182 research outputs found

    Estudo da atividade biológica de Baccharis articulata, Musa x paradisiaca e rutina na homeostasia da glicose em modelos experimentais in vivo e in vitro

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    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaA insulina é o principal hormônio anabólico responsável pelo controle da captação, utilização e armazenamento dos nutrientes celulares como carboidratos, proteínas e lipídios, sendo essencial para a manutenção da homeostasia da glicose, o crescimento e diferenciação celular. Defeitos na ação e/ou na secreção de insulina podem levar à hiperglicemia, característica da diabetes melito. A diabetes melito é uma patologia complexa e multifatorial de elevada morbidade e mortalidade e, por esse motivo, é considerada uma epidemia, caracterizando um problema de saúde pública mundial. Muitas plantas são conhecidas na medicina popular de diferentes culturas pelas propriedades hipoglicemiantes e tem um uso crescente no tratamento da diabetes. Os compostos fenólicos derivados de plantas, especialmente os flavonóides, apresentam diversas propriedades e tem um potencial terapêutico muito investigado. O presente trabalho teve como objetivo caracterizar o efeito de extratos e frações de Bacharis articulata (carqueja) e de Musa x paradisiaca (banana), assim como do flavonóide rutina, na homeostasia da glicose em modelos experimentais in vivo e in vitro. As duas espécies foram avaliadas quanto às atividades anti-hiperglicêmica e/ou hipoglicemiante na curva de tolerância à glicose e em modelos de diabetes induzidos experimentalmente, como a secreção de insulina, o conteúdo de glicogênio hepático e muscular, a inibição das enzimas ?-glicosidases e a propriedade anti-glicação, assim como o conteúdo de flavonóides. Além disso, foi estudado o mecanismo de ação da rutina na captação de glicose e de cálcio em músculo sóleo, e também a secreção de insulina in vivo e o mecanismo de ação da rutina na captação de cálcio em ilhotas pancreáticas isoladas. Para tanto, foram utilizados ratos Wistar machos entre 50-55 dias de idade. Para a realização da curva de tolerância à glicose as coletas de sangue, para determinação da glicose e insulina sérica, foram realizadas nos tempos zero, 15, 30, 60, 120 e 180 minutos. Nos ensaios para a determinação do conteúdo de glicogênio os tecidos foram retirados dos animais 3 h após os tratamentos. As atividades das dissacaridases intestinais e a propriedade anti-glicação foram realizadas in vitro. A captação de 14C-glicose e de 45-cálcio (45Ca2+) foi estudada após a incubação do músculo sóleo com a rutina. As ilhotas pancreáticas foram isoladas e incubadas com 45Ca2+ e rutina, na presença ou não de diferentes inibidores e ativadores. Os extratos brutos, as frações n-butanol e residual aquosa de B. articulata e de M. x paradisiaca reduziram significativamente a glicemia de ratos normais hiperglicêmicos e potencializaram a secreção de insulina induzida por glicose. Além disso, observou-se um aumento no conteúdo de glicogênio no músculo sóleo e fígado após os tratamentos, principalmente com as frações n-butanol das duas espécies vegetais. Os extratos e as frações reduziram a atividade da maltase e preveniram a glicação. A rutina estimulou a captação de glicose e cálcio no músculo, estimulando a captação de glicose através da ativação de uma via insulinomimética e uma via independente da sinalização clássica da insulina. Além disso, a rutina estimulou a secreção de insulina in vivo e a captação de cálcio em ilhotas pancreática isoladas, atuando como um potencial agente secretagogo de insulina. Desta forma, apoiado nos resultados obtidos neste trabalho, propõe-se que as espécies vegetais, Baccharis articulata e Musa x paradisiaca, e o flavonóide rutina aqui estudados possam regular a homeostasia da glicose. Os mecanismos envolvem a inibição da enzima que permite a absorção intestinal da glicose, a inibição da glicação, o estímulo da secreção de insulina e o aumento na utilização de glicose pelos tecidos periféricos, evidenciando que estas duas espécies e a rutina podem atuar por múltiplos mecanismos de ação para regular a homeostasia da glicose e colaborar na prevenção das complicações da diabetes.Insulin is the main anabolic hormone responsible for controlling the uptake, use and storage of cellular nutrients such as carbohydrates, proteins and lipids. It is essential for the maintenance of glucose homeostasis, growth and cellular differentiation. Defects in action and / or secretion of insulin may lead to hyperglycemia, which characterizes diabetes mellitus. Diabetes mellitus is a complex and multifactorial disease with high morbidity and mortality, therefore is considered epidemic causing a public health problem worldwide. Many plants are known in folk medicine of different cultures for their hypoglycemic properties showing an increasing use in the treatment of diabetes. The plant-derived phenolic compounds, especially flavonoids, have several properties and their therapeutic potential has been investigated. The aim of this study was to characterize the effect of extracts and fractions of Baccharis articulata ("carqueja") and Musa x paradisiaca ("banana"), as well as the flavonoid rutin, in glucose homeostasis using in vivo and in vitro experimental models. Antihyperglycemic and / or hypoglycemic activity in the curve of glucose tolerance and in models of experimentally induced diabetes, insulin secretion, the hepatic glycogen content and muscle, inhibition of the enzymes á-glucosidases and anti-glycation property were investigated, as well as the content of flavonoids. In addition, was also studied the mechanism of action of rutin in glucose and calcium uptake in soleus muscle, and also the in vivo insulin secretion and the mechanism of action of rutin on calcium uptake in rat isolated pancreatic islets. For in vivo experiments, Wistar male rats with 50-55 days of age were used. To glycemia and serum insulin determination blood samples were collected at zero, 15, 30, 60, 120 and 180 min in glucose tolerance curve. Tissues were removed from animals 3 h after oral administration of treatments to determine glycogen contents. The intestinal disaccharidases activities and anti-glycation property were performed in vitro. The glucose and calcium uptake was studied after incubation of the soleus muscle with rutin, in the presence or not of different inhibitors and of 14C-glucose or calcium (45Ca2+). The pancreatic islets were isolated and incubated with 45Ca2+ and rutin in the presence or absence of various inhibitors or activators. The crude extracts and n-butanol and residual aqueous fractions of B. articulata and of M. x paradisiaca showed potential anti-hyperglycemic activity in hyperglycemic normal rats and potentiated glucose-induced insulin secretion. Additionaly, it was observed an increase on glycogen content in muscle and liver after treatments, mainly with the n-butanol fractions of two species. The extracts and fractions reduced the activity of maltase and prevented glycation. Also, rutin stimulated glucose and calcium uptake in soleus muscle, stimulating glucose uptake via activation of an insulin-mimetic and an insulin-independent signaling pathways. Additionally, rutin stimulated insulin secretion in vivo and calcium uptake in isolated pancreatic islets, as a potential insulin secretagogue agent. Thus, these results suggest that Baccharis articulata, M. x paradisiaca and rutin are able to regulate glucose homeostasis. The mechanisms involve the inhibition of the enzyme that allows the intestinal absorption of glucose, the inhibition of glycation, the stimulation of insulin secretion and increase in glucose utilization by peripheral tissues showed that these plant species and rutin may act by multiple mechanisms of action to regulate glucose homeostasis, thereby contributing to the prevention of diabetes-related complications

    Effect of 1-month war in Lebanon on sex ratio

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    Our study showed no effect of 33-day war in Lebanon on sex ratio. More research is needed to explore other modifying factors for a better understanding of the complex effect of wars on sex ratio changes. © 2009 American Society for Reproductive Medicine.Abu-Musa A, 2008, REPROD BIOMED ONLINE, V17, P21; Abu-Musa AA, 2007, FERTIL STERIL, V88, P1579, DOI 10.1016-j.fertnstert.2007.01.067; Ansari-Lari M, 2002, J EPIDEMIOL COMMUN H, V56, P622, DOI 10.1136-jech.56.8.622; Bisioli C, 2004, HUM REPROD, V19, P218, DOI 10.1093-humrep-deh027; *CAP OCHA, 2006, LEB CRIS FLASH APP; Catalano R., 2003, HUM REPROD, V9, P1972; Catalano RA, 2005, SOC SCI MED, V60, P537, DOI 10.1016-j.socscimed.2004.06.008; *CENTR ADM STAT PR, LEB REP; Fukuda M, 1996, HUM REPROD, V11, P1244; Fukuda M, 1998, HUM REPROD, V13, P2321, DOI 10.1093-humrep-13.8.2321; Graffelman J, 2000, HUM BIOL, V72, P433; Grech V, 2000, J EPIDEMIOL COMMUN H, V54, P244, DOI 10.1136-jech.54.4.244; Hansen D, 1999, BRIT MED J, V319, P548; Hilsenrath RE, 1997, FERTIL STERIL, V68, P510, DOI 10.1016-S0015-0282(97)00247-1; Jacobsen R, 2000, HUM REPROD, V15, P2369, DOI 10.1093-humrep-15.11.2369; James WH, 2004, HUM REPROD, V19, DOI 10.1093-humrep-deh261; James WH, 2004, HUM REPROD, V19, P1250, DOI 10.1093-humrep-deh245; James WH, 2003, HUM REPROD, V18, P1133, DOI 10.1093-humrep-deg220; Mathews T J, 2005, Natl Vital Stat Rep, V53, P1; Mocarelli P, 2000, LANCET, V355, P1858, DOI 10.1016-S0140-6736(00)02290-X; Moller H, 1996, LANCET, V348, P828, DOI 10.1016-S0140-6736(05)65253-1; Polasek O, 2005, HUM REPROD, V20, P2489, DOI 10.1093-humrep-dei097; Safarinejad MR, 2001, UROLOGY, V58, P90, DOI 10.1016-S0090-4295(01)01085-8; Shearer D, 2007, DISASTERS, V31, P336, DOI 10.1111-j.0361-3666.2007.01012.x; vandenBroek JM, 1997, LANCET, V349, P805, DOI 10.1016-S0140-6736(05)60234-6; Zorn B, 2002, HUM REPROD, V17, P3173, DOI 10.1093-humrep-17.12.317311

    Effect of the Lebanese civil war on sex ratio

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    Sex ratio is a subject of scientific interest but little is known about the factors that affect the sex ratio of humans. The aim of this study was to assess the effect of the Lebanese civil war on sex ratio. Data on all live births delivered at a large university hospital for the years 1977-2005 were used in this study. Study periods were defined as wartime (1977-1992) and post-war (1993-2005). The sex ratio in the study time period was calculated as the male proportion, i.e. males-males + females in live-born infants. Sex ratio during the war was compared with that of the post-war period. The sex ratio was similar in the war and post-war period (0.515 versus 0.513; OR = 1.007; 95percent CI 0.98-1.04). The annual variation in the sex ratio during the study period did not show any significant change in any of the years. In conclusion, the Lebanese civil war did not cause a detectable change in sex ratio at birth. Factors that might have affected the sex ratio include the nature of the study population (civilians), the variable intensity of war in different periods, and the effect of stress and environmental toxins. © 2008 Published by Reproductive Healthcare Ltd.Abu-Musa AA, 2007, FERTIL STERIL, V88, P1579, DOI 10.1016-j.fertnstert.2007.01.067; Ansari-Lari M, 2002, J EPIDEMIOL COMMUN H, V56, P622, DOI 10.1136-jech.56.8.622; Bisioli C, 2004, HUM REPROD, V19, P218, DOI 10.1093-humrep-deh027; Catalano R., 2003, HUM REPROD, V9, P1972; Catalano RA, 2005, SOC SCI MED, V60, P537, DOI 10.1016-j.socscimed.2004.06.008; Erickson K, 2001, J CLIN ENDOCR METAB, V86, P2544, DOI 10.1210-jc.86.6.2544; Fisher RA, 1930, GENETICAL THEORY NAT; Fukuda M, 1996, HUM REPROD, V11, P1244; Graffelman J, 2000, HUM BIOL, V72, P433; Grech V, 2000, J EPIDEMIOL COMMUN H, V54, P244, DOI 10.1136-jech.54.4.244; Hamdan F, 2002, LEBANON'S SECOND REPUBLIC: PROSPECTS FOR THE TWENTY-FIRST CENTURY, P175; Hansen D, 1999, BRIT MED J, V319, P548; Hobel CJ, 1999, AM J OBSTET GYNECOL, V180, pS257, DOI 10.1016-S0002-9378(99)70712-X; Jabbra NW, 2004, J COMP FAM STUD, V35, P259; Jacobsen R, 2000, HUM REPROD, V15, P2369, DOI 10.1093-humrep-15.11.2369; James WH, 2004, HUM REPROD, V19, DOI 10.1093-humrep-deh261; James WH, 2004, HUM REPROD, V19, P1250, DOI 10.1093-humrep-deh245; James WH, 2003, HUM REPROD, V18, P1133, DOI 10.1093-humrep-deg220; JAMES WH, 1987, HUM BIOL, V59, P721; James WH, 1996, J THEOR BIOL, V180, P271, DOI 10.1006-jtbi.1996.0102; JOSEPH S, 1994, SOCIAL POLITICS, V1, P270; LYSTER WR, 1974, J OBSTET GYN BR COMM, V81, P626; MAYNARDSMITH J, 1980, BEHAV ECOL SOCIOBIOL, V7, P247; Mocarelli P, 2000, LANCET, V355, P1858, DOI 10.1016-S0140-6736(00)02290-X; Moller H, 1996, LANCET, V348, P828, DOI 10.1016-S0140-6736(05)65253-1; Polasek O, 2005, HUM REPROD, V20, P2489, DOI 10.1093-humrep-dei097; Polasek O, 2006, EUR J EPIDEMIOL, V21, P61, DOI 10.1007-s10654-005-4845-7; ROSE RM, 1969, PSYCHOSOM MED, V31, P418; Saxena PC, 2004, J COMP FAM STUD, V35, P241; SEMPLE CG, 1986, BRIT MED J, V293, P1049; Sureau C, 1999, HUM REPROD, V14, P867, DOI 10.1093-humrep-14.4.867; Trivers R., 1985, SOCIAL EVOLUTION; vandenBroek JM, 1997, LANCET, V349, P805, DOI 10.1016-S0140-6736(05)60234-6; vanderPaldeBruin KM, 1997, LANCET, V349, P62, DOI 10.1016-S0140-6736(05)62204-0; Zorn B, 2004, HUM REPROD, V19, P219, DOI 10.1093-humrep-deh026; Zorn B, 2002, HUM REPROD, V17, P3173, DOI 10.1093-humrep-17.12.317323

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    Impacts of Motorcycle Dedicated Lanes on Traffic Flow and Safety of Unsignalized Intersections–A Microsimulation Case Study in Kampala, Uganda

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    Traffic congestion and undeveloped public transport define the modus operandi in Kampala, the capital city of Uganda. Most people see motorcycles as a solution to escape the growing traffic congestion and poor public transport. This study thus aimed to determine the traffic efficiency and safety effectiveness of introducing motorcycle dedicated lanes in non–lane based and mixed traffic. These effects were studied by microsimulation of unsignalized intersections without priority markings in urban areas of developing countries. The study centered on an intersection commonly known as “Spear Motors” in Kampala. In addition, off-peak traffic was simulated since traffic police controls the intersection during peak time and microsimulation model cannot simulate traffic while a policeman (or two) is on duty.Video images of the intersection were officially obtained from Uganda Police and processed to traffic data such as traffic volume, trajectories, composition, and conflicts. In addition, geometric data (lane width, slope, intersection dimensions, coordinates, and aerial pictures) about the intersection was physically collected during a daytime site visit.A representation of the current traffic conditions at the intersection, referred to as the base model, was developed in VISSIM 21. The base model was calibrated using Particle Swarm Optimization (PSO). Thereafter, the model was microscopically and macroscopically validated. Three scenarios were considered in this study, which are: scenario 1 with straight crossings of motorcycles in the intersection, scenario 2 with deflected crossings and scenario 3 with a roundabout separated for the main road traffic and motorcycles.Simulations with driver behavior parameters set to optimum values were performed to replicate the actual behavior. Consequently, traffic conflicts were generated from vehicle trajectories per scenario. Post Encroachment Time (PET) and Time to Collision (TTC) were calculated for the conflicts. The use of conflicts is proactive compared to reactive approaches that use crashes.The use of deflected crossings for motorcycles and then a roundabout separated for main traffic and motorcycles increased the flow of the intersection by 31% and 20%, respectively. Additionally, the implementation of deflected motorcycle crossings and roundabout reduced critical density by 38.6% and 63.7%, respectively.Regarding safety, more benefits are expected by using either deflected crossings or roundabout than straight crossings. The number of severe critical conflicts reduced by 87.9% with the application of a roundabout separated for main road traffic and motorcycles. This is higher than the decrease of 48.5% after the application of dedicated motorcycle lanes with deflected crossings. To determine the conflict rates per scenario, the number of severe critical conflicts was divided by total traffic simulated. Deflected crossings for motorcycles reduced severe critical conflict rate by 40% whilst it decreased by 75% with intersection improvement to a roundabout separated for main traffic and motorcycles.With the high motorcycle demand of over 50% of traffic, implementation of dedicated motorcycle lanes at unsignalized intersections as well as urban roads in general will result into better flow of traffic. In addition, the motorcycle lanes will contribute to the general road safety in Kampala.Civil Engineering | Transport and Plannin

    Effect of war on fertility: A review of the literature

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    The aim of this study was to review the existing literature on the effect of war on female and male fertility. A MEDLINE search for studies that included participants defined as infertile because they were unsuccessful in achieving a pregnancy after a year and studies that assessed the effect of war on semen parameters and menstrual dysfunction were performed. Twenty articles were included in this review. For female fertility, studies showed that women who were prisoners of war or who were living in areas exposed to bombardment had increased risk of menstrual abnormalities. For male fertility, the results were conflicting. The Vietnam War was not associated with difficulty in conception although one study revealed a decrease in sperm characteristics. Studies of male US and Danish 1990-91 Gulf war veterans showed no evidence of reduced fertility; however, studies of UK and Australian veterans reported increased risk of infertility. The Lebanese and Slovenian civil wars were associated with a decrease in sperm parameters. Exposure to mustard gas was also associated with abnormal semen parameters; however, exposure to depleted uranium had no effect on semen characteristics. Most of the studies examined had major limitations including recall bias and small number of cases included. © 2008 Published by Reproductive Healthcare Ltd.Abu-Musa AA, 2007, FERTIL STERIL, V88, P1579, DOI 10.1016-j.fertnstert.2007.01.067; Araneta MRG, 2003, BIRTH DEFECTS RES A, V67, P246, DOI 10.1002-bdra.10033; Arfsten DP, 2006, ENVIRON RES, V100, P205, DOI 10.1016-j.envres.2005.03.016; Azizi F, 1995, Med War, V11, P34, DOI 10.1080-07488009508409195; BASS F, 1947, GYNAECOLOGIA, V123, P11; BENTS H, 1985, INT J ANDROL, V8, P325, DOI 10.1111-j.1365-2605.1985.tb00845.x; Bigelow PL, 1998, FERTIL STERIL, V69, P11, DOI 10.1016-S0015-0282(97)00437-8; BLOT WJ, 1972, AM J HUM GENET, V24, P613; Cowan DN, 1997, NEW ENGL J MED, V336, P1650, DOI 10.1056-NEJM199706053362306; Cui KH, 1996, HUM REPROD, V11, P568; Daniels JL, 1997, ENVIRON HEALTH PERSP, V105, P1068, DOI 10.1289-ehp.971051068; Demir S C, 2000, J Pediatr Adolesc Gynecol, V13, P171, DOI 10.1016-S1083-3188(00)00061-9; DESTEFANO F, 1989, REPROD TOXICOL, V3, P165, DOI 10.1016-0890-6238(89)90003-8; Domingo JL, 2001, REPROD TOXICOL, V15, P603, DOI 10.1016-S0890-6238(01)00181-2; Doyle P, 2004, INT J EPIDEMIOL, V33, P74, DOI 10.1093-ije-dyh049; Fenster L, 1997, J ANDROL, V18, P194; Fenster L, 1999, AM J EPIDEMIOL, V149, P127; FILICORI M, 1993, HUM REPROD, V8, P62; Fukuda M, 1998, HUM REPROD, V13, P2321, DOI 10.1093-humrep-13.8.2321; GERHARD I, 1992, HUM REPROD, V7, P830; Ghanei M, 2004, REPROD TOXICOL, V18, P635, DOI 10.1016-j.reprotox.2004.03.003; GIBLIN PT, 1988, FERTIL STERIL, V49, P127; GUYTON AC, 1989, TXB MED PHYSL; Hamdan F, 2002, LEBANON'S SECOND REPUBLIC: PROSPECTS FOR THE TWENTY-FIRST CENTURY, P175; Hannoun AB, 2007, OBSTET GYNECOL, V109, P929, DOI 10.1097-01.AOG.0000257170.83920.de; Hjollund NHI, 1999, FERTIL STERIL, V72, P47, DOI 10.1016-S0015-0282(99)00186-7; Ishoy T, 2001, DAN MED BULL, V48, P29; JEYASEELAN L, 1995, HUM BIOL, V67, P283; Kang H, 2001, ANN EPIDEMIOL, V11, P504, DOI 10.1016-S1047-2797(01)00245-9; Kelsall HL, 2007, BMC PUBLIC HEALTH, V7, DOI 10.1186-1471-2458-7-79; KOBEISSI L, 2007, FERTILITY IN PRESS; KREUZ LE, 1972, ARCH GEN PSYCHIAT, V26, P479; Maconochie N, 2004, BRIT MED J, V329, P196, DOI 10.1136-bmj.38163.620972.AE; McDiarmid MA, 2004, J TOXICOL ENV HEAL A, V67, P277, DOI 10.1080-15287390490273541; McDiarmid MA, 2006, INT ARCH OCC ENV HEA, V79, P11, DOI 10.1007-s00420-005-0006-2; McDiarmid MA, 2007, HEALTH PHYS, V93, P60, DOI 10.1097-01.HP.0000259850.66969.8c; McDiarmid MA, 2001, J OCCUP ENVIRON MED, V43, P991; MCGRADY AV, 1984, ARCH ANDROLOGY, V13, P1; MOGHISSI KS, 1983, FERTIL STERIL, V39, P5; NORMAN RL, 1992, NEUROENDOCRINOLOGY, V55, P405, DOI 10.1159-000126151; OLSHAN AF, 1991, AM J IND MED, V20, P447, DOI 10.1002-ajim.4700200403; Pasternak A, 2007, J MINIM INVAS GYN, V14, P211, DOI 10.1016-j.jmig.2006.10.026; Penman AD, 1996, MIL MED, V161, P1; Petit NF, 1996, WOMEN HEALTH ISS, V6, P358; RAYMONDWHISH S, ENV HLTH PERSPECTIVE, V115, P1711; Safarinejad MR, 2001, UROLOGY, V58, P90, DOI 10.1016-S0090-4295(01)01085-8; SATO PA, 1999, P C FED SPONS GULF W, P37; Savitz DA, 1997, AM J EPIDEMIOL, V146, P1025; SEIGEL DG, 1966, RADIAT RES, V28, P278, DOI 10.2307-3572196; SIM M, 2003, AUSTR GULF VETERANS, V2; STELLMAN SD, 1988, ENVIRON RES, V47, P150, DOI 10.1016-S0013-9351(88)80039-2; Speroff L, 2005, CLIN GYNECOLOGIC END, P465; Squibb KS, 2006, PHILOS T ROY SOC B, V361, P639, DOI 10.1098-rstb.2006.1823; STEVE H, 1952, FLUSS NERVEN SYSTEM; *US GEN ACC OFF, 1994, OP DES STORM QUEST P, P94; Wardell D W, 2001, J Am Acad Nurse Pract, V13, P187; WARREN MP, 1983, ENDOCR REV, V4, P363; WELCH LS, 1988, AM J IND MED, V14, P509, DOI 10.1002-ajim.4700140503; Whitacre Frank E., 1944, JOUR AMER MED ASSOC, V124, P399; World Health Organization, 1999, WHO LAB MAN EX HUM S; Wynn Arthur, 1993, Nutrition and Health (Bicester), V9, P43; Zorn B, 2002, HUM REPROD, V17, P3173, DOI 10.1093-humrep-17.12.317345

    Telchin licus subsp. laura H. Druce 1896

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    Telchin licus laura (H. Druce, 1896) (Fig. 8) Castnia laura H. Druce, 1896 Taxonomic history. The ssp. was originally described (as Castnia laura) by Herbert Druce (1896). Miller (1995) considered it a synonym of Leucocastnia licu s (Drury) and Lamas (1995) placed it as a ssp. of Telchin licus (Drury). Benítez (2002) mentions Castnia sora (= Synpalamides phalaris) and Castnia licus in his list of forest and agricultural pests of Paraguay based on specimens deposited at the FCA/ DE. The first author visited this collection in 2009 and only saw specimens of Synpalamides phalaris (Fabricius), Castnia invaria penelope Schaufuss and Gazera heliconioides micha (H. Druce) deposited there. These facts allow us to conclude that the “ Castnia licus ” mention in Benitez (2002) is just a misspelling of “ Castnia linus ” (= G. heliconioides). Distribution. The type described by Druce is from Chapada dos Guimarães (Mato Grosso, Brazil) (Druce 1896). In a broader sense, Telchin licus (Drury) is found primarily in the Amazon Basin, with subspecies ranging from Honduras to Bolivia (Lamas 1995; González 2003). One specimen collected in 1984, and deposited at the MNHNPY (see below), appears to be the first valid Paraguayan record of the species. It was collected in a region with a mixture of Atlantic Forest and Cerrado vegetation. Biology and behavior. Benítez (2002) reports that this species is a pest of pineapples [Ananas comosus (L.) Merr.; Bromeliaceae] and Bananas (Musa spp.; Musaceae), however we could not autenticate these data in Paraguay since it was part of a host plant literature related to Telchin licus (Drury). Material examined. CANINDEYÚ: 13, 34 km SE of Catueté. 19.II. 1984. Coll. T. Bonace (MNHNPY).Published as part of Ríos, Sergio D. & González, Jorge M., 2011, A synopsis of the Castniidae (Lepidoptera) of Paraguay, pp. 43-61 in Zootaxa 3055 on page 51, DOI: 10.5281/zenodo.27891

    Shifâ'u’l-Qulûb And Ziyâ'u’l-Qubûr (Text And Language Examination)

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    Bu çalışmada, Şeyh Bekir tarafından Hicrî 1143, Miladî 1731 tarihinde yazılan ve Hicrî 1167, Miladî 1754 tarihinde Abdullah isminde bir zat tarafından istinsah edilmiş Şifâéü’l-Kulûb ve Ziyâéü’l-Kubûr adlı eserin tahlili yapılmıştır. Detaylı bir şekilde araştırma yapıldıktan sonra Şifâéü’l-Kulûb ve Ziyâéü’l-Kubûr adlı eserin başka nüshalarına ulaşılamayıp elimizde 1754 tarihinde Abdullah’ın istinsah ettiği ve ulaşabildiğimiz tek nüshanın bu olduğu anlaşılmıştır. Bu eser, İBB Kültür ve Sosyal İşler Daire Başkanlığı Kütüphane ve Müzeler Müdürlüğü’ne bağlı Atatürk Kitaplığı’nda K.657 demirbaşı, 297.85 BEK yer numarası ile kayıtlıdır. Eser, nesih yazı türü ile yazılmış dinî konuları anlatan bir ilmihâl kitabıdır. Dört bölümden oluşan çalışmamızın birinci bölümünde Şifâéü’l-Kulûb ve Ziyâéü’l-Kubûr adlı eser hakkında genel bir bilgi verilmiştir. Eser imlâ ve dil özellikleri bakımından değerlendirilmiştir. Ayrıca müellifi farklı olan ve Türkiye’deki kütüphanelerde bulunan diğer Şifâéü’l-Kulûbler hakkında da bilgi verilmiştir. İkinci bölümde Şifâéü’l-Kulûb ve Ziyâéü’l-Kubûr metnin transkripsiyonu verilmiştir. Üçüncü bölümde metinde geçen kelimelerin anlamlarının ve geçtiği yerlerin belirtildiği bir dizin-sözlük hazırlanmıştır. Dördüncü bölümde metinde geçen özel isimler ve geçtiği yerlerin gösterildiği özel isimler sözlüğü hazırlanmıştır. Son olarak sonuç bölümü ve kaynakçayla beraber çalışma tamamlanmıştır.In this dissertation, the work on Shifâ'u’l-Qulûb and Ziyâ'u’l-Qubûr written by Sheikh Bekir in H. 1143 (AD 1731) was examined. This work was taken over in H.1167 (AD 1754) by Abdullah, who made a copy of the work. After a detailed research, it is understood that another copy of Shifâ'u’l-Qulûb and Ziyâ'u’l-Qubûr cannot be reached, and that it is the only copy that Abdullah made and it dates from 1754. This work is registered with K.657 fixture, 297.85 BEK place number in the Department of Libraries and Museums within the Ministry of Culture and Social Issues of the City of Istanbul (Atatürk Library). The work is a book of knowledge telling religious subjects written in a nesih type of writing. The dissertation consists of four chapters. The first chapter informs about the composition of Shifâ'u’l-Qulûb and Ziyâ'u’l-Qubûr, evaluation of the work in terms of spelling and language features, life and work of the author. This chapter also contains information about the works found in libraries in Turkey which have the same name as the original Shifâ'u’l-Qulûb. The second chapter consists of the transcribed texts of Shifâ'u’l-Qulûb and Ziyâ'u’l-Qubûr. The third chapter consists of a full dictionary which is composed of words from the work and it also contains an index helping a reader locate these words in the text. The fourth chapter determines and classifies proper names in the text. These proper names are represented as a dictionary with an index which helps a reader locate them. The last part of the dissertation consists of a conclusion and bibliography

    LEGAL REGULATION OF THE PRESS IN B&H FROM 1907 TO 1940

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    Ovim člankom obrađuje se problematika pravnoga statusa tiska, tiskarstva i nakladništva u Bosni i Hercegovini od 1907. do 1940. godine. U tekstu se prikazuje kako zakonodavci pristupaju pravu na slobodu izražavanja, slobodu mišljenja, obvezi i pravu radnika i poslodavaca u toj djelatnosti. Donose se i odredbe kojima se dopušta ili zabranjuje objavljivanje tiskovina. Iz Zakona o tisku iz 1907. godine navodi se da nakladnik mora biti državljanin Bosne i Hercegovine, njime se određuju posebne jamčevine u slučaju novčanih kaznâ, uvodi se pravo na ispravak i odgovor i sl. Autor obrađuje i Obznanu, Zakon o zaštiti države iz 1921. i Ustav Kraljevine SHS iz 1921., Zakon o tisku iz 1925., Uredbu o uređenju odnosa između novinara i vlasnika listova iz 1926., Zakon o izmjenama i dopunama zakona o tisku iz 1929. godine. Obznana, uz ostalo, donosi razloge zbog kojih se može zabraniti izdavanje tiskovina, ali sankcije kojima se kažnjava “nepodobno” pisanje i tiskanje. Zakonom o tisku iz 1925. godine reguliraju se kaznena djela klevete i uvrede. Uredbom iz 1926. godine vidno se poboljšava status novinara tako što im se određuju godišnji odmor, otpremnine, otkazni rokovi, a utemeljen je i mirovinski fond za novinare. Zakonom o izmjenama i dopunama zakona o tisku iz 1929. godine zabranjuje se izdavanje oporbenih tiskovina, a i sva prava novinara i nakladnika znatno su ograničena.This article deals with problems of the legal status of press, printing and publishing industry in Bosnia and Herzegovina from 1907 to 1940. The text shows the ways in which legislators approach to the right to freedom of speech, freedom of thinking, duties and rights of employees and employers in that activity, but also the regulations which allow or forbid publishing. From the Law on press from 1907 it is mentioned that the publisher has to be a citizen of Bosnia and Herzegovina, it defines special bails in the case of money punishments, it introduces the right to correction and answer, etc. The author also deals with the Proclamation, State protection law from 1921 and Constitution of the Kingdom of Serbs, Croats and Slovenes from 1921, Law on press from 1925, Regulation about defining relations between journalists and owners of newspapers from 1926, Law on amendments of Law on press from 1923. The Proclamation talks about the way in which publishing can be forbidden, but also about the way in which “inappropriate” writing and printing are punished. The Law on press from 1925 regulates criminal offences such as slanders and insults. Regulation from 1926 significantly improves the status of journalists. It defines their paid vacations, redundancy payments, period of notice and it established the pension fund for journalists. The Law on amendments of Law on press from 1929 forbids publishing the opposition papers and all the rights of journalists and publishers are significantly limited
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