2,936 research outputs found
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Financial Summit: J.R. Briggs & Dave Briggs
No full textDave and J.R. Briggs speak on stewardship of finances.
Dave Briggs currently serves as the stewardship director at Central Christian Church of Arizona. Previously he served in a similar role at Willowcreek Church and prior to that was a finance manager for GE for 27 years. He has developed numerous financial seminars and classes and regularly speaks at churches and conferences around the country. Dave and his wife Debbie had two sons attend Taylor and served for three years on the Taylor Parents’ Cabinet.
J.R. Briggs wears a variety of ministry hats. On a local level, he serves as one of the pastors of The Renew Community. He is also the Founder and Director of Kairos Partnerships and Director of Leadership and Congregation Formation for the Ecclesia Network. He is a life coach, consultant, frequent speaker, and author of seven books. He and his wife Megan, along with their two sons Carter and Bennett, live in the Philadelphia area
The effect of turbulence on particle impaction om a cylinder in a cross flow
No full textParticle impaction on a cylinder in a cross flow is investigated with the use of Direct Numerical Simulations (DNS), with a focus on the effect of turbulence on the impaction efficiency. It is found that for particles with Stokes numbers in the boundary stopping mode there is up to ten times more front side impaction for turbulence with a large integral scale, than for a corresponding laminar flow. The back side impaction efficiency is also found to be influenced by the turbulence. The highest back side impaction efficiency is found for turbulence with small integral scales
Expression of an anti-CD33 single-chain antibody by Pichia pastoris
No full textCD33 is a cell surface glycoprotein expressed on cells of myelomonocytic lineage, leukaemic cells, but not haematopoietic stem cells. By virtue of its expression pattern, CD33 has become a popular target for new immunotherapeutic approaches to treat acute myeloid leukaemia. The methylotrophic yeast Pichia pastoris strain KM71H was used to produce an anti-CD33 single chain variable fragment (scFv), with the intention of conjugation to a radioisotope, for therapeutic use. To direct secreted expression of the anti-CD33-scFv the alpha-mating factor secretory signal sequence (alpha-MF) was used, with constructs containing a complete (CS) and incomplete (INCS) cleavage site to accommodate the potential outcomes of dibasic endopeptidase, Kex2, and dipeptidyl amino peptidase, Ste13, processing. The anti-CD33-scFv was expressed in BMMY cultures using both constructs, with a final yield of 48 mg/l (CS) and 11 mg/l (INCS). N-terminal sequencing showed that the CS-scFv had not been cleaved by Ste13, leaving amino acids EAEA at the N-terminus. The INCS-scFv construct produced a mixture of 50% authentic scFv and 50% with 11 amino acids from the alpha-MF remaining at the N-terminus. Despite the aberrations in alpha-MF processing, the anti-CD33-scFv's produced from both constructs were found to be functional. Flow cytometry and Biacore analysis demonstrated binding to target antigen CD33 on the surface of human leukaemic cell line HL-60, and to recombinant soluble CD33 respectively
J.R. Léveillé, 45th Annual ODU Literary Festival
No full textJ. R. Léveillé is a renowned figure in Franco-Manitoban and francophone literature. He is the author of over thirty interdisciplinary works of poetry, fiction, television documentaries and theater. He is included in many anthologies and his work is studied in many Canadian schools. His 2001 novel, The Setting Lake Sun (Le soleil du lac qui se couche) won the Prix Rue-Deschambault prize in 2002 and was selected for the 2020 edition of Le Combat des Livres. Some of his recent works include New York Trip (2003); Pierre Lardon (2011); Poème, Pierre, Prière (Poeme, Rock, Prayer, 2011); L\u27Invocation de Rutebeuf et the Villion (2012); Ganiishomong, ou l\u27extase du temps (2020) and Ex-Nihilo in 2021 with E.D. Blodgett. He was awarded the Manitoba Arts Council\u27s Award of Distinction in 2012
Romans en marge: les trois premières fictions de J.R. Léveillé
No full textLors de la publication des trois premières fictions de J.R. Léveillé: Tombeau (1968), La disparate (1975) et Plage (1984) – qui ont été rééditées dans l’oeuvre intitulée Romans –, la critique littéraire avait souligné le caractère d’avant-garde innovateur du style d’écriture de l’écrivain franco-manitobain. Issu d’un milieu minoritaire, et proposant des textes en marge du mainstream, J.R. Léveillé incarne, à notre avis, l’artiste postmoderne par excellence qui conçoit chaque «projet d’écriture» sous un nouvel angle expérimental. À l’instar de Rimbaud, J.R. Léveillé déploie différentes stratégies pour dérégler non seulement les sens, mais aussi «le sens», ou la cohérence attendue d’un récit. Une étude des procédés mis en oeuvre dans ces trois fictions nous permettra de voir, d’une part, comment le matériau premier du texte, à savoir les mots et les images, est manipulé par l’auteur et quel impact ces manipulations ont sur la cohérence attendue d’un récit. Nous espérons, d’autre part, pouvoir dégager la portée d’une telle écriture qui se renouvelle avec chaque nouveau titre en explorant la richesse de la marge, voire de «l’extrême marge».When the first three fictional works of Franco-Manitoban writer J.R. Léveillé were published (Tombeau, 1968, La disparate, 1975, and Plage, 1984, reissued in a single collection entitled Romans in 1995), literary critics pointed up the innovative, avant-garde character of Léveillé’s writing. J.R. Léveillé, a member of the French-speaking minority who produces writing that keeps resolutely to the fringes, is, in our opinion, the epitome of a post-modern artist, conceiving each new writing project from a new, experimental angle. Like Rimbaud, J.R. Léveillé deploys a variety of strategies to muddle not only the senses, but the meaning, direction, and coherency expected from a story. By examining the processes used in these three works of fiction, we will show, first of all, how the raw materials of the text—namely, the words and the images—are handled by the author, along with the impact that this handling has on the coherency expected from the story. Subsequently, we hope to flesh out the scope of such writing, which redefines itself with each new title, exploring the rich territory of the fringes, nay, the outer limits of the fringes
Within-person variation in coronary risk factors: implications for the aetiology and prevention of coronary heart disease.
No full textEpidemiological studies clearly demonstrate the importance of numerous risk factors for coronary heart disease (CHD), including blood lipids, blood pressure, cigarette smoking and physical inactivity. These factors are widely believed to account for only around 50% of CHD cases. However, "within-person" variation in coronary risk factors can affect the size and even direction of estimated aetiological relationships, and though these effects have been explored for the univariate relations of blood pressure and blood cholesterol, much uncertainty remains. In this thesis, data from the British Regional Heart Study, a prospective study of cardiovascular disease in middle-aged British men, is used to investigate the extent and effects of "within-person variation" in a range of coronary risk factors. The effects on estimated relations with CHD are examined and the combined importance of the major risk factors to CHD risk assessed. The potential effectiveness of different CHD prevention strategies, and the size and cause of social inequalities in CHD are also estimated. The findings reveal a high degree of within-person variation in both established and novel coronary risk factors. Taking within-person variation into account, CHD risk-relations for blood lipids, blood pressure, cigarette smoking and physical inactivity increase in magnitude though the estimated protective effect from moderate alcohol intake is reduced. After correction for within-person variation, blood cholesterol, blood pressure and cigarette smoking together account for at least 75 80% of CHD cases in British men. Moderate population-wide improvements in these risk factors could there fore greatly reduce population levels of CHD, while "high-risk" strategies, unless applied to a large proportion of the population, are likely to have only a limited effect. Narrow ing social inequalities in CHD would also have a comparatively modest effect on CHD compared with population-wide control of the key causal coronary risk factors
Forms of judaism in writings of F.R. Kraus, František Kafka, Hana Bělohradská and J.R. Pick
No full textTéma této práce zní Podoby židovství v dílech F.R. Krause, Františka Kafky, Hany Bělohradské a J.R. Picka. Soustředila jsem se na méně známé české autory, kteří se ve své tvorbě věnovali tématu židovství. Jedná se o texty související s 2. světovou válkou. V úvodu je nastíněn stručný přehled o působení Židů na našem území, následuje představení zvolené čtveřice autorů. Hlavním cílem bylo přiblížit a rozebrat vybraná díla a v závěru shrnout jejich odlišné a podobné znaky. Současně byly tyto texty zařazeny do kontextu české prózy s tematikou okupace.Katedra českého jazyka a literaturyObhájenoThe theme of this bachelor work is called Forms of judaism in writings of F.R. Kraus, František Kafka, Hana Bělohradská and J.R. Pick. In this thesis the author tried to concentrate on a few less-known Czech writers, who devoted their writing to the fate of Jews during the Second World War. In the first part of this work the author outlined the influence of the Jewish etnic group on the population of our country, with the aim to gain orientation in the historical backgound of that time. Next the author analysed the texts of selected books with the Jewish theme from different points of view and in the end of her work compared the books she used. In the closing of this work there is a contextual classification of the mentioned books into the category of works with the topic of occupation, from the end of the Second World War until today
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