154,050 research outputs found
Res pública, constituição e liberdade no pensamento político de Marco Túlio Cícero
No full textTCC (graduação) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Curso de Ciências Sociais.A monografia tem por objeto a análise da definição de res publica no pensamento político de Cícero e, como consequência, das constituições e do conceito de liberdade. Encetando-se em meio a uma discussão entre Finley e Schofield sobre a questão da legitimidade, o presente trabalho advoga que a definição ciceroniana de res publica invoca uma série de preceitos básicos naturais aos quais o magistrado deve necessariamente seguir para que seu governo seja bom e justo – caracterizando uma res publica. Para tal estudo, fez-se imprescindível observar as características das constituições analisadas por Cícero, que são a base para definir o que é e o que não é uma república, bem como buscar compreender o significado de libertas, corolário indispensável para designar a melhor das repúblicas. É notável que, no pensamento de Cícero, não apenas há uma exigência de obrigação política perante os magistrados no que concerne ao governo da cidade, como, também, seria justificável destituir e até mesmo usar da violência com os governantes que não cumprirem sua obrigação política e com os elementos fundamentais que caracterizam uma res publica
Angiotensin II induces soluble fms-Like tyrosine kinase-1 release via calcineurin signaling pathway in pregnancy
No full textMaternal endothelial dysfunction in preeclampsia is associated with increased soluble fms-like tyrosine kinase-1 (sFlt-1), a circulating antagonist of vascular endothelial growth factor and placental growth factor. Angiotensin II (Ang II) is a potent vasoconstrictor that increases concomitant with sFlt-1 during pregnancy. Therefore, we speculated that Ang II may promote the expression of sFlt-1 in pregnancy. Here we report that infusion of Ang II significantly increases circulating levels of sFlt-1 in pregnant mice, thereby demonstrating that Ang II is a regulator of sFlt-1 secretion in vivo. Furthermore, Ang II stimulated sFlt-1 production in a dose- and time-dependent manner from human villous explants and cultured trophoblasts but not from endothelial cells, suggesting that trophoblasts are the primary source of sFlt-1 during pregnancy. As expected, Ang II-induced sFlt-1 secretion resulted in the inhibition of endothelial cell migration and in vitro tube formation. In vitro and in vivo studies with losartan, small interfering RNA specific for calcineurin and FK506 demonstrated that Ang II-mediated sFlt-1 release was via Ang II type 1 receptor activation and calcineurin signaling, respectively. These findings reveal a previously unrecognized regulatory role for Ang II on sFlt-1 expression in murine and human pregnancy and suggest that elevated sFlt-1 levels in preeclampsia may be caused by a dysregulation of the local renin/angiotensin system
Max Weber e o Liberalismo
No full textRes-Publica : Revista Lusófona de Ciência Política e Relações Internacionai
Eleições presidenciais nos Estados Unidos da América (EUA)
No full textRes-Publica : Revista Lusófona de Ciência Política e Relações Internacionai
A «Hora do Porto» na «Hora da Europa/Ibéria»(por esta ordem!) e na «Hora da Lusofonia» : os «10 Mandamentos» ou as «11 Teses» de e sobre o Porto
No full textRes-Publica : Revista Lusófona de Ciência Política e Relações Internacionai
Éditorial
No full textDepuis sept ans, la revue Res Futurae a eu maintes fois l’occasion de réaffirmer son engagement pour une étude de la science-fiction comme fait culturel global et intermédiatique. Les jeux vidéo, le cinéma, les séries télévisées ou l’illustration y ont été, et seront abordés comme autant de supports contribuant chacun pleinement, selon ce que Philippe Marion appelle leur médiagénie, à la dynamique de la SF. Il nous importe d’insister sur le fait qu’on ne saurait se contenter de voir l’image e..
O «choque Catalão» ou a «Hora» do advento das «Euro-Regiões» e do fim do «Estado-Nação»?
No full textRes-Publica : Revista Lusófona de Ciência Política e Relações Internacionai
A propósito do estatuto da Catalunha, razões para uma Independência
No full textRes-Publica : Revista Lusófona de Ciência Política e Relações InternacionaisAdmitirão as potências europeias um único estado ibérico? A independência de Portugal e não a da Catalunha, no seio da Península foi fruto de quê? Dos Aliados, da posição geográfica, e de que mais?Did the European great nations acknowledge a sole Iberian State? Portugal´s Independence and not Catalonia´s, among the Península was the result of what? Of the Allies, of the geographic position, and of what else
Introduzione e coordinamento della tavola rotonda “Dalle res communes omnium ai beni comuni”
No full textIntroduzione e coordinamento della tavola rotonda “Dalle res communes omnium ai beni comuni
Phasing out subsidies: Rendering the RES-e investments more self-sustained
No full textThe increasing shares of RES-e generation have resulted in unexpected but well-documented effects, such as the Merit Order Effect (MOE) on the power market. According to the MOE, the electricity prices decrease along with high penetrations of low variable cost technologies such as RES-e. Due to high investment costs the deployment of RES-e technologies is strongly depended on policy support. Upon lower electricity prices, generating profits becomes more and more challenging. Therefore, investors are more reluctant on financing such capital intensive projects. In consequence, further policy support is required to incentivize RES-e investments. However, subsidies are not expected to support the RES-e investments for an unlimited time but only for a certain time span during which the RES-e should evolve to self-sustained technologies. The design of the subsidy itself can contribute to tackling the negative impact of the MOE. The EU member states not only need to reduce the public support that is imposed by EU commission mandates, but at the same time have to ensure that they will meet the targets set for RES-e consumption in 2050 (European Commission, 2011). According to the abovementioned goals, two issues arise: a) how can the public support be reduced without challenging the RES-e generation? b) how can dependency on public support for the development on VREs be eliminated? To tackle these issues, the present thesis comes with the objective to provide recommendations regarding policy support without challenging the deployment of VREs. To deliver the objective an agent based model designed by the Energy and Industry Section of TPM faculty of Delft University of Technology called EMLab Generation was employed. The model is built to study the transition of the European Energy markets towards a carbon-free regime. To deliver the thesis objective six scenarios were tested- five including policy support and one Base Case scenario in which no subsidies are provided. The following KPIs were measured to provide answers to the research question and sub-questions: investor profits per energy unit, spot market revenue per energy unit, mean subsidy per energy unit, ratio of RES-e to total generation, production per technology, average electricity price for each year of the simulated period and aggregated profits and subsidy costs during the entire modeled period. The findings suggest that the optimum subsidy scheme to reduce public support is provided by the FIP Ex Post scenario according to which the mean paid subsidy decreases with time. Regarding the insight for energy investors, more profits are generated when investments only in RES-e technologies are realized. The reason for the latter is that investments in CCGT plants result in losses. This is explained by the exclusion of CCGT technology from the market due to the high penetration of the zero marginal cost RES-e technologies. RES-e technologies are first in the merit order and therefore have priority on supplying the electricity market. Consequently, as more RES-e technologies are implemented the lesser, is the load needed to be supplied by other sources. Finally, regarding the value of storage in the energy market the only remarkable effect is the smoothening of electricity prices which still is not observed when storage capacity increases from 20gwh to 40gwh.Technology, Policy and ManagementEngineering, Systems and ServicesManagement of Technolog
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