various aspects of the theory of derived categories of sheaves on projective varieties. The first result is a generalization of a representability theorem by Lunts and Orlov for fully faithful functors where the source derived category is the derived category of sheaves over the double point scheme. The second result is a description of the space of stability conditions for the same derived category. The final result is a descend criterion for equivariant sheaves to the quotient variety with respect to an action by a finite group
Introduzione
No full textIl presente volume nasce dalla sinergia tra associazioni, istituzioni e ONG sviluppata nell’ambito della XVII settimana d’azione contro i razzismi, organizzata dall’Ufficio Nazionale Antidiscriminazioni della Presidenza del Consiglio dei Ministri. Nel testo sono riportate le trascrizioni delle relazioni tenute da docenti, militanti e practitioners che si occupano di richieste di protezione internazionale per motivi di identità sessuale durante il Convegno “I Have a Dream – Studi e strumenti per il lavoro con migranti LGBTI”.
La prima sezione raccoglie gli interventi delle istituzioni a vari livelli e delle organizzazioni non governative, dalla Presidenza del Consiglio dei Ministri, alla Regione, fino al Comune e dell’Alto Commissariato delle Nazioni Unite per i Rifugiati. Gli interventi sono intervallati da commenti e riflessioni critiche.
La seconda sezione contiene gli studi e le ricerche sul tema delle migrazioni queer in vari settori scientifico-disciplinari, dal- la sociologia, all’antropologia al diritto. Pur affrontando il tema prevalentemente in relazione alle migrazioni forzate, quindi alle richieste di asilo, sono riportati anche i risultati di riflessioni teoriche ed evidenze empiriche su migranti di prima e seconda generazione, non necessariamente asilanti o rifugiati. Ogni saggio breve è corredato da quattro testi di riferimento bibliografico.
Nella terza sezione sono riportate le relazioni di persone migranti LGBTIQ attiviste e di figure professionali che lavorano negli sportelli per richiedenti la protezione internazionale per motivi SOGIGESC
A MICROSCOPIC APPROACH TO THE STRUCTURE AND THERMODYNAMIC PROPERTIES OF PEPTIDES AND PROTEINS
No full textLa cittadinanza e l'immigrazione. Idee per una nuova disciplina italiana
No full textIl saggio analizza i possibili riferimenti di una nuova disciplina dei modi d'acquisto della cittadinanza in un contesto caratterizzato dall'immigrazione di massa e dalla crisi dei connotati della tradizionale idea di nazion
Observational study on dry period length and its associations with milk production, culling risk, and fertility in Italian dairy farms
No full textFrom an initial data set involving 84,189 lactations, this research evaluated the relationship between dry period length (DPL) and milk production, culling risk, and fertility. The data set included a total of 48,297 multiparous cow lactation records, with a calving event occurring in 2019 and 2020, belonging to 62 Italian herds with at least 150 cows. The DPL was classified into 5 categories (<40, 40-49, 50-60, 61-70, and >70 d) and these categories were used to establish the association between DPL and the outcome variables. All data obtained were assessed with simple and multiple linear regressions and Cox proportional hazard models. Cumulative milk production at 60 d in milk (DIM) was the highest in DPL categories of 61 to 70 d (2,480.29 kg/cow) and 50 to 60 d (2,474.39 kg/cow), and the lowest in <40 d (2,281.29 kg/cow). Similarly, DPL categories 61 to 70 d (10,830.94. kg/cow) and 50 to 60 d (10,817.48 kg/cow) had the highest 305-d milk production, whereas the <40 d (10,200.96 kg/cow) had the lowest one. The groups with a DPL of 40 to 49 d and >70 d had slightly, but significant, lower milk production both as cumulative 60 DIM and predicted 305-d milk production. Culling risk had a curvilinear behavior, with DPL <40 d and DPL >70 d showing significantly higher odds for culling during the first 60 DIM compared with DPL of 50 to 60 d [relative risk (RR): 1.53; RR: 1.46]. Within the same comparison, DPL of 61 to 70 d also had a slightly higher risk for culling (RR: 1.13). The DPL was associated also with fertility, with DPL of 40 to 49 d and 50 to 60 d having the greatest odds for pregnancy within the first 200 DIM. The DPL of <40, 61 to 70, and >70 d were negatively associated with fertility and showed pregnancy risks of 0.87, 0.95, and 0.94, respectively. This paper reinforces the importance of DPL as we demonstrated its association with milk production, culling, and fertility. Despite being attractive for high production dairy cows, very short dry periods are at the same time also associated with higher culling risk, lower milk production and fertility. Long DPL is detrimental, especially regarding culling and fertility. In summary, reducing variability in DPL and avoiding extremes by improving reproductive performance, maximizing late lactation milk production and making wise decisions on dry-off timing, may lead to better performances and lower early culling under Italian dairy conditions
Site-Specific Direct Labeling of Neurotrophins and Their Receptors: From Biochemistry to Advanced Imaging Applications
No full textWe describe here a versatile methodological platform to achieve site-directed and stoichiometry-controlled
labeling of neurotrophins and their receptors with various probes, ranging from biotin to small organic
dyes. This labeling method works in vitro on purified neurotrophins as well as in a living cell context,
where it achieves selective labeling of surface-exposed neurotrophin receptors. Here, we list all experimental
details of our labeling protocols, along with examples of the wide range of applications in which these
can be used
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