12,225 research outputs found

    Author interview: Q&A with Rachel O’Neill on Seduction: men, masculinity and mediated intimacy

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    In this author interview, we speak to Rachel O’Neill about her recent book, Seduction: Men, Masculinity and Mediated Intimacy, which offers an ethnographic study of the ‘seduction industry’. In the interview, she discusses the seduction industry as part of a continuum of mediated intimacy, the ways in which neoliberal rationalities are shaping masculine subjectivity today, how the book relates to contemporary discussions surrounding consent and women’s sexual agency and the particular challenges of undertaking this fieldwork. If you are interested in this interview, you can read a review of Seduction on LSE RB here. Q&A with Rachel O’Neill, author of Seduction: Men, Masculinity and Mediated Intimacy (Polity, 2018

    Sister Rachel helping child at day nursery

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    L-3056-L shows Sister Rachel washing a child's hands. L-3056-K shows Sister Rachel tying child's shoes.''The Congregation of Divine Providence maintains a day nursery on Dwyer avenue for the children of war worker parents. Sister Rachel, a trained specialist in child care, is a member of the order.'

    Sister Rachel helping child at day nursery

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    L-3056-M shows Sister Rachel clearning child's ear.''The Congregation of Divine Providence maintains a day nursery on Dwyer avenue for the children of war worker parents. Sister Rachel, a trained specialist in child care, is a member of the order.'

    Sister Rachel helping child at day nursery

    No full text
    L-3056-K shows Sister Rachel tying child's shoes.''The Congregation of Divine Providence maintains a day nursery on Dwyer avenue for the children of war worker parents. Sister Rachel, a trained specialist in child care, is a member of the order.'

    Mobile marketing : an hour a day / Rachel Pasqua, Noah Elkin.

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    Includes bibliographical references and index.xxvii, 354 p. :A step–by–step guide to successful mobile marketing strategies Go from zero to sixty with this practical book that helps you craft and deploy mobile marketing strategies for everything from brand building to lead generation and sales. As part of the popular do–it–yourself, Hour A Day series, this new book is full of advice, practical tips, and step–by–step tactics you can put to use right away. Start leveraging location–based marketing via Foursquare and Yelp, see how to set up and manage mobile commerce, and try such technologies as QR codes, ambient communication (RFID and Bluetooth), mobile broadcasting, and more. Take action now and mobile–loving customers will soon find you, thanks to these successful ideas and strategies from expert mobile marketers, Rachel Pasqua and Noah Elkin. Shows you step by step how to develop, implement, and measure a successful mobile marketing strategy Pares down a complex process into approachable, bite–sized tasks you can tackle in an hour a day Covers vital mobile marketing weapons like messaging, mobile websites, apps, and mobile advertising to help you achieve your goals Gets you up to speed on location–based marketing via Foursquare and Yelp, using mobile commerce, and leveraging technologies such as as QR codes, ambient communication (RFID and Bluetooth), and mobile broadcasting Mobile Marketing: An Hour A Day is a must–have resource for marketers and advertisers who want a compelling mobile presence

    Episode 3: Rachel Wightman, CSP Staff and Author

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    In this episode, CSP\u27s Associate Director of Instruction and Outreach, Rachel Wightman, shares about her new book, Faith and Fake News: A Guide to Consuming Information Wisely, including how she became interested in the topic, what led to the creation of this book, and why this topic is so important today

    Rachel Swarns Book Event: The 272

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    A conversation with Rachel Swarns, author of The GU272: The Families Who Were Enslaved And Sold To Build The American Catholic Church (Penguin Random House 2023). The conversation was moderated by Georgetown Professor Adam Rothman and hosted by Georgetown's Center for the Study of Slavery and Its Legacies

    Theodore Clement Steele: A Lecture by Rachel Perry

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    Join author and curator Rachel Perry for a lecture on the life and artwork of Theodore Clement (TC) Steele. Perhaps the most well-known artist of the “Hoosier Group,” Steele created impressionist portraits and landscape paintings from his studio in Nashville, Indiana.https://scholarship.depauw.edu/peeler_event/1084/thumbnail.jp

    Rachel Todd letter to Charity Rotch, Farmington, August 19, 1808

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    Rachel Todd discusses the ongoing problem of caring for the sick effected by fevers that were pervasive in parts of New England. She writes that she came home to find her physician husband "out visiting the sick in the street whom he had not found time to see in the course of the day." 7.7" x 13.5" (19.5 by 32 cm

    Antibody-nanoparticle conjugates to enhance the sensitivity of ELISA-based detection methods

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    Publisher's PDFAccurate antigen detection is imperative for clinicians to diagnose disease, assess treatment success, and predict patient prognosis. The most common technique used for the detection of disease-associated biomarkers is the enzyme linked immunosorbent assay (ELISA). In an ELISA, primary antibodies are incubated with biological samples containing the biomarker of interest. Then, detectible secondary antibodies conjugated with horseradish peroxidase (HRP) bind the primary antibodies. Upon addition of a color-changing substrate, the samples provide a colorimetric signal that directly correlates to the targeted biomarker concentration. While ELISAs are effective for analyzing samples with high biomarker content, they lack the sensitivity required to analyze samples with low antigen levels. We hypothesized that the sensitivity of ELISAs could be enhanced by replacing freely delivered primary antibodies with antibody-nanoparticle conjugates that provide excess binding sites for detectible secondary antibodies, ultimately leading to increased signal. Here, we investigated the use of nanoshells (NS) decorated with antibodies specific to epidermal growth factor receptor (EGFR) as a model system (EGFR-NS). We incubated one healthy and two breast cancer cell lines, each expressing different levels of EGFR, with EGFR-NS, untargeted NS, or unconjugated EGFR antibodies, as well as detectable secondary antibodies. We found that EGFR-NS consistently increased signal intensity relative to unconjugated EGFR antibodies, with a substantial 13-fold enhancement from cells expressing high levels of EGFR. Additionally, 40x more unconjugated antibodies were required to detect EGFR compared to those conjugated to NS. Our results demonstrate that antibody-nanoparticle conjugates lower the detection limit of traditional ELISAs and support further investigation of this strategy with other antibodies and nanoparticles. Owing to their enhanced sensitivity, we anticipate that nanoparticle-modified ELISAs can be used to detect low levels of biomarkers found in various diseases, such as cancers, tuberculosis, and rheumatoid arthritis, and may ultimately enable earlier diagnosis, better prognostication, and improved treatment monitoringUniversity of Delaware. Department of Biomedical Engineering.University of Delaware. Department of Materials Science and Engineering
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