17 research outputs found
Manuale di prevenzione dentale. Per la nutrizione e l'odontoiatria. Per l'igiene dentale
No full textDa tempo si sentiva l’esigenza in ambito scientifico di produrre un testo che contenesse in modo completo ed esaustivo tutto ciò che bisogna sapere in merito alla prevenzione dentale, soprattutto se si osserva il notevole progresso fatto negli ultimi decenni
dalla medicina in questo campo. Infatti, le acquisizioni recenti da un punto di vista
nutrizionale ed odontoiatrico non riguardano solamente la sfera della terapia, ma anche quella della prevenzione. Inoltre, l’interesse delle Scienze della Nutrizione ormai è
rivolto decisamente anche verso l’Odontoiatria e, conseguentemente, verso quella materia strettamente connessa a tale branca della medicina e denominata Igiene Dentale
The preventive care of medication-related osteonecrosis of the jaw (MRONJ): a position paper by Italian experts for dental hygienists
No full textPurpose The prevention and early diagnosis of medication-related osteonecrosis of the jaw (MRONJ) is fundamental to reducing the incidence and progression of MRONJ. Many in the field believe that dental hygienists should play an integral role in primary and secondary MRONJ prevention. However, to date, very few publications in the literature have proposed standardised MRONJ protocols, which are dedicated to dental hygienists. The aim of this study was to provide guidance to the health care providers managing MRONJ.Methods The expert opinion in this study was developed by dental hygienists from the main Italian technical-scientific associations (Italian Dental Hygienists Association, AIDI and National Union of Dental Hygienists, UNID) and authors of the latest Italian recommendations regarding MRONJ from the field of dentistry and maxillofacial surgery.Results The oral care protocol outlined in this position paper is focused on the role of dental hygienist in patients at risk or affected by MRONJ, and it regards 3 main issues: primary prevention, secondary prevention and supporting the treatment of MRONJ. Each issue contains easy-to-apply indications and procedures, as described by the authors, regarding the role of the dental hygienist.Conclusion Referring to the main issues under consideration (primary prevention, secondary prevention and the treatment of MRONJ), a clinical examination of periodontal tissue is critical in preventing MRONJ. It is the opinion of the authors of this study that the application of a periodontal screening score is fundamental in defining personalised strategies for patients at risk of MRONJ. By means of these basic procedures, a protocol for assisting the health care provider and the presentation of a practical approach for patients at risk or affected by MRONJ are described in this study
San Felipe los Alzati: Michoacán
No full textLa información de esta miniguía se basa en los trabajos de los arqueólogos Otto Schondube Baumbach, Jesús Teja Andrade, Wanda Tomassi de Magrelli y Estela Peña DelgadoEl asentamiento formaba parte de la frontera oriente del señorío tarasco. Se desconoce el nombre prehispánico del lugar; en la época colonial se llamó San Felipe Calvario, y en 1895, éste último se le cambió por el apellido Los Alzati, en honor de los hermanos José María, Marcos y Darío, héroes locales de la época de la intervención francesa. Las exploraciones arqueológicas llevadas a cabo en el sitio han sido escasas, por lo que sólo se ha descubierto una pequeña parte que corresponde a la zona ceremonial, ésta es, el área visitable.</p
The Ecovillage of Pescomaggiore (L'Aquila) Birth and death of a self-determined post-disaster community (2009-2014)
No full textPurpose - The purpose of this paper is to aim at exploring the relationship between community building and the changes occurred in the context of a post-disaster self-built ecovillage (EcoVillaggio Autocostruito (EVA)), spontaneously born after the L'Aquila earthquake in 2009. The community eventually dissolved in 2014, following a series of changes in the organization, that resulted in an increasingly centralized decision-making process, and in individual and community relationships, that were fueled by conflicts and contrasts. Design/methodology/approach - Through a self-ethnography method, the paper provides the insider perspective of the lead author who was a part of EVA since the beginning. Self-ethnography allowed developing a narrative of EVA across its life course. Findings - Findings reveal that the community into EVA was initially pursuing community-building goals through self-construction, sustainability, mutuality and reciprocity relationships out of market. However, several events occurred and changed community goals, organization and decision making. Eventually, individual goals and vertical decision making emerged among the community members, leading to the death of EVA. Research limitations/implications - The paper just considered those main events that marked the collective and individual life of the lead author since the beginning until the end of the ecovillage. Others events, equally important, were not considered due to word length. In addition, self-ethnography is still considered by some authors as a subjective method. Originality/value - The paper is one of the few exploring community experiences into post-disaster ecovillages. Moreover, there are no papers investigating post-disaster ecovillages through a self-ethnography approach. Therefore, the paper offers an innovative and original perspective on the under-investigated topic of post-disaster ecovillages and employs a promising research method in disaster studies
Roberto Mariani architetto: senza clamore e dissonanze
No full text“Senza clamore e dissonanze” in queste semplici parole si può racchiudere il complesso lavoro dell’architetto Mariani, sopito per più di un decennio in un apparente silenzio che invece ha molto da raccontare. Sono i racconti, in tono confidenziale, di amici e colleghi a rivelare Roberto Mariani uomo e architetto. Egli, nel corso della sua attività professionale, si occupa di design, edilizia, elabora proposte urbanistiche e partecipa a numerosi concorsi vincendo importanti premi di architettura.
Dalla sede della federazione del Partito Comunista Italiano in via Fratti (1964-1967), opera progettata con Francesco Tomassi, al recupero delle Corti di San Domenico in corso Italia (1987-1991); dalla sistemazione dell’isolato di via Titta Ruffo, via Garofani e corso Italia (1982-1991), al complesso residenziale di via Contessa Matilde, nell’area prima occupata dall’Istituto Opoterapico (1988-1991); dal complesso ippico “Scuderie Nuove” in località Barbaricina (1992-1993), al nuovo cimitero di Cascina (1975-1987); fino ad arrivare all’ultima sua opera, il Polo Didattico Giovanni Carmignani dell’Università di Pisa (1992-2003). Il catalogo ripercorre le tappe principali del lavoro dell’architetto, filtrato attraverso una scrupolosa analisi condotta nell’ampio archivio di architettura di Roberto Mariani. “Uno nato al Portone”, come amava definirsi Mariani, un uomo di quartiere, un intellettuale con un profondo substrato culturale continuamente nutrito da una curiosità per l’architettura e per la vita. A quindici anni dalla sua scomparsa “l’attività professionale di Mariani rimane un significativo riferimento da seguire per trarne insegnamenti, comparazioni, stimoli o critiche, mai qualcosa di trascurabile”. Si affida dunque alle pagine di questo catalogo l’avventura umana e professionale di un architetto pisano del Novecento
Managing living marine resources in a dynamic environment: The role of seasonal to decadal climate forecasts
No full textRecent developments in global dynamical climate prediction systems have allowed for skillful predictions of climate variables relevant to living marine resources (LMRs) at a scale useful to understanding and managing LMRs. Such predictions present opportunities for improved LMR management and industry operations, as well as new research avenues in fisheries science. LMRs respond to climate variability via changes in physiology and behavior. For species and systems where climate-fisheries links are well established, forecasted LMR responses can lead to anticipatory and more effective decisions, benefiting both managers and stakeholders. Here, we provide an overview of climate prediction systems and advances in seasonal to decadal prediction of marine-resource relevant environmental variables. We then describe a range of climate-sensitive LMR decisions that can be taken at lead-times of months to decades, before highlighting a range of pioneering case studies using climate predictions to inform LMR decisions. The success of these case studies suggests that many additional applications are possible. Progress, however, is limited by observational and modeling challenges. Priority developments include strengthening of the mechanistic linkages between climate and marine resource responses, development of LMR models able to explicitly represent such responses, integration of climate driven LMR dynamics in the multi-driver context within which marine resources exist, and improved prediction of ecosystemrelevant variables at the fine regional scales at which most marine resource decisions are made. While there are fundamental limits to predictability, continued advances in these areas have considerable potential to make LMR managers and industry decision more resilient to climate variability and help sustain valuable resources. Concerted dialog between scientists, LMR managers and industry is essential to realizing this potential.Peer reviewe
Chromatin and oxygen sensing in the context of JmjC histone demethylases
No full textResponding appropriately to changes in oxygen availability is essential for multicellular organism survival. Molecularly, cells have evolved intricate gene expression programmes to handle this stressful condition. Although it is appreciated that gene expression is co-ordinated by changes in transcription and translation in hypoxia, much less is known about how chromatin changes allow for transcription to take place. The missing link between co-ordinating chromatin structure and the hypoxiainduced transcriptional programme could be in the form of a class of dioxygenases called JmjC (Jumonji C) enzymes, the majority of which are histone demethylases. In the present review, we will focus on the function of JmjC histone demethylases, and howthese could act as oxygen sensors for chromatin in hypoxia. The current knowledge concerning the role of JmjC histone demethylases in the process of organism development and human disease will also be reviewed. © 2014 The Author(s) This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC-BY).</p
Rapid Subcutaneous Migration of Dirofilaria repens Nematode in Facial Tissue, Italy
No full textWe report a Dirofilaria repens nematode infection in a woman in Italy who sought care for a fast-creeping lesion within her subcutaneous facial tissue. Dirofilariosis should be included in differential diagnosis of subcutaneous nodules or creeping lesions. This case highlights the need for controlling canine dirofilarioses to mitigate zoonotic risk
Consensus Report of the Technical-Scientific Associations of Italian Dental Hygienists and the Academy of Advanced Technologies in Oral Hygiene Sciences on the Non-Surgical Treatment of Peri-Implant Disease
No full textBackground: The recent publication of the new classification of periodontal and peri-implant disease has given clear indications on the parameters to be taken into consideration to correctly diagnose the different phases of these diseases. To date, however, there are no equally clear indications on the treatments to be implemented to solve these diseases. The objective of this Consensus Report is to provide guidance for the non-surgical management of peri-implant mucositis and peri-implantitis. For the drafting of the consensus, the most recent scientific literature was analysed. Materials and Methods: A group of 15 expert Italian dental hygienists were selected by the Italian technical-scientific societies (AIDI, UNID and ATASIO) and, starting from the literature review, they formulated indications according to the GRADE method (Grading of Recommendations, Assessment, Development, and Evaluation, a tool for rating the quality of evidence, used to draw up systematic reviews and clinical guidelines) on the treatment of peri-implant mucositis, peri-implantitis and on management of the various implanting surfaces. Conclusions: in accordance with the international literature, non-surgical therapy alone can resolve peri-implant mucositis, but not peri-implantitis. Several adjunctive therapies have been considered and some appear to be helpful in managing inflammation
β‐Cyclodextrin Inclusion Complexes with Model Pentapeptides: Role of the Tyrosine Position within the Peptide Chain
No full textPeptide's applications frequently present problems of solubility, stability, activity, or membrane permeability. To overcome these issues, cyclodextrins (CDs) can be used to form inclusion complexes with peptide hydrophobic parts; alkyl‐chains or aromatic‐rings inclusion strongly influences the interacting peptide properties. The study of model tripeptides has revealed that, among the three aromatic amino acids, tyrosine is the best suited to be included within CDs. The interaction with β‐CD of five model peptides (Tyr1‐5), each constituted by one tyrosine and four alanines, is reported: the tyrosine occupies one of the five position within each peptide chain. Among natural CDs, β‐CD has been chosen as it is the most economic, used, and only moderately toxic; its cavity size is the best suited to accommodate the tyrosine ring. Stoichiometry and affinity of each complex are evaluated and in silico and experimental data to describe the molecular determinants of each interaction are combined. The data further defines the role of the aromatic ring position in dictating the stability of formed complexes and demonstrates Tyr3, with its central Tyr, as the most stable complex. Noteworthy, the interaction with β‐CD induces Tyr3 to assume a U‐shaped conformation representing a nice example of conformation stabilization upon formation of inclusion complexes
