10 research outputs found
Obat Nyamuk Bakar Berbahan Baku Limbah Batang Singkong Dan Ekstrak Biji Pala (Myritica fragans houtt)
In Lampung cassava stem waste is abundant, its existence is very disturbing, it is only thrown away and burned, it has not been utilized. Its use as an insect repellent is one of the value-added treatment efforts. The purpose of this study was to study the effect of tapioca glue adhesive concentration on the characteristics of mosquito coils at several concentrations of cassava stem powder and nutmeg powder. The treatment, the concentrations of cassava stem powder, nutmeg powder, and tapioca glue adhesive were; a) 16.67%, 26.04%, 58.34%, b) 16%, 24%, 60%, c) 15.38%, 23.07%, 61.53%, d) 14.81 %, 22.23%, 62.9%, and e) 14.28%, 22.32%, 64.28%. This research was conducted to study the physical characteristics (moisture content, density, shatter resistance index, combustion rate, smoke distribution, and organoleptic tests). The method used in this study was a completely randomized design measured using the Indonesian Industrial Standard (SII) No. 1113-84. The results showed that the variety of treatments with the addition of tapioca adhesive in the manufacture of mosquito coils had a very significant effect on moisture content, density, shatter resistance index, and burning time.Â
Modifikasi Mesin Peniris Minyak Sistim Tabung
The process of oil slicing is one process that can affect the oil content of the frying results. The remaining oil in fried foods when stored for a long time will cause a rancid odor. If consumed directly it will increase cholesterol levels. There are still many oil draining activities on the SME scale that still use traditional methods, namely by draining on the cage. In the previous study, a tube system slicing machine had been made with unhygienic washing machine scraping material. Existing tools can be upgraded by increasing the tube diameter. The research was carried out in several stages, namely: starting with modifying the drain tube, making a collection tube, making an oil outlet, making a frame and mounting an electric motor, making a transmission system, making an electrical system, assembling all the hardware and components. , testing the functional components, measuring the tube rotation of the drainer and testing the performance of the engine that was constructed. The tube was made with a diameter of 30, 35 and 40 cm. The cutting machine can function properly. The stability of the 40 cm diameter tube is better. The higher the tube the more unstable. From the results of testing to drain the 30-diameter diameter cassava chips can within 5 minutes reduce the oil content to 2.16%. Peniris diameter 35 cm 2.28%, peniris diameter 40 cm 2.35%. Keywords : Draining machine, oil, chip
Probable eculizumab-associated hepatotoxicity in a patient with neuromyelitis optica: A case report
ObjectivesNeuromyelitis optica (NMO) is an inflammatory, autoimmune and demyelinating disease of the central nervous system and is often characterized by attacks of severe optic neuritis and long segment myelitis. Identifying the disease-specific pathogenic anti-AQP4 autoantibody in NMOSD has allowed the development of highly effective disease-modifying drugs in the treatment phase. Eculizumab is a humanized antibody that binds to complement C5 and inhibits the formation of the C5b-induced membrane attack complex. It is approved for treating many diseases in which tissue damage is accompanied by complement (such as neuromyelitis optica, myasthenia gravis, autoimmune hemolytic anemia and paroxysmal hemoglobinuria).MethodsWe present a patient diagnosed with NMO who developed possible drug-induced liver injury three months after the start of eculizumab treatment.ResultAfter discontinuing eculizumab treatment, liver function tests gradually regressed in a month.ConclusionsEculizumab-associated hepatotoxicity is a previously unreported adverse event in NMOSD patients. Therefore, patients should be monitored for liver function tests during eculizumab treatment, and care should be taken for hepatotoxicity. If hepatotoxicity is detected while under eculizumab treatment, patients should be investigated for other drug use, complementary food supplementation, or possible autoimmune hepatitis, and other potential causes should be excluded
Performance Test of Cassava Cutting Machine Type of Double Block Cutter
Preparation of cassava seeds using a machete or hand saw takes a long time, the results are not uniform, and there is a potential for damage to cassava seedlings. The double block cutter type cassava stem cutting machine has been designed to produce high capacity and good quality cassava seeds. This study aims to test the performance of the cassava stem cutting machine with the double block cutter type. Performance tests include measuring machine working capacity, fuel consumption, seed uniformity, and planting test. The cutting test was carried out using 3 varieties of cassava seedlings. The machine works at a rotational speed of 3800 rpm and the test was carried out with various feeding loads, namely 3 rods, 4 rods, and 5 rods with. Each test was repeated 3 times. Cassava stem cutting machine (Petokong) is suitable for producing cassava stems with an average working capacity of 16275 seeds/hour. The results of the Anova test showed that the number of baits and varieties of cassava seeds and their interaction had a significant effect on the working capacity of the Petokong machine. Variations in fuel consumption are thought to be influenced by the variety of cassava stem used, which is influenced by the stem diameter of each variety. The Petokong machine is far superior to manual cutting using a machete or saw which can only produce 815 and 3005 seeds/hour per hour. The average fuel consumption is 1.82 liters per hour. Seed uniformity is about 98% and seedling damage can be minimized to 2%. The seeds produced by the Petokong machine can grow well, which is indicated by the appearance of shoots and an even distribution of roots
Evaluating floor types during simple composting of leaf wastes
This study aimed to evaluate the type of floor in the composting process of leaf wastes. The waste consisted of cacao leaves (Theobroma cacao L.), rubberwood leaves (Hevea brasiliensis), teak leaves (Tectona grandis L.f), matoa or Fijian longan leaves (Pometia pinnata), durian leaves (Durio zibethinus), and grass. The research was conducted by composting the leaf mixtures in a composting box sizing 220 cm in length, 180 cm in width, and 100 cm in height. A long box was partitioned by using plastic tarpaulin into four boxes for different floors, namely cement, soil, tarpaulin, and rice husks. A mixture of leaves of 127 kg to 176 kg was introduced in each box and was composted for 145 days. Variables observed were temperature, the height of heap, the mass of material (initial and final), C/N ratio, NPK contents, compost color, odor, pH, and moisture content. The results showed that compost quality fulfilled Indonesian National Standard (SNI 19-7030-2004) regardless of the floor types. However, the type of floors affected the compost process and yield. The composting process with tarpaulin-layered or husk-layered floors produced better compost in terms of N, P, C/N ratio, and color as compared to those resulting from cemented or barely soil floors
Characterization of Traditional Market Solid Waste (TMSW) and Its Recycling Potential (Case Study : Traditional Markets in Bandar Lampung)
Solid waste has always been a problem for developing countries. In Bandar Lampung, the traditional market is the second largest contributor of solid waste, after households. Data for Traditional Market Solid Waste (TMSW) composition and generation rate in Bandar Lampung is rarely found, even though, data is needed to write the policy for TMSW management and its recycling potential. This research aims to provide data on TMSW composition, generation rate and chararacteristic in Bandar Lampung, also its recycling potential. The sample from 10 of 31 traditional markets in Bandar Lampung is collected for 8 consecutive days in morning and afternoon. Then, the sample was processed to obtain its composition, generation and density. 48.06% of TMSW compositions is donated by vegetable. Meanwhile, metal is rarely found in traditional markets, with only 0.37%. The average density of TMSW is 180.11 kg/m3, while Kangkung Market has the highest density with 237.84 kg/m3 and Cimeng Market has the lowest TMSW density with 123.07 kg/m3. The generation rate of TMSW is 53,602.35 kg/day. Biodegradable wastes from traditional markets in Bandar Lampung, with 53% water contents, can be potentially recycled by composting and/or anaerobic digester because of its economic value and characteristic
ARTIFICIAL NEURAL NETWORK APPLICATION FOR THE ESTIMATION OF ANNUAL RAINFALL DATA UNRECORDED IN CISADANE WATERSHED
Naturally in a watershed rainfall distributes spatially. To know rainfall in the watershed needs information from many installed rain gauges. However, rainfall data is found not completely recorded. It is then important to estimate missing or unrecorded rainfall data. This study aims to estimate annual rainfall data in stations by using ANN (Artificial Neural Network). This study was conducted in Cisadane watershed. This study perfomed using rainfall data for 14 periods, the location of rainfall post (coordinates and elevation), DEM map, and watershed map. Data processing and analyzing performed using Ms. Excel 2010, ArcGIS 10.0, and BackPropogation Neural Network 1.0 program. Data used as input in ANN to estimates unrecorded rainfall data were coordinates (X,Y) and elevation (Z) of each rainfall post. ANN can be used to predict the amount of rainfall in cisadane watershed marked with a value of determination (R2) 0,97. After all data complete, average of rainfall in Cisadane watershed can be calculate using arithmetic, thiessen polygon, and isohyet. The amount of rainfall watershed in Cisadane using the arithmetic mean produce rainfall of 2.609 mm, with Thiessen Polygon of 2.539 mm, and with Isohyets of 2.594 mm. Keywords: ANN, annual rainfall, Cisadane watershed, estimation of rainfall
TEKNIK PENGENDALIAN SERANGGA HAMA WALANG SANGIT (Leptocorisa oratorius) MELALUI PENYEMPROTAN LARUTAN BEUVERIA BASSIANA UNTUK TANAMAN PADI
Characteristics of pain in patients with nmosd and mogad: Impact on mental health, sleep and quality of life
Neuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein-associated disease (MOGAD) are autoimmune disorders frequently accompanied by chronic, often neuropathic, pain, which significantly impacts the quality of life, sleep, and mental health. This study evaluated the incidence and characteristics of neuropathic pain in 106 patients with NMOSD or MOGAD and assessed its effects on mental health, sleep quality, and overall quality of life. Using clinical evaluation and MRI findings to localize lesions, pain classification revealed that chronic pain was more common in NMOSD patients (78.4%) than in MOGAD patients (52.7%), with a significant impact on both groups. Patients with MOGAD who experienced neuropathic pain reported notably poorer sleep quality and higher anxiety and depression levels. Pain severity was strongly associated with spinal cord lesion length and thoracic location, particularly in MOGAD patients. Current treatments provide insufficient pain relief, highlighting the need for more effective management strategies. This study emphasized that neuropathic pain substantially diminishes both physical and mental well-being in NMOSD and MOGAD patients, highlighting the importance of personalized pain management approaches to improve quality of life and mental health in these populations
Probable eculizumab-associated hepatotoxicity in a patient with neuromyelitis optica: a case report
Objectives: Neuromyelitis optica (NMO) is an inflammatory, autoimmune and demyelinating disease of the central nervous system and is often characterized by attacks of severe optic neuritis and long segment myelitis. Identifying the disease-specific pathogenic anti-AQP4 autoantibody in NMOSD has allowed the development of highly effective disease-modifying drugs in the treatment phase. Eculizumab is a humanized antibody that binds to complement C5 and inhibits the formation of the C5b-induced membrane attack complex. It is approved for treating many diseases in which tissue damage is accompanied by complement (such as neuromyelitis optica, myasthenia gravis, autoimmune hemolytic anemia and paroxysmal hemoglobinuria). Methods: We present a patient diagnosed with NMO who developed possible drug-induced liver injury three months after the start of eculizumab treatment. Result: After discontinuing eculizumab treatment, liver function tests gradually regressed in a month. Conclusions: Eculizumab-associated hepatotoxicity is a previously unreported adverse event in NMOSD patients. Therefore, patients should be monitored for liver function tests during eculizumab treatment, and care should be taken for hepatotoxicity. If hepatotoxicity is detected while under eculizumab treatment, patients should be investigated for other drug use, complementary food supplementation, or possible autoimmune hepatitis, and other potential causes should be excluded
