CORE
COnnecting
REpositories

    95 research outputs found

    In Nanette's garden [music] : piano solo /

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    B.2976 (Publisher number). Cover title.; Plate no. B.2976.; Also available online http://nla.gov.au/nla.mus-vn2291180; N, MUSM 142235; A,-
    National Library of Australia Digital Object Repository

    Genetics of schizophrenia and affective psychoses

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    PART 1 - THE GENETICS OF SCHIZOPHRENIA AND AFFECTIVE PSYCHOSES (pages 4- 69)This comprises an overview and critique of the work that led to the publications that form the thesis.PART 2 - THE REFERENCE LISTS OF THE PUBLICATIONS DISCUSSED, (pages 70-124)1987Kutcher, S.P., Blackwood, D.H.R., St. Clair, D.M., Gaskell, D.F., and Muir, W.J. (1987) Major author "Auditory P300 in borderline personality disorder and schizophrenia" Archives of General Psychiatry, 44: 645-6501988Blackwood, D.H.R., St. Clair, D.M., Muir, W.J., Oliver, C.J., and Dickens, P. (1988) Minor author "The development of Alzheimer's diseases in Down's syndrome assessed by auditory event-related potentials" Journal of Mental Deficiency Research, 32: 439-453 Muir, W.J., Squire, I., Blackwood, D.H.R., Speight, M.D., St. Clair, D.M., Oliver, C., and Dickens, P. (1988) "Auditory P300 response in the assessment of Alzheimer's disease in Down's syndrome: a two year follow-up study" Major author Journal of Mental Deficiency Research, 32: 455-4631989Blackwood, D.H.R., Muir, W.J., St. Clair, D.M., and Evans, H.J. (1989) Major author "Schizophrenia and chromosomes" (Letter) Lancet, ii: 1459 Kutcher, S.P., Blackwood, D.H.R., Gaskell, D.F., Muir, W.J., and St. Clair, D.M. (1989) Major author "Auditory P300 does not differentiate borderline personality disorder from schizotypal personality disorder" Biological Psychiatry, 26: 766-774 St. Clair, D.M., Blackwood, D.H.R., and Muir, W.J. (1989a) Major author "P300 abnormality in schizophrenic subtypes" Journal of Psychiatric Research, 23: 49-551990Blackburn, I.M., Roxborough, H.M., Muir, W.J., Glabus, M., and Blackwood, D.H.R. (1990) Minor author "Perceptual and physiological dysfunction in depression" Psychological. Medicine, 20: 95-103 St. Clair, D., Blackwood, D., Muir, W., Carothers, A., Walker, M., Spowart, G., Gosden, C., and Evans, H.J. (1990) Major author "Association within a family of a balanced autosomal translocation with major mental illness" Lancet, 336: 13-161991Blackwood, D., St. Clair, D., and Muir, W. (1991a) Major author "DNA markers and biological vulnerability markers in families multiply affected with schizophrenia" European Archives of Psychiatry and Clinical Neuroscience, 240: 191-196 Blackwood, D.H.R., St. Clair, D.M., Muir, W.J., and Duffy, J. (1991b) Major author "Auditory P300 and eye tracking dysfunction in schizophrenic pedigrees" Archives of General Psychiatry, 48: 899-909 Blackwood, D.H.R., Young, A.H., McQueen, J.K., Martin, M.J., Roxborough, H.M., Muir, W.J., St Clair, D.M., and Kean, D.M. (1991) Major author "Magnetic resonance imaging in schizophrenia: altered brain morphology associated with P300 abnormalities and eye tracking dysfunction" Biological Psychiatry, 30: 753-769 Morris, S.W., Muir, W., and St. Clair, D. (1991) Major author "Dinucleotide repeat polymorphism at the human tyrosinase gene" Nucleic Acids Research, 19: 69681993Evans, K.L., Fantes, J., Simpson, C., Arvelier, B., Muir, W., Fletcher, J., Van Heyningen, V., Steel, K.P., Brown, K.A., Brown, S.D.M., St. Clair, D., and Porteous, D. (1993) Minor author "Fluman olfactory marker protein maps close to tyrosinase and is a candidate gene for Usher syndrome type I" Human Molecular Genetics, 2: 115-118 Fletcher, J.M., Evans, K., Baillie, D., Byrd, P., Hanratty, D., Leach, S., Julier, C., Gosden, J.R., Muir, W., Porteous, D.J., St. Clair, D., and Van Heyningen, V. (1993) Minor author "Schizophrenia-associated chromosome 11 q21 translocation: identification of flanking markers and development of chromosome 11 q fragment hybrids as cloning and mapping resources" American Journal of Human Genetics, 52: 478-490 Roxborough, H.M., Muir, W.J., Blackwood, D.H.R., Walker, M.T. and Blackburn, I.M. (1993) Major author "Neuropsychological and P300 abnormalities in schizophrenics and their relatives" Psychological Medicine, 23: 305-3141994Blackwood, D.H.R., Ebmeier, K.P., Muir, W.J., Sharp, C.W., Glabus, M., Walker, M., Souza, V., Dunan, J.R., Murray, C., Dougall, N., and Goodwin, G.M. (1994) Major author "Correlation of regional cerebral blood flow measured by single photon emission tomography with P300 latency and eye movement abnormalities in schizophrenia" Acta Psychiatrica Scandinavica, 90: 157-166 Blackwood D.H.R., Muir, W.J., Roxborough, H.M., Walker, M.T., Townshend, R., Glabus, M., and Wolff, S. (1994) Major author "Schizoid personality in childhood: auditory P300 and eye tracking responses at follow up in adult life" Journal of Autism and Developmental Disorders, 24: 487-500 Dr Walter J Muir, Doctor of Science Thesis, the University of Edinburgh 75 Glabus, M.F., Blackwood, D.H.R., Ebmeier, K.P., Walker, M.T., Souza, V., Dunan, J.R., Sharp, C.W. and Muir, W.J. (1994) Major author "Methodological considerations in measurement of the P300 component of the auditory ERP in schizophrenia" Electroencephalography Clinical Neurophysiology, 90: 123-134 Morris, S., Leung, J., Sharp, C., Blackwood, D., Muir, W., and St. Clair, D. (1994) Major author "Screening schizophrenic patients for mutations in the amyloid precursor protein gene" Psychiatric Genetics, 4: 23-27 Sham, P.C., Morton, N.E., Muir, W.J., Walker, M., Collins, A., Shields, D.C., St. Clair, D.M., and Blackwood, D.H.R. (1994) Major author "Segregation analysis of complex phenotypes: an application to schizophrenia and auditory P300 latency" Psychiatric Genetics, 4: 29-38 Sharp, C.W., Muir, W.J., Blackwood, D.H.R., Walker, M., Gosden, C., St. Clair, D.M. (1994) Major author "Schizophrenia and mental retardation associated in a pedigree with retinitis pigmentosa and sensorineural deafness" American Journal of Medical Genetics, (Neuropsychiatric Genetics), 54: 354-3601995Brookes, A.J., Slorach, E.M., Evans, K.L., Thomson, M.L., Gosden, C.M., Muir, W.J., and Porteous DJ. (1995) Major author "Identifying genes within microdissected genomic DNA: Isolation of brain expressed genes from a translocation region associated with inherited mental illness" Mammalian Genome, 6: 257-262 de Souza, V.B.N., Muir, W.J., Walker, M.T., Glabus, M., Roxborough, H.M., Sharp, C.W., Dunan, J.R., and Blackwood, D.H.R. (1995) Major author "Auditory P300 event-related potentials and neuropsychological performance in schizophrenia and bipolar affective disorder" Biological Psychiatry, 37: 300-310 Evans, K.L., Brown, J., Shibasaki, Y., Devon, R.S., Arvelier, B., Christie, S., Maule, J.C., Baillie, D., Slorach, E.M., Anderson, S.M., Gosden, J.R., He, L., Petit, J., Weith, A., Gosden, C.M., Blackwood, D.H.R., St. Clair, D.M., Muir, W.J., Brookes, A.J., and Porteous, D.J. (1995) Minor author "A three megabase contiguous clone map on the long arm of chromosome 11 across a balanced translocation associated with schizophrenia" Genomics, 28: 420-428 He, L., Mansfield, D.C., Brown, A.F., Green, D.K., St. Clair, D.M., Muir, W.J., Morris, S.W., Wright, A.F., and Blackwood, D.H.R. (1995) Minor author "Automated linkage analysis in psychiatric disorders" American Journal of Medical Genetics, (Neuropsychiatric Genetics) 60: 192-198 Petit, J., Bosseau, P., Evans, K., Gosden, C., Muir, W., St. Clair, D., Porteous, D., and Arvelier, B. (1995) Minor author Seeding of YAC's over regions 1 q41 -42,3 and 11 q14.3-q23 with microdissection clones" European Journal of Human Genetics, 3: 351-3561996Battersby, S., Ogilvie, A.D., Smith, C.A.D., Blackwood, D.H.R., Muir, W.J., Quinn, J., Fink, G., Goodwin, G.M., and Harmar, A.J. (1996) Minor author "Structure of a variable number tandem repeat of the serotonin transporter gene and association with affective disorder" Psychiatric Genetics, 6: 177-181 Blackwood, D.H.R. Muir, W.J., Stevenson, A., Wentzel, J., Ad'hiah, A., Walker, M.T., Papiha, S.S., St. Clair, D.M., and Roberts, D.F., (1996) Major author "Reduced expression of HLA B35 in schizophrenia" Psychiatric Genetics, 6: 51-59 Harmar A.J., Ogilvie, A.D., Battersby S., Smith, C.A.D., Blackwood, D.H.R, Muir, W.J., Fink, G., and Goodwin, F.M. (1996) Minor author "The serotonin transporter gene and affective disorder" Cold Spring Harbor Symposia on Quantitative Biology, LXI: 791-795 He, L., Carothers, A., Blackwood, D.H.R., Teague, P., Maclean, A.W., Brown, J., Wright, A.W., Muir, W.J., Porteous, D.J., and St. Clair, D.M. (1996) Minor author "Recombination patterns around the breakpoint of a balanced 1:11 autosomal translocation associated with major mental illness" Psychiatric Genetics, 6: 201-208 He, L., Morris, S., Lennon, A., St. Clair, D.M., Porteous, D.J., Wright, A.F., Muir, W.J., and Blackwood, D.H.R. (1996) Major author "A genome-wide search for linkage in a large bipolar family: comparison of genotyping accuracy using di- and tetra-nucleotide repeat microsatellite markers" Psychiatric Genetics, 6: 123-129 Schizophrenia Linkage Collaborative Group For Chromosomes 3, 6, and 8: Levinson, D.F., Wildenauer, D.B., Schwab, S.G., Albus, M., Hallmayer, J., Lerer, B., Maier, W., Blackwood, D., Muir, W., StClair, D., Morris, S., Moises, H.W., Yang, L., Kristbjarnarson, H., Helgason, T., Wiese, C., Collier, D.A., Holmans, P., Daniels, J., Rees, M., Asherson, P., Roberts, Q., Cardno, A., Arranz, M.J., Vallada, H., McGuffin, D., Owen, M.J., Pulver, A.E., Antonarakis, S.E., Babb, R., Blouin, J.L., Demarchi, N., Dombroski, B., Housman, D., Karayiorgou, M., Ott, J., Kasch, L., Kazazian, H., Lasseter, V.K., Loetscher, E., Luebbert, H., Nestadt, G., Ton, C., Wolyniec, P.S., Laurent, C., Dechaldee, M., Thibaut, F., Jay, M., Samolyk, D., Petit, M., Campion, D., Mallet, J., Straub, R.E., Maclean, C.J., Easter, S.M., Oneill, F.A., Walsh, D., Kendler, K.S., Gejman, P.V., Cao, Q.H., Gershon, E., Badner, J., Beshah, E., Zhang, J., Riley, B.P., Rajagopalan, S., Mogudicarter, M., Jenkins, T., Williamson, R., DeLisi, L.E., Garner, C., Kelly, M., Leduc, C., Cardon, L., Lichter, J., Harris, T., Loftus, J., Shields, G., Comasi, M., Vita, A., Smith, A., Dann, J., Joslyn, G., Gurling, H., Kalsi, G., Brynjolfsson, J., Curtis, D., Sigmundsson, T., Butler, R., Read, T., Murphy, P., Chen, A.C.H., Petursson, H., Byerley, B., Hoff, M., Holik, J., Coon, H., Nancarrow, D.J., Crowe, R.R., Andreasen, N., Silverman, J.M., Mohs, R.C., Siever, L.J., Endicott, J., Sharpe, L., Walters, M.K., Lennon, D.P., Hayward, N.K., Sandkuijl, L.A., Mowry, B.J., Aschauer, H.N., Meszaros, K., Lenzinger, E., Fuchs, K., Heiden, A.M., Kruglyak, L., Daly, M.J., and Matise, T.C. (1996) Minor author "Additional support for schizophrenia linkage on chromosomes 6 and 8: a multicenter study" American Journal of Medical Genetics 67: 580-594 Schizophrenia Collaborative Linkage Group for Chromosome 22 (1996) - Gill, M., Vallada, H., Collier, D., Sham, P., Holmans, P., Murray, R., McGuffin, P., Nanko, S., Owen, M., Lasseter, V.K., Pulver, A.E., Meyers, D., Nestadt, G., Antonarkis, S., Housman, D, Childs, B., Straub, R., Su, Y., MacLean, C., Murphy, B., Wang, S., Walsh, D., Kendler, K., Polymeropoulos, M., Coon, H., Byerley, W., Gershon, E., Golden, L., Crow, T., DeLisi, L., Freedman, R., Reimherr, F., Wnder, P., Larent, C., Dumas, J-B., D'Amato, T., Jay, M., Martinez, M., Campion, D., Mallet, J., Wildenauer, D., Flallmayer, J., Lerer, B., Maier, W., Schwab, S., Ebstein, R., Gurling, H, Curtis, D., Blackwood, D., Muir, W., St. Clair, D., Fie, L., Maguire, S., Moises, Ft., Yang, L., Wiese, C., Kristbjarnson, Ft., Levinson, D., and Mowry, B. (1996) Minor author "A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at 22q12" American Journal of Medical Genetics (Neuropsychiatric Genetics) 67: 40-451997Lindholm, E., Cavelier, L., Ffowell, M., Eriksson, I., Jalonen, P., Adolfsson, R., Blackwood, D.FI.R., Muir, W.J., Brookes, A.J., Gyllensten, U., and Jazin, E.E. (1997) Minor author "Mitochondrial sequence variants in patients with schizophrenia" European Journal of Fluman Genetics, 5: 406-412 Mors, O., Ewald, FL, Blackwood, D., and Muir, W. (1997) Major author "Cytogenetic abnormalities on chromosome 18 associated with bipolar affective disorder or schizophrenia" British Journal of Psychiatry, 170: 278-280 Wilson-Annan, J.C., Blackwood, D.FI.R., Muir, W., Millar, J.K., and Porteous, D.J. (1997) Major author "An allelic association study of two polymorphic markers in close proximity to a balanced translocation breakpoint t(1 ;11) which co-segregates with mental illness" Psychiatric Genetics 7: 171-1741998Asherson, P., Mant, R., Williams, N., Cardno, A., Jones, L., Murphy, K., Collier, D.A., Nanko, S., Craddock, N., Morris, S., Muir, W., Blackwood, D., McGuffin, P., and Owen, M.J. (1998) Minor author "A study of chromosome 4p markers and dopamine D5 receptor gene in schizophrenia and bipolar disorder" Molecular Psychiatry, 3: 310-320 Doris, A.B., Wahle, K., MacDonald, A., Morris, S., Coffey, I., Muir, W., and Blackwood, D. (1998) Major author "Red cell membrane fatty acids, cytosolic phospholipase-A2 and schizophrenia" Schizophrenia Research, 31: 185-196 Millar, J.K., Brown, J., Maule, J.C., Shibasaki, Y., Christie, S., Lawson, D., Anderson, S., Wilson-Annan, J.C., Devon, R.S., St. Clair, D.M., Blackwood, D.H.R., Muir, W.J., and Porteous, D.J. (1998) Major author "A long-range restriction map across 3 Mb of the chromosome 11 breakpoint of a translocation linked to schizophrenia: Localisation of the breakpoint and the search for neighbouring genes." Psychiatric Genetics, 8: 175-182 Souery, D., Lipp, O., Serretti, A., Mahieu, B., Rivelli, S.K., Cavallini, C., Ackenheil, M., Adolfsson, R., Aschauer, H., Blackwood, D., Dam, H., Delcoigne, B., Demartelaer, V., Dikeos, D., Fuchshuber, S., Heiden, M., Jablensky, A., Jakovljevic, M., Kessing, L., Lerer B., Macedo, A., Mellerup, T., Milanova, V., Muir, W., Nylander, P.O., Oruc, L., Papadimitriou, G.N., Pekkarinen, P., Peltonen, L., Pinto De Azevedo, M.H., Pull, C., Shapira, R., Smeraldi, E., Staner, L., Stefanis, C., and Verga, M. (1998) Minor author "European collaborative project on affective disorders: interactions between genetic and psychosocial vulnerability factors" Minor author Psychiatric Genetics, 8: 197-205 Williams, J., Spurlock, G., Holmans, P., Mant, R., Murphy, K., Jones, L., Cardno, A., Asherson, P., Blackwood, D., Muir, W., Meszaros, K., Aschauer, H., Mallet, J., Laurent, C., Pekkarinen, P., Seppala, J., Stefanis, C.N., Papadimitriou, G.N., Macciardi, F., Verga, M., Pato, C., Azevedo, H., Crocq, M-A., Gurling, H., Kalsi, G., Curtis, D., McGuffin, P., and Owen, M.J. (1998) Minor author "A meta-analysis and transmission disequilibrium study of association between the dopamine D3 receptor gene and schizophrenia" Molecular Psychiatry, 3: 141-149 Vallada, H., Curtis, D., Sham, P., Kunugi, H., Zhao, J.H., Murray, R., McGuffin, P., Nanko, S., Owen, M., Gill, M., Collier, D.A., Antonarakis, S., Housman, D., Kazazian, H., Nestadt, G., Pulver, A.E., Straub, R.E., MacLean, C.J., Walsh, D., Kendler, K.S., DeLisi, L., Polymeropoulos, M., Coon, H., Byerley, W., Lofthouse, R., Gershon, E., Goldin, L., Freedman, R., Laurent, C., Bodeau-Pean, S., d'Amato, T., Jay, M., Campion, D., Mallet, J., Wildenauer, D.B., Lerer, B., Albus, M., Ackenheil, M., Ebstein, R.P., Hallmayer, J., Maier, W., Gurling, H., Curtis, D., Kalsi, G., Brynjolfsson, J., Sigmundson, T., Petursson, H., Blackwood D., Muir, W., St Clair, D., He, L., Maguire, S., Moises, H.W., Hwu, H.G., Yang, L., Wiese, C., Kristbjarnarson, H., Levinson, D.F., Mowry, B.J., Donis-Keller, H., Hayward, N.K., Crowe, R.R., Silverman, J.M., Nancarrow, D.J., Read, C.M. (1998) Minor author "A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12" Schizophrenia Research 32: 115-1211999Battersby, S., Ogilvie, A.D., Blackwood, D.H., Shen, S., Muqit, M.M., Muir, W.J., Teague P., Goodwin, G.M., and Harmar, A.J. (1999) Minor author "Presence of multiple functional polyadenylation signals and a single nucleotide polymorphism in the 3' untranslated region of the human serotonin transporter gene" Journal of Neurochemistry, 72: 1384-1388 Blackwood, D.H.R., Glabus, M.F., Dunan, J., O'Carroll, R.E., Muir, W.J., and Ebmeier, K.P. (1999) "Altered cerebral perfusion measured by SPET in relatives of schizophrenic patients: correlations with memory and P300" Major author British Journal of Psychiatry, 175: 357-366 Craddock, N., Lendon, C., Cichon, S., Culverhouse, R., Detera-Wadleigh, S., Devon, R., Faraone, S., Foroud, T., Gejman, P., Leonard, S., Mclnnis, M., Owen, M.J., Riley, B., Armstrong, C., Barden, N., van Broeckhoven, C., Ewald, H., Folstein, S., Gerhard, D., Goldman, D., Gurling, H., Kelsoe, J., Levinson, D., Muir, W., Philippe, A., Pulver, A., Wildenauer, D. (1999) Minor author "Chromosome Workshop: Chromosomes 11, 14, and 15" American Journal of Medical Genetics; Neuropsychiatric Genetics 88:244-254 Furlong, R.A., Rubinsztein, J.S., Ho L, Walsh, C., Coleman, T.A., Muir, W.J., Paykel, E.S., Blackwood, D.H.R., and Rubinsztein, D.C. (1999) Minor author "Analysis and meta-analysis of two polymorphisms within the tyrosine hydroxylase gene in bipolar and unipolar affective disorders" American Journal of Medical Genetics: Neuropsychiatric Genetics 88: 88-94 Hampson, R.M., Malloy, M.P., Mors, O., Ewald, H., Flannery, A.V., Morten, J., Porteous, D.J., Muir, W.J., and Blackwood, D.H.R. (1999) Major author "Mapping studies on a pericentric inversion (18) (p11.31 q21.1) in a family with both schizophrenia and learning disability" Psychiatric Genetics, 9: 161-163 Souery, D., Lipp, O, Mahieu, B., Rivelli, S.K., Massat, I., Seretti, A., Cavallini, C., Ackenheil, M., Adolfsson, R., Aschauer, H., Blackwood, D., Dam, H., Dikeos, D., Fuchshuber, S., Heiden, M., Jakovljevic, M., Kaneva, R., Kessing, L., Lerer, B., Lonnqvist, J., Mellerup, T., Milanova, V., Muir, W., Nylander, P.O., Oruc, L., Papadimitriou, G.N., Pekkarinen, P., Peltonen, L., Pull, C., Raeymaekers, P., Shapira, B., Smeraldi, E., Staner, L., Stefanis, C., Verga, M., Verheyen, G., Macciardi, F., Van Broeckhoven, C., and Mendelwicz, J. (1999) Minor author "Tyrosine hydroxylase polymorphism and phenotypic heterogeneity in bipolar affective disorder: a multicenter association study" American Journal of Medical Genetics (Neuropsychiatric Genetics), 88: 527-532 Visscher, P.M., Haley, C.S., Heath, S.C., Muir, W.J., and Blackwood, D.FI.R. (1999) Major author "Detecting QTLs for uni and bipolar disorder using a variance component method" Psychiatric Genetics, 9: 75-84.2000Serretti, A., Macciardi, F., Cusin, C., Lattuada, E., Souery, D., Lipp, O., Mahieu, B., Van Broeckhoven, C., Blackwood, D., Muir, W„, Aschauer, H.N., Heiden, A.M., Ackenheil, M., Fuchshuber, S., Raeymaekers, P., Verheyen, G., Kaneva, R., Jablensky, A., Papadimitriou, G.N., Dikeos, D.G., Stefanis, C.N., Smeraldi, E., and Mendlewicz, J. (2000) Minor author "Linkage of mood disorders with D2, D3 and TH genes: a multicenter study" Journal of Affective Disorders 58: 51-612001Borglum, A.D., Hampson, M., Kjeldsen, T.E., Muir, W., Murray, V., Ewald, H., Mors, O., Blackwood, D., and Kruse, T.A. (2001) Minor author "Dopa decarboxylase genotypes may influence age at onset in schizophrenia" Molecular Psychiatry, 6: 712-717 Devon, R.S., Anderson, S., Teague, P.W., Muir, W.J., Murray, V., Pelosi A.J., Blackwood, D.H.R and Porteous, D.J. (2001a) Minor author "The genomic organisation of the metabotropic glutamate receptor subtype 5 gene and its association with schizophrenia" Molecular Psychiatry 6: 311-314 Devon, R.S., Anderson, S., Teague, P.W., Burgess, P., Kipari, T.M.J., Semple, C.A.M., Millar, J.K., Muir, W.J., Murray, V., Pelosi, A.J., Blackwood, D.H.R., and Porteous, D.J. (2001b) Minor author "Identification of polymorphisms within disrupted in schizophrenia 1 and disrupted in schizophrenia 2, and an investigation of their association with schizophrenia and bipolar disorder" Psychiatric Genetics, 11: 71-78 Evans, K.L., Le Hellard, S., Morris, S.W., Lawson, D., Whitton, C., Semple, C.A.M., Fantes, J.A., Malloy, M.P., Maule, J.C., Humphray, S.J., Ross, M.T., Bentley, D.R., Muir, W.J., Blackwood, D.H.R., and Porteous, D.J. (2001) Major author "A 6Mb high-resolution BAC/PAC contig of human 4p15.3-16.1, a candidate region for bipolar affective disorder" Genomics 71: 315-323 Millar, J.K., Christie, S., Anderson, S., Lawson, D., Loh, D. H-W., Devon, R.S., Arveiler, B., Muir, W.J., Blackwood, D.H.R., and Porteous, D.J. (2001) Minor author "Genomic structure and localisation within a linkage hotspot of Disrupted in Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia" Molecular Psychiatry 6: 173-178 Muir, W.J., Thomson, M.L., McKeon P, Mynett-Johnson L, Evans, K.L., Porteous DJ and Blackwood, D.H.R. (2001) Major author "Markers close to the dopamine D5 receptor gene (DRD5) show significant association with schizophrenia but not bipolar disorder." American Journal of Medical Genetics 105:152-158 Lerer, B., Macciardi, F., Segman, R.H., Adolfsson, R., Blackwood, D., Blairy, S., Del Favero, J., Dikeos, D.G., Kaneva, R., Lilli, R., Massat, I., Milanova, V., Muir, W., Noethen, M., Oruc, L., Petrova, T., Papadimitriou, G.N., Rietschel, M., Serretti, A., Souery, D., Van Gestel, S., Van Broeckhoven, C., and Menlewicz, J. (2001) Minor author "Variability of 5-FIT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorder" Molecular Psychiatry, 6: 579-585 Souery, D., Van Gestel, S., Massa
    Edinburgh Research Archive

    Training tomorrow's aquatic leaders: A collaborative model in the Regional District of Nanaimo on Vancouver Island

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    The recruitment, training and retention of Lifeguard/Swimming Instructors is essential for the provision of safe and high quality aquatic programs. For years, recruitment, training and retention has become increasingly challenging. The issue was identified in Ontario, Canada, in 2005, and over the past ten years the issue has continued right across the country. The author, who works as an Aquatic Recreation Programmer for the Regional District of Nanaimo (RDN) on Vancouver Island, BC, has recently been dealing with this mounting problem. As a solution, the author, in collaboration with the local School District, developed an Aquatic Leadership Program (ALP). A school based curriculum was designed, allowing students to gain credits for aquatic leadership courses offered by the RDN. The ALP was a comprehensive concept approved by the School District and included Ministry of Education funding. A Pilot Project was initiated from February 2015 to June 2015. Eight students were accepted and of the eight students enrolled, six successfully completed the program, and three were hired by the RDN. Upon evaluating the program with the SD69 teachers involved, the ALP was deemed a success. The goals and objectives of both parties were met, and the outcomes established for the students were also met. However, there were some challenges identified throughout the program and these were addressed during the evaluation process. Solutions to the challenges were explored that will be integrated into the next ALP implementation. The ALP was beneficial to the RDN because it provided a group of trained and certified students able to apply for employment after completing the program. It was favourable to SD69 as it fit well with its mandate to provide students with alternative educational experiences to enhance their knowledge, skills and experience for future career choices. Most importantly, it was of significant advantage to the students who gained invaluable leadership skills and were well trained to obtain employment while attending school or upon graduation. Another important benefit of the ALP is its value to other communities facing similar staffing challenges. The author recently completed a Power Point presentation to the Canadian Red Cross. It was well received and there may be other stakeholders interested in hearing about the program including Parks and Recreation Associations and School Districts across Canada or internationally. The ALP can be an excellent solution to recruiting and retaining certified and qualified aquatic staff.https://viurrspace.ca/bitstream/handle/10613/19396/Porteous.pdf?sequence=
    VIURRSpace (Royal Roads University and Vancouver Island University)

    Examining factors that shape use and access to diverted prescription opioids during an overdose crisis : a qualitative study in Vancouver, Canada : [infographic]

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    This infographic is based on the following article : Bardwell, G., Ivsins, A., Socías, M. E., & Kerr, T. (2021). Examining factors that shape use and access to diverted prescription opioids during an overdose crisis: A qualitative study in Vancouver, Canada. Journal of Substance Abuse Treatment, 130, 108418. This undergraduate student work is a product of a collaboration between the Making Research Accessible initiative (MRAi), researchers, Dr. Evan Mauro and the students of ASTU 100 at UBC. This student work has been reviewed by the lead author of the original item. Revisions provided by the lead author have been incorporated into the student work with support from the UBC Learning Exchange and members of the MRAi. The reader should bear in mind that this is a student research project/report and is not an official document of UBC.Arts, Faculty ofUnreviewedUndergraduat
    University of British Columbia: cIRcle - UBC's Information Repository

    Author correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    Christina M. Lill, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this article. This has now been corrected in both the PDF and HTML versions of the article
    Julkari
    Revista Jurídica Digital UANDES
    Edinburgh Research Explorer
    UNSWorks
    Leiden University Scholary Publications
    The University of Manchester - Institutional Repository
    UQ eSpace (University of Queensland)
    Crossref
    Research Repository
    King's Research Portal
    HAL
    Oskar Bordeaux
    Portail HAL U-Bordeaux

    Behavior of ar plasma formed in a high-density plasma source - an ecr reactor

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    In order to develop the ultra-large scale integration(ULSI), low pressure and high density plasma apparatus are required for etching and deposit of thin films. To understand critical parameters such as the pressure, temperature, electrostatic potential and energy distribution of ions impacting on the wafer, it is necessary to understand how these parameters are influenced by the power input and neutral gas pressure. In the present work, a 2-D hybrid electron fluid-particle ion model has been developed to simulate one of the high density plasma sources-an Electron Cyclotron Resonance (ECR) plasma system with various pressures and power inputs in a non-uniform magnetic field. By means of numerical simulation, the energy distributions of argon ion impacting on the wafer are obtained and the plasma density, electron temperature and plasma electrostatic potential are plotted in 3-D. It is concluded that the plasma density depends mainly on both the power input and neutral gas pressure. However, the plasma potential and electron temperature can hardly be affected by the power input, they seem to be primarily dependent on the neutral gas pressure. The comparison shows that the simulation results are qualitatively in good agreement with the experiment measurements
    Institute Of Mechanics,Chinese Academy of Sciences

    Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    This work has been supported by: Motor Neurone Disease Association (G.B.M., S.C. and C.E.S.); Euan MacDonald Centre (G.B.M. and S.C.); European Research Council (L.V.); Cambridge Hospitals National Institute for Health Research Biomedical Research Center (L.V.).Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease for which a greater understanding of early disease mechanisms is needed to reveal novel therapeutic targets. We report the use of human induced pluripotent stem cell (iPSC)-derived motoneurons (MNs) to study the pathophysiology of ALS. We demonstrate that MNs derived from iPSCs obtained from healthy individuals or patients harbouring TARDBP or C9ORF72 ALS-causing mutations are able to develop appropriate physiological properties. However, patient iPSC-derived MNs, independent of genotype, display an initial hyperexcitability followed by progressive loss of action potential output and synaptic activity. This loss of functional output reflects a progressive decrease in voltage-activated Na+ and K+ currents, which occurs in the absence of overt changes in cell viability. These data implicate early dysfunction or loss of ion channels as a convergent point that may contribute to the initiation of downstream degenerative pathways that ultimately lead to MN loss in ALS.Peer reviewe
    Crossref
    Edinburgh Research Archive
    Edinburgh Research Explorer
    King's Research Portal
    University of St Andrews Research Portal
    University of St. Andrews - Pure
    St Andrews Research Repository

    Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (Nature Communications, (2018), 9, 1, (2098), 10.1038/s41467-018-04362-x)

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    Christina M. Lill, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this article. This has now been corrected in both the PDF and HTML versions of the article. © 2019, The Author(s)
    Pergamos : Unified Institutional Repository / Digital Library Platform of the National and Kapodistrian University of Athens

    Building scale in community impact investing through nonfinancial performance measurement

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    The measurement of nonfinancial performance is becoming increasingly important in the community impact investing industry, where individuals and institutions actively deploy capital in low-income domestic markets for both financial and social returns. Quality data ensure that the creation of jobs, construction of community facilities, financing of affordable housing, and other benefits that characterize the sector are delivered cost-effectively and transparently. This paper discusses the limited practice and future direction of nonfinancial performance measurement by revisiting four key questions: ; 1. Does nonfinancial performance measurement really matter for investors? ; 2. If it does matter, is nonfinancial performance measurement even possible? ; 3. If nonfinancial performance is possible to measure, what form should it take? ; 4. How will nonfinancial performance measurement increase community impact investing? ; The paper examines the barriers to a more robust regime of nonfinancial performance measurement and posits both that innovation in the sector ought to be driven by the discrete but explicit needs and demands of investors, and that greater accountability has a special role to play in making disclosure more attractive. The report concludes that nonfinancial performance measurement directly informs the investment process and is essential to growing community impact investing because it provides latent sources of capital with market-level information on the tradeoffs between financial and social return. Although the industry is unlikely to discover the “silver bullet” of nonfinancial performance measurement in the near future, there is reason to be hopeful: measurement strategies can – and will – converge through private- and public-sector innovation.Community development
    Research Papers in Economics

    What is the relationship between aphantasia, synaesthesia and autism?

    Author
    Publication venue
    Publication date
    Field of study
    No full text
    This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record Data statement The data is available from the corresponding author [CJD] upon request.For people with aphantasia, visual imagery is absent or markedly impaired. Here, we investigated the relationship between aphantasia and two other neurodevelopmental conditions also linked to imagery differences: synaesthesia, and autism. In Experiment 1a and 1b, we asked whether aphantasia and synaesthesia can co-occur, an important question given that synaesthesia is linked to strong imagery. Taking grapheme-colour synaesthesia as a test case, we found that synaesthesia can be objectively diagnosed in aphantasics, suggesting visual imagery is not necessary for synaesthesia to occur. However, aphantasia influenced the type of synaesthesia experienced (favouring ‘associator’ over ‘projector’ synaesthesia - a distinction tied to the phenomenology of the synaesthetic experience). In Experiment 2, we asked whether aphantasics have traits associated with autism, an important question given that autism – like aphantasia – is linked to weak imagery. We found that aphantasics reported more autistic traits than controls, with weaknesses in imagination and social skills.Arts and Humanities Research Council (AHRC)Leverhulme Trust Doctoral Scholarship ProgrammeUnion's Seventh Framework Programme (FP/2007–2013) / ERCChief Scientist Office of the Scottish Government Health DirectoratesScottish Funding Counci
    Sussex Research Online
    • …
    corecore