298 research outputs found
Directing Betrayal
No full textAn account of my preparation for and production of Harold Pinter's Betrayal in Levin Theater in the Fall of 2009.M.F.A.Includes summaryby Maryna E. HarrisonIncludes bibliographical references (p. 99-100
Correction to: Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study
No full textAbstract After publication of this work [1] it was noticed three author names were spelt incorrectly. Liudmila Iashyna should be Liudmyla Iashyna, Marina Polyanskaya should be Maryna Polianska and Elcan Mamamdbayov should be Eljan Mammadbayov
Життєві перипетії і творча спадщина поетеси української діаспори США Марини Приходько (Life and Artistic Heritage of Maryna Prykhodko, the Poetess of the Ukrainian Diaspora in US)
No full textАвтором досліджено життєвий та творчий шлях відомої діаспорної поетеси Марини Приходько. Народжена на еміграції у Празі в міжвоєнний період, майбутня літераторка проживала у різних країнах Європи – Чехословаччині, Польщі, Німеччині, була в’язнем нацистського концентраційного табору Гросс Розен, а у 1950-х емігрувала до США. Проаналізовано творчу спадщину М. Приходько, частими мотивами якої була туга за рідним краєм, про який вона знала лише через розповіді батьків. У тезах розглянуто, що поезія також виступає яскравим індикатором внутрішнього стану поетеси, способом реакції на непрості події, що супроводжують людину у її житті.
(The author studies the life and career of Maryna Prykhodko, a famous Ukrainian diaspora poetess. She was born in exile in the interwar period in Prague and lived in various European countries like Czechoslovakia, Poland and Germany. Maryna Prykhodko was a prisoner in Gross-Rosen concentration camp and immigrated to the United States in 1950. The article analyses Prykhodko’s literary heritage. It is stressed that the frequent motifs of her poems are homesickness for homeland about which she knew only from her parents stories. Moreover, the author of the research confirms that poetry reveals her internal feelings and reflects her reaction to difficult events in her life.
Determination of the value of the company uab „x” by the discounted cash flow method.
No full textDetermination of the Value of the Company UAB „X” by the Discounted Cash Flow Method Maryna KOSOBUCKAJA Paper for the Bachelor’s degree Banking Bachelor’s Program Vilnius University, Faculty of Economics, Finanace Department Supervisor – prof. Dr. A. Paškevičius Vilnius, 2020 SUMMARY 58 pages, 8 pictures, 24 tables, 32 references. The main goal of this bachelor's thesis is to determine the value of UAB "X" company using the discounted cash flow method and to try to calculate the value of the company by assessing the impact of the coronavirus epidemic. The work consists of three main parts; literature analysis, research and its results, conclusions and recommendations. The analysis of the literature describes the concept of company value, discusses the objectives and methods of valuation, and compares valuation methods. The second part of this work describes the research methodology, discusses the main stages of the discounted cash flow valuation method. This work was written to calculate the value of the company by discounting cash flows under emerging market conditions and quarantine conditions that were introduced due to the coronovirus pandemic in Lithuania in 2020. March 16 The cash flow forecast showed that the value of the company obtained using the discounted cash flow method was EUR 47,814,340 in the stage of stable economic development and EUR 944,880 if the company would work under quarantine conditions for 3 years. The results of the calculated second value were so insignificant that even without additional calculation it was clear that this value could not be correct. Therefore, the company's value calculation methodology was adjusted to the DCF method and a result of EUR 27 312 940 was obtained. The conclusions and recommendations summarize the main concepts of the literature analysis and the results of the research. The author believes that the DCF assessment cannot be mechanically transferred to the method, the company history, economic forecasts, company manager and expert forecasts need to be taken into account
Definite / indefinite and retrospective / prospective categories as representation of the image of the author in the story titled «Dear Shura» by T. Tolstaya
No full textThe article deals with the «image of the author» considered as central semantic category in
modern philology. Implicit character of this category in most cases makes interpretation difficult for
readers. As central category of art text the «image of the author» interacts with different categories
for example definite / indefinite and retrospective / prospective categories.
In the story «Dear Shura» by T. Tolstaya definite / indefinite categories typically represented
by pronouns on the grammatical level create the «image of the author». The oppositions of definite
and indefinite meanings show characteristics’ changings of the «image of the author» significant for
the text sense. The retrospective category gives to the reader an opportunity to realize the repetitive
semantic conceptual information as the most significant one from the author’s point of view. Perfect
productive forms and their oppositions with other verbal forms make different characteristics
of the «image of the author». Also adequate interpretation of the analysed art text is possible by
prospective category represented by imperative verbal forms. Stylistically marked use of pronouns
and verbal forms in the aspect of analysed categories as the identifying factor of the «image of the
author» is pointed out.В статье анализируется центральная семантическая категория «образ автора», имплицитный характер которой во многих случаях затрудняет интерпретацию художественного
текста читателем. Являясь центральной категорией художественного текста, образ автора
взаимодействует с различными категориями, в том числе категориями определённости / неопределённости и ретроспекции / проспекции.
В рассказе Т. Толстой «Милая Шура» категория определённости / неопределённости частотно репрезентируется местоимениями различных разрядов, оформляющими образ автора.
Оппозиция значений определённости / неопределённости отмечают изменения характеристик образа автора, значимых для восприятия смысла текста. Категория ретроспекции даёт
читателю возможность осознать повторяющуюся концептуальную информацию как наиболее существенную с авторской точки зрения. Формы перфектного результативного и их оппозиции с другими глагольными формами также выявляют образ автора. Кроме того, адекватная интерпретация анализируемого художественного текста обеспечивается категорией проспекции, выраженной глагольными формами в императивном наклонении. Таким образом,
в статье обосновывается роль стилистически маркированного использования местоимений
и глагольных форм в аспекте анализируемых категорий как фактора выявления образа автора
Decentralization in Ukraine and Bottom-Up European Integration
No full textAuthor´s accepted manuscript.Available from 30/07/2023.acceptedVersio
Laboratory changes and levels of biomarkers in localized bacterial infections and sepsis in children
No full textPypa Larysa, Murhina Maryna. Laboratory changes and levels of biomarkers in localized bacterial infections and sepsis in children. Journal of Education, Health and Sport. 2017;7(8):701-711. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.885397
http://ojs.ukw.edu.pl/index.php/johs/article/view/4779
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017).
1223 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Authors 2017;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 01.08.2017. Revised: 02.08.2017. Accepted: 28.08.2017.
LABORATORY CHANGES AND LEVELS OF BIOMARKERS IN LOCALIZED BACTERIAL INFECTIONS AND SEPSIS IN CHILDREN
Larysa Pypa, Maryna Murhina
National Pirogov Memorial Medical University, Vinnytsya
For correspondence: Maryna Murhina Assistant, Department of Pediatrics, Faculty of Postgraduate Education, National Pirogov Memorial Medical University, Vinnytsya,
Pirogov st. 54, 21037, Ukraine; fax:(0432) 35-05-63; e-mail: [email protected]; phone +38 (067) 3356694.
Abstract
Background. The success of sepsis treatment depends on early diagnosis of the generalization of bacterial infection, but the nonspecificity of clinical manifestations often makes the diagnosis delayed. Therefore, the search for highly specific and sensitive biomarkers for early diagnosis of sepsis is relevant. The aim of our research is investigate the laboratory features and diagnostic value of a number of modern biomarkers for the diagnosis of sepsis in children.
Materials and methods. of general laboratory studies and determination of CRP level were performed in 115 children with generalized and localized forms of bacterial infections. The main group (47 children) - children with sepsis, a comparison group (68 children) - with a localized bacterial infection of various localization. The age of children was from 1 month. up to 18 years. Grouping was performed according to the presence of signs and symptoms of SIRS and organ dysfunction. Determination of the level of procalcitonin and TNF-α was performed in 31 children of the main group, 45 children in the comparison group and 30 children in the control group (children without signs of inflammation). Prespepsin levels were determined in 16 main group children, 14 in the comparison group and 26 in the control group.
Results. During the study, it was found that the level of leukocytosis was much higher and continued 2.6 times longer in the main group than in the children of the comparison group (p <0.01).Anemia was found in 76.6% of the children in the main group, while in the comparator group, the anemia syndrome was diagnosed 3.7 times less frequently. In the study of CRP in the main group, its level reached 44.7 mg / l and 28.3 mg / l in the comparison group, the specificity and sensitivity for diagnosis of sepsis was 46.8% and 51.5% respectively. The mean TNF-α level in children in the main group was 280.3 pg / ml CI 95% [243.9-316.7], which was 1.5 times higher than in children with a localized bacterial process, where the average level of this cytokine was 186.5 pg / ml CI 95% [163.1-209.9], and 4.2 times higher than that of control group children (65.7 pg / ml CI 95% [56.7-74, 8]). The difference between the groups was statistically significant (p <0.01). Sensitivity and specificity were 61 and 81% (for sepsis diagnosis).
In the main group of children, the mean PCT level was 4.06 ng / ml CI 95% [3.34-4.69], and in the comparison group - 0.86 ng / ml CI 95% [0.77-1.03] , in the group of control - 0.024 ng / ml CI 95% [0.02-0.03], between the groups the difference was statistically significant (p <0.01). Sensitivity and specificity were 87% and 90%. The level presepsin in the main group was 1887.5 pg / ml (505.5-3702.5 pg / ml); in the comparator group, 313.5 pg / ml (208-376 pg / ml), in healthy children, the level of presepsin was 109 pg / ml (77.5-160 pg / ml). The difference between the groups is statistically significant (p <0,01). The sensitivity and specificity of determination the level of presepsin in children with sepsis is 92% and 93%, respectively.
Conclusions
1. In children with sepsis, leukocytosis is more pronounced in comparison with children with localized bacterial infection, but there is no clear regularity between the severity of the septic state and the magnitude of leukocytosis.
2. Anemia is accompanied by septicemia in almost 76,6% of cases,
3. The most sensitive and specific markers for the development of sepsis are procalcitonin and presepsin and for the diagnosis of bacterial infection, the level of serum presepsin is the most specific and sensitive.
Key words: sepsis, presepesin, procalcitonin, CRP, childre
Наукові можливості Інтернету речей для покращення життя людини
No full textThis work discusses the scientific opportunities presented by the Internet of Things (IoT) to improve human life across various domains. IoT connects devices, sensors, and machines, enabling them to collect and share data, leading to intelligent systems that can automate tasks, optimize resource usage, and improve communication. The author highlights potential benefits in education, healthcare, smart cities, industry, and tourism
Профілактика методом аерозолю бронхопневмонії та її вплив на виробничі показники телят
No full textThe aim: to determine the effectiveness of aerosol prophylaxis of nonspecific bronchopneumonia in calves by using a complex of biogenic compounds of macro- and microelements and plant immunomodulator Echinacea in the form of the drug Kalfmin on production indicators.
Materials and methods. The research was conducted in the farm "Podilsky owner 2004", v. Velyka Medvedivka, Shepetivka district, Khmelnitsky region on black-spotted calves, which were in the risk group for bronchopneumonia, taking into account certain technological components, namely – stress due to regrouping of animals, some adjustment of their feeding rations, some excess concentration of livestock animals in groups and other factors.
Results. The results of studies indicate a high therapeutic efficacy for the use of the drug "Kalfmin" group aerosol method in the treatment of patients with calf bronchopneumonia, as this drug enters the body in the same way as pathogens. It was found, that 40 % of calves in the control group, which did not receive preventive measures, have clinical signs of bronchopneumonia, and 10 % of cases were fatal. At the same time, signs of bronchopneumonia were found in only 10 % of calves in the experimental groups, who received aerosol prophylaxis according to the experimental scheme; their course was much easier and without fatal consequences.
Conclusions. Prevention of bronchopneumonia in young cattle should be comprehensive and aimed at eliminating violations of the technology of keeping, feeding and increasing the resistance of animals. Group aerosol prevention of nonspecific bronchopneumonia in calves using the drug Calfmin in combination with the plant immunomodulator Echinacea is a more promising and effective method of preventing this pathology compared with the use of turpentine, lactic acid and chlorinated lime. The use of the drug Kalfmin in combination with Echinacea is characterized by 1.60 time’s higher efficiency and 1.70 times shorter period of prevention of animalsМета: визначити ефективність впливу аерозолепрофілактики неспецифічної бронхопневмонії в телят шляхом застосування комплексу біогенних сполук макро- і мікроелементів та рослинного імуномодулятора ехінацеї у вигляді препарату Кальфмін на виробничі показники.
Матеріали і методи. Дослідження проводились у господарстві «Подільський господар 2004», с. Велика Медведівка, Шепетівського району, Хмельницької області на телятах чорно-рябої породи, які входили до групи ризику щодо захворювання на бронхопневмонію, враховуючи окремі технологічні складові, а саме – стрес внаслідок перегрупування тварин, певне корегування через це раціонів їх годівлі, деяке перевищення концентрації поголів’я тварин у групах утримання та інші фактори.
Результати. Результати досліджень вказують на високу терапевтичну ефективність щодо застосування препарату «Кальфмін» груповим аерозольним методом під час лікування хворих на бронхопневмонію телят, так як цей лікарський засіб надходить в організм тими ж шляхами, що і збудники хвороби. Виявили, що в 40 % телят контрольної групи, яким не застосовували заходи профілактики, наявні клінічні ознаки бронхопневмонії, а 10 % випадків закінчилися летально. В той же час, ознаки бронхопневмонії було встановлено лише в 10 % телят дослідних груп, яким застосовували профілактику методом аерозолю згідно схеми досліду, їх перебіг був значно легший та без летальних наслідків.
Висновки. Профілактика бронхопневмонії у молодняку великої рогатої худоби має бути комплексною і спрямованою на усунення порушень технології утримання, годівлі і підвищення резистентності організму тварин. Групова аерозольна профілактика неспецифічної бронхопневмонії телят з використанням препарату Кальфмін у комплексі з рослинним імуномодулятором ехінацеєю, є більш перспективним і ефективним методом попередження цієї патології порівняно із застосуванням з цією метою скипидару, молочної кислоти та хлорного вапна. Застосування препарату Кальфмін у комплексі з ехінацеєю характеризується в 1,60 рази вищою ефективністю та в 1,70 рази коротшим терміном профілактики твари
Етичні проблеми використання штучного інтелекту та способи їх подолання
No full textThis work discusses the ethical challenges surrounding artificial intelligence (AI) and proposes solutions to navigate them responsibly. AI's growing presence raises concerns about data privacy, bias, intellectual property rights, liability, and potential job displacement. The author suggests increased transparency in data use, development of fair algorithms, legal regulations, public education, and expert collaboration to ensure AI development serves humanity ethically
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